CAS 3047242-55-4

Cyclopropanecarboxamide, 3-[4-[(8R)-2-chloro-7,8-dihydro-8-methyl-8-(trifluoromethyl)-6H-pyrazolo[1,5-a]pyrrolo[2,3-e]pyrimidin-6-yl]phenyl]-2,2-difluoro-1-methyl-N-[trans-3-(methylsulfonyl)cyclobutyl]-, (1R,3S)-

Formule : C₂₆H₂₅ClF₅N₅O₃S

InChI : InChI=1S/C26H25ClF5N5O3S/c1-23(26(30,31)32)12-36(17-11-33-19-10-18(27)35-37(19)21(17)23)15-6-4-13(5-7-15)20-24(2,25(20,28)29)22(38)34-14-8-16(9-14)41(3,39)40/h4-7,10-11,14,16,20H,8-9,12H2,1-3H3,(H,34,38)/t14?,16?,20-,23+,24+/m0/s1

Code InChI : ZNAJYCIMHPYJAW-CQPNCCEXSA-N

SMILES : C[C@]1(CN(C2=C1N3C(=CC(=N3)Cl)N=C2)C4=CC=C(C=C4)[C@H]5[C@](C5(F)F)(C)C(=O)NC6CC(C6)S(=O)(=O)C)C(F)(F)F

Synonymes :

• Cyclopropanecarboxamide, 3-[4-[(8R)-2-chloro-7,8-dihydro-8-methyl-8-(trifluoromethyl)-6H-pyrazolo[1,5-a]pyrrolo[2,3-e]pyrimidin-6-yl]phenyl]-2,2-difluoro-1-methyl-N-[trans-3-(methylsulfonyl)cyclobutyl]-, (1R,3S)-

MALT1-IN-14

CAS : 3047242-55-4

MALT1-IN-14

Formule : C₂₆H₂₅ClF₅N₅O₃S

Degré de pureté : ≥95%

Masse moléculaire : 618.02

Ref: 54-PC1034019

MALT1-IN-14

CAS : 3047242-55-4

MALT1-IN-14 (comp 2) is a potent and selective MALT1 inhibitor with an IC50 value of 0.081 μM, widely utilized in immunology and oncology research to suppress MALT1 protease activity, dissect NF-κB signaling cascades, and evaluate therapeutic approaches targeting lymphoid malignancies and inflammatory diseases driven by dysregulated immune activation.

Formule : C₂₆H₂₅ClF₅N₅O₃S

Couleur et forme : Solid

Masse moléculaire : 618.02

Ref: TM-T200726