CAS 332164-34-8

Formule : C17H16N2O4

InChI : InChI=1S/C17H16N2O4/c1-2-22-17(21)15-14(10-4-3-7-19-9-10)12-6-5-11(20)8-13(12)23-16(15)18/h3-9,14,20H,2,18H2,1H3

Code InChI : JOPNHSIHFSZJMB-UHFFFAOYSA-N

SMILES : CCOC(=O)C1=C(OC2=C(C1C3=CN=CC=C3)C=CC(=C2)O)N

HFI-142

CAS : 332164-34-8

HFI-142

Formule : C₁₇H₁₆N₂O₄

Degré de pureté : 10 mM in DMSO

Masse moléculaire : 312.32

Ref: 54-BUP22405

HFI-142

CAS : 332164-34-8

HFI-142 is a inhibitor to aminopeptidase N; inhibit leukotriene A4 biosynthesis in red blood cells; inhibit dditional aminopeptidases.

Formule : C₁₇H₁₆N₂O₄

Couleur et forme : White Solid

Masse moléculaire : 312.3199

Ref: TM-T15479

Ethyl 2-amino-7-hydroxy-4-(pyridin-3-yl)-4H-chromene-3-carboxylate

CAS : 332164-34-8

Degré de pureté : 95.0%

Masse moléculaire : 312.32501220703125

Ref: 10-F494678

Ethyl 2-Amino-7-hydroxy-4-(pyridin-3-yl)-4H-chromene-3-carboxylate

Produit contrôlé

CAS : 332164-34-8

Applications Ethyl 2-Amino-7-hydroxy-4-(pyridin-3-yl)-4H-chromene-3-carboxylate acts as a reagent in the synthesis, structural-activity relationship and the brain uptake of benzopyran inhibitors of insulin regulated aminopeptidase.
References Mountford, Simon J., et al.: J. Med. Chem., 57, 1368 (2014)

Formule : C₁₇H₁₆N₂O₄

Couleur et forme : Neat

Masse moléculaire : 312.32

Ref: TR-E677505

HFI-142

CAS : 332164-34-8

HFI-142 is a small molecule that binds to the active site of aminopeptidase N and inhibits its activity. This drug has been shown to inhibit leukotriene A4 biosynthesis in red blood cells, which may be useful for the treatment of cancer. HFI-142 was also found to inhibit the activity of other aminopeptidases, such as aminopeptidase N, as well as other enzymes involved in protein metabolism. The drug showed no mutagenicity in a wide range of assays, including bacterial mutagenicity tests, chromosomal aberration tests with human lymphocytes, and Ames tests.

Formule : C₁₇H₁₆N₂O₄

Degré de pureté : Min. 95%

Masse moléculaire : 312.32 g/mol

Ref: 3D-HNA16434