CAS 857086-93-2

Formule : C32H31BrN2O2

InChI : InChI=1S/C32H31BrN2O2/c1-35(2)19-18-32(36,28-15-9-13-22-10-7-8-14-26(22)28)30(23-11-5-4-6-12-23)27-21-24-20-25(33)16-17-29(24)34-31(27)37-3/h4-17,20-21,30,36H,18-19H2,1-3H3/t30-,32-/m0/s1

Code InChI : QUIJNHUBAXPXFS-CDZUIXILSA-N

SMILES : CN(C)CC[C@](C1=CC=CC2=CC=CC=C21)([C@@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O

(1S,2R)-Bedaquiline

CAS : 857086-93-2

(1S,2R)-Bedaquiline

Formule : C₃₂H₃₁BrN₂O₂

Degré de pureté : 98%

Masse moléculaire : 555.5

Ref: 54-OR1033208

(1S,2R)-1-(6-BROMO-2-METHOXYQUINOLIN-3-YL)-4-(DIMETHYLAMINO)-2-(NAPHTHALEN-1-YL)-1-PHENYLBUTAN-2-OL

CAS : 857086-93-2

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 555.5159912

Ref: 10-F824432

(aR,bS)-Bedaquiline

Produit contrôlé

CAS : 857086-93-2

Applications (αR,βS)-Bedaquiline is an intermediate in the synthesis of (αS,βR)-Bedaquiline (B119540), which is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References Cheepsattayakorn, A., et al.: Anti-Infect. Drug. Discover.,7, 141 (2012); de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);

Formule : C₃₂H₃₁BrN₂O₂

Couleur et forme : Neat

Masse moléculaire : 555.5

Ref: TR-B119535

(±R,²S)-Bedaquiline

CAS : 857086-93-2

(±R,²S)-Bedaquiline is a diarylquinoline that is used in the treatment of drug-resistant tuberculosis. It has shown efficacy against multidrug-resistant tuberculosis and has been shown to reverse abnormal changes in bacterial DNA induced by injury. Bedaquiline displays antimycobacterial activity and is typically used as part of a multidrug regimen for the treatment of tuberculosis. Clinical trials have demonstrated that bedaquiline can improve pulmonary function, reduce the risk of decline in lung function, and improve survival rates for patients with drug-resistant tuberculosis.

Formule : C₃₂H₃₁BrN₂O₂

Degré de pureté : Min. 95%

Masse moléculaire : 555.5 g/mol

Ref: 3D-HJB08693

(1S,2R)-Bedaquiline

CAS : 857086-93-2

(1S,2R)-Bedaquiline ((1S,2R)-TMC207) is a pharmaceutical intermediate utilized in the synthesis of various active compounds.

Formule : C₃₂H₃₁BrN₂O₂

Couleur et forme : Solid

Masse moléculaire : 555.51

Ref: TM-TYD-03302

(1S,2R)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(methylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol

CAS : 857086-93-2

Formule : C₃₂H₃₁BrN₂O₂

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 555.5047

Ref: IN-DA00G3QK