CAS 97233-06-2

Cinnamtannin D1

Formule : C₄₅H₃₆O₁₈

InChI : InChI=1S/C45H36O18/c46-18-10-27(54)33-31(11-18)62-45(17-3-6-22(49)26(53)9-17)44(59)38(33)36-32(63-45)14-29(56)35-37(39(58)41(61-43(35)36)16-2-5-21(48)25(52)8-16)34-28(55)13-23(50)19-12-30(57)40(60-42(19)34)15-1-4-20(47)24(51)7-15/h1-11,13-14,30,37-41,44,46-59H,12H2/t30-,37-,38+,39+,40+,41+,44+,45-/m0/s1

Code InChI : BYSRPHRKESMCPO-HMQYECKYSA-N

SMILES : C1[C@@H]([C@H](OC2=C1C(=CC(=C2[C@@H]3[C@H]([C@H](OC4=C3C(=CC5=C4[C@@H]6[C@H]([C@](O5)(OC7=CC(=CC(=C67)O)O)C8=CC(=C(C=C8)O)O)O)O)C9=CC(=C(C=C9)O)O)O)O)O)C1=CC(=C(C=C1)O)O)O

Synonymes :

• 2β→O→7)-epicatechin-(4β→8)-catechin
• epicatechin-(4β→8
• Cinnamtannin D1

Cinnamtannin D1

CAS : 97233-06-2

Cinnamtannin D1 is an orally active polyphenolic compound that modulates the Th17/Treg cell balance by inhibiting AHR expression. It reduces apoptosis and ROS in INS-1 cells and primary cultured mouse islets induced by Palmitic acid (PA). Cinnamtannin D1 mitigates Th17 cell differentiation by downregulating p-STAT3/RORγt and enhances Treg cell differentiation by upregulating p-STAT5/Foxp3. In a collagen-induced arthritis (CIA) mouse model, it demonstrates excellent anti-arthritic efficacy. Cinnamtannin D1 is applicable for rheumatoid arthritis (RA) research.

Formule : C₄₅H₃₆O₁₈

Masse moléculaire : 864.77

Ref: TM-TN13118

Cinnamtannin D1

CAS : 97233-06-2

Oxygen-heterocyclic compound

Formule : C₄₅H₃₆O₁₈

Masse moléculaire : 864.76

Ref: 5G-26027