CAS 51166-71-3

Di-O-méthyl-β-cyclodextrine

Description :

Di-O-méthyl-β-cyclodextrine est un dérivé modifié de la β-cyclodextrine, qui est un oligosaccharide cyclique composé de sept unités de glucose. Ce composé présente deux groupes méthoxy attachés aux positions hydroxyles des unités de glucose, améliorant sa solubilité dans les solvants organiques et sa capacité à former des complexes d'inclusion avec diverses molécules invitées. Di-O-méthyl-β-cyclodextrine présente des caractéristiques telles qu'une lipophilie accrue par rapport à la β-cyclodextrine native, ce qui le rend utile dans les applications pharmaceutiques pour la délivrance et la stabilisation des médicaments. Il a un profil de toxicité relativement faible et est généralement reconnu comme sûr pour une utilisation dans les formulations alimentaires et pharmaceutiques. La capacité du composé à encapsuler des composés hydrophobes permet une meilleure biodisponibilité et un relâchement contrôlé des ingrédients actifs. De plus, il peut améliorer la stabilité des composés sensibles contre la dégradation. Ses applications s'étendent à des domaines tels que les cosmétiques, la science alimentaire et la dépollution environnementale, où il peut aider à la solubilisation et à la délivrance de diverses substances.

Formule : C₅₆H₉₈O₃₅

InChI : InChI=1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3/t22-,23-,24-,25-,26-,27-,28-,29+,30+,31+,32+,33+,34+,35+,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-/m1/s1

Code InChI : InChIKey=QGKBSGBYSPTPKJ-UZMKXNTCSA-N

SMILES : C(OC)[C@@H]1[C@@]2([C@H](O)[C@@H](OC)[C@](O1)(O[C@@]3([C@@H](COC)O[C@@]([C@H](OC)[C@H]3O)(O[C@@]4([C@@H](COC)O[C@@]([C@H](OC)[C@H]4O)(O[C@@]5([C@@H](COC)O[C@](O[C@]6([C@H](O)[C@@H](OC)[C@@](O[C@]7([C@H](O)[C@@H](OC)[C@@](O[C@]8([C@H](O)[C@@H](OC)[C@@](O2)(O[C@@H]8COC)[H])[H])(O[C@@H]7COC)[H])[H])(O[C@@H]6COC)[H])[H])([C@H](OC)[C@H]5O)[H])[H])[H])[H])[H])[H])[H])[H]

Synonymes :

• 2,4,7,9,12,14,17,19,22,24,27,29,32,34-Tetradecaoxaoctacyclo[31.2.2.2^3,6.2^8,11.2^13,16.2^18,21.2^23,26.2^28,31]nonatetracontane, β-cyclodextrin deriv.
• 2,6-2-Methyl-Beta-Cyclodextrin
• 2,6-Di-O-Methyl-Beta-Cyclodextrin
• 2,6-Di-O-methyl-β-cyclodextrin
• 2,6-Dimethyl-β-cyclodextrin
• 2^A,2^B,2^C,2^D,2^E,2^F,2^G,6^A,6^B,6^C,6^D,6^E,6^F,6^G-Tetradeca-O-methyl-β-cyclodextrin
• 2^A,6^A-Di-O-methyl-β-cyclodextrin
• Beta W 7M1.8
• Di-O-methyl-β-cyclodextrin
• Dimeb
• Dimeb 50
• Dimethyl-β-cyclodextrin
• Hepta-(2,6-di-oxy-methyl)-β-cyclodextrin
• Heptakis(2,6-di-O-methyl)-β-cyclodextrin
• Tetradeca-O-methyl-β-cyclodextrin
• Tetradecakis-2,6-O-methylcycloheptaamylose
• β-Cyclodextrin, 2^A,2^B,2^C,2^D,2^E,2^F,2^G,6^A,6^B,6^C,6^D,6^E,6^F,6^G-tetradeca-O-methyl-
• β-Cyclodextrin, 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-tetradeca-O-methyl-
• 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-Tetradeca-O-methyl-β-cyclodextrin

