CAS 332164-34-8

HFI-142

CAS : 332164-34-8

HFI-142 is a inhibitor to aminopeptidase N; inhibit leukotriene A4 biosynthesis in red blood cells; inhibit dditional aminopeptidases.

Formule : C₁₇H₁₆N₂O₄

Couleur et forme : Solid

Masse moléculaire : 312.32

Ref: TM-T15479

Ethyl 2-amino-7-hydroxy-4-(pyridin-3-yl)-4H-chromene-3-carboxylate

CAS : 332164-34-8

Degré de pureté : 95.0%

Masse moléculaire : 312.32501220703125

Ref: 10-F494678

Ethyl 2-Amino-7-hydroxy-4-(pyridin-3-yl)-4H-chromene-3-carboxylate

Produit contrôlé

CAS : 332164-34-8

Applications Ethyl 2-Amino-7-hydroxy-4-(pyridin-3-yl)-4H-chromene-3-carboxylate acts as a reagent in the synthesis, structural-activity relationship and the brain uptake of benzopyran inhibitors of insulin regulated aminopeptidase.
References Mountford, Simon J., et al.: J. Med. Chem., 57, 1368 (2014)

Formule : C₁₇H₁₆N₂O₄

Couleur et forme : Neat

Masse moléculaire : 312.32

Ref: TR-E677505

HFI-142

CAS : 332164-34-8

HFI-142 is a small molecule that binds to the active site of aminopeptidase N and inhibits its activity. This drug has been shown to inhibit leukotriene A4 biosynthesis in red blood cells, which may be useful for the treatment of cancer. HFI-142 was also found to inhibit the activity of other aminopeptidases, such as aminopeptidase N, as well as other enzymes involved in protein metabolism. The drug showed no mutagenicity in a wide range of assays, including bacterial mutagenicity tests, chromosomal aberration tests with human lymphocytes, and Ames tests.

Formule : C₁₇H₁₆N₂O₄

Degré de pureté : Min. 95%

Masse moléculaire : 312.32 g/mol

Ref: 3D-HNA16434