Inhibiteur d’enzymes
Les inhibiteurs d'enzymes sont des composés qui diminuent ou arrêtent l'activité des enzymes, en se liant à celles-ci de manière spécifique. Ces inhibiteurs jouent un rôle crucial dans la régulation des processus biologiques et sont largement utilisés dans la recherche médicale et le développement de médicaments. En bloquant l'action des enzymes, ils permettent d'étudier la fonction enzymatique et de développer des traitements contre diverses maladies. Chez CymitQuimica, nous proposons une large gamme d'inhibiteurs enzymatiques de haute qualité pour soutenir vos recherches en biologie et en pharmacologie.
123 produits trouvés pour "Inhibiteur d’enzymes"
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Argatroban
CAS :Formule :C23H38N6O6SDegré de pureté :(HPLC) ≥ 98%Couleur et forme :White to off-white powderMasse moléculaire :526.65IU1
CAS :Formule :C18H21FN2ODegré de pureté :(TLC) ≥ 98%Couleur et forme :Off-white to pale brown solidMasse moléculaire :300.37Fumagillin
CAS :Formule :C26H34O7Degré de pureté :≥ 95.0%Couleur et forme :White, off-white or pale yellow to tan powderMasse moléculaire :458.54Vildagliptin
CAS :Formule :C17H25N3O2Degré de pureté :≥ 98.0%Couleur et forme :White to off-white powderMasse moléculaire :303.40Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride
CAS :Formule :C14H21ClN2O3S·HClDegré de pureté :(HPLC) ≥ 98.0%Couleur et forme :White powderMasse moléculaire :369.31Nafamostat
CAS :Formule :C19H17N5O2Degré de pureté :≥ 98.0%Couleur et forme :White to off-white powderMasse moléculaire :347.37Lactacystin
CAS :Formule :C15H24N2O7SDegré de pureté :≥ 95.0%Couleur et forme :White solid or powderMasse moléculaire :376.43E-64 protease inhibitor
CAS :Formule :C15H27N5O5Degré de pureté :(HPLC) ≥ 98.0%Couleur et forme :White crystalline powderMasse moléculaire :357.40Bestatin hydrochloride
CAS :Formule :C16H24N2O4·HClDegré de pureté :≥ 98.0% (dried basis)Couleur et forme :White to almost white powderMasse moléculaire :344.87Bortezomib
CAS :Formule :C19H25BN4O4Degré de pureté :≥ 98.0%Couleur et forme :White to off-white powder or solidMasse moléculaire :384.24Suramin sodium salt
CAS :Formule :C51H34N6Na6O23S6Degré de pureté :≥ 98%Couleur et forme :White to off-white powderMasse moléculaire :1429.16Phosphoramidon disodium salt
CAS :Formule :C23H32N3Na2O10PDegré de pureté :≥ 97.0%Couleur et forme :Colourless, transparent crystals or white to light yellow crystalline powderMasse moléculaire :587.47Nafamostat mesylate
CAS :Formule :C19H17N5O2Degré de pureté :≥ 99.0%Couleur et forme :White to off-white or beige crystalline powderMasse moléculaire :347.37Z-Leu-Leu-Leu-al
CAS :Formule :C26H41N3O5Degré de pureté :≥ 97.0%Couleur et forme :White to off-white powder or solidMasse moléculaire :475.63Carfilzomib
CAS :Formule :C40H57N5O7Degré de pureté :(HPLC) ≥ 98.0%Couleur et forme :White to off-white crystalline powder or crystalsMasse moléculaire :719.91DAPT
CAS :Formule :C23H26F2N2O4Degré de pureté :(NMR) ≥ 98.0%Couleur et forme :White to off-white solidMasse moléculaire :432.50N-p-Tosyl-L-phenylalanine chloromethyl ketone
CAS :Formule :C17H18ClNO3SDegré de pureté :(TLC) ≥ 98.0%Couleur et forme :White to off-white powderMasse moléculaire :351.85Leupeptin hemisulfate
CAS :Formule :C20H38N6O4·5H2SO4Degré de pureté :≥ 95%Couleur et forme :White to off-white powderMasse moléculaire :475.59Pepstatin A
CAS :Formule :C34H63N5O9Degré de pureté :≥ 98.0%Couleur et forme :White to off-white powderMasse moléculaire :685.90E-64d protease inhibitor
CAS :Formule :C17H30N2O5Degré de pureté :≥ 95.0%Couleur et forme :White powderMasse moléculaire :342.43Elastatinal microbial
CAS :Formule :C21H36N8O7Degré de pureté :~0.64μg/ml (IC50, pH8.8, 37°C)Couleur et forme :White to light-yellow or tan powderMasse moléculaire :512.60Z-VAD-FMK, cell permeable
CAS :Formule :C22H30FN3O7Degré de pureté :≥ 95.0%Couleur et forme :White to off-white solidMasse moléculaire :467.5AEBSF hydrochloride
CAS :Formule :C8H10FNO2S·HClDegré de pureté :≥ 98.0%Couleur et forme :White to off-white powder or solidMasse moléculaire :239.69Apricoxib
CAS :Produit contrôlé<p>Applications Apricoxib, is an orally active, selective COX-2 inhibitor, used as as an analgesic and anti-inflammatory agent, and also has anticancer potential, since COX-2 inhibition can reduce tumor growth and augment therapy.<br>References Kirane, A, et al.: Clinical Cancer Res., 18, 5031 (2012); Rohatagi, Sh., et al.: British J. Clin. Pharmaco., 66, 60 (2008);<br></p>Formule :C19H20N2O3SCouleur et forme :NeatMasse moléculaire :356.44Vitamin B12 e-Monocarboxylic Acid
