CAS 926232-01-1

Formule : C11H8N2O3S

InChI : InChI=1S/C11H8N2O3S/c14-10(7-1-4-12-5-2-7)13-8-3-6-17-9(8)11(15)16/h1-6H,(H,13,14)(H,15,16)

Code InChI : MQJQQTDTQYSZMN-UHFFFAOYSA-N

SMILES : C1=CN=CC=C1C(=O)NC2=C(SC=C2)C(=O)O

3-(Pyridine-4-amido)thiophene-2-carboxylic acid

CAS : 926232-01-1

3-(Pyridine-4-amido)thiophene-2-carboxylic acid is a ligand for the human receptors CXCR4 and CCR5. It has been shown to activate both receptor types by binding to their extracellular domains. 3-(Pyridine-4-amido)thiophene-2-carboxylic acid has been shown to inhibit HIV infection of cells in vitro, and was identified as a potential inhibitor of HIV entry into cells. 3-(Pyridine-4-amido)thiophene-2-carboxylic acid also binds to proteins such as GTPase RhoA and inhibits its activity, which may be responsible for some of its biological effects.

Formule : C₁₁H₈N₂O₃S

Degré de pureté : Min. 95%

Masse moléculaire : 248.26 g/mol

Ref: 3D-BMB23201