CAS 2101958-02-3

Formule : C25H32F3N5O4

InChI : InChI=1S/C25H32F3N5O4/c1-2-37-24(36)33-9-6-18(7-10-33)30-21-20(22(34)23(21)35)29-8-11-31-12-14-32(15-13-31)19-5-3-4-17(16-19)25(26,27)28/h3-5,16,18,29-30H,2,6-15H2,1H3

Code InChI : ZKITWOVRRSBKFG-UHFFFAOYSA-N

SMILES : CCOC(=O)N1CCC(CC1)NC2=C(C(=O)C2=O)NCCN3CCN(CC3)C4=CC=CC(=C4)C(F)(F)F

squarunkinA

CAS : 2101958-02-3

squarunkinA

Formule : C₂₅H₃₂F₃N₅O₄

Degré de pureté : ≥98%

Masse moléculaire : 523.55

Ref: 54-BUP06617

Ethyl 4-((3,4-dioxo-2-((2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)amino)cyclobut-1-en-1-yl)amino)piperidine-1-carboxylate

CAS : 2101958-02-3

Formule : C₂₅H₃₂F₃N₅O₄

Degré de pureté : 99%

Couleur et forme : Solid

Masse moléculaire : 523.5479

Ref: IN-DA01EQFW

squarunkinA

CAS : 2101958-02-3

squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-

Formule : C₂₅H₃₂F₃N₅O₄

Degré de pureté : 99.29%

Couleur et forme : White Solid

Masse moléculaire : 523.5479

Ref: TM-T9002

Squarunkin A

CAS : 2101958-02-3

Selective inhibitor of the interaction between the UNC119 chaperone and its cargo. Squarunkin A inhibits activation of Src kinase by interrupting the interaction between the myristoylated peptide at the N-terminus of the Src kinase and UNC119A chaperone (IC50 = 10 nM). Squarunkin A impairs the UNC119-mediated enrichment of plasma membrane with non-receptor protein tyrosine kinase Src, resulting in the decrease in Src autophosphorylation and decreased oncogenic Src signalling.

Formule : C₂₅H₃₂F₃N₅O₄

Degré de pureté : Min. 95%

Couleur et forme : Solid

Masse moléculaire : 523.55 g/mol

Ref: 3D-BS168651