CAS :<p>Stability Hygroscopic<br>Applications Vitamin B12 Monocarboxylic Acid is an impurity of Vitamin B12 (V676005) which is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.<br>References Rickes, et al.: Science, 107, 396 (1948); Kirschbaum, J., et al.: Anal. Profiles Drug Subs., 10, 183 (1981); Grasbeck, R., et al.: Clin. Biochem., 17, 99 (1984)<br></p>Formule :C63H87CoN13O15PCouleur et forme :Dark Red SolidMasse moléculaire :1356.35(3S,4S,3’S)-Ezetimibe
CAS :<p>Applications (3S,4S,3’S)-Ezetimbe is a 3-epimer impurity of Ezetimibe (E975000), a cholesterol absorption inhibitor.<br>References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>Formule :C24H21F2NO3Couleur et forme :Off-WhiteMasse moléculaire :409.43(3S,5S)-Atorvastatin Calcium Salt
CAS :Produit contrôlé<p>Impurity Atorvastatin Related Compound E<br>Applications Impuritiy of Atorvaststin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Atorvastatin Related Compound E<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),<br></p>Formule :C33H34FN2O5·CaCouleur et forme :NeatMasse moléculaire :1155.34N-(2-Hydroxyethyl)-1-deoxy-L-altronojirimycin Hydrochloride Salt
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications α-Glycosidase inhibitor.<br>References Jefferies, I., et al.: Bioorg. Med. Chem. Lett., 7, 1171 (1997), Hassan, A., et al.: Carbohydr. Res., 339, 1565 (2004),<br></p>Formule :C8H18ClNO5Couleur et forme :NeatMasse moléculaire :243.68522,5-Dideoxy-2,5-imino-D-mannitol
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A glucosidase inhibitor.<br>References Fellows, L.E.: Pestic. Sci., 17, 602 (1986)<br></p>Formule :C6H13NO4Couleur et forme :Off White SolidMasse moléculaire :163.17Nitromifene Citrate (E/Z mixture)
CAS :Produit contrôlé<p>Applications Nitromifene citrate is a non-steroidal estrogen antagonist. It is structurally similar to Tamoxifen (T006000) which is a selective estrogen response modifier (SERM).<br>References Rudick, C., et al.: Endorcrinol., 144, 179 (2003); Sutherland, R., et al.: Nature, 267, 434 (1977)<br></p>Formule :C33H36N2O11Couleur et forme :Yellow To OrangeMasse moléculaire :636.65N-(2-Hydroxyethyl)-1-deoxy-L-idonojirimycin Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications α-Glycosidase inhibitor.<br>References van de Water, F., et al.: Drug Metab. Rev., 37, 443 (2005), Koepsell, H., et al.: Pharm. Res., 24, 1227 (2007), Jappar, D., et al.: Pharm. Res., 26, 172 (2009),<br></p>Formule :C8H18ClNO5Couleur et forme :NeatMasse moléculaire :243.69Daidzein Diglucuronide
CAS :Produit contrôléFormule :C27H26O16Couleur et forme :White To Off-WhiteMasse moléculaire :606.49Teneligliptin Hydrobromide (2:5)
CAS :Produit contrôlé<p>Applications Teneligliptin Hydrobromide (2:5) is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion, and has a half-life of 24.2 hours in the human body.<br>References Goda, M. & Kadowaki, T.: Drugs Today, 49, 615 (2013); Kishimoto, M.: Diabetes Metab. Syndr. Obes., 6, 187 (2012)<br></p>Formule :C22H32·5Br2·5N6OSCouleur et forme :NeatMasse moléculaire :628.862-(Hydroxyamino)acetic Acid
CAS :Produit contrôlé<p>Applications 2-(Hydroxyamino)acetic Acid is a novel lactase inhibitor.<br>References Hattori, M., et al.: J. Insect Physiol., 51, 1359 (2005); Murao, S., et al.: Biosci. Biotech. Biochem., 56, 987 (1992)<br></p>Formule :C2H5NO3Couleur et forme :NeatMasse moléculaire :91.07Galacto-PUGNAc (>90%)
CAS :Produit contrôlé<p>Stability Moisture and Temperature Sensitive<br>Applications Galacto-PUGNAc is a highly selective inhibitor for β-hexosaminidases HEXA and HEXB is cell-permeable. Galacto-PUGNAc is able to modulate the activity of HEXA and HEXB in tissue culture, increasing ganglioside GM2 levels in neuroblastoma cells<br>References Stubbs, K.A. et al.: Angew. Chem. Int. Ed., 48, 1300 (2009);<br></p>Formule :C15H19N3O7Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :353.33Aprotinin Hydrochloride
