CAS 923-61-5
:1,2-Dipalmitoyl-sn-glycéro-3-phosphoéthanolamine
Description :
1,2-Dipalmitoyl-sn-glycéro-3-phosphoéthanolamine (DPPE) est un phospholipide couramment utilisé en biochimie et en biologie cellulaire. Il se caractérise par ses deux chaînes d'acide palmitique, qui sont des acides gras saturés, contribuant à ses propriétés hydrophobes. La molécule présente un squelette de glycérol estérifié à deux chaînes d'acides gras aux première et deuxième positions, tandis que la troisième position est liée à un groupe phosphoéthanolamine. Cette structure confère des caractéristiques amphiphiles, permettant au DPPE de former des bicouches et des vésicules dans des environnements aqueux, ce qui le rend essentiel dans les études de membranes et les systèmes de délivrance de médicaments. Le DPPE est souvent utilisé dans la formulation de liposomes et comme composant dans des bicouches lipidiques pour diverses applications, y compris l'étude de la dynamique des membranes et des interactions protéiques. Sa stabilité et sa compatibilité avec les systèmes biologiques en font un outil précieux dans la recherche et le développement pharmaceutique. De plus, le DPPE peut participer à diverses réactions biochimiques, y compris celles impliquant la fusion des membranes et les voies de signalisation cellulaire.
Formule :C37H74NO8P
InChI :InChI=1/C37H74NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(39)43-33-35(34-45-47(41,42)44-32-31-38)46-37(40)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h35H,3-34,38H2,1-2H3,(H,41,42)/t35-/m1/s1
Code InChI :InChIKey=SLKDGVPOSSLUAI-PGUFJCEWSA-N
SMILES :[C@@H](OC(CCCCCCCCCCCCCCC)=O)(COC(CCCCCCCCCCCCCCC)=O)COP(OCCN)(=O)O
Synonymes :- (2R)-3-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexadecanoyloxy)propyl hexadecanoate
- (R)-Dipalmitoylphosphatidylethanolamine
- 1,2-Dihexadecanoyl-sn-glycerol-3-phosphorylethanolamine
- 1,2-Dipalmitoyl-3-sn-phosphatidylethanolamine
- 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-3-phosphatidylethanolamine
- 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-α-phosphatidylethanolamine
- 1,2-Dipalmitoyl-L-3-phosphatidylethanolamine
- 1,2-Dipalmitoyl-L-a-phosphatidylethanolamine
- 1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-Ethanolamine
- 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylethanolamine
- 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
- 1,2-Dipalmitoyl-sn-glycero-3-phosphorylethanolamine
- 1,2-Dipalmitoyl-sn-glycerol-3-<span class="text-smallcaps">L</span>-α-phosphorylethanolamine
- 1,2-Dipalmitoyl-sn-glycerol-3-L-a-phosphorylethanolamine
- 1,2-Dipalmitoyl-sn-glycerol-3-phosphatidylethanolamine
- 1,2-Dipalmitoyl-sn-glycerol-3-phosphoethanolamine
- 1,2-Dipalmitoyl-sn-glycerol-3-phosphorylethanolamine
- 1,2-Dipalmitoyl-sn-glycerophosphoethanolamine
- 1,2-Dipalmitoylglycerophosphorylethanolamine
- 2-Azaniumylethyl [(2R)-2,3-di(hexadecanoyloxy)propyl] phosphate
- <span class="text-smallcaps">L</span>-α-Dipalmitoylphosphatidylethanolamine
- <span class="text-smallcaps">L</span>-β,γ-Dipalmitoyl-α-phosphatidylethanolamine
- Coatsome ME 6060
- Dhpe
- Dipalmitoyl-1-Α-Phosphatidyl Ethanolamine
- Dipalmitoyl-<span class="text-smallcaps">L</span>-α-cephalin
- Dipalmitoyl-<span class="text-smallcaps">L</span>-α-phosphatidylethanolamine
- Dipalmitoyl-L-ALPHA-phosphatidyl ethanolamine
- Dipalmitoyl-L-a-cephalin
- Dipalmitoyl-L-a-phosphatidylethanolamine
- Hexadecanoic acid, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
- Hexadecanoic acid, 1,1′-[(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester
- Hexadecanoic acid,1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, (R)-
- Hexadecanoicacid, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediylester (9CI)
- L-a-Dipalmitoylphosphatidylethanolamine
- L-b,g-Dipalmitoyl-a-phosphatidylethanolamine
- Palmitin, 1,2-di-, 2-aminoethyl hydrogen phosphate, <span class="text-smallcaps">L</span>-
- Palmitin, 1,2-di-, 2-aminoethyl hydrogen phosphate, L- (8CI)
- Sn-1,2-Dipalmitoylglycerophosphoethanolamine
- Palmitin, 1,2-di-, 2-aminoethyl hydrogen phosphate, L-
- [(2R)-1-[2-azanylethoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] hexadecanoate
- L-ALPHA-PHOSPHATIDYLETHANOLAMINE, DIPALMITOYL
- 1,2-Dipalmitoyl-sn-glycero-3-PE
- L-β,γ-Dipalmitoyl-α-cephalin
- O-(1-O,2-O-Dihexadecanoyl-L-glycero-3-phospho)-2-aminoethanol
- CAS_923-61-5
- 1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine, 1,2-dipalmitoyl, L-α-Phosphatidylethanolamine, dipalmitoyl, L-β,γ-Dipalmitoyl-α-cephalin