2,6-Di-O-methyl-beta-cyclodextrin

CAS : 51166-71-3

Formule : C₅₆H₉₈O₃₅

Degré de pureté : >95.0%(HPLC)

Couleur et forme : White to Light yellow powder to crystal

Masse moléculaire : 1,331.37

Ref: 3B-D5992

Heptakis(2,6-di-O-methyl)-β-cyclodextrin content > 35% (DS~14)

CAS : 51166-71-3

Heptakis(2,6-di-O-methyl)-β-cyclodextrin content > 35% (DS~14)

Formule : C₅₆H₉₈O₃₅

Degré de pureté : 95%

Couleur et forme : Solid-Powder

Masse moléculaire : 1331.35631

Ref: 54-BICY1000

Heptakis(2,6-di-O-methyl)-b-cyclodextrin

CAS : 51166-71-3

Formule : C₅₆H₉₈O₃₅

Degré de pureté : ≥ 98% (2,6-Di-O-methyl-b-CD + other methyl CDs)

Couleur et forme : White to off-white powder

Masse moléculaire : 1331.36

Ref: 7W-GC9584

β-Cyclodextrin, 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-tetradeca-O-methyl-

CAS : 51166-71-3

Formule : C₅₆H₉₈O₃₅

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 1331.3563

Ref: IN-DA00I95Q

DM-β-CD

CAS : 51166-71-3

DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule composed of seven glucose units, modified with two methyl groups at the 2 and 6 positions. It is commonly utilized as a solubilizer and carrier for poorly soluble drugs in pharmaceutical formulations. Additionally, its ability to form inclusion complexes with various guest molecules—such as aromatic compounds, pesticides, and heavy metals—makes it valuable in analytical chemistry, food science, and environmental remediation.

Formule : C₅₆H₉₈O₃₅

Masse moléculaire : 1331.3563

Ref: TM-TSH-00009

Di-O-methyl-b-cyclodextrin (90%)

Produit contrôlé

CAS : 51166-71-3

Applications Induces the release of cholesterol from cholesterol-rich lipid rafts located on the surface of cells, making it a good agent for removing cholesterol from processed foods
References Krajian, H., et al.: Anal. Bioanal. Chem., 394, 2193 (2009), Perez-Cruz, F., et al.: Bioorg. Med. Chem., 17, 4604 (2009), Motoyama, K., et al.: Biol. Pharm. Bull., 32, 700 (2009), Padula, C., et al.: Int. J. Pharm., 372, 12 (2009), Chen, Z., et al.: J. Pharm. Sci., 98, 229 (2009),

Formule : C₅₆H₉₈O₃₅

Degré de pureté : 90%

Couleur et forme : Neat

Masse moléculaire : 1331.36

Ref: TR-D470870

2,6-Dimethyl-b-cyclodextrin - Technical

CAS : 51166-71-3

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Formule : C₅₆H₉₈O₃₅

Degré de pureté : Min. 98%

Couleur et forme : White Powder

Masse moléculaire : 1,331.36 g/mol

Ref: 3D-OD08100

2,6-Dimethyl-beta-cyclodextrin

CAS : 51166-71-3

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Formule : C₅₆H₉₈O₃₅

Degré de pureté : Min. 98%

Couleur et forme : White Powder

Masse moléculaire : 1,331.36 g/mol

Ref: 3D-OD29274

2,6-Di-O-methyl-β-cyclodextrin

CAS : 51166-71-3

2,6-Di-O-methyl-β-cyclodextrin

Formule : C₅₆H₉₈O₃₅

Degré de pureté : 98%

Masse moléculaire : 1331.36

Ref: IN-DG297838

2,6-DI-O-METHYL-β-CYCLODEXTRIN

CAS : 51166-71-3

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 1331.36499

Ref: 10-F813397