CAS :<p>Applications Aprotinin is used in cardiac surgery to minimize bleeding and reduce exposure to blood products.<br>References Mangano, D. et al.: New Eng. J. Med., 354, 353 (2006); Fergusson, D. et al.: New. Eng. J. Med., 358, 2319 (2008);<br></p>Formule :C284H432N84O79S7·x(ClH)Couleur et forme :White SolidMasse moléculaire :6511.51(free amine)tert-Butyl (2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]-2-[(1,3-thiazolidin-3-yl)carbonyl]pyrrolidine-1-carboxylate
CAS :Produit contrôlé<p>Applications tert-Butyl (2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]-2-[(1,3-thiazolidin-3-yl)carbonyl]pyrrolidine-1-carboxylate is an orally anti-diabetic agent as a inhibitors of dipeptidylpeptidase IV (DPP-4).<br>References Yoshida, T., et al.: Bioorg. Med. Chem., 20, 5705-5719 (2012);<br></p>Formule :C27H38N6O3SCouleur et forme :NeatMasse moléculaire :526.69LCZ696
CAS :<p>Applications LCZ696 is a novel dual-acting inhibitor of angiotensin II receptor and neprilysin, which can be used for blood pressure reduction.<br>References Ruilope, L.M.; et al.: Lancet, 375, 1255 (2010)<br></p>Formule :C24H28NO5·C24H27N5O3·3Na·x(H2O)Couleur et forme :MixtureMasse moléculaire :479.48 + (433.47) + x(18.02)Abamine
CAS :Produit contrôlé<p>Applications Abamine is an inhibitor of 9-Cis-Epoxycarotenoid dioxygenase (NCED), the key regulatory enzyme in the plant hormone abscisic acid (ABA) biosynthesis pathway.<br>References Kitahata, N., et al.: Bioorg. Med. Chem., 14, 5555 (2006); Han, S., et al.: Bioorg. Med. Chem. Lett., 14, 3033 (2004)<br></p>Formule :C21H24FNO4Couleur et forme :NeatMasse moléculaire :373.42CP-10447
CAS :<p>Applications CP-10447 is an inhibitor apolipoprotein B (apoB) and triglyceride secretion in human hepatoma cells (HepG2) by inhibiting MTP activity and stimulating the early ER degradation of apoB. It is useful tool for further study of the mechanisms of apoB secretion and triglyceride-rich lipoprotein assembly.<br>References Haghpassand, M. et al.: J. Lipid. Res., 37, 1468 (1996); Pan, M. et al.: J. Biol. chem., 275, 27399 (2000);<br></p>Formule :C16H13BrN2OCouleur et forme :NeatMasse moléculaire :329.193'-Deoxyadenosine 5’-Diphosphate Triethylamine Salt (>90%)
CAS :<p>Stability Hygroscopic<br>Applications 3'-Deoxyadenosine 5’-Diphosphate Triethylamine Salt, is a nucleotide and was proposed to be a possible inhibitor of DNA synthesis.<br>References Frederiksen, Sune.: Biochimica et Biophysica Acta, 76(3), 366-71 (1963)<br></p>Formule :C10H15N5O9P2•xC6H15NDegré de pureté :>90%Couleur et forme :NeatMasse moléculaire :411.20 + x(101.19)Bis(2-butoxyethyl) 2-(3-Hydroxybutoxy)ethyl Phosphate Triester
CAS :Produit contrôlé<p>Applications Bis(2-butoxyethyl) 2-(3-Hydroxybutoxy)ethyl Phosphate Triester is derived from 2-Butoxyethanol (B692895), which is a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors.<br>References Sun, Y., et al.: Bioorg. Med. Chem. Lett., 21, 3798 (2011); Yi, W., et al.: Eur. J. Med. Chem., 45, 639 (2010)<br></p>Formule :C18H39O8PCouleur et forme :Colourless To Light YellowMasse moléculaire :414.47Nicotelline
CAS :Produit contrôlé<p>Applications Nicotelline is a Nicotine (N412420) related metabolite with potential as an inhibitor of human cytochrome P-450 2A6.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Denton, T. et al.: Biochem. Pharm., 67, 751 (2004); Gorrod, J. et al.: Anal. Det. Nic. Rel. Comp. Metab., 69, (1999);<br></p>Formule :C15H11N3Couleur et forme :NeatMasse moléculaire :233.27Naringenin chalcone
CAS :Produit contrôléFormule :C15H12O5Couleur et forme :NeatMasse moléculaire :272.25N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide Hydrochloride
CAS :Produit contrôlé<p>Applications Naphthalenesulfonamides derivatives are neoplasm inhibitors.<br>References Hidaka, H., et al.: Proc. Nat. Acad. Sci. USA, 78, 4354 (1981)<br></p>Formule :C20H29ClN2O2S·ClHCouleur et forme :NeatMasse moléculaire :433.44Avelestat
CAS :Produit contrôlé<p>Applications Avelstat inhibits plasma neutrophil elastase (NE) activity in zymosan-stimulated whole blood, and also inhibits NE activity on the surface of stimulated polymorphonuclear cells and in the supernatant of primed, stimulated cells.<br>References Stevens, T., et al.: J. Pharmacol. Exp. Ther., 339, 313 (2011)<br></p>Formule :C25H22F3N5O4SCouleur et forme :NeatMasse moléculaire :545.53Enviroxime
