CAS 327613-57-0

Acide 2(S)-[1-(3,5-dichlorophénylsulfonyl)-L-prolylamino]-4-[N-méthyl-N-[2-[4-[3-(2-méthylphényl)uréido]phényl]acétyl]-L-leucylamino]butyrique

Formule : C₃₈H₄₆Cl₂N₆O₈S

InChI : InChI=1S/C38H46Cl2N6O8S/c1-23(2)18-33(45(4)34(47)19-25-11-13-28(14-12-25)42-38(52)44-30-9-6-5-8-24(30)3)35(48)41-16-15-31(37(50)51)43-36(49)32-10-7-17-46(32)55(53,54)29-21-26(39)20-27(40)22-29/h5-6,8-9,11-14,20-23,31-33H,7,10,15-19H2,1-4H3,(H,41,48)(H,43,49)(H,50,51)(H2,42,44,52)/t31-,32-,33-/m0/s1

Code InChI : MNQBPRHHZPXCKZ-ZDCRTTOTSA-N

SMILES : CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)CC(=O)N(C)[C@@H](CC(C)C)C(=O)NCC[C@@H](C(=O)O)NC(=O)[C@@H]3CCCN3S(=O)(=O)C4=CC(=CC(=C4)Cl)Cl

Synonymes :

• Bio-5192
• (BIO5192)
• (2(S)-[1-(3,5-Dichlorophenylsulfonyl)-L-prolylaMino]-4-[N-Methyl-N-[2-[4-[3-(2-Methylphenyl)ureido]phenyl]acetyl]-L-leucylaMino]butyric acid )
• Butanoic acid, 2-[[[(2S)-1-[(3,5-dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]-, (2S)-
• (2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]butanoic acid
• (S)-2-((S)-1-((3,5-dichlorophenyl)sulfonyl)pyrrolidine-2-carboxamido)-4-((S)-4-methyl-2-(N-methyl-2-(4-(3-(o-tolyl)ureido)phenyl)acetamido)pentanamido)butanoic acid
• AMD 15057

Amd 15057

CAS : 327613-57-0

Amd 15057

Formule : C₃₈H₄₆Cl₂N₆O₈S

Degré de pureté : ≥95%

Masse moléculaire : 817.78

Ref: 54-OR1103746

BIO 5192

CAS : 327613-57-0

BIO 5192 is a high-affinity α4β1 (VLA-4) antagonist that mimics the VCAM-1 epitope to block cell adhesion for inflammation and autoimmune disease research.

Formule : C₃₈H₄₆Cl₂N₆O₈S

Masse moléculaire : 817.78

Ref: TM-T21682

(2(S)-[1-(3,5-Dichlorophenylsulfonyl)-L-prolylaMino]-4-[N-Methyl-N-[2-[4-[3-(2-Methylphenyl)ureido]phenyl]acetyl]-L-leucylaMino]butyric acid )

CAS : 327613-57-0

Formule : C₃₈H₄₆Cl₂N₆O₈S

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 817.7782

Ref: IN-DA00CAYX

BIO 5192

CAS : 327613-57-0

BIO 5192 is a receptor-binding molecule that may be used to treat autoimmune diseases and blood disorders, such as hemolytic anemia. It binds to the CD81 receptor on cells, which prevents the binding of inhibitory molecules and blocks the activation of T cells. BIO 5192 has been shown to have no long-term toxicity in mice and does not cause any weight loss or organ damage in these animals. It has also been shown to stimulate hematopoietic cells (cells that produce blood) in vitro. BIO 5192 is currently being investigated for its potential use in treating inflammatory diseases such as rheumatoid arthritis.

Formule : C₃₈H₄₆Cl₂N₆O₈S

Degré de pureté : Min. 95%

Masse moléculaire : 817.78 g/mol

Ref: 3D-CNA61357