CAS 815595-14-3

1,3-Propanediamine, N3-[4-[6-(4-fluorophenyl)imidazo[2,1-b]oxazol-5-yl]-2-pyrimidinyl]-N1,N1,2,2-tetramethyl-

Formule : C₂₂H₂₅FN₆O

InChI : InChI=1S/C22H25FN6O/c1-22(2,14-28(3)4)13-25-20-24-10-9-17(26-20)19-18(15-5-7-16(23)8-6-15)27-21-29(19)11-12-30-21/h5-12H,13-14H2,1-4H3,(H,24,25,26)

Code InChI : CDZPSYGUMJXDLL-UHFFFAOYSA-N

SMILES : CC(C)(CNC1=NC=CC(=N1)C2=C(N=C3N2C=CO3)C4=CC=C(C=C4)F)CN(C)C

Synonymes :

• 1,3-Propanediamine, N3-[4-[6-(4-fluorophenyl)imidazo[2,1-b]oxazol-5-yl]-2-pyrimidinyl]-N1,N1,2,2-tetramethyl-

p38 Kinase inhibitor 7

CAS : 815595-14-3

p38 Kinase inhibitor 7 (Comp:XXXIX) is an inhibitor of p38α, with an IC₅₀ value of 5.25 nM. It also effectively suppresses TNFα production in THP-1 cells, demonstrating an IC₅₀ of 5.88 nM.

Formule : C₂₂H₂₅FN₆O

Couleur et forme : Solid

Masse moléculaire : 408.472

Ref: TM-T205102