CAS 2027476-29-3

Formule : C38H69N15O14

InChI : InChI=1S/C38H69N15O14/c1-17(2)12-22(51-34(65)24(16-54)52-35(66)28(39)18(3)4)32(63)49-20(8-6-10-44-37(40)41)30(61)46-14-25(56)48-23(13-26(57)58)33(64)53-29(19(5)55)36(67)50-21(9-7-11-45-38(42)43)31(62)47-15-27(59)60/h17-24,28-29,54-55H,6-16,39H2,1-5H3,(H,46,61)(H,47,62)(H,48,56)(H,49,63)(H,50,67)(H,51,65)(H,52,66)(H,53,64)(H,57,58)(H,59,60)(H4,40,41,44)(H4,42,43,45)/t19-,20+,21+,22+,23+,24+,28+,29+/m1/s1

Code InChI : PANKEFXOUZHWPR-UTRUBKBJSA-N

SMILES : C[C@H]([C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)N)O

VSLRGDTRG

CAS : 2027476-29-3

VSLRGDTRG is a synthetic peptide derived from the RGD motif in cadherin17 (CDH17) that binds to the α2β1 integrin, activating its signaling pathways. By promoting high-affinity conformational changes in β1 integrins through the RGD motif, VSLRGDTRG enhances cell adhesion and the phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. This peptide is useful for research on cancers expressing CDH17, such as colorectal and pancreatic cancer.

Formule : C₃₈H₆₉N₁₅O₁₄

Couleur et forme : Solid

Masse moléculaire : 960.047

Ref: TM-TP3241