CAS :Produit contrôlé<p>Applications Enviroxime is a benzimidazole derivative that inhibits rhinovirus multiplication.<br>References De Long, D.C., et al.: J. Infect. Dis., 141, 87 (1980), Wikel, J.H., et al.: J. Med. Chem., 23, 368 (1980), Phillpotts, R.J., et al.: Lancet, 1, 1342 (1981), Haden, F.G., et al.: Antimicrob. Agents Chemother., 21, 892 (1982),<br></p>Formule :C17H18N4O3SCouleur et forme :NeatMasse moléculaire :358.41Benzyl Methyl Carbonate
CAS :Produit contrôlé<p>Applications Benzyl Methyl Carbonate is used in designing of inhibitors for serine and thiol proteases.<br></p>Formule :C9H10O3Couleur et forme :NeatMasse moléculaire :166.174,5,6,7-Tetrabromo-1H-benzotriazole
CAS :Produit contrôlé<p>Applications TBB is one of the most selective protein kinase inhibitors known, and when tested against a panel of 33 serine/threonine and tyrosine protein kinases, only three exhibited moderate inhibition by TBB, with Ki values one to two orders of magnitude higher than that for CK2.<br>References Boehning, D., et al.: Neuron, 40, 129 (2993)<br></p>Formule :C6HBr4N3Couleur et forme :NeatMasse moléculaire :434.71Chelerythrine Chloride
CAS :<p>Stability Hygroscopic<br>Applications Chelerythrine Chloride is a cell permeable protein kinase C (PKC) inhibitor.<br>References Song, L., et. al.: Brain Res., 1564, 52 (2014)<br></p>Formule :C21H18NO4·ClCouleur et forme :YellowMasse moléculaire :383.82(R)-Pinocembrin
CAS :Produit contrôlé<p>Applications (2R)-Pinocembrin is the (R)-enantiomer of Pinocembrin, a flavanoid with antioxidant activity found in damiana, honey, and propolis. (2R)-Pinocembrin is a potential inhibitor of PIM1 kinase, an oncogene that has been implicated in the development of leukemias, lymphomas, and prostate cancer.<br>References Zhao, J. et al.: J. Ethnopharmacol., 120, 387 (2008); Holder, S. et al.: Mol. Cancer Ther., 6, 163 (2007); Holder, S. et al.: Bioorg. Med. Chem., 15, 6463 (2007);<br></p>Formule :C15H12O4Couleur et forme :WhiteMasse moléculaire :256.25O,O-Dimethyl Dithiophosphate
CAS :Produit contrôléFormule :C2H7O2PS2Couleur et forme :ColourlessMasse moléculaire :158.18Morusin
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications Morusin is an inhibitor of human cervical cancer stem cell growth, attenuating NF-kB activity, and initiating apoptosis.<br>References Wang, L. et al.: Mol. Cell. Biochem., 379, 7 (2013);<br></p>Formule :C25H24O6Couleur et forme :NeatMasse moléculaire :420.45GDC 0152
CAS :Produit contrôlé<p>Applications GDC 0152 is a peptidomimetic small molecule antagonist of inhibitor of apoptosis (IAP) proteins with antitumor activity.<br>References Yue, Q., et. al.: Drug Metab. Dispos., 41, 508 (2013)<br></p>Formule :C25H34N6O3SCouleur et forme :NeatMasse moléculaire :498.64Ipidacrine Hydrochloride Hydrate
CAS :Formule :C12H16N2·ClH·H2OCouleur et forme :NeatMasse moléculaire :242.753a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol, can be used in the synthesis of Hexosaminidase inhibitors, which are the new drug candidates for the therapy of osteoarthritis.<br>References Liu, J. et al.: Chem. Bio., 8, 701 (2001);<br></p>Formule :C8H13NO4SCouleur et forme :White To Light BeigeMasse moléculaire :219.26Bisindolylmaleimide VIII Acetic Acid Salt
CAS :Produit contrôlé<p>Applications It is a potent inhibitor of protein kinase C (PKC) activity. Bisindolylmaleimide VIII (Bis VIII) has been previously shown to enhance Fas-mediated apoptosis through a protein kinase C-independent mechanism.<br>References Emery, J., et al.: J. Biol. Chem., 273, 14363 (1998), Wiley, S., et al.: Immunity, 3, 673 (1995), MacFarlane, M., et al.: Biochem. J., 348, 93 (2000),<br></p>Formule :C26H26N4O4Couleur et forme :NeatMasse moléculaire :458.511-(5-Isoquinolinesulfonyl)-2-methylpiperazine Dihydrochloride
CAS :Produit contrôlé<p>Applications A selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases.<br>References Hidaka, H. and Kawamoto, S.: Biochem. and Biophys. Res. Comm., 125, 1, 258 (1984)<br></p>Formule :C14H17N3O2S·2ClHCouleur et forme :NeatMasse moléculaire :364.29O,S-Diethyl Methylphosphonothioate
CAS :Produit contrôlé<p>Stability Moisture Sensitive<br>Applications An inhibitor of cholinesterase.<br>References Berman, H., et al.: J. Biol. Chem., 264, 3951 (1989), Millard, C., et al.: Biochemistry, 37, 237 (1998), Koellner, G., et al.: J. Mol. Biol., 296, 713 (2000),<br></p>Formule :C5H13O2PSCouleur et forme :NeatMasse moléculaire :168.193-Acetyl-11-keto-β-boswellic Acid
CAS :Produit contrôléFormule :C32H48O5Couleur et forme :WhiteMasse moléculaire :512.721-Propan-1,1,2,2,3,3,3-d7-amine
