CAS 28115-68-6

(-)-Pluviatolide

Formule : C₂₀H₂₀O₆

InChI : InChI=1S/C20H20O6/c1-23-18-8-13(2-4-16(18)21)7-15-14(10-24-20(15)22)6-12-3-5-17-19(9-12)26-11-25-17/h2-5,8-9,14-15,21H,6-7,10-11H2,1H3/t14-,15+/m0/s1

Code InChI : InChIKey=OCTZTNYFALPGHW-LSDHHAIUSA-N

SMILES : C([C@@H]1[C@@H](CC=2C=C3C(=CC2)OCO3)COC1=O)C4=CC(OC)=C(O)C=C4

Synonymes :

• 2(3H)-Furanone, dihydro-4-piperonyl-3-vanillyl-
• 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R-trans)-
• Pluviatolide
• (3R,4R)-4-(1,3-Benzodioxol-5-ylmethyl)dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone
• 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4R)-

(3R,4R)-4-(Benzo[d][1,3]dioxol-5-ylmethyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one

CAS : 28115-68-6

(3R,4R)-4-(Benzo[d][1,3]dioxol-5-ylmethyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one

Formule : C₂₀H₂₀O₆

Degré de pureté : ≥98%

Masse moléculaire : 356.37

Ref: 54-OR1106472

Pluviatolide

CAS : 28115-68-6

(-)-Pluviatolide can inhibit electrically-induced and acetylcholine-induced contraction in the isolated guinea-pig ileum.

Formule : C₂₀H₂₀O₆

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 356.37

Ref: TM-TN4812

Pluviatolide

CAS : 28115-68-6

Pluviatolide is a sesquiterpene lactone, which is a secondary metabolite derived from plants. Specifically, it is sourced from various species within the Asteraceae family. The mode of action of Pluviatolide involves the induction of apoptosis, a programmed cell death pathway. It achieves this by modulating key signaling pathways that regulate cell survival and apoptosis, including the NF-κB and MAPK pathways. This modulation leads to the activation of caspases and subsequent cell death in cancerous cells.

Formule : C₂₀H₂₀O₆

Degré de pureté : Min. 95%

Masse moléculaire : 356.4 g/mol

Ref: 3D-DBA11568