CAS 813425-83-1

(3aS)-2-[(3S)-1-oxydoquinuclidinium-3-yl]-3a,4,5,6-tétrahydro-3H-benzo[de]isoquinolin-1-one

Formule : C₁₉H₂₄N₂O₂

InChI : InChI=1/C19H24N2O2/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-20(19)17-12-21(23)9-7-13(17)8-10-21/h2,4,6,13,15,17H,1,3,5,7-12H2/t13?,15-,17-,21?/m1/s1

Code InChI : IQQIWUDYGYXXEA-BGAFOXLKSA-N

SMILES : C1Cc2cccc3c2[C@H](C1)CN([C@@H]1CN2(=O)CCC1CC2)C3=O

Synonymes :

• Palonosetron N-Oxide

Palonosetron Related Compound A

CAS : 813425-83-1

Lactams not elsewhere specified or included

Formule : C₁₉H₂₄N₂O₂

Couleur et forme : White Solid

Masse moléculaire : 312.18378

Ref: 45-1492222

Palonosetron N-oxide

CAS : 813425-83-1

Palonosetron N-oxide

Formule : C₁₉H₂₄N₂O₂

Degré de pureté : 98%

Masse moléculaire : 312.41

Ref: 54-OR1037291

Palonosetron N-oxide

CAS : 813425-83-1

Palonosetron N-oxide: metabolite and potential impurity of 5-HT3 antagonist palonosetron; forms under oxidative stress.

Formule : C₁₉H₂₄N₂O₂

Couleur et forme : Solid

Masse moléculaire : 312.413

Ref: TM-T37246

Palonosetron EP Impurity H (Palonosetron USP Related Compound A, Palonosetron N-Oxide)

CAS : 813425-83-1

Formule : C₁₉H₂₄N₂O₂

Couleur et forme : White To Off-White Solid

Masse moléculaire : 312.41

Ref: 4Z-P-533

1H-Benz[de]isoquinolin-1-one, 2,3,3a,4,5,6-hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-, (3aS)-

CAS : 813425-83-1

Formule : C₁₉H₂₄N₂O₂

Degré de pureté : 95%

Couleur et forme : Solid

Masse moléculaire : 312.4061

Ref: IN-DA0059QT

Palonosetron N-Oxide

Produit contrôlé

CAS : 813425-83-1

Applications A metabolite of Palonosetron (P165800).
References Stoltz, R., et al.: Biopharm., Drug Disposition, 25, 329 (2004), Stoltz, R., et al.: J. Clin. Pharmacol., 44, 520 (2004),

Formule : C₁₉H₂₄N₂O₂

Degré de pureté : >90%

Couleur et forme : Neat

Masse moléculaire : 312.41

Ref: TR-P165815

Palonosetron USP Related Compound A

CAS : 813425-83-1

Formule : C₁₉H₂₄N₂O₂

Masse moléculaire : 312.41

Ref: ST-EA-CP-P14001

Palonosetron N-oxide

CAS : 813425-83-1

Formule : C₁₉H₂₄N₂O₂

Masse moléculaire : 312.4

Ref: BE-RMCP017023

Palonosetron N-oxide

CAS : 813425-83-1

Palonosetron N-oxide is a n-oxide of palonosetron that was synthesized by reacting the drug with nitric acid. It is an impurity in the synthesis of palonosetron, which is used to treat severe nausea and vomiting. The solvents used in this reaction are dimethylsulfoxide (DMSO) and water. The parameters involved were temperature, time, and concentration. Impurities were detected using thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), and mass spectrometry (MS). The chemical structure of Palonosetron N-oxide is shown below: The equation for the synthesis of Palonosetron N-oxide is as follows: 2PALONOSETRON + HNO3 → PN-OXIDE + 2H2O+NOx

Formule : C₁₉H₂₄N₂O₂

Degré de pureté : Min. 95%

Masse moléculaire : 312.41 g/mol

Ref: 3D-FP26742