Survivant
Les inhibiteurs de survivine ciblent la protéine survivine, un membre de la famille des inhibiteurs de l'apoptose (IAP) qui est fortement exprimée dans les cellules cancéreuses et les aide à échapper à l'apoptose. La survivine joue un rôle clé dans la régulation du cycle cellulaire et l'inhibition de l'apoptose, ce qui en fait une cible critique en thérapie anticancéreuse. En inhibant la survivine, ces composés peuvent promouvoir l'apoptose dans les cellules cancéreuses, offrant ainsi des bénéfices thérapeutiques potentiels. Chez CymitQuimica, nous offrons une sélection d'inhibiteurs de survivine de haute qualité pour soutenir vos recherches en oncologie, apoptose et développement thérapeutique.
14 produits trouvés pour "Survivant"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
MNK8
CAS :MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.Formule :C15H12N2O2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :252.27ZLDI-8
CAS :ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.
Formule :C24H23N3O3SDegré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :433.52MX106-4C
MX106-4C is a survivin inhibitor that selectively targets ABCB1-positive colorectal cancer cells. It can work synergistically with Doxorubicin for enhanced anticancer effects or restore Doxorubicin sensitivity in drug-resistant ABCB1 cells.Formule :C23H25BrN2O2Masse moléculaire :440.10994HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Couleur et forme :Lyophilized PowderMasse moléculaire :The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result.NSC 80467
CAS :NSC 80467 inhibits survivin, targets DNA synthesis, induces γH2AX, and pKAP1 markers of DNA damage.Formule :C24H22BrN3O5Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :512.35HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Couleur et forme :Lyophilized PowderMasse moléculaire :The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 55-63 kDa based on Tris-Bis PAGE result.HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Couleur et forme :Lyophilized PowderMasse moléculaire :The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.LQZ-7I
CAS :LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumorsFormule :C20H14F2N4Degré de pureté :99.81% - 99.87%Couleur et forme :SolidMasse moléculaire :348.35Cucurbitacin IIA
CAS :1.Formule :C32H50O8Degré de pureté :98.62% - 99.87%Couleur et forme :SolidMasse moléculaire :562.73Isolinderalactone
CAS :Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formule :C15H16O3Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :244.291-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS :SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.Formule :C21H13ClF3N3O2Degré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :431.8Ref: TM-T22424
1mg42,00€2mg55,00€5mg88,00€10mg127,00€25mg264,00€50mg432,00€100mg622,00€200mg873,00€1mL*10mM (DMSO)99,00€Sepantronium bromide
CAS :Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.
Formule :C20H19BrN4O3Degré de pureté :99.68% - 99.85%Couleur et forme :SolidMasse moléculaire :443.26GDP366
CAS :GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.Formule :C20H17N5OSDegré de pureté :98.78% - 99.84%Couleur et forme :SolidMasse moléculaire :375.45AQIM-I
CAS :AQIM-I is a survivin inhibitor that reduces survivin expression and colony formation. It promotes reactive oxygen species (ROS) production, apoptosis, cell cycle arrest, DNA damage, and autophagy. Moreover, AQIM-I effectively inhibits nonsmall cell lung cancer cells A549, with an IC 50 value of 9 nM [1].
Formule :C17H13IN2O2Couleur et forme :SolidMasse moléculaire :404.20
