CAS 93413-90-2

Formule : C16H26ClNO2

InChI : InChI=1S/C16H25NO2.ClH/c1-17-12-15(16(18)10-4-3-5-11-16)13-6-8-14(19-2)9-7-13;/h6-9,15,17-18H,3-5,10-12H2,1-2H3;1H

Code InChI : HWPAFKGYJZARRM-UHFFFAOYSA-N

SMILES : CNCC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl

Venlafaxine Related Compound A

CAS : 93413-90-2

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formule : C₁₆H₂₅NO₂·HCl

Couleur et forme : White Solid

Masse moléculaire : 263.18853

Ref: 45-1711279

1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride

CAS : 93413-90-2

Formule : C₁₆H₂₆ClNO₂

Degré de pureté : 95%

Couleur et forme : Solid

Masse moléculaire : 299.8361

Ref: IN-DA00GW6P

Venlafaxine EP Impurity D HCl (Venlafaxine USP Related Compound A, N-Desmethyl Venlafaxine HCl)

CAS : 93413-90-2

Formule : C₁₆H₂₅NO₂·HCl

Couleur et forme : White To Off-White Solid

Masse moléculaire : 263.38 36.46

Ref: 4Z-V-035

N-Desmethylvenlafaxine Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS : 93413-90-2

Couleur et forme : Single Solution

Ref: 61-AMP0393.04-01

(±)-N-desmethyl Venlafaxine hydrochloride (Standard)

CAS : 93413-90-2

(±)-N-desmethyl Venlafaxine hydrochloride (Standard) is a reference standard for research and analysis in studies involving (±)-N-desmethyl Venlafaxine hydrochloride. (±)-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat synaptosome preparations, demonstrated by IC50 values of 4.7 and 1.6 µM, respectively. Clinically, it has been shown to counteract reserpine-induced hypothermia in mice, displaying efficacy at a minimum effective dose (MED) of 10 mg/kg.

Formule : C₁₆H₂₆ClNO₂

Couleur et forme : Solid

Masse moléculaire : 299.84

Ref: TM-TMSM-3583

N-Desmethylvenlafaxine Hydrochloride

CAS : 93413-90-2

Couleur et forme : Neat

Ref: 61-FOR0393.04

1-[(1RS)-1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride

Produit contrôlé

CAS : 93413-90-2

Formule : C₁₆H₂₅NO₂·ClH

Couleur et forme : Neat

Masse moléculaire : 299.84

Ref: 86-MM0393.04

1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride(rac N-Desmethyl Venlafaxine Hydrochloride)

CAS : 93413-90-2

Impurity Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A
Applications 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride (Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A) is a metabolite of Venlafaxine (V120000), which is a selective serotonin noradrenaline reuptake inhibitor, used as an antidepressant.
References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000);

Formule : C₁₆H₂₅NO₂·ClH

Couleur et forme : Neat

Masse moléculaire : 299.84

Ref: TR-M266250

Venlafaxine EP Impurity D-13C-d3 HCl (Venlafaxine USP Related Compound A-13C-d3, N-Desmethyl Venlafaxine-13C-d3 HCl)

CAS : 93413-90-2

Formule : C₁₅₁₃CH₂₂D₃NO₂·HCl

Masse moléculaire : 267.39 36.46

Ref: 4Z-V-0345

rac N-Desmethyl Venlafaxine hydrochloride in Methanol(as free base)

CAS : 93413-90-2

Methanol(as free base)

Ref: BE-MU-7883YM-1000

1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride

CAS : 93413-90-2

1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride is a drug product that is not yet approved for use in humans. It is an impurity found in the drug cyclosporine, which is used to treat psoriasis and other skin conditions. 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride has been shown to be inactive in the metabolism studies of rats and dogs. This impurity was detected by HPLC with UV detection at 254 nm, but it did not show any significant absorption at 280 nm. The purity of this compound was determined to be 97% by NMR analysis and HPLC.

Formule : C₁₆H₂₅NO₂·HCl

Degré de pureté : Min. 95%

Masse moléculaire : 299.84 g/mol

Ref: 3D-IM63866

(±)-N-desmethyl Venlafaxine hydrochloride

CAS : 93413-90-2

(±)-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat synaptosome preparations, demonstrated by IC50 values of 4.7 and 1.6 µM, respectively. Clinically, it has been shown to counteract reserpine-induced hypothermia in mice, displaying efficacy at a minimum effective dose (MED) of 10 mg/kg.

Formule : C₁₆H₂₆ClNO₂

Couleur et forme : Solid

Masse moléculaire : 299.84

Ref: TM-T84941