Intégrine
Les inhibiteurs d'intégrines ciblent les intégrines, une famille de récepteurs de surface cellulaire qui jouent un rôle crucial dans l'adhésion cellulaire, la migration et la transduction du signal. Les intégrines sont impliquées dans la régulation du cycle cellulaire, en particulier dans des processus tels que la division et la différenciation cellulaires. Inhiber les intégrines peut perturber ces processus, entraînant un arrêt du cycle cellulaire et l'apoptose, ce qui rend ces inhibiteurs précieux dans la recherche sur le cancer et l'étude des métastases. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs d'intégrines de haute qualité pour soutenir vos recherches sur la régulation du cycle cellulaire, la biologie du cancer et le développement thérapeutique.
224 produits trouvés pour "Intégrine"
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Abituzumab
CAS :<p>Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.</p>Degré de pureté :>95%Couleur et forme :LiquidElarofiban TFA
CAS :<p>Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.</p>Formule :C26H34F6N4O8Degré de pureté :99.08%Couleur et forme :SoildMasse moléculaire :644.56Teplizumab
CAS :<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Degré de pureté :SDS-PAGE:95.8%;SEC-HPLC:99.7%Couleur et forme :LiquidMasse moléculaire :145.79 kDaAbciximab
CAS :<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Degré de pureté :SDS-PAGE:95.2%;SEC-HPLC:95.9%Couleur et forme :LiquidMasse moléculaire :95.18 kDaAbrilumab
CAS :<p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>Degré de pureté :98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Couleur et forme :LiquidRWJ 50271
CAS :<p>RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.</p>Formule :C18H17F3N4O2SDegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :410.41Efalizumab
CAS :<p>Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:98.77%Couleur et forme :LiquidMasse moléculaire :146.14 kDaVedolizumab
CAS :<p>Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.</p>Degré de pureté :SDS-PAGE:98.4%;SEC-HPLC:99.1%Couleur et forme :LiquidMasse moléculaire :146.80 kDaATN-161 trifluoroacetate salt
CAS :<p>ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.</p>Formule :C25H36F3N9O10SDegré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :711.67Tadocizumab
CAS :<p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>Degré de pureté :97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Couleur et forme :LiquidOrbofiban TFA
CAS :<p>Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary</p>Formule :C19H24F3N5O6Degré de pureté :97.21% - 98.72%Couleur et forme :SolidMasse moléculaire :475.42Foralumab
CAS :<p>Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.</p>Degré de pureté :96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Couleur et forme :LiquidOtelixizumab
CAS :<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Degré de pureté :>95%Couleur et forme :LiquidTidutamab
CAS :<p>Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).</p>Degré de pureté :97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Couleur et forme :LiquidCibisatamab
CAS :<p>Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.</p>Degré de pureté :SDS-PAGE:99.1%;SEC-HPLC:96.5%Couleur et forme :LiquidMasse moléculaire :191.1 kDaBersanlimab
CAS :<p>Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.</p>Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :144.22 kDaSMS 121
CAS :<p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>Formule :C20H21NO5Degré de pureté :98.29%Couleur et forme :SoildMasse moléculaire :355.38DSPE-PEG5000-cRGD
<p>DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.</p>Couleur et forme :Odour SolidLDV FITC
CAS :<p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>Formule :C69H81N11O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1368.53Bimosiamose
CAS :<p>Bimosiamose has anti-inflammatory effects[1].</p>Formule :C46H54O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :862.91Gantofiban
CAS :<p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>Formule :C21H29N5O6Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :447.48PLN-1474
CAS :<p>PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.</p>Formule :C24H37N3O4Degré de pureté :99.92%Couleur et forme :SoildMasse moléculaire :431.57DSPE-PEG3000-iRGD
