CAS 1951408-58-4

Formule : C20H17FN6O

InChI : InChI=1S/C20H17FN6O/c1-12-13(3-2-7-22-12)16-10-24-20(27-11-25-26-19(16)27)23-9-15-14-6-8-28-18(14)5-4-17(15)21/h2-5,7,10-11H,6,8-9H2,1H3,(H,23,24)

Code InChI : XLIBABIFOBYHSV-UHFFFAOYSA-N

SMILES : CC1=C(C=CC=N1)C2=CN=C(N3C2=NN=C3)NCC4=C(C=CC5=C4CCO5)F

MAK683

CAS : 1951408-58-4

MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).

Formule : C₂₀H₁₇FN₆O

Degré de pureté : 98.43% - 99.92%

Couleur et forme : Solid

Masse moléculaire : 376.39

Ref: TM-T15201

MAK683

CAS : 1951408-58-4

MAK683

Formule : C₂₀H₁₇FN₆O

Degré de pureté : ≥98%

Masse moléculaire : 376.39

Ref: 54-BUP12500

MAK683

CAS : 1951408-58-4

N-((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-(2-methylpyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine

Formule : C₂₀H₁₇FN₆O

Degré de pureté : 99%

Masse moléculaire : 376.39

Ref: IN-DG00767212

MAK-683

CAS : 1951408-58-4

MAK-683 is a novel drug that inhibits protein lysine methylation. It is a Toll-like receptor modulator and structural biology agent that binds to the Toll-like receptor molecule and prevents it from binding to its target. MAK-683 has been shown to inhibit the activity of CDK4/6, which are enzymes that regulate the cell cycle. This drug also inhibits transcriptional regulation by interfering with the expression of inflammatory cytokines such as IL-1β, TNF-α, and IL-6. MAK-683 has been shown to be effective in treating cancer and chemoresistance, as well as inflammatory diseases like asthma.

Formule : C₂₀H₁₇FN₆O

Degré de pureté : Min. 95%

Masse moléculaire : 376.39 g/mol

Ref: 3D-BDD40858