CAS :Produit contrôléFormule :C3H2D7NCouleur et forme :NeatMasse moléculaire :66.15O-(2,4-Dinitrophenyl)hydroxylamine
CAS :<p>Applications O-(2,4-Dinitrophenyl)hydroxylamine is a rapid active-site-directed inhibitor of D-amino acid oxidase; modification results in specific incorporation of an amine group into an accessible nucleophilic residue with concomitant release of 2,4-dinitrophenol.<br>References D'Silva, C., et al.: Biochemi., 25, 5602 (1986),<br></p>Formule :C6H5N3O5Couleur et forme :Brown SolidMasse moléculaire :199.12N-Acetyl-Lys-Octreotide Trifluoroacetic Acid Salt
CAS :<p>Stability Hygroscopic<br>Applications N-Acetyl-Phe-Octreotide is used as reactant/reagent in inhibition of octreotide acylation inside PLGA microspheres by derivatization of amines of peptide with self-immolative protecting group.<br>References Shirangi, M., et al.: Bioconjugate Chem., 27, 576-585 (2016)<br></p>Formule :C51H68N10O11S2·xC2HF3O2Couleur et forme :NeatMasse moléculaire :1061.284Resolvin E1 Sodium Salt
CAS :Produit contrôléFormule :C20H29NaO5Couleur et forme :NeatMasse moléculaire :372.431(5E)-6-(4-Hydroxy-3-methoxyphenyl)-5-hexene-2,4-dione
CAS :Produit contrôlé<p>Applications Curcumin (C838500) and gingerdione derivative. A possible human glyoxalase I inhibitor. Flavor modifier.<br>References Yuan, M. et al.; Bioorg. Med. Chem. 19, 1189 (2011); Ley, J. et al.; J. Agr. Food Chem. 56, 6656 (2008)<br></p>Formule :C13H14O4Couleur et forme :NeatMasse moléculaire :234.25(±)-Procinolol Hydrochloride
CAS :Produit contrôlé<p>Applications (±)-Procinolol is a beta adrenergic receptor antagonist.<br>References Singh, K.: Indian J. Phsiol. Pharmacol., 27, 311 (1983)<br></p>Formule :C15H24ClNO2Couleur et forme :NeatMasse moléculaire :285.81Baohuoside I
CAS :Produit contrôlé<p>Applications Baohuoside I is an inhibitor of cell growth and also is a down-regulator of durvivin and cyclin D1 expression. Used in the treatment of esophageal cancer. Anti-cancer agent.<br>References Lifang, W. et al.: Oncology Rep., 26, 1149 (2011); Jin, X. et al.: Drug Dev. Ind. Pharm., 39, 1421 (2013);<br></p>Formule :C27H30O10Couleur et forme :NeatMasse moléculaire :514.52Raloxifene 4’-β-D-Glucuronide Lithium Salt
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Raloxifene 4’-Glucuronide Lithium Salt is a metabolite of Raloxifene (R099995), a nonsteroidal estrogen receptor mixed agonist/antagonist.<br>References Dodge, J., et al.: Bioorg. Med. Chem. Lett., 7, 993 (1997); Jeong, E., et al.: Drug Metab. Dispos., 33, 785 (2005); Trontelj, J., et al.: Pharmacol. Res., 52, 334 (2005); Oswald, S., et al.: Clin. Pharmacol. Ther., 79 206 (2006)<br></p>Formule :C34H34LiNO10SCouleur et forme :NeatMasse moléculaire :655.644-Amino-5-(bromomethyl)-2-methylpyrimidine Dihydrobromide
CAS :Produit contrôlé<p>Applications A pyrimidine derivative as G protein-coupled receptor kinase (GRK) inhibitor.<br>References Bigham, E., et al.: J. Med. Chem., 35, 1399 (1992), Jansen, M., et al.: Biochem. Pharmacol., 47, 1067 (1994), Hasbi, A., et al.: J. Neurochem., 70, 2129 (1998),<br></p>Formule :C17H17N3O2SCouleur et forme :NeatMasse moléculaire :327.40N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride
CAS :Produit contrôlé<p>Applications Found to have a potent inhibitory action against casein kinase 1 completely with respect to ATP and a much weaker effect on casein kinase 2 and other protein kinases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hidaka, H., et al.: J. of Biol. Chem., 264, 9, 4924 (1989)<br></p>Formule :C11H12ClN3O2S·2ClHCouleur et forme :NeatMasse moléculaire :358.67Retorphan
CAS :Produit contrôlé<p>Applications Retorphan is a powerful and selective inhibitors of neprilysin and is being developed as a therapeutic agent. Retorphan behave as the prodrug of the enantiomers of Thiorphan (T369500).<br>References Monteil, T., et al.: Mini. Rev. Med. Chem., 2, 209 (2002); Roques, B.P., et al.: Nature, 288, 286 (1980); Tiraboschi, G., et al.: Protein Engineering, 12, 2, 141 (1999)<br></p>Formule :C21H23NO4SCouleur et forme :NeatMasse moléculaire :385.48(1R,2R)-2-Fluorocyclopentanamine Hydrochloride
