CAS 83-74-9

(-)-Ibogaïne

Formule : C₂₀H₂₆N₂O

InChI : InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13+,17+,20+/m1/s1

Code InChI : InChIKey=HSIBGVUMFOSJPD-CFDPKNGZSA-N

SMILES : C(C)[C@@H]1[C@]2([C@@]3(C4=C(C=5C(N4)=CC=C(OC)C5)CC[N@]2C[C@@](C3)(C1)[H])[H])[H]

Synonymes :

• 6,9-Methano-5H-pyrido[1′,2′:1,2]azepino[4,5-b]indole, ibogamine deriv.
• 7-Ethyl-6,6beta,7,8,9,10,12,13-octahydro-2-methoxy-6,9-methano-5H-pyrido(1',2':1,2)azepino(5,4-b)indole
• DEA No. 7260
• Endabuse
• Ibogain
• Ibogaine
• Ibogaine (8CI)
• Ibogamine, 12-methoxy-
• Nih 10567
• Nsc 249764
• Tabernanthe iboga
• Unii-3S814I130U
• 12-Methoxyibogamine

Ibogaine

CAS : 83-74-9

Formule : C₂₀H₂₆N₂O

Couleur et forme : White To Off-White Solid

Masse moléculaire : 310.44

Ref: 4Z-I-357

Ibogaine-13C-d3

CAS : 83-74-9

Formule : C₁₉₁₃CH₂₃D₃N₂O

Couleur et forme : White To Off-White Solid

Masse moléculaire : 314.45

Ref: 4Z-I-352

Ibogaine

Produit contrôlé

CAS : 83-74-9

Ibogaine is a psychoactive substance, which is an indole alkaloid derived from the root bark of the Tabernanthe iboga plant. This plant is native to Central Africa and has been traditionally used in spiritual and healing ceremonies by indigenous communities. Ibogaine acts primarily as a serotonergic and dopaminergic system modulator, exhibiting complex interactions at several neurotransmitter systems, including NMDA receptors and sigma-2 receptors, and functioning as an antagonist at the α3β4 nicotinic acetylcholine receptors.Current research focuses on its potential applications in interrupting substance addiction cycles, particularly for opioids and stimulants, by reducing withdrawal symptoms and cravings. Its ability to induce an altered state of consciousness is also being studied in the context of psychotherapy. However, the administration of Ibogaine requires careful clinical oversight due to its potent psychoactive effects and potential cardiac risks. Preclinical and clinical studies continue to investigate its efficacy and safety profile, with a focus on understanding the neurobiological mechanisms underlying its therapeutic benefits.

Formule : C₂₀H₂₆N₂O

Degré de pureté : Min. 98 Area-%

Couleur et forme : Powder

Masse moléculaire : 310.43 g/mol

Ref: 3D-FI159190