<p>DSPE-PEG3000-iRGD is a PEG compound comprising DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrin and undergoes proteolytic cleavage within tumors to produce CRGDK/R, interacting with neuropilin-1. This results in tumor targeting and penetration capabilities. DSPE-PEG3000-iRGD is applicable in drug delivery.</p>Couleur et forme :Odour SolidTC113
<p>TC113, a c(RGDyK)-linked Gemcitabine, targets αvβ3 integrin, entering A549 cells, and inhibits WM266.4 and A549 cell growth.</p>Formule :C37H50F2N12O13Couleur et forme :SolidMasse moléculaire :908.86αVβ8-IN-1
CAS :<p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>Formule :C25H32ClN5O4Couleur et forme :SolidMasse moléculaire :502.012-Methylbutyrylcarnitine chloride
<p>2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.</p>Formule :C12H24ClNO4Couleur et forme :SolidMasse moléculaire :281.78Catumaxomab
CAS :<p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>Degré de pureté :95%Couleur et forme :LiquidGRGDSP
CAS :<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Formule :C22H37N9O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.58AB-3PRGD2
CAS :<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Formule :C137H215IN30O45SCouleur et forme :SolidMasse moléculaire :3161.32Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Formule :C25H41N11O8SCouleur et forme :SolidMasse moléculaire :655.727Mumefural
CAS :<p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>Formule :C12H12O9Couleur et forme :SolidMasse moléculaire :300.22Anti-EMMPRIN/CD147 Antibody
<p>Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Couleur et forme :Odour LiquidDSPE-PEG2000-iRGD
<p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>Couleur et forme :Odour SolidDSPE-PEG2000-cRGD
<p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>Couleur et forme :Odour SolidDSPE-PEG1000-cRGD
<p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>Couleur et forme :Odour SolidFibronectin CS1 Peptide
CAS :<p>Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.</p>Formule :C38H64N8O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :872.96huATN-658
<p>huATN-658 (MNPR-101) is a humanized monoclonal antibody inhibitor targeting the urokinase-type plasminogen activator receptor (uPAR). It effectively disrupts the interaction between uPAR and integrins, thereby inhibiting tumor cell proliferation, invasion, and migration. huATN-658 shows potential for research in breast cancer, particularly in cases of triple-negative breast cancer.</p>Couleur et forme :Odour Liquidc(phg-isoDGR-(NMe)k) TFA
<p>C(phg-isoDGR-(NMe)k) TFA is a selective and potent ligand for α5β1-integrin, exhibiting an IC50 of 2.9 nM [1].</p>Formule :C29H42F3N9O9Couleur et forme :SolidMasse moléculaire :717.69LXY3
CAS :<p>LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.</p>Formule :C32H43N11O15S2Couleur et forme :SolidMasse moléculaire :885.88STX-100
<p>PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.</p>Degré de pureté :97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :Odour LiquidEtrolizumab
CAS :<p>MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.</p>Degré de pureté :98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)Couleur et forme :LiquidObtustatin
<p>Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.</p>Formule :C184H284N52O57S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4393.07Fuzapladib
CAS :<p>Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.</p>Formule :C15H20F3N3O3SDegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :379.4Echistatin
CAS :<p>Potent αVβ3 integrin blocker, stops osteoclast binding & bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).</p>Formule :C217H341N71O74S9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5417.1PDI-IN-4
<p>PDI-IN-4 (Compound 14d) is a protein disulfide isomerase inhibitor with an IC50 value of 0.48 μM. It prevents platelet aggregation and thrombosis by reducing the activation of GPIIb/IIIa, without causing significant cytotoxicity. PDI-IN-4 is applicable in thrombosis research.</p>Formule :C17H12F3NO2Couleur et forme :SolidMasse moléculaire :319.278DSPE-PEG1000-iRGD
<p>DSPE-PEG1000-iRGD is a PEG compound made from DSPE and the αv-integrin-targeting peptide (iRGD). The iRGD peptide initially binds to αv-integrins and undergoes proteolytic cleavage within tumors to produce CRGDK/R, which interacts with neuropilin-1, thereby facilitating tumor targeting and penetration. DSPE-PEG1000-iRGD is useful for drug delivery applications.</p>Couleur et forme :Odour SolidHSDVHK-NH2
