CAS 2079895-42-2

Formule : C23H18N6O2S

InChI : InChI=1S/C23H18N6O2S/c24-32(30,31)19-11-9-18(10-12-19)27-23-28-20(21-22(29-23)26-14-25-21)17-8-4-7-16(13-17)15-5-2-1-3-6-15/h1-14H,(H2,24,30,31)(H2,25,26,27,28,29)

Code InChI : FUGRWXRQJGJIER-UHFFFAOYSA-N

SMILES : C1=CC=C(C=C1)C2=CC(=CC=C2)C3=C4C(=NC(=N3)NC5=CC=C(C=C5)S(=O)(=O)N)N=CN4

CDK2-IN-4

CAS : 2079895-42-2

CDK2-IN-4

Formule : C₂₃H₁₈N₆O₂S

Degré de pureté : ≥95%

Masse moléculaire : 442.49

Ref: 54-BUP04199

CDK2-IN-4

CAS : 2079895-42-2

CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.

Formule : C₂₃H₁₈N₆O₂S

Degré de pureté : 97.24% - 99.10%

Couleur et forme : Solid

Masse moléculaire : 442.49

Ref: TM-T14916

CDK2 inhibitor 73

CAS : 2079895-42-2

Formule : C₂₃H₁₈N₆O₂S

Degré de pureté : 98%

Masse moléculaire : 442.4930

Ref: IN-DA01V2O6

CDK2-IN-4

CAS : 2079895-42-2

4-((6-([1,1'-Biphenyl]-3-yl)-7H-purin-2-yl)amino)benzenesulfonamide

Formule : C₂₃H₁₈N₆O₂S

Degré de pureté : 98%

Masse moléculaire : 442.49

Ref: IN-DG01107055

CDK2-IN-4

CAS : 2079895-42-2

Degré de pureté : 98%

Masse moléculaire : 442.121

Ref: 10-F840857

CDK2-IN-4

CAS : 2079895-42-2

CDK2-IN-4 is a synthetic small molecule that inhibits the activity of kinases. It has been shown to inhibit the activity of CDK2, CDK4, and CDK6 in leukaemia cells. CDK2-IN-4 also inhibits the activity of kinases in other cancer cell lines. The synthesis of this compound was accomplished using a cross-coupling reaction between aryl boronic acid and aniline derivatives. This synthesis was pursued through kinetic studies involving alkylation reactions with 2-(3,5-dimethylpyrazol-1-yl)pyridinium bromide (DMPP). Kinetic parameters were determined by isothermal titration calorimetry (ITC).

Formule : C₂₃H₁₈N₆O₂S

Degré de pureté : Min. 95%

Masse moléculaire : 442.49 g/mol

Ref: 3D-EID89542