CAS 73030-71-4
:Atractylénolide III
Description :
Atractylénolide III est un composé bioactif principalement dérivé des racines de l'herbe médicinale chinoise traditionnelle Atractylodes macrocephala. Il appartient à la classe des sesquiterpènes et se caractérise par sa structure chimique unique, qui contribue à ses diverses propriétés pharmacologiques. Ce composé est connu pour ses effets anti-inflammatoires, anticancéreux et immunomodulateurs potentiels, ce qui le rend intéressant tant en médecine traditionnelle qu'en recherche pharmacologique moderne. Atractylénolide III présente une gamme d'activités biologiques, y compris la capacité d'inhiber certaines enzymes et de moduler des voies de signalisation, ce qui peut contribuer à ses effets thérapeutiques. De plus, il a été étudié pour ses effets protecteurs contre le stress oxydatif et son rôle dans l'amélioration des réponses immunitaires. Le composé est généralement extrait et purifié à des fins de recherche, et son profil de sécurité est généralement considéré comme favorable, bien que d'autres études soient nécessaires pour comprendre pleinement ses mécanismes d'action et ses applications potentielles dans des contextes cliniques.
Formule :C15H20O3
InChI :InChI=1/C15H20O3/c1-9-5-4-6-14(3)8-15(17)12(7-11(9)14)10(2)13(16)18-15/h11,17H,1,4-8H2,2-3H3/t11-,14+,15-/m0/s1
Code InChI :InChIKey=FBMORZZOJSDNRQ-GLQYFDAESA-N
SMILES :O[C@@]12C(C[C@@]3([C@@](C)(C1)CCCC3=C)[H])=C(C)C(=O)O2
Synonymes :- (4aS,8aR,9aS)-4a,5,6,7,8,8a,9,9a-Octahydro-9a-hydroxy-3,8a-dimethyl-5-methylenenaphtho[2,3-b]furan-2(4H)-one
- (4aS,8aR,9aS)-9a-hydroxy-3,8a-dimethyl-5-methylidene-4a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(4H)-one
- 8β-Hydroxyasterolide
- Atractylenolide III
- Atractylenolide β
- Codonolactone
- Naphtho(2,3-b)furan-2(4H)-one, 4a,5,6,7,8,8a,9,9a-octahydro-9a-hydroxy-3,8a-dimethyl-5-methylene-, (4aS,8aR,9aS)-
- Naphtho[2,3-b]furan-2(4H)-one, 4a,5,6,7,8,8a,9,9a-octahydro-9a-hydroxy-3,8a-dimethyl-5-methylene-, [4aS-(4aα,8aβ,9aβ)]-
- Atractylenolide III, BR
- (4aS,8aR,9aS)-9a-Hydroxy-3,8a-dimethyl-5-methylidene-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzoxol-2-one
- Atractylenolide beta
- 8-HYDROXYASTEROLIDE
- ICodonolactone
- Atracylenolide III
- ATRACTYLENOLIDE
- (4aS)-4a,5,6,7,8,8a,9,9a-Octahydro-9aβ-hydroxy-3,8aβ-dimethyl-5-methylenenaphtho[2,3-b]furan-2(4H)-one
- Atractylenolide III (ICodonolactone
- Atractylenolide III USP/EP/BP
- Voir plus de synonymes
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Atractylenolide III
CAS :Formule :C15H20O3Degré de pureté :>98.0%(HPLC)(T)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :248.32Atractylenolide III
CAS :Atractylenolide IIIFormule :C15H20O3Degré de pureté :99.5%Masse moléculaire :248.32Atractylenolide III (Standard)
CAS :Atractylenolide III (Standard) is a reference standard for research and analysis in studies involving Atractylenolide III. Atractylenolide III (ICodonolactone) may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury. Atractylenolide III is a potential candidate for the treatment of human lung carcinoma by inducing the release of cytochrome c, upregulating the expression of Bax and translocating apoptosis-inducing factor.Formule :C15H20O3Masse moléculaire :248.3175Atractylenolide III
CAS :Atractylenolide III is the major bioactive component of Atractylodes lancea, it inhibits histamine release, suppresses activation of p38 mitogen-activated protein kinase, C-Jun-N-terminal protein kinase, and nuclear factor-κB in stimulated HMC-1 cells, and suppresses the activation of caspase-1 and the expression of receptor interacting protein-2, suggests that atractylenolide III may control immunological reactions by regulating the cellular functions of IL-6 in mast cells.Formule :C15H20O3Degré de pureté :95%~99%Couleur et forme :White cryst.Masse moléculaire :248.322(4aS,8aR,9aS)-9a-Hydroxy-3,8a-dimethyl-5-methylene-4a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(4H)-one
CAS :(4aS,8aR,9aS)-9a-Hydroxy-3,8a-dimethyl-5-methylene-4a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(4H)-oneFormule :C15H20O3Degré de pureté :98%Masse moléculaire :248.32Atractylenolide III
CAS :Atractylenolide III could treat cognitive issues and lung cancer by modulating apoptosis factors.Formule :C15H20O3Degré de pureté :99.63% - 99.98%Couleur et forme :SolidMasse moléculaire :248.3175Atractylenolide III
CAS :LactoneFormule :C15H20O3Degré de pureté :≥ 98.0 % (HPLC)Couleur et forme :PowderMasse moléculaire :248.32AtractylenolideIII
CAS :Atractylenolide III is a sesquiterpene lactone, which is derived from the rhizomes of Atractylodes macrocephala, a plant commonly used in traditional Chinese medicine. With its origin in botanical sources, the compound is notable for its diverse biological activities and mechanisms of action. Atractylenolide III exerts its effects primarily through the modulation of various signaling pathways, including anti-inflammatory, anti-cancer, and immunomodulatory pathways. It inhibits the production of pro-inflammatory cytokines and regulates the expression of key signaling proteins, thus impacting cellular processes such as proliferation, apoptosis, and differentiation. The compound shows promise in the treatment of conditions like cancer, inflammation, and immune disorders. Researchers continue to explore its potential benefits, seeking to elucidate the molecular mechanisms underlying its therapeutic effects and to optimize its application in various biomedical fields.Degré de pureté :Min. 95%Naphtho[2,3-b]furan-2(4H)-one,4a,5,6,7,8,8a,9,9a-octahydro-9a-hydroxy-3,8a-dimethyl-5-methylene-,(4aS,8aR,9aS)-
CAS :Formule :C15H20O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.3175
![Naphtho[2,3-b]furan-2(4H)-one,4a,5,6,7,8,8a,9,9a-octahydro-9a-hydroxy-3,8a-dimethyl-5-methylene-,(…](https://static.cymitquimica.com/products/IN/thumb/DA00ICC9.jpg)