EGFR
Les inhibiteurs du récepteur du facteur de croissance épidermique (EGFR) sont des composés qui bloquent la signalisation de l'EGFR, un récepteur souvent surexprimé dans divers cancers et qui joue un rôle crucial dans l'angiogenèse. Les inhibiteurs de l'EGFR sont utilisés pour prévenir la croissance tumorale et les métastases en perturbant les voies qui favorisent la formation de vaisseaux sanguins dans les tumeurs. Ces inhibiteurs sont largement utilisés dans la recherche et le traitement du cancer. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de l'EGFR de haute qualité pour soutenir vos recherches en oncologie et angiogenèse.
572 produits trouvés pour "EGFR"
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PP2
CAS :<p>PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.</p>Formule :C15H16ClN5Degré de pureté :98% - 98.21%Couleur et forme :White SolidMasse moléculaire :301.77Tyrphostin AG30
CAS :<p>Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.</p>Formule :C10H7NO4Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :205.17PD-161570
CAS :<p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>Formule :C26H35Cl2N7ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :532.51Lazertinib
CAS :<p>Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.</p>Formule :C30H34N8O3Degré de pureté :98.7% - 99.90%Couleur et forme :SolidMasse moléculaire :554.64Tyrphostin A1
CAS :<p>Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .</p>Formule :C11H8N2ODegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :184.19WZ4002
CAS :<p>WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.</p>Formule :C25H27ClN6O3Degré de pureté :97.51%Couleur et forme :SolidMasse moléculaire :494.97MAZ51
CAS :<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Formule :C21H18N2ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :314.38Gefitinib-based PROTAC 3
CAS :<p>Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).</p>Formule :C47H57ClFN7O8SDegré de pureté :97.29% - 98.25%Couleur et forme :SolidMasse moléculaire :934.51Dacomitinib hydrate
CAS :<p>Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of</p>Formule :C24H27ClFN5O3Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :487.96Almonertinib
CAS :<p>Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.</p>Formule :C30H35N7O2Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :525.64G5-7
CAS :<p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>Formule :C22H19F2NO3Degré de pureté :97.3%Couleur et forme :SolidMasse moléculaire :383.39AG-494
CAS :<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Formule :C16H12N2O3Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :280.28Neratinib
CAS :<p>Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.</p>Formule :C30H29ClN6O3Degré de pureté :96.17% - 99.85%Couleur et forme :SolidMasse moléculaire :557.04Osimertinib mesylate
CAS :<p>Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.</p>Formule :C29H37N7O5SDegré de pureté :99.46% - >99.99%Couleur et forme :SolidMasse moléculaire :595.71RG13022
CAS :<p>RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).</p>Formule :C16H14N2O2Degré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :266.29RG14620
CAS :<p>RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.</p>Formule :C14H8Cl2N2Degré de pureté :99.82% - 99.87%Couleur et forme :SolidMasse moléculaire :275.13Allitinib tosylate
CAS :<p>Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.</p>Formule :C31H26ClFN4O5SDegré de pureté :98.46% - 98.68%Couleur et forme :SolidMasse moléculaire :621.08(S)-Sunvozertinib
CAS :<p>(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.</p>Formule :C29H35ClFN7O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :584.08BI-4020
CAS :<p>BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.</p>Formule :C30H38N8O2Degré de pureté :97.21% - >99.99%Couleur et forme :SolidMasse moléculaire :542.68Avitinib