CAS :Produit contrôlé<p>Applications A cyclopentanamine used in the preparation of heterocyclic and aromatic ureas and amides as CEPT inhibitors.<br></p>Formule :C5H11ClFNCouleur et forme :NeatMasse moléculaire :139.61-Deoxy-L-altronojirimycin Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications α-Glycosidase inhibitor.<br>References Jefferies, I., et al.: Bioorg. Med. Chem. Lett., 7, 1171 (1997), Hassan, A., et al.: Carbohydr. Res., 339, 1565 (2004),<br></p>Formule :C6H13NO4·ClHDegré de pureté :>90%Couleur et forme :NeatMasse moléculaire :199.634-Fluorobenzoic Acid-d4
CAS :Produit contrôlé<p>Applications 4-Fluorobenzoic Acid-d4 is used as a reagent in the synthesis of Flurofamide-d4 (F596687); the isotope labelled analog of Fluorofamide (F596685) which is a compound that acts as a urease inhibitor, useful in the treatment of gastritis and irregular urease activity in the urinary tract.<br>References Loes, A. et al.: Lett. App. Microbiol., 58, 31 (2014); Ohta, T.et al.: Biochem. Biophys, Res. Comm., 285, 728 (2001)<br></p>Formule :C7HD4FO2Couleur et forme :NeatMasse moléculaire :144.14tert-Butyl (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)carbamate
CAS :Produit contrôléFormule :C17H30BNO4Couleur et forme :NeatMasse moléculaire :323.24n-Pentyl-d11 chloroformate
CAS :Produit contrôlé<p>Applications n-Pentyl-d11 chloroformate is labelled n-Pentyl chloroformate which can be used to synthesize 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase.<br>References Kim, I., et al.: J. Med. Chem., 47, 2110 (2004); Hammock, B., et al.: PCT Int. Appl. (2006), WO 2006045119 A2 20060427.<br></p>Formule :C6D11ClO2Couleur et forme :NeatMasse moléculaire :161.674-Pyridin-2,3,5,6-d4-ol-d
CAS :Produit contrôlé<p>Applications 4-Pyridin-2,3,5,6-d4-ol-d is one of the azepanone derivatives studies as CGRP receptor antagonists.<br>References Liu, J.: PCT Int. Appl. (2010), WO 2010108103 A1 20100923.<br></p>Formule :C5D5NOCouleur et forme :NeatMasse moléculaire :100.13n-Propyl-2,2,3,3,3-d5-amine Hydrochloride
CAS :Produit contrôlé<p>Applications n-Propyl-2,2,3,3,3-d5-amine Hydrochloride is the hydrochloride salt of 1-Propyl-d5-amine (P833702); the isotope labelled analog of 1-Propylamine (P833700) which is used in the synthesis of pyrimidine derivatives as novel and highly potent PDE4 inhibitors. It is also used in the preparation of fluorenone analogs with DNA topisomerase I inhibitors.<br>References Goto, T. et al.: Bioorg. Med. Chem., 21, 7025 (2013); Lee, C. et al.: Bioorg. Med. Chem. 21, 7125, (2013)<br></p>Formule :C3H5D5ClNCouleur et forme :NeatMasse moléculaire :100.6tert-Butyl 4-Bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate
CAS :Produit contrôléFormule :C18H17BrN2O3Couleur et forme :NeatMasse moléculaire :389.24GW4869 TFA Salt (~90%, ~10% inorganics)
CAS :Produit contrôlé<p>Applications GW4869 is a selective inhibitor of N-SMase.<br>References Lallemand, T., et al.: Arterioscler. Thromb. Vasc. Biol., 38, 1479 (2018); Figuera-Losada, M., et al.: PLoS One, 10, 0124481 (2015)<br></p>Formule :C30H28N6O2·xC2HF3O2Couleur et forme :NeatMasse moléculaire :504.58 + x(114.02)N-Fmoc-glycine-d2
CAS :Produit contrôlé<p>Applications Isotope labelled N-Fmoc-glycine is an N-Fmoc-protected form of Glycine (G615990). Glycine is a nonessential amino acid that acts as an inhibitory neyrotransmitter in the vertebrate central nervous system. Glycine also posesses cytoprotective against oxidant damage in the kidney.<br>References Eulenberg, V., et al.: Trend. Biochem. Sci., 30, 325 (2005); Gundersen, R., et al.: Acta Anaesth. Scand., 49, 1108 (2005); Lockart, R. & Eagle, H.: Science, 129, 252 (1959); Sogabe, K., et al.: Kidn. Int., 50, 845 (1996)<br></p>Formule :C17H13D2NO4Couleur et forme :NeatMasse moléculaire :299.32Ethyl Palmitate-d31
CAS :Produit contrôlé<p>Applications A labelled fatty acid found in Amaranth oil; it shows inhibitory activity.<br>References Fidler, N., et al.: J. Lipid Res., 41, 1376 (2000), Yang, T., et al.: Food Chem., 80, 473 (2003), Gamel, T., et al.: J. Food Lipids, 14, 323 (2007),<br></p>Formule :C18H5D31O2Couleur et forme :NeatMasse moléculaire :315.671-Propyl-d5-amine
