CAS 2366237-37-6

Formule : C25H31FN8

InChI : InChI=1S/C25H31FN8/c1-3-32-13-25(14-32)15-33(16-25)18-7-8-21(27-10-18)30-24-28-12-20(26)22(31-24)19-11-29-34-9-5-4-6-17(2)23(19)34/h7-8,10-12,17H,3-6,9,13-16H2,1-2H3,(H,27,28,30,31)/t17-/m1/s1

Code InChI : KMRYRPPWJDYHAL-QGZVFWFLSA-N

SMILES : CCN1CC2(C1)CN(C2)C3=CN=C(C=C3)NC4=NC=C(C(=N4)C5=C6[C@@H](CCCCN6N=C5)C)F

CDK4/6-IN-3

CAS : 2366237-37-6

CDK4/6-IN-3 is a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM) used for the treatment of glioblastoma. It inhibits CDK1 with a Ki of 110 nM.

Formule : C₂₅H₃₁FN₈

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 462.57

Ref: TM-T10737