CAS :<p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>Formule :C26H26FN7O2Degré de pureté :99.81% - >99.99%Couleur et forme :SolidMasse moléculaire :487.53Avitinib maleate
CAS :<p>Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.</p>Formule :C30H30FN7O6Degré de pureté :98% - 99.74%Couleur et forme :SolidMasse moléculaire :603.61Alflutinib mesylate
CAS :<p>Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.</p>Formule :C29H35F3N8O5SDegré de pureté :97.94% - 99.63%Couleur et forme :SolidMasse moléculaire :664.7(E)-AG 556
CAS :<p>AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.</p>Formule :C20H20N2O3Degré de pureté :99.93%Couleur et forme :Light Yellow PowderMasse moléculaire :336.38NSC 228155
CAS :<p>NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.</p>Formule :C11H6N4O4SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :290.25Afatinib Dimaleate
CAS :<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Formule :C32H33ClFN5O11Degré de pureté :98.11% - 99.87%Couleur et forme :SolidMasse moléculaire :718.08AZ-5104
CAS :<p>AZ5104 is a potent EGFR inhibitor.</p>Formule :C27H31N7O2Degré de pureté :98.40% - 99.59%Couleur et forme :Solid PowderMasse moléculaire :485.58Dacomitinib
CAS :<p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>Formule :C24H25ClFN5O2Degré de pureté :99.4% - 99.72%Couleur et forme :SolidMasse moléculaire :469.94Tyrphostin A9
CAS :<p>Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor</p>Formule :C18H22N2ODegré de pureté :98.21% - 99.87%Couleur et forme :Yellow SolidMasse moléculaire :282.38Poziotinib hydrochloride
CAS :<p>Oral poziotinib HCl targets EGFR/HER mutants, inhibiting cancer cell growth.</p>Formule :C23H22Cl3FN4O3Degré de pureté :99.69% - 99.81%Couleur et forme :SolidMasse moléculaire :527.8PP 3
CAS :<p>PP 3 is a Negative control for the Src kinase inhibitor PP 2</p>Formule :C11H9N5Degré de pureté :98.61%Couleur et forme :Whit To Off-White SolidMasse moléculaire :211.22Osimertinib
CAS :<p>Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.</p>Formule :C28H33N7O2Degré de pureté :99.32% - >99.99%Couleur et forme :SolidMasse moléculaire :499.61Butein
CAS :<p>Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.</p>Formule :C15H12O5Degré de pureté :98.76% - >99.99%Couleur et forme :SolidMasse moléculaire :272.25PD158780
CAS :<p>PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.</p>Formule :C14H12BrN5Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :330.18β-Hydroxyisovalerylshikonin
CAS :<p>Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor</p>Formule :C21H24O7Degré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :388.41TAS6417
CAS :<p>Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>Formule :C23H20N6ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :396.44PD153035 hydrochloride
CAS :<p>PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.</p>Formule :C16H15BrClN3O2Degré de pureté :99.39% - ≥95%Couleur et forme :SolidMasse moléculaire :396.67EAI045
CAS :<p>EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.</p>Formule :C19H14FN3O3SDegré de pureté :98.00% - 99.12%Couleur et forme :SolidMasse moléculaire :383.4AZ7550
CAS :<p>AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>Formule :C27H31N7O2Degré de pureté :97.07% - 99.75%Couleur et forme :SolidMasse moléculaire :485.58Epidermal Growth Factor
CAS :<p>EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.</p>Formule :C270H401N73O83S7Degré de pureté :97.17%Couleur et forme :SolidMasse moléculaire :6222CP-380736
CAS :<p>CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.</p>Formule :C14H18N2O5Degré de pureté :99.68%Couleur et forme :White To Off-White SolidMasse moléculaire :294.3Tyrphostin 23
CAS :<p>Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.</p>Formule :C10H6N2O2Degré de pureté :99.7% - 99.86%Couleur et forme :Yellow-Tan SolidMasse moléculaire :186.17EGFR-IN-12
CAS :<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Formule :C21H18F3N5ODegré de pureté :98.3% - 99.76%Couleur et forme :SolidMasse moléculaire :413.4ALK-IN-1
