CAS 3110703-72-2

TYD-68

CAS : 3110703-72-2

TYD-68 is a potent and selective CRBN-recruiting TYK2 PROTAC degrader, with a DC₅₀ value of 0.42 nM. This compound effectively inhibits IL-12 and IFN-α-induced phosphorylation of STAT4 and STAT1, thereby blocking TYK2-dependent signaling pathways. TYD-68 is applicable in psoriasis research.

Formule : C₄₃H₄₀FN₁₁O₇

Couleur et forme : Odour Solid

Masse moléculaire : 841.85

Ref: TM-T206972