CAS :<p>Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.</p>Formule :C30H48N12O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :720.78Gly-Arg-Gly-Asp-Ser
CAS :<p>Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.</p>Formule :C17H30N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.47α2β1 Integrin Ligand Peptide
CAS :<p>The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular</p>Formule :C14H22N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.35K34c hydrochloride
CAS :<p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>Formule :C26H30ClN3O4Degré de pureté :99.76% - 99.89%Couleur et forme :SoildMasse moléculaire :483.99Fradafiban hydrochloride
<p>Fradafiban (BIBU-52) is a nonpeptide GPIIb/IIIa antagonist with Kd 148 nM for human platelets.</p>Formule :C20H22ClN3O4Couleur et forme :SolidMasse moléculaire :403.86Dafsolimab
CAS :<p>Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is</p>Couleur et forme :LiquidBesufetamig
CAS :<p>Besufetamig is a bispecific antibody targeting programmed cell death protein 1 (PD-1) and the CD3ε chain. It modulates immune cell activity, exerting both immunosuppressive and antitumor effects. Besufetamig holds promise for cancer research.</p>Couleur et forme :Liquidαvβ5 integrin-IN-1
CAS :<p>αvβ5 integrin-IN-1, a potent and selective αvβ5 integrin inhibitor, exhibits a high inhibitory potency with a pIC50 value of 8.2.</p>Formule :C25H28F3N3O3Couleur et forme :SolidMasse moléculaire :475.512LDV
CAS :<p>α4β1 integrin (VLA-4) ligand (Kd ~ 12 nM). Non-fluorescent derivative of LDV FITC.</p>Formule :C48H70N10O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :979.13Odulimomab
CAS :<p>Odulimomab: anti-LFA-1 antibody, inhibits T cell growth, protects against ischemic injury, used in transplant rejection research.</p>Couleur et forme :Liquidα2β1 Integrin Ligand Peptide TFA
<p>α2β1 Integrin Ligand Peptide TFA interacts with the integrin receptor on the cell membrane and enters the cell to mediate extracellular signaling.It is a</p>Formule :C16H23F3N4O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.37Echistatin TFA
<p>Echistatin TFA: a minimal RGD protein from snake venom; inhibits platelet aggregation and bone resorption; targets αIIbβ3, αvβ3, α5β1.</p>Couleur et forme :Odour SolidOrbofiban acetate
CAS :<p>Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered</p>Formule :C19H27N5O6Couleur et forme :SolidMasse moléculaire :421.45R-BC154 acetate
<p>R-BC154 acetate: selective α9β1 antagonist, high-affinity integrin probe for α9β1/α4β1 activity study.</p>Formule :C56H65N9O14S3Couleur et forme :SolidMasse moléculaire :1184.36EMD527040
CAS :<p>EMD527040 is a potent αvβ6 antagonist with antifibrotic effects, used in carcinoma and liver fibrosis research.</p>Formule :C29H32Cl2N4O5Couleur et forme :SolidMasse moléculaire :587.5BIO5192 hydrate
<p>BIO5192 hydrate: potent α4β1 inhibitor, binds selectively (Kd<10 pM, IC50=1.8 nM), boosts murine HSPC mobilization 30x.</p>Couleur et forme :SolidGanodermaones B
<p>Ganodermaones B is a renal fibrosis inhibitor. Ganodermaones B inhibits TGF-β1-induced collagen I and fibronectin expression .</p>Formule :C21H26O5Couleur et forme :SolidMasse moléculaire :358.43KGDS
CAS :<p>KGDS is a synthetic peptide that targets the integrin GPIIb-IIIa on the membrane of activated human platelets, with the amino acid sequence Lys-Gly-Asp-Ser [1].</p>Formule :C15H27N5O8Couleur et forme :SolidMasse moléculaire :405.4Lys-Gln-Ala-Gly-Asp-Val
CAS :<p>KQAGDV is a fibrinogen γ-chain cell adhesion peptide, targeting α2bβ3 integrin, and binds SMCs.</p>Formule :C25H44N8O10Couleur et forme :SolidMasse moléculaire :616.66GRGDSPK TFA
<p>GRGDSPK TFA is an RGD peptide, competitive inhibitor of integrin-fibronectin, used to research integrins in bone dynamics.</p>Formule :C30H50F3N11O13Couleur et forme :SolidMasse moléculaire :829.78Integrin Binding Peptide
CAS :<p>Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.</p>Formule :C42H63N15O16SCouleur et forme :SolidMasse moléculaire :1066.12MS133
<p>MS133 is a human bispecific antibody targeting CD133/PROM1 and CD3E. It is used in the study of colon cancer.</p>Couleur et forme :Odour LiquidRTDLDSLRTYTL