CAS :Produit contrôlé<p>Applications 1-Propyl-d5-amine is labelled 1-Propylamine (P833700) which is used in the synthesis of pyrimidine derivatives as novel and highly potent PDE4 inhibitors. It is also used in the preparation of fluorenone analogs with DNA topisomerase I inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C3H4D5NCouleur et forme :NeatMasse moléculaire :64.14(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications (3R,5S,6E)-7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent.<br>References Suzukim M., et al.: Bioorg. Med. Chem., 9, 2977 (1999); Yen, H., et al.: J. Clin. Invest., 98, 1253 (1996); Zou, Y., et al.: J. Biol. Chem., 274, 9760 (1999); Sun, X., et al.: Cancer Res., et al.: 61, 3382 (2001); Ladas, E.J., et al.: Clin. Oncol., 22, 517 (2004);<br></p>Formule :C25H24NNaO4Couleur et forme :NeatMasse moléculaire :425.45rac-1,2-Dioctanoyl-3-Chloropropanediol
CAS :Produit contrôlé<p>Stability Moisture Sensitive<br>Applications rac-1,2-Dioctanoyl-3-Chloropropanediol was studied for its ability to act as an inhibitor of protein kinase C.<br>References Briggs, Josie C., et al.: Carbohydrate Res., 234, 23-35 (1992)<br></p>Formule :C19H35ClO4Couleur et forme :NeatMasse moléculaire :362.93N-(n-Butyl)phosphoric Triamide
CAS :<p>Applications N-Alkyl phosphoric triamide useful as urease inhibitors.<br></p>Formule :C4H14N3OPCouleur et forme :White SolidMasse moléculaire :151.153-Amino-N-(Tertbutylbenzenesulfonamide
CAS :Produit contrôlé<p>Applications 3-Amino-N-(Tert-Butyl)Benzenesulfonamide (cas# 608523-94-0) is a useful research chemical.<br></p>Formule :C10H16N2O2SCouleur et forme :NeatMasse moléculaire :228.31(E)-a-Hydroxy Tamoxifen
CAS :Produit contrôlé<p>Applications A metabolite of the chemotherapeutic drug Tamoxifen (T006000). Exhibits a more potent estrogen agonist/antagonist activity than the parent drug. Also active as an intramembranous inhibitor of lipid peroxidation.<br>References Kupfer, D., et al.: Cancer Res., 54, 3140 (1994), Custodio, J.B.A., et al.: Biochem. Pharmacol., 47, 1989 (1994),<br></p>Formule :C26H29NO2Couleur et forme :NeatMasse moléculaire :387.51Valtrate
CAS :Produit contrôlé<p>Applications Valtrate is a Rev-transport inhibitor with anti-HIV activity from Valerianae Radix.<br>References Murakami, N., et al.: Bioorg. Med. Chem. Lett., 12, 2807 (2002); Watanabe, K., et al.: Drug Discoveries Ther., 5, 26 92011)<br></p>Formule :C22H30O8Couleur et forme :Light Brown To Dark YellowMasse moléculaire :422.47A 83-01
CAS :Produit contrôlé<p>Stability Moisture Sensitive<br>Applications A 83-01 is a selective inhibitor of TGF-β type I receptor. A 83-01 treatment increases tumor permeability.<br>References Minowa, T. et al.: British. J. Canc., 101, 1884 (2009)<br></p>Formule :C25H19N5SCouleur et forme :Off-WhiteMasse moléculaire :421.52(3R)-1-Methyl-3-Pyrrolidinemethanol
CAS :Produit contrôlé<p>Applications (3R)-1-Methyl-3-Pyrrolidinemethanol is a reactant in the synthesis of heterocyclic carboxylic acid amides with potential as PDK1 inhibitors.<br></p>Formule :C6H13NOCouleur et forme :NeatMasse moléculaire :115.17N-Des-2-methylpropan-2-ol Docetaxel
Produit contrôléFormule :C39H45NO13Couleur et forme :NeatMasse moléculaire :735.77356α-Methylandrost-4-ene-3,17-dione
CAS :Produit contrôléFormule :C20H28O2Couleur et forme :NeatMasse moléculaire :300.44B-[2-(Methylamino)-4-pyridinyl]boronic Acid Hydrochlroide Hydrate
CAS :Produit contrôlé<p>Applications B-[2-(Methylamino)-4-pyridinyl]boronic Acid Hydrochlroide, is used to prepare novel selective thiazoleacetic acids as CRTH2 antagonists.<br>References Grimstrup, M., et al.: Bioorg. Med. Chem. Lett., 20, 1181 (2010)<br></p>Formule :C6H9BN2O2•HCl•xH2OCouleur et forme :NeatMasse moléculaire :151.963646N-(4'-Cyano[1,1'-biphenyl]-4-yl)-N'-[4-(3H-imidazo[4,5-b]pyridin-7-yl)phenyl] Urea
CAS :Produit contrôlé<p>Applications N-(4'-Cyano[1,1'-biphenyl]-4-yl)-N'-[4-(3H-imidazo[4,5-b]pyridin-7-yl)phenyl] Urea, is a highly selective inhibitor of cytochrome P450 3A4, which is one of the most important enzymes involved in the metabolism of pharmaceuticals and xenobiotics.<br>References Song, X., et al.: Bio. Med. Chem. Lett., 22, 1611(2012);<br></p>Formule :C26H18N6OCouleur et forme :NeatMasse moléculaire :430.464-Hydroxypiperidine-D4
CAS :Produit contrôlé<p>Applications 4-Hydroxypiperidine-D4 is an isotope labelled form of 4-Hydroxypiperidine (H950845), a reagent for the synthesis of acridine (A190900) derivatives and fibrinogen receptor antagonists.<br>References Yang, D. et al.: Macromol., 35, 5304 (2002); Harrison, R.J. et al.: Bioorg. Med. Chem. Lett., 9, 2463 (1999);<br></p>Formule :C5H7D4NOCouleur et forme :NeatMasse moléculaire :105.17Olorofim
