Microtubules associés
Les inhibiteurs des protéines associées aux microtubules ciblent les protéines qui interagissent avec les microtubules, les composants structurels du cytosquelette de la cellule qui sont essentiels à la division cellulaire. Ces protéines régulent la stabilité et la dynamique des microtubules pendant la mitose. L'inhibition des protéines associées aux microtubules peut perturber la fonction des microtubules, entraînant un arrêt du cycle cellulaire et l'apoptose, en particulier dans les cellules cancéreuses à division rapide. Ces inhibiteurs sont largement utilisés dans la recherche sur le cancer et le développement de médicaments. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de protéines associées aux microtubules de haute qualité pour soutenir vos recherches sur la division cellulaire, la dynamique du cytosquelette et la thérapie contre le cancer.
262 produits trouvés pour "Microtubules associés"
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AC 7739
CAS :<p>AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.</p>Formule :C18H22ClNO4Degré de pureté :99.38% - 99.55%Couleur et forme :SoildMasse moléculaire :351.83Bepranemab
CAS :<p>Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.</p>Degré de pureté :99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Couleur et forme :LiquidTilavonemab
CAS :<p>Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.</p>Degré de pureté :95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Couleur et forme :LiquidEntasobulin
CAS :<p>Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.</p>Formule :C26H18ClN3O2Degré de pureté :98.40%Couleur et forme :SolidMasse moléculaire :439.89Verubulin hydrochloride
CAS :<p>Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic</p>Formule :C17H18ClN3ODegré de pureté :98.29% - 99.77%Couleur et forme :SolidMasse moléculaire :315.8DM4
CAS :<p>DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.</p>Formule :C38H54ClN3O10SDegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :780.37Zagotenemab
CAS :<p>Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.</p>Degré de pureté :95% - > 95%Couleur et forme :LiquidMasse moléculaire :145.3 kDaTirbanibulin Mesylate
CAS :<p>Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Formule :C27H33N3O6SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :527.63Tubulin inhibitor 6
CAS :<p>Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.</p>Formule :C20H14ClNO2SDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :367.85BNC105
CAS :<p>BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.</p>Formule :C20H20O7Degré de pureté :96.57%Couleur et forme :SolidMasse moléculaire :372.37Anticancer agent 139
<p>Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating high</p>Formule :C16H12F3N3OCouleur et forme :SolidMasse moléculaire :319.28Tubulin inhibitor 24
CAS :<p>Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.</p>Formule :C22H21N3O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :375.42Cys-McMMAF
CAS :<p>Cys-McMMAF, a microtubule-disrupting agent linked to an anti-5T4 antibody, shows antitumor effects in mouse models.</p>Formule :C52H83N7O13SCouleur et forme :SolidMasse moléculaire :1046.32cis-trismethoxy Resveratrol
CAS :<p>cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.</p>Formule :C17H18O3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :270.32Larotaxel dihydrate
CAS :<p>Larotaxel dihydrate possesses antineoplastic activity.</p>Formule :C45H57NO16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :867.93KIF18A-IN-2
CAS :<p>KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.</p>Formule :C25H34N4O5S2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :534.69Phomopsin A
CAS :<p>Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.</p>Formule :C36H45ClN6O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :789.23Vinzolidine
CAS :<p>Vinzolidine is a semi-synthetic vinca alkaloid. It exerts cytotoxic effects on tumor cells by inhibiting cell division through disruption of tubulin polymerization. Vinzolidine can be utilized in research to investigate synergy with other chemotherapy or biotherapy drugs, as well as cancer cell tolerance or resistance, and to explore strategies to overcome these challenges.</p>Formule :C48H58ClN5O9Couleur et forme :SolidMasse moléculaire :884.46T-900607
