
CAS 956903-21-2
:Formule :C18H27NO3
InChI :InChI=1S/C18H27NO3/c1-11(2)6-13-10-19-5-4-12-7-17(21)18(22-3)8-14(12)15(19)9-16(13)20/h7-8,11,13,15-16,20-21H,4-6,9-10H2,1-3H3/t13-,15-,16-/m1/s1
Code InChI :NNGHNWCGIHBKHE-FVQBIDKESA-N
SMILES :CC(C)C[C@@H]1CN2CCC3=CC(=C(C=C3[C@H]2C[C@H]1O)OC)O
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(2R,3R,11bR)-rel-9-deMe-DTBZ
CAS :Produit contrôléApplications (+/-)-9-deMe-DTBZ is a desmethyl derivative of Tetrabenzine (T284000), a dopamine depleting agent. An antidyskinetic; antipsychotic.
References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),Formule :C18H27NO3Couleur et forme :NeatMasse moléculaire :305.41(2R,3R,11Br)-rel-9-deme-dtbz
CAS :(2R,3R,11Br)-rel-9-deme-dtbz is an analog of tolvaptan that has potent anticancer properties. It acts as a kinase inhibitor and induces apoptosis in cancer cells. This compound has been shown to inhibit the activity of several kinases, including protein kinase B (AKT), mitogen-activated protein kinase (MAPK), and extracellular signal-regulated kinase (ERK). It also inhibits the growth of human tumor xenografts in Chinese hamsters. Additionally, (2R,3R,11Br)-rel-9-deme-dtbz has been found to be a promising candidate for the treatment of cancer due to its high selectivity towards cancer cells and low toxicity towards normal cells. Its potent anticancer activity makes it a valuable tool for cancer research and drug development.Formule :C18H27NO3Degré de pureté :Min. 95%Masse moléculaire :305.4 g/mol

