CAS 183499-56-1

Formule : C22H22Cl3N5O

InChI : InChI=1S/C22H20ClN5O.2ClH/c23-19-2-1-3-20(10-19)28-9-8-26(15-22(28)29)14-21-12-25-16-27(21)13-18-6-4-17(11-24)5-7-18;;/h1-7,10,12,16H,8-9,13-15H2;2*1H

Code InChI : XNGJWEBJQJQXQR-UHFFFAOYSA-N

SMILES : C1CN(C(=O)CN1CC2=CN=CN2CC3=CC=C(C=C3)C#N)C4=CC(=CC=C4)Cl.Cl.Cl

L-778123 Dihydrochloride

CAS : 183499-56-1

Formule : C₂₂H₂₀ClN₅O·2HCl

Degré de pureté : >98.0%(HPLC)

Couleur et forme : White to Almost white powder to crystal

Masse moléculaire : 478.80

Ref: 3B-L0337

L-778123 Dihydrochloride

CAS : 183499-56-1

L-778123 Dihydrochloride

Formule : C₂₂H₂₀ClN₅O·2HCl

Degré de pureté : >98%

Masse moléculaire : 478.8

Ref: 54-OR1078635

L-778123 Dihydrochloride

CAS : 183499-56-1

L-778123 blocks FPTase/GGPTase-I, halts Ki-Ras prenylation, has acceptable toxicity with radiotherapy in advanced pancreatic cancer.

Formule : C₂₂H₂₂Cl₃N₅O

Couleur et forme : Solid

Masse moléculaire : 478.802

Ref: TM-T70134

L-778123 Dihydrochloride

CAS : 183499-56-1

L-778123 is a potent, selective inhibitor of Kv1.3 potassium channels with excellent pharmacokinetics and tissue selectivity. It has been used for in vitro research to study the role of ion channels in cell biology and pharmacology, as well as for the development of new drugs to treat diseases such as epilepsy. L-778123 binds to the Kv1.3 channel and inhibits its activity by blocking the flow of potassium ions through it. The binding site on L-778123 is completely different from that on other analogues that have been studied. This peptide can also be used to study protein interactions and antibody activity.

Formule : C₂₂H₂₂Cl₃N₅O

Degré de pureté : Min. 95%

Masse moléculaire : 478.8 g/mol

Ref: 3D-IHA49956