CAS :<p>T-900607 is a novel microtubule protein active agent that disrupts microtubule polymerization through a unique mechanism of action. t-900607 is cardiotoxic.</p>Formule :C14H10F5N3O4SDegré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :411.3PROTAC tubulin-Degrader-1
<p>PROTAC tubulin-Degrader-1 (Compound W13) functions as an inhibitor of PROTAC tubulin and exhibits anti-tumor activity against human lung cancer.</p>Couleur et forme :Odour SolidTubulin polymerization-IN-55
CAS :<p>Tubulin polymerisation-IN-55 is a Tubulin Polymerization inhibitor that displays antiproliferative effects on A549, K562, HepG2, MDA-MB-231 and HFL-1.</p>Formule :C22H24N2O4Degré de pureté :98.68%Couleur et forme :SoildMasse moléculaire :380.44Microtubule destabilizing agent-1
CAS :<p>Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.</p>Formule :C22H26N4O4Couleur et forme :SolidMasse moléculaire :410.47Alestramustine
CAS :<p>Alestramustine: a cancer drug that targets microtubules in estrogen receptor-positive cells, impeding cell division.</p>Formule :C26H36Cl2N2O4Couleur et forme :SolidMasse moléculaire :511.48TNIR7-1A
CAS :<p>TNIR7-1A is a fused cycloheptatriene-BODIPY derivative that is optimized for near-infrared (NIR) imaging characteristics (Ex/Em = 600/774 nm in PBS) and exhibits high affinity and specificity for neurofibrillary tangles (NFT) in vitro. Additionally, TNIR7-1A can effectively penetrate the blood-brain barrier.</p>Formule :C23H20BF2N3Couleur et forme :SolidMasse moléculaire :387.23TTBK1-IN-2
CAS :<p>TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.</p>Formule :C18H13ClN4ODegré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :336.77Anhydrovinblastine sulfate
<p>Anhydrovinblastine sulfate is a monoterpene indole alkaloid that can be extracted from the leaves of Catharanthus roseus.</p>Formule :C46H60N4O16S2Masse moléculaire :988.34457SPA107
CAS :<p>SPA107 (Hemiasterlin methyl ester) is an analogue of Hemiasterlin. It inhibits tubulin polymerization, exhibiting antimitotic activity with an IC50 of 0.5 nM. SPA107 also shows cytotoxicity against p53 mutated MCF-7 cells, with an IC50 of 0.5 nM.</p>Formule :C31H48N4O4Couleur et forme :SolidMasse moléculaire :540.74Bifidenone
CAS :<p>Bifidenone is an effective tubulin polymerization inhibitor.</p>Formule :C21H26O5Couleur et forme :SolidMasse moléculaire :358.43Tubulin inhibitor 45
<p>Tubulin inhibitor 45 (compound 5) functions as an inhibitor of the active site of tubulin. It exhibits IC50 values of 11 μM for MCF7 cancer cells and 13 μM for HePG2 cancer cells.</p>Formule :C19H18N2O2SMasse moléculaire :338.1089Tubulin polymerization-IN-47
CAS :<p>Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer</p>Formule :C22H21N3O3Degré de pureté :99.64%Couleur et forme :SoildMasse moléculaire :375.427-Epi-10-oxo-docetaxel
CAS :<p>7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.</p>Formule :C43H51NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.86KIF18A-IN-12
CAS :<p>KIF18A-IN-12 (compound 9), a potent KIF18A inhibitor, exhibits an IC 50 of 45.54 nM and is utilized in cancer research.</p>Formule :C30H39F2N5O4SCouleur et forme :SolidMasse moléculaire :603.72Tubulin polymerization-IN-53
<p>Tubulin polymerization-IN-53 (compound 4b) serves as an inhibitor of β-tubulin polymerization and is capable of arresting the cell cycle at the G2/M stage.</p>Couleur et forme :Odour SolidCombretastatin A-1 phosphate tetrasodium
CAS :<p>OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.</p>Formule :C18H18Na4O12P2Couleur et forme :SolidMasse moléculaire :580.24Vinblastine
CAS :<p>Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.</p>Formule :C46H58N4O9Degré de pureté :97.42%Couleur et forme :PowderMasse moléculaire :810.97Ceratamine A
CAS :<p>Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.</p>Formule :C17H16Br2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.14Tubulin polymerization-IN-49
<p>Tubulin polymerization-IN-49 (compound 12d), a potent inhibitor of tubulin polymerization, binds to the colchicine site on tubulin, subsequently inducing cell</p>Formule :C20H24O5Couleur et forme :SolidMasse moléculaire :344.4Anti-α-Tubulin Antibody, AF555 conjugate