CAS :Produit contrôléFormule :C28H27FN6O2Couleur et forme :Off-WhiteMasse moléculaire :498.551Ethyl 2-[[(3aR,4S,6R,6aS)-6-[(Benzyloxycarbonyl)amino]-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]acetate
CAS :Produit contrôléFormule :C20H27NO7Couleur et forme :NeatMasse moléculaire :393.43(-)-Epigallocatechin Gallate-d3/d4
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Labelled (-)-Epigallocatechin Gallate, a tumor-inhibiting constituent of green tea. (-)-Epigallocatechin Gallate alters the cleavage of amyloid precursor protein, decreasing production of amaloid-ß and amaloid plaques in mice.<br>References Yamane, T. et al.: Cancer Res., 55, 2081 (1995); Tan, J. et al.: J. Neurosci. 25, 8807 (2005);<br></p>Formule :C22D3H15O11Couleur et forme :NeatMasse moléculaire :461.39(-)-Huperzine A-d6 (Major)
CAS :Produit contrôléFormule :C15H11D7N2OCouleur et forme :NeatMasse moléculaire :248.35K252a
CAS :Produit contrôlé<p>Applications K252a is a protein kinase inhibitor. It is an analogue of staurosporine (S685000). It shows potent antitumor activity but no antimicrobial activity in vitro, or in vivo toxicity in rodents.<br>References Kase, H., et al.: J. Antibiot., 39, 1059 (1986); Yasuzawa, T., et al.; J. Antibiot., 39, 1072 (1986)<br></p>Formule :C27H21N3O5Couleur et forme :NeatMasse moléculaire :467.47N-(7-Oxa-9,9,9-trifluorononyl)deoxynojirimycin
CAS :Produit contrôléFormule :C14H26F3NO5Couleur et forme :NeatMasse moléculaire :345.362-Methylbutyryl-d9 Chloride
CAS :Produit contrôléFormule :C5D9ClOCouleur et forme :NeatMasse moléculaire :129.63N-Butyldeoxymannojirimycin Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications An extremely potent and selective a-D-mannosidase inhibitor.<br></p>Formule :C10H21NO4·ClHCouleur et forme :NeatMasse moléculaire :255.74D,L-Alanosine Sodium Salt
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications D,L-Alanosine is an antibiotic substance from the fermentation of Streptomyces alanosinicus. An experimental insect reproduction inhibitor.<br>References Gale, et al.: Biochem. Pharmacol., 17, 363 (1968); Kenaga, E.E.: J. Econ. Entomol., 62, 1006 (1969); Matsumoto, S., et al.: Agric. Biol. Chem., 48, 827 (1984)<br></p>Formule :C3H6N3NaO4Couleur et forme :NeatMasse moléculaire :171.09rac-syn-Ezetimibe
Produit contrôlé<p>Applications rac-syn-Ezetimibe is an analog of Ezetimibe (E975000); an antihyperlipoproteinemic and a cholesterol absorption inhibitor.<br>References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997); van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>Formule :C24H21F2NO3Couleur et forme :NeatMasse moléculaire :409.434”DeFluoro-4”methyl-Ezetimibe
CAS :Produit contrôléFormule :C25H24FNO3Couleur et forme :NeatMasse moléculaire :405.46Homoveratrylamine-d10 Hydrochloride
CAS :Produit contrôlé<p>Applications Labelled 2-(3,4-Dimethoxyphenyl)-N-methylethylamine (D470710, free amine) which is a methylated metabolite of Dopamine (D533780); a potent inhibitor of brain mitochondrial respiration used in Parkinson’s disease studies.<br>References Gluck, M.R. et al.: J. Neurochem., 91, 788 (2004); Charlton, C.G. et al.: Life Sci., 66, 2159 (2000);<br></p>Formule :C10H6D10ClNO2Couleur et forme :NeatMasse moléculaire :227.752,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic Acid
CAS :Produit contrôlé<p>Applications This compound is used in the synthesis of novel lactate dehydrogenase A inhibitors.This compound is suitable for lactate dehydrogenase (LDH) related research.<br>References Ward, R.A. et al.: J. Med. Chem., 55, 3258 (2012);<br></p>Formule :C22H22O4Couleur et forme :NeatMasse moléculaire :350.41Edrophonium-d5 Chloride
CAS :Produit contrôléFormule :C10D5H11NO·ClCouleur et forme :NeatMasse moléculaire :206.72Diethyl-d10 Carbonate
CAS :Produit contrôlé<p>Applications Diethyl-d10 Carbonate is deuterium labelled Diethyl Carbonate (D444000), which is used in the synthesis of 2-oxooxazolidines as antibacterials. It can also be used to synthesize donepezil/huperzine fragments as acetylcholinesterase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gregory, W. et al.: J. Med. Chem., 32, 1673 (1989); Bioorg. Med. Chem., 21, 676 (2013)<br></p>Formule :C5D10O3Couleur et forme :NeatMasse moléculaire :128.19Methanesulfonyl Chloride-d3,13C
CAS :Formule :C2H3ClO2SCouleur et forme :Colourless OilMasse moléculaire :118.56
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