- 2-Aminoethyl (R)-2,3-Bis(hexadecanoyloxy)propyl Hydrogen Phosphate
- 3-SN-PHOSPHATIDYLETHANOLAMINE, 1,2-DIPALMITOYL
- L-BETA,GAMMA-DIPALMITOYL-ALPHA-CEPHALIN
- L-α-Phosphatidylethanolamine, dipalmitoyl
- Dihexadecanoylphosphatidylethanolamine
- Dipalmitoyl phosphoethanolamine
- (R)-1-[[[(2-aminoethoxy)hydroxyphosphinoyl]oxy]methyl]ethane-1,2-diyl dihexadecanoate
- DPPE L-2116
- 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine,99%+
- PE(16:0/16:0)
- L-b,g-DipalMitoyl-a-cephalin, DPPE
- 1,2-dipalmitoyl
- DIPALMITOYL PHOSPHATIDYL ETHANOLAMINE
- palmitic acid [(1R)-1-[[2-aminoethoxy(hydroxy)phosphoryl]oxymethyl]-2-hexadecanoyloxy-ethyl] ester
- [(2R)-1-[2-aminoethoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] hexadecanoate
- 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine(DPPE)
- Hexadecanoic acid,1,1'-[(1R)-1-[[[(3-amino-1-oxopropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl]ester
- 2-[(1-O,2-O-Dipalmitoyl-L-glycero-3-phospho)oxy]ethylamine
- 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine>
- dipalmitoyl
- (2R)-3-(((2-aMinoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalMitate
- L-DPPE
- Hexadecanoic acid, (1R)-1-(2-aminoethoxy)hydroxyphosphinyloxymethyl-1,2-ethanediyl ester
- (+)-2-[[(R)-1-O,2-O-Dipalmitoyl-L-glycero-3-phospho]oxy]ethanamine
- GPEtn(16:0/16:0)[U]
- beta,gamma-dipalmitoyl-alpha-cephalin
- L-ALPHA-PHOSPHATIDYLETHANOLAMINE, DIPALMITOYL (C16:0)
- 1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
- L-A-PHOSPHATIDYLETHANOLAMINE, DIPALM
- Voir plus de synonymes
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1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
CAS :Formule :C37H74NO8PDegré de pureté :>96.0%(HPLC)Couleur et forme :White to Almost white powder to crystalineMasse moléculaire :691.971,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
CAS :Bachem ID: 4005625.
Formule :C37H74NO8PDegré de pureté :> 99%Couleur et forme :White PowderMasse moléculaire :691.971,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
CAS :1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamineFormule :C37H74NO8PCouleur et forme :SolidMasse moléculaire :691.959121,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
CAS :1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamineFormule :C37H74NO8PDegré de pureté :99.5%Masse moléculaire :691.961,2-Dipalmitoyl-sn-Glycero-3-Phosphatidylethanolamine
CAS :Formule :C37H74NO8PDegré de pureté :>99%Couleur et forme :SolidMasse moléculaire :691.961,2-Dipalmitoyl-sn-glycero-3-phosphorylethanolamine
CAS :Produit contrôléApplications 1,2-Dipalmitoyl-sn-glycero-3-phosphorylethanolamine used in the synthesis ultra-thin membranes to facilitate the transfer of islets of Langerhans in the attenuation of early graft loss in avoidance of immunosuppressive therapy. Also used in the synthesis of immunoliposomes containing TAT cells for tumor cell internalization and cytotoxicity.
References Teramura, Y, et al.: Biomat., 34, 2683 (2013); Koren, E. et al.: J. Control. Rel., 160, 264 (2012);Formule :C37H74NO8PCouleur et forme :NeatMasse moléculaire :691.96(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate
CAS :(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitateFormule :C37H74NO8PDegré de pureté :98%Masse moléculaire :691.961,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
CAS :DPPE, a phospholipid, thickens membranes with Ca2+ and cholesterol.Formule :C37H74NO8PDegré de pureté :98% - 99.71%Couleur et forme :White SolidMasse moléculaire :691.95911,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
CAS :1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that plays an important role in many cellular processes. It is a major component of the lipid bilayer that surrounds cells and provides stability to the membrane. 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine can form hydrogen bonding interactions with other molecules in the cytoplasm. The redox potential of this compound is also high enough to allow it to participate in oxidation reactions. This phospholipid also has a phase transition temperature at which it changes from a liquid state to a solid state at room temperature. 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine can be used as a reaction mechanism for synthesizing glycosylated proteins or lipids. In vitro assays have been performed using this compound asFormule :C37H74NO8PMasse moléculaire :691.96 g/mol
