CAS 3108318-77-7

JAK2-IN-18

CAS : 3108318-77-7

JAK2-IN-18 (Compound example1) is a selective JAK2 inhibitor. It effectively inhibits the JAK-STAT signaling pathway, with an IC50 value of less than 100 nM for pSTAT5 in HEL9217 cells. JAK2-IN-18 suppresses the proliferation of abnormally proliferating myeloid cells and is useful in research on myeloproliferative disorders, such as essential thrombocythemia.

Formule : C₃₇H₃₆N₈O₄

Masse moléculaire : 656.75

Ref: TM-T214358