CAS :<p>ALK-IN-1 is a potent ALK inhibitor, demonstrating the ability to overcome Crizotinib resistance mediated by an L1196M mutation.</p>Formule :C26H34ClN6O2PDegré de pureté :99.74% - 99.80%Couleur et forme :SolidMasse moléculaire :529.01Zorifertinib
CAS :<p>Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.</p>Formule :C22H23ClFN5O3Degré de pureté :98.20% - 99.36%Couleur et forme :White To Off-White SolidMasse moléculaire :459.9MTX-211
CAS :<p>MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.</p>Formule :C20H14Cl2FN5O2SDegré de pureté :97.6% - >99.99%Couleur et forme :SolidMasse moléculaire :478.33Desmethyl Erlotinib hydrochloride
CAS :<p>Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor.</p>Formule :C21H21N3O4·HClDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :415.87AG 555
CAS :<p>AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.</p>Formule :C19H18N2O3Degré de pureté :98.02% - 99.94%Couleur et forme :SolidMasse moléculaire :322.36WHI-P258
CAS :<p>WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.</p>Formule :C16H15N3O2Degré de pureté :99.66% - 99.92%Couleur et forme :SolidMasse moléculaire :281.31AG-1478
CAS :<p>AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.</p>Formule :C16H14ClN3O2Degré de pureté :99.03% - 99.71%Couleur et forme :SolidMasse moléculaire :315.75Desmethyl Erlotinib
CAS :<p>Desmethyl Erlotinib (CP-473420) is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).</p>Formule :C21H21N3O4Degré de pureté :97.92% - 98.62%Couleur et forme :SolidMasse moléculaire :379.41Tesevatinib
CAS :<p>Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>Formule :C24H25Cl2FN4O2Degré de pureté :97.89% - 98.66%Couleur et forme :SolidMasse moléculaire :491.39EBE-A22
CAS :<p>EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.</p>Formule :C17H16BrN3O2Degré de pureté :99.087% - 99.88%Couleur et forme :SolidMasse moléculaire :374.23Pelitinib
CAS :<p>Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).</p>Formule :C24H23ClFN5O2Degré de pureté :98.37% - 99.84%Couleur et forme :Off-White SolidMasse moléculaire :467.92WZ-3146
CAS :<p>WZ3146: EGFR(L858R/E746_A750) inhibitor, IC50=2 nM, selective, doesn't block ERBB2(T798I).</p>Formule :C24H25ClN6O2Degré de pureté :97.15%Couleur et forme :SolidMasse moléculaire :464.95CZC-8004
CAS :<p>CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.</p>Formule :C17H16FN5Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :309.34CNX-2006
CAS :<p>CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.</p>Formule :C26H27F4N7O2Degré de pureté :98.85% - 99.16%Couleur et forme :SolidMasse moléculaire :545.53Sapitinib
CAS :<p>Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib or</p>Formule :C23H25ClFN5O3Degré de pureté :98.89% - 99.83%Couleur et forme :SolidMasse moléculaire :473.93Olmutinib
CAS :<p>Olmutinib is an oral mutant-specific EGFR inhibitor for cancer treatment with potential lower toxicity.</p>Formule :C26H26N6O2SDegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :486.59Cyasterone
CAS :<p>Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising</p>Formule :C29H44O8Degré de pureté :99.32% - 99.70%Couleur et forme :SolidMasse moléculaire :520.65Leptomycin B
CAS :<p>Leptomycin B: potent CRM1 inhibitor, blocks protein nuclear export and cell cycle, antifungal, modifies cysteine.</p>Formule :C33H48O6Degré de pureté :97.10% - 99.04%Couleur et forme :White Crystalline SolidMasse moléculaire :540.73Genistein
CAS :<p>Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.</p>Formule :C15H10O5Degré de pureté :98.22% - 99.64%Couleur et forme :Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMasse moléculaire :270.24Rostafuroxin
CAS :<p>Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.</p>Formule :C23H34O4Degré de pureté :99.08% - >99.99%Couleur et forme :SolidMasse moléculaire :374.51Almonertinib mesylate