CAS :<p>RTDLDSLRTYTL is a high-affinity and specific inhibitor of Alpha (v) beta (6) integrin (avb6). By binding to the avb6 integrin, this peptide sequence activates T cell cytotoxicity and cytokine production, such as interferon-γ. Through the design of chimeric T cell antigen receptors (CAR), RTDLDSLRTYTL enables T cells to be redirected, allowing them to specifically recognize and attack tumor cells. It is used in research for cancer immunotherapy and the development of targeted drugs.</p>Formule :C62H104N18O22Couleur et forme :SolidMasse moléculaire :1453.60HSDVHK-NH2 TFA
<p>HSDVHK-NH2 TFA acts as an antagonist to the αvβ3-vitronectin integrin interaction, displaying an inhibitory concentration (IC 50) of 1.74 pg/mL (2.414 pM) [1] [</p>Formule :C32H49F3N12O11Couleur et forme :SolidMasse moléculaire :834.8Forimtamig
<p>Forimtamig (RG-6324) is a bispecific antibody that targets GPRC5D and CD3 T cells. It features a 2 + 1 structure, comprising two high-affinity GPRC5D binding segments and one CD3-binding module. Forimtamig is engineered with a P329G LALA mutation in its Fc domain to prevent Fcγ receptor and C1q binding, while maintaining Fc receptor interaction. Its isotype control corresponds to human IgG1 kappa.</p>Couleur et forme :Odour LiquidA20FMDV2
CAS :<p>A20FMDV2 is a highly selective αvβ6 integrin inhibitor with an IC 50 of 3 nM, demonstrating 1,000-fold greater selectivity for αvβ6 compared to other RGD-directed integrins like αvβ3, αvβ5, and α5β1. This compound can be derived from the foot-and-mouth disease virus and is suitable for radiolabeling, enabling PET imaging of αvβ6 integrin-positive tumors.</p>Formule :C93H163N31O28Couleur et forme :SolidMasse moléculaire :2163.48Anti-GPRC5D Antibody
<p>Anti-GPRC5D Antibody is a humanized IgG1 monoclonal antibody targeting GPRC5D. It serves as the antibody component of the ADC molecule LM-305.</p>Couleur et forme :Odour LiquidBimosiamose disodium
CAS :<p>Bimosiamose disodium (TBC-1269Z), a pan-selectin inhibitor, has IC50s: E-selectin 88 μM, P-selectin 20 μM, L-selectin 86 μM; anti-inflammatory.</p>Formule :C46H52Na2O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :906.88P8RI acetate
<p>P8RI acetate mimics CD31, activates CDP8RI, and suppresses the immune response by restoring CD31 pathway.</p>Formule :C53H81N13O11Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :1076.29Dentonin TFA
<p>Dentonin TFA (AC-100 TFA) is a short peptide fragment derived from MEPE. It enhances osteogenesis by promoting the adhesion of osteoprogenitor cells and supports the survival of immature adherent cells. Dentonin TFA does not have a significant effect on mature osteoblasts and can be utilized in studies of phosphate homeostasis and bone metabolism.</p>Formule :C109H161F3N30O44Masse moléculaire :2651.1235LDV-FITC TFA
<p>LDV-FITC TFA is a fluorescent peptide, specifically an FITC-conjugated LDV peptide. This compound binds to the α4β1 integrin with high affinity, displaying a Kd of 0.3 nM in the presence of Mn2+ and 12 nM in its absence, when binding to U937 cells. LDV-FITC TFA is useful for assessing α4β1 integrin affinity.</p>Formule :C69H81N11O17S·xC2HF3O2Lamifiban trifluoroacetate
CAS :<p>Lamifiban trifluoroacetate is an antagonist of the nonpeptide platelet fibrinogen receptor (GPIIb/IIIa).</p>Formule :C26H29F3N4O8Couleur et forme :SolidMasse moléculaire :582.533ICAM-1988
CAS :<p>ICAM-1988 is a LFA-1 antagonist.</p>Formule :C22H22Cl2N4O6SCouleur et forme :SolidMasse moléculaire :541.4Variabilin
CAS :<p>Variabilin is a natural product that can be used as a reference standard. The CAS number of Variabilin is 3187-52-8.</p>Formule :C17H16O5Couleur et forme :SolidMasse moléculaire :300.31Arg-Gly-Glu-Ser
CAS :<p>Arg-Gly-Glu-Ser is a RGD related peptide that is a control for the RGDS activity of fibrinogen binding to activated platelets.</p>Formule :C16H29N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.44Risuteganib
CAS :<p>Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide that regulates the functions of multiple integrin isoforms.</p>Formule :C22H39N9O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :637.66αvβ6-IN-1
<p>αvβ6-IN-1 (compound 28) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 8.1. This compound shows potential for research in idiopathic pulmonary fibrosis.</p>Formule :C25H32F2N4O3Couleur et forme :SolidMasse moléculaire :474.54αvβ6-IN-2
<p>αvβ6-IN-2 (compound 20) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 7.8. It shows potential for use in research on idiopathic pulmonary fibrosis.</p>Formule :C25H30F3N3O3Couleur et forme :SolidMasse moléculaire :477.52c(avb6)-DOTA TFA
