CAS 93413-90-2
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11 produits concernés.
N-Desmethylvenlafaxine Hydrochloride 1.0 mg/ml in Methanol (as free base)
CAS :Couleur et forme :Single SolutionVenlafaxine Related Compound A (1-(1-(4-Methoxyphenyl)-2-(methylamino)ethyl)cyclohexanol hydrochloride)
CAS :Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFormule :C16H25NO2·HClCouleur et forme :White SolidMasse moléculaire :263.18853(±)-N-desmethyl Venlafaxine (hydrochloride)
CAS :Formule :C16H26ClNO2Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :299.8361Venlafaxine EP Impurity D HCl (Venlafaxine USP Related Compound A, N-Desmethyl Venlafaxine HCl)
CAS :Formule :C16H25NO2·HClCouleur et forme :White To Off-White SolidMasse moléculaire :263.38 36.461-[(1RS)-1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride
CAS :Produit contrôléFormule :C16H25NO2·ClHCouleur et forme :NeatMasse moléculaire :299.84Venlafaxine EP Impurity D-13C-d3 HCl (Venlafaxine USP Related Compound A-13C-d3, N-Desmethyl Venlafaxine-13C-d3 HCl)
CAS :Formule :C1513CH22D3NO2·HClMasse moléculaire :267.39 36.461-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride(rac N-Desmethyl Venlafaxine Hydrochloride)
CAS :<p>Impurity Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A<br>Applications 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride (Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A) is a metabolite of Venlafaxine (V120000), which is a selective serotonin noradrenaline reuptake inhibitor, used as an antidepressant.<br>References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000);<br></p>Formule :C16H25NO2·ClHCouleur et forme :WhiteMasse moléculaire :299.841-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride
CAS :<p>1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride is a drug product that is not yet approved for use in humans. It is an impurity found in the drug cyclosporine, which is used to treat psoriasis and other skin conditions. 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride has been shown to be inactive in the metabolism studies of rats and dogs. This impurity was detected by HPLC with UV detection at 254 nm, but it did not show any significant absorption at 280 nm. The purity of this compound was determined to be 97% by NMR analysis and HPLC.</p>Formule :C16H25NO2·HClDegré de pureté :Min. 95%Masse moléculaire :299.84 g/mol(±)-N-desmethyl Venlafaxine hydrochloride
CAS :(±)-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat synaptosome preparations, demonstrated by IC50 values of 4.7 and 1.6 µM, respectively. Clinically, it has been shown to counteract reserpine-induced hypothermia in mice, displaying efficacy at a minimum effective dose (MED) of 10 mg/kg.Formule :C16H26ClNO2Couleur et forme :SolidMasse moléculaire :299.836
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