CAS 3038446-91-9

SK2187

CAS : 3038446-91-9

trans-4-(3-Chloro-2-fluorophenoxy)-N-(1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-2-oxo-6,9,12-trioxa-3-azatetradecan-14-yl)-1-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)cyclohexane-1-carboxamide

Degré de pureté : 95%

Ref: IN-DG02828480

SK2187

CAS : 3038446-91-9

SK2187 is a selective degrader of AURKAPROTAC with a DC50 of approximately 10 nM. It exhibits growth-inhibitory effects on NGP cells, with an IC50 value of 101.5 nM. SK2187 is utilized in studies of MYCN-amplified neuroblastoma.

Formule : C₄₅H₄₉ClFN₇O₁₁S

Couleur et forme : Solid

Masse moléculaire : 950.43

Ref: TM-T211420