<p>Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for the</p>Couleur et forme :SolidTubulin inhibitor 38
<p>Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell</p>Formule :C17H13ClN6OSCouleur et forme :SolidMasse moléculaire :384.84Microtubule stabilizing agent-1
<p>Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [</p>Formule :C45H55NO13Couleur et forme :SolidMasse moléculaire :817.92Diminutol
CAS :<p>Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.</p>Formule :C19H26N6OSCouleur et forme :SolidMasse moléculaire :386.51Antiproliferative agent-66
Antiproliferative agent-66 (Compound B3) is an antiproliferative compound that induces apoptosis and causes cell cycle arrest. It demonstrates IC50 values ranging from 2.03 to 3.6 µM against SH-SY5Y neuroblastoma, HT-29 colorectal adenocarcinoma, and fibroblasts. Additionally, Antiproliferative agent-66 functions as a microtubule polymerization inhibitor with an IC50 of 0.79 µM.Formule :C18H15N3SCouleur et forme :SolidMasse moléculaire :305.397AADvac 1 TFA
AADvac 1 TFA is an active tau peptide vaccine utilized in Alzheimer's disease research. It is formed by conjugating the regulatory peptide 294KDNIKHVPGGGS305, which drives tau oligomerization, with keyhole limpet hemocyanin (KLH), and is formulated with aluminum hydroxide.TBL-100
<p>TBL-100 is a human monoclonal antibody (mAb) that targets Tau. It is applicable for research in Alzheimer's disease (AD) and progressive supranuclear palsy.</p>Couleur et forme :Odour LiquidSudocetaxel
CAS :<p>Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel.</p>Formule :C48H59NO16Couleur et forme :SolidMasse moléculaire :905.98Tubulin/PARP-IN-1
<p>Tubulin/PARP-IN-1 (compound 14) is a dual PARP-tubulin inhibitor with anti-endometrial cancer activity. It exhibits inhibitory concentration (IC50) values of 74 nM for PARP1, 109 nM for PARP2, and 1.4 μM for microtubules/tubulin. Tubulin/PARP-IN-1 induces apoptosis and autophagy, causing cell cycle arrest at the G2/M phase.</p>Formule :C19H13FO3Masse moléculaire :308.08487Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Formule :C83H127N25O34SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2051.11Pironetin
CAS :<p>Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.</p>Formule :C19H32O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.45Tubulin polymerization-IN-69
<p>Tubulin polymerization-IN-69 (compound 6c) exhibits significant inhibition of microtubule assembly in vitro, with an inhibition rate of 78.3% and an IC50 value of 6.53 μM. It rapidly induces apoptosis and G2/M phase cell cycle arrest in MCF-7 cells.</p>Couleur et forme :Odour SolidDihydrocephalomannine
CAS :<p>Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.</p>Formule :C45H55NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :833.928ALB-109564 dihydrochloride
CAS :<p>ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.</p>Formule :C47H62Cl2N4O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :929.99Tubulin inhibitor 48
CAS :<p>Tubulin inhibitor 48 (compound 16) is an anticancer agent targeting microtubules. It exhibits IC50 values of 0.1 μM and 0.07 μM against LN-229 and Capan-1 cells, respectively.</p>Formule :C21H22N4OCouleur et forme :SolidMasse moléculaire :346.43Tubulin polymerization-IN-44
<p>Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it</p>Formule :C19H15Cl2N3O3SCouleur et forme :SolidMasse moléculaire :436.31MT189
CAS :<p>MT189 (Antiproliferative agent-14) inhibits tubulin polymerization (IC50 3.41 μM), arrests G2/M cell cycle, and is highly antiproliferative.</p>Formule :C21H18FN3O2Degré de pureté :98.52%Couleur et forme :SoildMasse moléculaire :363.38Trimethylcolchicinic acid
CAS :<p>Trimethylcolchicinic acid is an orally available colchicine analog that binds to tubulin and inhibits its polymerization into microtubules,potential antitumor.</p>Formule :C19H21NO5Degré de pureté :>99.99%Couleur et forme :SoildMasse moléculaire :343.37Tubulin Polymerization-IN-1 prodrug
