CAS 2365497-07-8

Formule : C30H35F3N6O3

InChI : InChI=1S/C30H35F3N6O3/c1-41-27-17-23(38-15-12-34-13-16-38)6-9-26(27)37-28-18-24(10-11-35-28)39-14-2-3-22(20-39)29(40)36-19-21-4-7-25(8-5-21)42-30(31,32)33/h4-11,17-18,22,34H,2-3,12-16,19-20H2,1H3,(H,35,37)(H,36,40)/t22-/m0/s1

Code InChI : JQWJRFOFKDLCQB-QFIPXVFZSA-N

SMILES : COC1=C(C=CC(=C1)N2CCNCC2)NC3=NC=CC(=C3)N4CCC[C@@H](C4)C(=O)NCC5=CC=C(C=C5)OC(F)(F)F

ALK/ROS1-IN-1

CAS : 2365497-07-8

ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme).

Formule : C₃₀H₃₅F₃N₆O₃

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 584.63

Ref: TM-T10286