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Thrombine

Thrombine

Les inhibiteurs de la thrombine sont des composés qui bloquent la thrombine, une enzyme impliquée dans le processus de coagulation sanguine, qui joue également un rôle dans la promotion de l'angiogenèse. La thrombine peut stimuler la formation de nouveaux vaisseaux sanguins dans les tumeurs, favorisant ainsi leur croissance et leurs métastases. En inhibant la thrombine, ces composés peuvent réduire l'angiogenèse et la progression tumorale. Les inhibiteurs de la thrombine sont importants à la fois dans la recherche sur le cancer et dans l'étude des maladies vasculaires. Chez CymitQuimica, nous offrons une sélection d'inhibiteurs de la thrombine de haute qualité pour soutenir vos recherches en hémostase, oncologie et angiogenèse.

47 produits trouvés pour "Thrombine"

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  • Dabigatran etexilate

    CAS :
    <p>Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.</p>
    Formule :C34H41N7O5
    Degré de pureté :98.19% - 99.98%
    Couleur et forme :White Powder
    Masse moléculaire :627.73
  • Dabigatran ethyl ester hydrochloride

    CAS :
    <p>Dabigatran prevents blood clots, inhibiting NQO2 and thrombin with IC50 0.8 μM.</p>
    Formule :C27H30ClN7O3
    Degré de pureté :99.65%
    Couleur et forme :Solid
    Masse moléculaire :536.03
  • H-Gly-Arg-pNA dihydrochloride

    CAS :
    <p>H-Gly-Arg-pNA 2HCl, a peptide, binds 1,2 thrombin; colorimetric quantification at 405 nm indicates thrombin activity.</p>
    Formule :C14H23Cl2N7O4
    Degré de pureté :99.14%
    Couleur et forme :Solid
    Masse moléculaire :424.28
  • Metolazone

    CAS :
    <p>Metolazone (SR-720-22) is a quinazoline-sulfonamide derived diuretic that inhibits sodium chloride symporters.</p>
    Formule :C16H16ClN3O3S
    Degré de pureté :98.14% - 98.5%
    Couleur et forme :Crystals From Ethanol Solid
    Masse moléculaire :365.83
  • Befovacimab

    CAS :
    <p>Befovacimab, a human IgG2 antibody, targets TFPI for hemophilia A/B research.</p>
    Couleur et forme :Liquid
  • PM 102

    CAS :
    <p>Peptide that reverses the anticoagulant effect of heparin. Potently binds heparin (Kd = 36 nM in vitro).</p>
    Formule :C235H425N111O64
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :5830
  • Thrombin (MW 37kDa)

    CAS :
    <p>Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.</p>
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :37kDa
  • Ichorcumab

    CAS :
    <p>Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.</p>
    Couleur et forme :Liquid
  • Protease Inhibitor Library


    <p>A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;</p>
    Couleur et forme :Odour Solid
  • Fibrinopeptide B, human

    CAS :
    <p>Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.</p>
    Formule :C66H93N19O25
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :1552.56
  • Sulodexide

    CAS :
    <p>Sulodexide is an orally administered combination of glycosaminoglycans, consisting of low molecular weight heparin (80%) and dermatan sulfate (20%). It demonstrates antithrombotic properties by interacting with antithrombin III (AT III) and heparin cofactor II (HC II), and by inhibiting thrombin formation. Additionally, sulodexide enhances profibrinolytic activity by releasing tissue plasminogen activator (tPA). It also offers endothelial protection, possesses anti-inflammatory effects, and alleviates chronic venous disease.</p>
    Couleur et forme :Solid
  • Platelet aggregation-IN-1


    <p>Platelet aggregation-IN-1 (Compound 10e) acts as an inhibitor of platelet aggregation and can achieve complete (100%) inhibition of thrombin-induced platelet aggregation at a concentration of 50 μM.</p>
    Formule :C18H13N3O4
    Masse moléculaire :335.09061
  • Thrombin inhibitor 13


    <p>Thrombin inhibitor 13 (Compound 13a) acts as a covalent reversible inhibitor of thrombin (thrombin, FIIa) with an IC50 of 0.7 nM. This compound prolongs activated partial thromboplastin time (aPTT) and prothrombin time (PT), demonstrating both antithrombotic and anticoagulant properties.</p>
    Formule :C16H17ClN6OS
    Couleur et forme :Solid
    Masse moléculaire :376.864
  • Anti-Coagulation Factor II Antibody (8M286)


    <p>Anti-Coagulation Factor II Antibody (8M286) is a Rabbit antibody targeting Coagulation Factor II. Anti-Coagulation Factor II Antibody (8M286) can be used in ELISA.</p>
    Couleur et forme :Odour Liquid
  • Anti-Coagulation Factor II Antibody (2P591)


    <p>Anti-Coagulation Factor II Antibody (2P591) is a Rabbit antibody targeting Coagulation Factor II. Anti-Coagulation Factor II Antibody (2P591) can be used in WB.</p>
    Couleur et forme :Odour Liquid
  • Coagulation Factor II Protein, Rat, Recombinant (His)


    <p>Coagulation Factor II Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Couleur et forme :Lyophilized Powder
    Masse moléculaire :69.5 kDa (predicted)
  • Coagulation Factor II Protein, Mouse, Recombinant (His)


    <p>Coagulation Factor II Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Couleur et forme :Lyophilized Powder
    Masse moléculaire :69.3 kDa (predicted); 85 kDa (reducing conditions)
  • Dabigatran ethyl ester

    CAS :
    <p>Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.</p>
    Formule :C27H29N7O3
    Degré de pureté :99.98%
    Couleur et forme :Solid
    Masse moléculaire :499.56
  • Ximelagatran

    CAS :
    <p>Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.</p>
    Formule :C24H35N5O5
    Degré de pureté :95.48% - 99.60%
    Couleur et forme :Solid
    Masse moléculaire :473.57
  • Dabigatran Etexilate Mesylate

    CAS :
    <p>Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.</p>
    Formule :C34H41N7O5·CH4O3S
    Degré de pureté :99.91%
    Couleur et forme :Solid
    Masse moléculaire :723.84