CAS :<p>Almonertinib mesylate: EGFR tyrosine kinase inhibitor, targets EGFR-mutant non-small cell lung cancer.</p>Formule :C31H39N7O5SDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :621.75(Rac)-JBJ-04-125-02
CAS :<p>(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.</p>Formule :C29H26FN5O3SDegré de pureté :97.57%Couleur et forme :SolidMasse moléculaire :543.61Mobocertinib
CAS :<p>Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent</p>Formule :C32H39N7O4Degré de pureté :99.47% - 99.97%Couleur et forme :SolidMasse moléculaire :585.7CUDC-101
CAS :<p>CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50s of 4.4, 2.4 and 15.7 nM, respectively.</p>Formule :C24H26N4O4Degré de pureté :95.76% - 99.17%Couleur et forme :SolidMasse moléculaire :434.49Afatinib
CAS :<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formule :C24H25ClFN5O3Degré de pureté :98.56% - 99.9%Couleur et forme :Off-White SolidMasse moléculaire :485.94PD153035
CAS :<p>PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,</p>Formule :C16H14BrN3O2Degré de pureté :98.47% - 99.29%Couleur et forme :SolidMasse moléculaire :360.21Nazartinib
CAS :<p>Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (</p>Formule :C26H31ClN6O2Degré de pureté :98.63% - ≥95%Couleur et forme :Solid PowderMasse moléculaire :495.02PD-089828
CAS :<p>PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).</p>Formule :C18H18Cl2N6ODegré de pureté :97.39%Couleur et forme :SolidMasse moléculaire :405.28Gefitinib hydrochloride
CAS :<p>Obtustatin triacetate is an integrin derived from the venom of Vipera lebetina obtusa and is an α1β1 integrin and in vivo angiogenesis inhibitor.</p>Formule :C22H25Cl2FN4O3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :483.36Cavutilide
CAS :<p>Cavutilide has antiarrhythmic activity, inhibits hERG K(+) channels, and can be used to study heart failure and persistent atrial fibrillation.</p>Formule :C22H26FN3O3Degré de pureté :99.82% - 99.85%Couleur et forme :SolidMasse moléculaire :399.458Naquotinib mesylate
CAS :<p>Naquotinib mesylate (ASP8273 (mesylate)) is an orally available, mutant-selective and irreversible inhibitor of EGFR(iC50s of 8-33 nM and 230 nM for toward EGFR</p>Formule :C31H46N8O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :658.81Almonertinib hydrochloride
CAS :<p>Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation.</p>Formule :C30H36ClN7O2Degré de pureté :98.01% - 98.12%Couleur et forme :SolidMasse moléculaire :562.1Canertinib dihydrochloride
CAS :<p>Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and</p>Formule :C24H27Cl3FN5O3Degré de pureté :99.13% - >99.99%Couleur et forme :SolidMasse moléculaire :558.86BMS-690514
CAS :<p>BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.</p>Formule :C19H24N6O2Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :368.43Ponezumab
CAS :<p>Ponezumab (PF-04360365), a humanized IgG2 antibody, lowers Aβ in the CNS & boosts mice memory. Used in Alzheimer's research.</p>Couleur et forme :LiquidSerclutamab
CAS :<p>Serclutamab, a humanized chimeric monoclonal antibody of the IgG1-κ isotype, selectively targets the epidermal growth factor receptor (EGFR).</p>Degré de pureté :98%Couleur et forme :LiquidZalutumumab
CAS :<p>Zalutumumab is a high-affinity fully human monoclonal antibody ,the extracellular domain of the EGFR squamous cell carcinoma of the head and neck (SCCHN).</p>Degré de pureté :95%Couleur et forme :LiquidElgemtumab
CAS :<p>Elgemtumab (LJM716) is a fully humanised monoclonal antibody targeting HER3/ERBB3, acting as an antagonist to block HER3/Akt phosphorylation antitumour.</p>Degré de pureté :95%Couleur et forme :LiquidZanidatamab
CAS :<p>Zanidatamab (ZW25) is a bispecific, humanized monoclonal antibody that targets two distinct epitopes (ECD2 and ECD4) of the HER2 receptor, exhibiting anti-tumor</p>Couleur et forme :LiquidAnbenitamab
CAS :<p>Anbenitamab (KN-026) is a bispecific HER2 antibody for metastatic breast cancer research, blocking HER2 pathways and mediating ADCC.</p>Couleur et forme :LiquidBecotatug