<p>c(avb6)-DOTA TFA is a conjugate formed by the coupling of a selective αvβ6 integrin cyclic peptide and a DPTA chelating agent. The Lu (III) complex of c(avb6)-DOTA TFA exhibits considerable affinity for αvβ6 integrin (IC50=0.8 nM), making it suitable for tumor diagnostics.</p>Formule :C69H102F3N17O20Couleur et forme :SolidMasse moléculaire :1546.65Indatuximab
<p>Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.</p>Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :145.5 kDaGRGDSPK
CAS :<p>GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.</p>Formule :C28H49N11O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :715.76C16Y
CAS :<p>C16Y, a short peptide, serves as an inhibitor for the integrins αvβ3 and α5β1. It targets the cell membrane and exerts its antitumor activity by inhibiting angiogenesis.</p>Formule :C78H115N17O17Couleur et forme :SolidMasse moléculaire :1562.85GSK 3008348 hydrochloride
CAS :<p>GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.</p>Formule :C29H37N5O2xHClDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :0Azelaoyl PAF
CAS :<p>Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones.promotes the uptake of oxLDL by macrophages by upregulating CD36 expression.</p>Formule :C33H66NO9PCouleur et forme :SolidMasse moléculaire :651.85Obtustatin triacetate
<p>Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of the</p>Formule :C184H284N52O57S8·3C2H4O2Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :4573.21BT100
<p>BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, thus obstructing arterial thrombosis [1].</p>Degré de pureté :98%Couleur et forme :Odour SolidVolociximab
CAS :<p>Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor and anticancer activity, inhibits the growth of rabbit VX2 tumors and is used to study solid tumors.</p>Degré de pureté :95%Couleur et forme :LiquidMK-0429
CAS :<p>MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM).</p>Formule :C23H29N5O4Couleur et forme :SolidMasse moléculaire :439.51Cilengitide TFA
CAS :<p>Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.</p>Formule :C29H41F3N8O9Couleur et forme :SolidMasse moléculaire :702.68Anti-Mouse CD3 Antibody (17A2)
<p>Anti-Mouse CD3 Antibody (17A2) is an IgG2b class antibody of murine origin targeting CD3 and can be used to study TCR signaling and antigen recognition.</p>Couleur et forme :Odour LiquidLifitegrast sodium
CAS :<p>Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.</p>Formule :C29H23Cl2N2NaO7SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :637.46GPRP
CAS :<p>GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.</p>Formule :C18H31N7O5Couleur et forme :White To Off-White PowderMasse moléculaire :425.48RGD Trifluoroacetate
CAS :<p>RGD Trifluoroacetate is a tripeptide for cell adhesion, effective on 24 integrins, and widely used for synthetic surface binding.</p>Formule :C14H23F3N6O8Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :460.36Cilengitide
CAS :<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Formule :C27H40N8O7Degré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :588.66A-205804
CAS :<p>A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.</p>Formule :C15H12N2OS2Degré de pureté :98.07% - 98.52%Couleur et forme :SolidMasse moléculaire :300.4Cyclo(-RGDfK)
CAS :<p>Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.</p>Formule :C27H41N9O7Degré de pureté :95.29% - >99.99%Couleur et forme :SolidMasse moléculaire :603.67PND-1186
CAS :<p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>Formule :C25H26F3N5O3Degré de pureté :99.14% - 99.75%Couleur et forme :SolidMasse moléculaire :501.5GLPG0187
CAS :<p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>Formule :C29H37N7O5SDegré de pureté :99.4% - 99.70%Couleur et forme :SolidMasse moléculaire :595.71OSU-T315
CAS :<p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>Formule :C30H30F3N5ODegré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :533.59Arginine-glycine-aspartic acid
CAS :<p>RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.</p>Formule :C12H22N6O6Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :346.34Cyclo(RADfK)
CAS :<p>Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.</p>Formule :C28H43N9O7Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :617.7Cyclo(-RGDfK) TFA
CAS :<p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>Formule :C29H42F3N9O9Degré de pureté :98.99% - 99.54%Couleur et forme :SolidMasse moléculaire :717.69CWHM-12
