CAS 99290-97-8

(1Z,3R,4R,5S,6R,9R,10S,11S,12R,13R,15R)-10-[(2,6-Didésoxy-3-C-méthyl-3-O-méthyl-α-L-ribo-hexopyranosyl)oxy]-6-éthyl-4,5-dihydroxy-3,5,9,11,13,15-hexaméthyl-12-[[3,4,6-tridésoxy-3-(diméthylamino)-β-D-xylo-hexopyranosyl]oxy]-7,16-dioxa-2-azabicyclo[11.2.1]hexadéc-1-én-8-one

Formule : C₃₇H₆₆N₂O₁₂

InChI : InChI=1S/C37H66N2O12/c1-14-25-37(10,44)29(41)22(6)38-32-18(2)16-36(9,51-32)31(50-34-27(40)24(39(11)12)15-19(3)46-34)20(4)28(21(5)33(43)48-25)49-26-17-35(8,45-13)30(42)23(7)47-26/h18-31,34,40-42,44H,14-17H2,1-13H3/b38-32-/t18-,19-,20+,21-,22-,23+,24+,25-,26+,27-,28+,29-,30+,31-,34+,35-,36-,37-/m1/s1

Code InChI : InChIKey=BPENQAXMHXRNMD-ULJZSMOKSA-N

SMILES : O([C@H]1[C@]2(C)O/C(/[C@H](C)C2)=N\[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@H](C)[C@@H](O[C@H]3C[C@](OC)(C)[C@@H](O)[C@H](C)O3)[C@@H]1C)[C@H]4[C@H](O)[C@@H](N(C)C)C[C@@H](C)O4

Synonymes :

• (1Z,3R,4R,5S,6R,9R,10S,11S,12R,13R,15R)-10-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-6-ethyl-4,5-dihydroxy-3,5,9,11,13,15-hexamethyl-12-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-7,16-dioxa-2-azabicyclo[11.2.1]hexadec-1-en-8-one
• 7,16-Dioxa-2-azabicyclo[11.2.1]hexadec-1-en-8-one, 10-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-6-ethyl-4,5-dihydroxy-3,5,9,11,13,15-hexamethyl-12-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [3R-(3R*,4R*,5S*,6R*,9R*,10S*,11S*,12R*,13R*,15R*)]-
• 7,16-Dioxa-2-azabicyclo[11.2.1]hexadec-1-en-8-one, 10-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-6-ethyl-4,5-dihydroxy-3,5,9,11,13,15-hexamethyl-12-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (1Z,3R,4R,5S,6R,9R,10S,11S,12R,13R,15R)-

Erythromycin A (6,9-Imino Ether)

CAS : 99290-97-8

Formule : C₃₇H₆₆N₂O₁₂

Couleur et forme : White To Off-White Solid

Masse moléculaire : 730.94

Ref: 4Z-E-207

Erythromycin A 6,9-Imino Ether

CAS : 99290-97-8

Stability Hygroscopic
Applications An impurity in the synthesis of Erythromycin (E649950). An antibacterial.
References Zhang, L. et al.: J. Antibio., 64, 243 (2011); Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979),

Formule : C₃₇H₆₆N₂O₁₂

Couleur et forme : Neat

Masse moléculaire : 730.93

Ref: TR-E650015

Erythromycin A 6,9-imino ether

CAS : 99290-97-8

Erythromycin is a macrolide antibiotic that inhibits bacterial growth by binding to the 50S ribosomal subunit. It has been shown to have antibacterial activity against both staphylococci and streptococci. Erythromycin binds to the 23S ribosomal RNA, which prevents protein synthesis and cell division. The drug is used for the treatment of infections caused by bacteria susceptible to erythromycin, such as Group P2 (Streptococcus pneumoniae) and Group A (Staphylococcus aureus). Erythromycin also inhibits the biosynthesis of macrolactones, which are antibiotics related to erythromycin. These compounds are found in Streptomyces spp., Actinomycetes spp., and Mycobacterium smegmatis.

Formule : C₃₇H₆₆N₂O₁₂

Degré de pureté : Min. 95%

Couleur et forme : White To Off-White Solid

Masse moléculaire : 730.93 g/mol

Ref: 3D-FE146285

Erythromycin A Imino ether

CAS : 99290-97-8

Formule : C₃₇H₆₆N₂O₁₂

Masse moléculaire : 730.94

Ref: ST-EA-CP-E18023