CAS 39562-70-4
:Nitrendipine
Description :
Nitrendipine est un bloqueur des canaux calciques principalement utilisé dans le traitement de l'hypertension et de l'angine de poitrine. Il appartient à la classe des composés dihydropyridiniques, qui se caractérisent par leur capacité à inhiber sélectivement l'afflux de calcium à travers les canaux calciques de type L dans le muscle lisse vasculaire et le tissu cardiaque. Cette action entraîne une vasodilatation et une diminution subséquente de la pression artérielle. Nitrendipine est connu pour sa haute lipophilie, ce qui améliore son absorption et sa distribution dans le corps. Le composé présente généralement une longue demi-vie, permettant une posologie une fois par jour dans les milieux cliniques. Sa structure chimique comprend un groupe nitro, qui contribue à ses propriétés pharmacologiques. Nitrendipine est généralement bien toléré, mais comme d'autres bloqueurs des canaux calciques, il peut provoquer des effets secondaires tels que des maux de tête, des bouffées de chaleur ou un œdème périphérique. Comme pour tout médicament, il est important de prendre en compte les contre-indications et les interactions potentielles avec d'autres médicaments. Dans l'ensemble, Nitrendipine est un agent efficace dans la gestion des conditions cardiovasculaires, contribuant à améliorer les résultats des patients.
Formule :C18H20N2O6
InChI :InChI=1/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,15-16H,5H2,1-4H3/t15?,16-/m1/s1
Code InChI :InChIKey=PVHUJELLJLJGLN-UHFFFAOYSA-N
SMILES :C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1C)C2=CC(N(=O)=O)=CC=C2
Synonymes :- (.+-.)-Bay E 5009
- (.+-.)-Nitrendipine
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-ethyl 5-methyl ester
- Baylotensin
- Bayotensin
- Baypress
- Bylotensin
- Cardif
- Deiten
- Nidrel
- Nitrendipin
- Nitrendipino
- Nitrepin
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester
- 3-ethyl 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate
- 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester
- 3-ethyl 5-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate
- ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(meta-nitrophenyl)-3,5-pyridinedicarboxylate
- NITRENDIPINE IMPURITY AETHYL METHYL-2,6-DIMETHYL-4-(3-NITROPHENYL) PYRIDINE-3,5-DICARBOXYLATE
- ylmethylester
- NITRENDIPINE EPN(CRM STANDARD)
- (NITROPHENYLPYRIDINE ANALOGUE) EPN(CRM STANDARD)
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester (9CI)
- NITRENDIPINE >95% CA2+ CHANNEL BLOCKER,
- ethylmethyl1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxy
- 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacidethy
- NITRENDIPINE MM(CRM STANDARD)
- baye5009
- Voir plus de synonymes
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Nitrendipine
CAS :Formule :C18H20N2O6Degré de pureté :>98.0%(HPLC)(N)Couleur et forme :White to Yellow powder to crystalMasse moléculaire :360.37Nitrendipine
CAS :L-type calcium channel blockerFormule :C18H20N2O6Couleur et forme :PowderMasse moléculaire :360.37NITRENDIPINE FOR PEAK IDENTIFICATION CRS
CAS :NITRENDIPINE FOR PEAK IDENTIFICATION CRSFormule :C18H20N2O6Masse moléculaire :360.3612Nitrendipine
CAS :Formule :C18H20N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.3612Nitrendipine
CAS :3-Ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylateFormule :C18H20N2O6Degré de pureté :98%Masse moléculaire :360.36Nitrendipine
CAS :Nitrendipine is a vasodilating calcium channel blocker and antihypertensive that preserves kidney function and promotes sodium excretion.Formule :C18H20N2O6Degré de pureté :99% - 99.55%Couleur et forme :SolidMasse moléculaire :360.36Ref: TM-T0119
10mg35,00€25mg52,00€1mL*10mM (DMSO)52,00€50mg67,00€100mg113,00€200mg172,00€500mg268,00€1g414,00€Nitrendipine
CAS :Formule :C18H20N2O6Degré de pureté :≥ 97.0%Couleur et forme :Pale yellow to yellow or green powderMasse moléculaire :360.36Nitrendipine 100 µg/mL in Acetonitrile
CAS :Formule :C18H20N2O6Couleur et forme :Single SolutionMasse moléculaire :360.36Nitrendipine (Standard)
CAS :Nitrendipine (Standard) is the standard substance of Nitrendipine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nitrendipine (BAY-E-5009) is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.Formule :C18H20N2O6Masse moléculaire :360.36Nitrendipine-d5
CAS :Produit contrôléApplications Nitrendipine-d5 is the isotope labelled analogue of Nitrendipine (N490150), a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.
References Ventura, H.O., et al.: Am. J. Cardiol., 51, 783 (1983),Formule :C18H15D5N2O6Couleur et forme :NeatMasse moléculaire :365.39Nitrendipine
CAS :Produit contrôléApplications Nitrendipine is a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.
References Ventura, H.O., et al.: Am. J. Cardiol., 51, 783 (1983); Kann, J. et al.: Brit. J. Clin. Pharmacol., 33, 51 (1992);Formule :C18H20N2O6Couleur et forme :NeatMasse moléculaire :360.36(RS)-Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
CAS :Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is a propranolol hydrochloride derivative that has vasodilatory effects. It is used as a nitrovasodilator to treat angina pectoris and high blood pressure. Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate binds to the alpha1 adrenergic receptors in the heart and causes vasodilation by inhibiting the release of norepinephrine from sympathetic nerves. This drug also inhibits the binding of norepinephrine to cardiac beta receptors which decreases the heart rate and contractility of cardiac muscle. Methyl ethyl 1,4-dihydro-2,6Formule :C18H20N2O6Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :360.36 g/mol(RS)-Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate - EP Grade
CAS :Propranolol hydrochloride is a non-selective beta-adrenergic blocker that blocks the effects of epinephrine, norepinephrine and dopamine. Propranolol hydrochloride has been shown to inhibit the activity of proximal tubules in the kidney, which may be due to its inhibition of chemical ionization. This drug also has antihypertensive activity and can be used for the treatment of cardiac disorders such as hypertension. Propranolol hydrochloride is a monoclonal antibody that is activated by nitro groups and binds with high affinity to multiple-reaction monitoring (MRM) transitions for protonated molecular ions at m/z 289, 296, 305, 313, 320, 328, 336 and 344. Propranolol hydrochloride also has vasodilatory effects on the papillary muscle which aids in regulating blood pressure by maintaining vascular resistance.Formule :C18H20N2O6Degré de pureté :Min. 95%Masse moléculaire :360.36 g/mol