CAS :<p>Becotatug (JMT-101) is an IgG1 antibody that targets EGFR and can be conjugated to Afatinib and Osimertinib, functioning as a synthetic antibody-drug conjugate</p>Degré de pureté :95% - 95%Couleur et forme :LiquidDepatuxizumab
CAS :<p>Depatuxizumab is a humanised monoclonal antibody targeting EGFR with blood-brain barrier (BBB) permeability, inhibit tumor growth,GBM,SCCHN.</p>Degré de pureté :95%Couleur et forme :LiquidFutuximab
CAS :<p>Futuximab, a chimeric monoclonal antibody, targets distinct epitopes on the epidermal growth factor receptor (EGFR), exhibiting antineoplastic activity [1].</p>Degré de pureté :95% - 95%Couleur et forme :LiquidIzalontamab
CAS :<p>Izalontamab (SI-B001) is a bispecific EGFR/HER3 monoclonal antibody that binds to both EGFR×EGFR homodimers and EGFR×HER3 heterodimers.</p>Degré de pureté :95%+ - 95%+Couleur et forme :LiquidImgatuzumab
CAS :<p>Imgatuzumab (RG 7160) is a humanized anti-EGFR monoclonal antibody and immunomodulator for cancer research.</p>Couleur et forme :LiquidMasse moléculaire :145.0 (kDa)lavendustin A
CAS :<p>lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.</p>Formule :C21H19NO6Degré de pureté :98%Couleur et forme :Off-White SolidMasse moléculaire :381.38ZM323881 hydrochloride
CAS :<p>ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.</p>Formule :C22H19ClFN3O2Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :411.86Icotinib
CAS :<p>Icotinib (Conmana) is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.</p>Formule :C22H21N3O4Degré de pureté :99.76% - 99.94%Couleur et forme :SolidMasse moléculaire :391.42IGF-1R modulator 1
CAS :<p>IGF-1Rmodulator 1 (Example 5) is an IGF-1R modulator featuring an EC50 of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), and 0.39 μM (TrkB). This compound is useful in research on diseases characterized by impaired signaling of neurotrophic and/or other trophic factors, such as Alzheimer's disease.</p>Formule :C22H17N3O4Couleur et forme :SolidMasse moléculaire :387.39TAK-285
CAS :<p>TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.</p>Formule :C26H25ClF3N5O3Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :547.96Icotinib Hydrochloride
CAS :<p>Icotinib Hydrochloride, an oral EGFR inhibitor (BPI-2009H), may halt cancer growth by blocking EGFR signaling.</p>Formule :C22H22ClN3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :427.88Limertinib
CAS :<p>Limertinib (ASK120067) is a EGFR tyrosine kinase inhibitor targeting EGFR T790M, applicable for the study of non-small cell lung cancer.</p>Formule :C29H32ClN7O2Degré de pureté :97.44%Couleur et forme :SolidMasse moléculaire :546.06EGFR/HER2-IN-9
CAS :<p>EGFR/HER2-IN-9, a compound inhibiting both EGFR and HER2, demonstrates potency with IC50 values of 3.2 nM for EGFR, 14 nM for HER2, and 8.3 nM against the EGFR</p>Formule :C25H25ClFN5O4Couleur et forme :SolidMasse moléculaire :513.95EGFR/C797S-IN-1
CAS :<p>EGFR/C797S-IN-1: Potent EGFR-C797S inhibitor, IC50 of 0.128 µM, dose-dependent p-EGFR suppression, anti-tumor properties.</p>Formule :C28H30N4O3Couleur et forme :SolidMasse moléculaire :470.56EAI001
CAS :<p>EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.</p>Formule :C19H15N3O2SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :349.41EGFR-IN-63
CAS :<p>EGFR- IN-63 is an EGFR inhibitor with an IC50 value of 0.096 μM. EGFR- IN-63 exhibited anticancer effects on MCF-7 cells (IC50: 2.49 μM).</p>Formule :C20H12BrN5SCouleur et forme :SolidMasse moléculaire :434.31BIBX 1382 Dihydrochloride
CAS :<p>BIBX 1382 Dihydrochloride blocks Lassa/Ebola entry, aids in studying virus-host interactions, and hints at kinase targets for therapy.</p>Formule :C18H21Cl3FN7Couleur et forme :SolidMasse moléculaire :460.76(E/Z)-CP-724714
CAS :<p>(E/Z)-CP-724714, comprising racemic mixtures of (E)-CP-724714 and (Z)-CP-724714 isomers, is a potent, selective, and orally active inhibitor of ErbB2 (HER2)[1].</p>Formule :C27H27N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.54