CAS :<p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>Formule :C26H32BrN5O6Degré de pureté :98.05% - 99.83%Couleur et forme :SolidMasse moléculaire :590.47H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS :<p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>Formule :C23H38N10O10Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :614.61iRGD peptide
CAS :<p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>Formule :C35H57N13O14S2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :948.04Leukadherin-1
CAS :<p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>Formule :C22H15NO4S2Degré de pureté :98.49% - 98.93%Couleur et forme :SolidMasse moléculaire :421.49Pyrintegrin
CAS :<p>Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.</p>Formule :C23H25N5O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :451.54Orbofiban
CAS :<p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>Formule :C17H23N5O4Couleur et forme :SolidMasse moléculaire :361.4Cucurbitacin B
CAS :<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Formule :C32H46O8Degré de pureté :97.1% - 99.33%Couleur et forme :SolidMasse moléculaire :558.7ILK-IN-2
CAS :<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Formule :C30H30F3N5ODegré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :533.59A-286982
CAS :<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Formule :C24H27N3O4SDegré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :453.55Arg-Gly-Asp TFA (99896-85-2(free base))
<p>Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.</p>Formule :C14H23F3N6O8Degré de pureté :99.2% - ≥98%Couleur et forme :SolidMasse moléculaire :460.36roxifiban
CAS :<p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>Formule :C21H29N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.48LXW7
CAS :<p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>Formule :C29H48N12O12S2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :820.89Natalizumab
CAS :<p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>Degré de pureté :98.00%Couleur et forme :LiquidMasse moléculaire :N/ALifitegrast
CAS :<p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>Formule :C29H24Cl2N2O7SDegré de pureté :99.39% - 99.66%Couleur et forme :SolidMasse moléculaire :615.48Irigenin
CAS :<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Formule :C18H16O8Degré de pureté :99.50% - 99.85%Couleur et forme :SolidMasse moléculaire :360.31Carotegrast methyl
CAS :<p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>Formule :C28H26Cl2N4O5Degré de pureté :99.26% - 99.72%Couleur et forme :SolidMasse moléculaire :569.44Tirofiban hydrochloride monohydrate
CAS :<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Formule :C22H39ClN2O6SDegré de pureté :98.81% - >99.99%Couleur et forme :White SolidMasse moléculaire :495.07E7820
CAS :<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Formule :C17H12N4O2SDegré de pureté :98.31% - 99.11%Couleur et forme :SolidMasse moléculaire :336.37ILK-IN-3
CAS :<p>ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.</p>Formule :C10H12N6ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :232.24Cyclo(RGDyK) trifluoroacetate
CAS :<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Formule :C31H43F6N9O12Degré de pureté :95.28% - ≥95%Couleur et forme :SolidMasse moléculaire :847.72TR-14035
CAS :<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Formule :C24H21Cl2NO5Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :474.33BIO-1211
CAS :<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Formule :C36H48N6O9Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :708.8Eptifibatide acetate (148031-34-9 free base)
CAS :<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Formule :C35H49N11O9S2·xC2H4O2Degré de pureté :99.7% - 99.87%Couleur et forme :SolidMasse moléculaire :831.96 (free base)GPRP acetate (67869-62-9 free base)
CAS :<p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>Formule :C20H35N7O7Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :485.53Bexotegrast
CAS :<p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>Formule :C27H36N6O3Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :492.61Etaracizumab
CAS :<p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>Degré de pureté :96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.3 (kDa)Muromonab