CAS :<p>Tubulin Polymerization-IN-1 prodrug (Compound 2b) is a microtubule polymerization inhibitor prodrug mediated by Pd. Developed from colchicine-binding site inhibitors (CBSIs), it aims to reduce toxicity and enhance targeted release. Compared to the parent compound, its cytotoxicity is decreased by 68.3 times, but can be in situ restored in the presence of Pd resin. Mechanistic studies show it retains the same antitumor activity as CBSIs. In vivo tests demonstrate that, once activated by Pd resin, it significantly suppresses tumor growth (63.2% inhibition rate). Tubulin Polymerization-IN-1 prodrug is a promising candidate for cancer research.</p>Formule :C22H23FN2O4Couleur et forme :SolidMasse moléculaire :398.437-Epi-docetaxel
CAS :<p>7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.</p>Formule :C43H53NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :807.88Epothilone F
CAS :<p>Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.</p>Formule :C27H41NO7SCouleur et forme :SolidMasse moléculaire :523.68Cy5-Paclitaxel
Cy5-Paclitaxel is a Cy5-labeled paclitaxel conjugate. Cy5 is a cyanine dye (with an approximate wavelength of 662 nm) utilized in molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization, causing mitotic arrest and apoptotic death. It also induces autophagy.Formule :C93H104N4O16Masse moléculaire :1533.84Aβ-IN-1 TFA
<p>Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.</p>Formule :C37H50F3NO2Degré de pureté :99.82%Couleur et forme :SoildMasse moléculaire :597.79Vinflunine Tartrate
CAS :<p>Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.</p>Formule :C45H54F2N4O8·xC4H6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :967.02PM050489
CAS :<p>PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.</p>Formule :C31H44ClN3O7Couleur et forme :SolidMasse moléculaire :606.15Anticancer agent 270
<p>Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.</p>Couleur et forme :Odour Solid10-Oxo Docetaxel
CAS :<p>10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.</p>Formule :C43H51NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.874Phomopsinamine
CAS :<p>Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).</p>Formule :C32H43ClN6O8Couleur et forme :SolidMasse moléculaire :675.17Tubulin inhibitor 21
<p>Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.</p>Formule :C28H25N3O4SCouleur et forme :SolidMasse moléculaire :499.58N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
CAS :<p>N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM</p>Formule :C24H18ClN3ODegré de pureté :99.93%Couleur et forme :SoildMasse moléculaire :399.87Tubulin polymerization-IN-50
<p>Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell</p>Formule :C24H20FN3O3Couleur et forme :SolidMasse moléculaire :417.43T-808
CAS :<p>T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.</p>Formule :C17H19FN4Couleur et forme :SolidMasse moléculaire :298.36KGP591
<p>KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structure</p>Formule :C24H21NO5Couleur et forme :SolidMasse moléculaire :403.43Tubulin inhibitor 50
<p>Tubulin inhibitor 50 (compound 07) is a microtubule protein inhibitor that enhances mitochondrial reactive oxygen species levels. It exhibits anticancer activity in HeLa cells with an IC50 value of 0.46 μM, while showing low toxicity in normal cell lines.</p>Formule :C16H10ClFN2O2Couleur et forme :SolidMasse moléculaire :316.04148Tubulin polymerization-IN-78
<p>Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.</p>Couleur et forme :Odour SolidTubulin inhibitor 36
<p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>Formule :C16H13ClN6SCouleur et forme :SolidMasse moléculaire :356.83Tubulin polymerization-IN-48
<p>Tubulin polymerization-IN-48 (Compound 4k) is an inhibitor of tubulin polymerization, moderately disrupting the microtubule network.</p>Formule :C20H15Cl2N3OCouleur et forme :SolidMasse moléculaire :384.26Tubulin inhibitor 37
<p>Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cell</p>Formule :C16H10Cl2N6OCouleur et forme :SolidMasse moléculaire :373.2Modified MMAF
CAS :<p>Modified MMAF, an ADC cytotoxin, aids in ADC synthesis for targeted cancer research.</p>Formule :C45H73N7O8Couleur et forme :SolidMasse moléculaire :840.1Tubulin polymerization-IN-46
<p>Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast</p>Formule :C22H25NO6Couleur et forme :SolidMasse moléculaire :399.4420-O-Demethyl-AP3
CAS :<p>20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.</p>Formule :C31H41ClN2O9Couleur et forme :SolidMasse moléculaire :621.12PhosTAC7
