
CAS 952652-79-8
:Formule :C23H27N5O3
InChI :InChI=1S/C23H27N5O3/c1-4-7-20(29)28(21(15(2)3)23(30)31)14-16-10-12-17(13-11-16)18-8-5-6-9-19(18)22-24-26-27-25-22/h5-6,8-13,15,21H,4,7,14H2,1-3H3,(H,30,31)(H,24,25,26,27)/t21-/m0/s1
Code InChI :OKAQHVJSXLGXET-NRFANRHFSA-N
SMILES :CCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O
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Valsartan Related Compound B
CAS :Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoiFormule :C23H27N5O3Couleur et forme :White PowderMasse moléculaire :421.21139(S)-2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)butyramido)-3-methylbutanoic acid
CAS :(S)-2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)butyramido)-3-methylbutanoic acidFormule :C23H27N5O3Degré de pureté :95%Masse moléculaire :421.49Valsartan EP Impurity C (Valsartan USP Related Compound B)
CAS :Formule :C23H27N5O3Couleur et forme :Off-White SolidMasse moléculaire :421.50(S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)butyramido)-3-methylbutanoic acid
CAS :Formule :C23H27N5O3Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :421.4922(2S)-2-[Butanoyl[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]-3-methylbutanoic Acid
CAS :Formule :C23H27N5O3Couleur et forme :NeatMasse moléculaire :421.49Valsartan n-Propyl Impurity
CAS :Produit contrôléImpurity Valsartan Related Compound B
Applications Valsartan n-Propyl is an impurity in the synthesis of Valsartan (V095750). Valsartan USP Related Compound B.
References Hillaert, S., et al.: J. Pharm. Biomed. Anal., 31, 329 (2003), Carlucci, G., et al.: Anal. Lett., 33, 2491 (2000), Cagigal, E., et al.: Talanta, 54, 1121 (2001),Formule :C23H27N5O3Couleur et forme :NeatMasse moléculaire :421.49Valsartan Impurity 46
CAS :Formule :C25H31N5O3Couleur et forme :Off-White SolidMasse moléculaire :449.56(S)-N-Butyryl-N-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]valine
CAS :(S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)butyramido)-3-methylbutanoic acidFormule :C23H27N5O3Degré de pureté :98%Masse moléculaire :421.49N-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
CAS :N-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine (GW1929) is a potent vasodilator that is used for the treatment of hypertension. It is synthesized by condensation of sodium hydroxide with 2-(4′-chlorophenyl)piperazine followed by methyl esterification and chloride acylation. The synthesis of GW1929 has been accomplished in two steps: carbonate cyclization and valsartan hydrolysis. In the first step, the carboxylic acid group of GW1929 was converted to its corresponding chloride compound which was then reacted with methyl bromide to yield the desired product. The second step involved hydrolysis of GW1929 with potassium carbonate, after which it was oxidized with azide to form an ester. SodiumFormule :C23H27N5O3Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :421.49 g/mol