CAS :<p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>Degré de pureté :95% - 97.51% (SEC-HPLC)Couleur et forme :LiquidRO0270608
CAS :<p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>Formule :C24H19Cl3N2O4Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :505.78Voxalatamab
CAS :<p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>Couleur et forme :LiquidRovelizumab
CAS :<p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>Couleur et forme :LiquidVepsitamab
CAS :<p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>Couleur et forme :LiquidCevostamab
CAS :<p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>Couleur et forme :LiquidPavurutamab
CAS :<p>Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.</p>Couleur et forme :LiquidEnlimomab
CAS :<p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>Couleur et forme :LiquidAnti-Mouse IL-1a Antibody (ALF-161)
<p>Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.</p>Degré de pureté :98%Couleur et forme :Odour LiquidPasotuxizumab
CAS :<p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.</p>Couleur et forme :LiquidUbamatamab
CAS :<p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>Couleur et forme :LiquidVatelizumab
CAS :<p>Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.</p>Degré de pureté :95%Couleur et forme :LiquidTepoditamab
CAS :<p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>Couleur et forme :LiquidVonsetamig
CAS :<p>Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.</p>Couleur et forme :LiquidFlotetuzumab
CAS :<p>Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.</p>Couleur et forme :LiquidLinvoseltamab
CAS :<p>Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/</p>Couleur et forme :LiquidVibecotamab
CAS :<p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>Couleur et forme :LiquidObrindatamab
CAS :<p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>Couleur et forme :LiquidPacanalotamab
CAS :<p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>Couleur et forme :LiquidOS-2966
<p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>Degré de pureté :95%Couleur et forme :Odour LiquidAnti-Mouse CD3ε Antibody (145-2C11)
<p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>Degré de pureté :99%Couleur et forme :Odour LiquidGresonitamab
CAS :<p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>Couleur et forme :LiquidSB273005
CAS :<p>SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.</p>Formule :C22H24F3N3O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :451.44Tirofiban
CAS :<p>Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.</p>Formule :C22H36N2O5SDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :440.6GR 144053 trihydrochloride
CAS :<p>platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist</p>Formule :C18H30Cl3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.82Sibrafiban
CAS :<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Formule :C20H28N4O6Couleur et forme :SolidMasse moléculaire :420.46UR-3216
CAS :<p>UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.</p>Formule :C27H29N7O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :563.56L 703014
CAS :<p>L 703014 is an antagonist of the fibrinogen receptor.</p>Formule :C24H34N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :442.55Balamapimod
CAS :<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Formule :C30H32ClN7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :574.14BMS-587101
CAS :<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Formule :C26H20Cl2N4O4SCouleur et forme :SolidMasse moléculaire :555.43BMS-688521
CAS :<p>BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.</p>Formule :C26H19Cl2N5O4Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :536.37MK-0668
CAS :<p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>Formule :C31H30Cl2N6O6SCouleur et forme :SolidMasse moléculaire :685.58NSC47924
CAS :<p>NSC47924 is a laminin receptor (LR) inhibitor.</p>Formule :C18H17NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.33Zalunfiban
CAS :<p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>Formule :C16H18N8O2SCouleur et forme :SolidMasse moléculaire :386.43TCS 2314
CAS :<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Formule :C28H34N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :522.59Chrysotobibenzyl
CAS :<p>Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.</p>Formule :C19H24O5Couleur et forme :SolidMasse moléculaire :332.39αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Formule :C28H35F3N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :672.67Zaurategrast ethyl ester sulfate