CAS :<p>PhosTAC7 successfully induced ternary protein complex formation of Halo-FOXO3a in a dose-dependent manner.</p>Formule :C58H87ClN2O17Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :1119.77TTBK1-IN-1
CAS :<p>TTBK1-IN-1 (compound 31) is a potent and selective TTBK1 inhibitor with CNS penetration that inhibits tau phosphorylation , Alzheimer's disease.</p>Formule :C18H19N5O2Couleur et forme :SolidMasse moléculaire :337.38Tirbanibulin dihydrochloride
CAS :<p>Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Formule :C26H31Cl2N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.45Trifluralin
CAS :<p>Trifluralin (Treflan) is an agricultural herbicide with mild toxicity. Trifluralin is a novel pollutant that can interfere with mitochondrial respiration.</p>Formule :C13H16F3N3O4Degré de pureté :99.84%Couleur et forme :Yellow-Orange Crystalline SolidMasse moléculaire :335.28colchiceine
CAS :<p>colchiceine has a wide range of applications in life science related research.</p>Formule :C21H23NO6Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :385.41Ombrabulin hydrochloride
CAS :<p>Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and</p>Formule :C21H27ClN2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.9BSc3094
CAS :<p>BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.</p>Formule :C17H12N6O3SCouleur et forme :SolidMasse moléculaire :380.38Amiprofos methyl
CAS :<p>Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.</p>Formule :C11H17N2O4PSDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :304.30Oryzalin
CAS :<p>Oryzalin is a selective pre-emergence herbicide belonging to the dinitroaniline class, which exerts its effect by inhibiting cell division in weeds.</p>Formule :C12H18N4O6SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :346.36Avanbulin
CAS :<p>Avanbulin hinders tubulin polymerization, has unique antitumor properties, and is effective against various human tumors at low concentrations.</p>Formule :C20H17N7O2Couleur et forme :SolidMasse moléculaire :387.39TN-16
CAS :<p>TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)</p>Formule :C19H18N2O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :306.36Spastazoline
CAS :<p>Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).</p>Formule :C20H30N8Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :382.51Vindesine sulfate
CAS :<p>Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.</p>Formule :C43H57N5O11SDegré de pureté :97.51%Couleur et forme :Amorphous SolidMasse moléculaire :852N-Phenylbenzylamine
CAS :<p>A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization</p>Formule :C13H13NDegré de pureté :98.75%Couleur et forme :Colorless To Pale Yellow Crystalline PowderMasse moléculaire :183.25Albendazole sulfoxide
CAS :Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.Formule :C12H15N3O3SDegré de pureté :97.29%Couleur et forme :White To Off-White PowderMasse moléculaire :281.33Tau protein (592-597), Human TFA
<p>Tau protein (592-597), Human (TFA) is a peptide fragment of human Tau protein.</p>Formule :C36H63F3N10O11Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :868.94Plinabulin
CAS :<p>Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM).</p>Formule :C19H20N4O2Degré de pureté :98.69% - >99.99%Couleur et forme :SolidMasse moléculaire :336.39MMAF
CAS :<p>MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.</p>Formule :C39H65N5O8Degré de pureté :97.00% - 99.88%Couleur et forme :SolidMasse moléculaire :731.96MAP4343
CAS :<p>Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.</p>Formule :C22H34O2Degré de pureté :97.024%Couleur et forme :SolidMasse moléculaire :330.5Suprafenacine
CAS :<p>Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces</p>Formule :C16H18N4ODegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :282.34Parbendazole
CAS :<p>Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine.</p>Formule :C13H17N3O2Degré de pureté :99.60%Couleur et forme :Physical Description Crystals Or Fine White Powder (Ntp 1992)Masse moléculaire :247.29D-64131
CAS :<p>D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.</p>Formule :C16H13NO2Degré de pureté :99.48% - 99.67%Couleur et forme :SolidMasse moléculaire :251.28
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