CAS 1863905-38-7

Formule : C25H28F4N2O6

InChI : InChI=1S/C25H28F4N2O6/c1-24(2,34)14-35-17-7-8-18(23(30)33)21(12-17)36-20-9-10-31(13-19(20)26)22(32)11-15-3-5-16(6-4-15)37-25(27,28)29/h3-8,12,19-20,34H,9-11,13-14H2,1-2H3,(H2,30,33)/t19-,20+/m1/s1

Code InChI : AUTGNDRENPBZKA-UXHICEINSA-N

SMILES : CC(C)(COC1=CC(=C(C=C1)C(=O)N)O[C@H]2CCN(C[C@H]2F)C(=O)CC3=CC=C(C=C3)OC(F)(F)F)O

PF-06737007

CAS : 1863905-38-7

PF-06737007

Formule : C₂₅H₂₈F₄N₂O₆

Degré de pureté : 99%

Masse moléculaire : 528.49

Ref: 54-PC1032645

PF-06737007

CAS : 1863905-38-7

PF-06737007 is an effective inhibitor of pan-Trk in cell-based assays (IC50s: 7.7 nM, 15 nM, and 3.9 nM for TrkA, TrkB, and TrkC, respectively).

Formule : C₂₅H₂₈F₄N₂O₆

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 528.49

Ref: TM-T17170

PF-06737007

CAS : 1863905-38-7

Formule : C₂₅H₂₈F₄N₂O₆

Degré de pureté : 99%

Masse moléculaire : 528.4932

Ref: IN-DA01V4O0

PF-06737007

CAS : 1863905-38-7

PF-06737007 is a small molecule inhibitor of the tyrosine kinase receptor, c-Met. It displays tumor growth inhibition in various human tumor cell lines and activates c-Met oncogenes. PF-06737007 also has anti-cancer effects by inhibiting the activation of molecules that are involved in tumorigenesis, such as the molecule MET. PF-06737007 may be a potential drug for cancer treatment.

Formule : C₂₅H₂₈F₄N₂O₆

Degré de pureté : Min. 95%

Masse moléculaire : 528.49 g/mol

Ref: 3D-NZC90538