CAS :<p>Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.</p>Formule :C56H60Br2N8O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1197.01RUC-1
CAS :<p>RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.</p>Formule :C11H15N5OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :265.33Zaurategrast ethyl ester
CAS :<p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>Formule :C28H29BrN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :549.46IMB-10
CAS :<p>IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.</p>Formule :C19H15NOS2Couleur et forme :SolidMasse moléculaire :337.46Ro 43-5054
CAS :<p>Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.</p>Formule :C24H27N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.5BOP sodium
CAS :<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Formule :C25H29N3NaO7SCouleur et forme :SolidMasse moléculaire :538.57GSK-3008348
CAS :<p>GSK-3008348 is an antagonist of integrin alpha(v)beta6.</p>Formule :C29H37N5O2Degré de pureté :99.547%Couleur et forme :SolidMasse moléculaire :487.64Valategrast
CAS :<p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>Formule :C30H32Cl3N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :604.95Valategrast hydrochloride
CAS :<p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>Formule :C30H33Cl4N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.41CLT-28643
CAS :<p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>Formule :C19H17N3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :351.36Integrin-IN-2
CAS :<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Formule :C27H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.55XVA143
CAS :<p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>Formule :C25H21Cl2N3O8Couleur et forme :SolidMasse moléculaire :562.36Integrin modulator 1
CAS :<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Formule :C13H14N2O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :262.26Firategrast
CAS :<p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>Formule :C27H27F2NO6Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :499.5Elarofiban
CAS :<p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>Formule :C22H32N4O4Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :416.513-Hydroxyxanthone
CAS :<p>3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein</p>Formule :C13H8O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :212.2ICAM-1-IN-1
CAS :<p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>Formule :C15H11BrN2O2SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :363.23BI-1950
CAS :<p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>Formule :C32H26Cl2FN7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :646.5Teclistamab
CAS :<p>Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.</p>Degré de pureté :95%Couleur et forme :LiquidSynstatin (92-119)
CAS :<p>Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and</p>Formule :C133H207N35O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3032.27TAK 029
CAS :<p>TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.</p>Formule :C19H23N5O7Couleur et forme :SolidMasse moléculaire :433.42αvβ6 integrin inhibitor 2
CAS :<p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>Formule :C21H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.49Lotrafiban
CAS :<p>Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.</p>Formule :C23H32N4O4Couleur et forme :SolidMasse moléculaire :428.52JNJ-26076713
CAS :<p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>Formule :C29H38N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.64SB-267268
CAS :<p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>Formule :C22H24F3N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.44Zaurategrast
CAS :<p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>Formule :C26H25BrN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.41Solitomab
CAS :<p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>Couleur et forme :LiquidCarotegrast
CAS :<p>Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.</p>Formule :C27H24Cl2N4O5Couleur et forme :SolidMasse moléculaire :555.41Tirofiban HCl
CAS :<p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>Formule :C22H37ClN2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.06
