CAS 2941024-89-9

Formule : C24H26FN5O4

InChI : InChI=1S/C24H26FN5O4/c1-33-11-12-34-18-13-19(25)23-20(14-18)26-15-27-24(23)29-17-6-4-16(5-7-17)28-21(31)8-10-30-9-2-3-22(30)32/h4-7,13-15H,2-3,8-12H2,1H3,(H,28,31)(H,26,27,29)

Code InChI : XBEWPWNQUDCPAH-UHFFFAOYSA-N

SMILES : COCCOC1=CC2=C(C(=C1)F)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)CCN4CCCC4=O

c-Kit-IN-8

CAS : 2941024-89-9

C-Kit-IN-8 (Compound 53) acts as an inhibitor of c-Kit kinase, hampering uKIT kinase activity with an IC₅₀ greater than 1 μM. Additionally, it inhibits the proliferation of both wild-type and mutant GIST430 and BaF3 cancer cells, exhibiting an IC₅₀ greater than 0.1 μM.

Formule : C₂₄H₂₆FN₅O₄

Couleur et forme : Solid

Masse moléculaire : 467.49

Ref: TM-T200947