Microtubules associés
Les inhibiteurs des protéines associées aux microtubules ciblent les protéines qui interagissent avec les microtubules, les composants structurels du cytosquelette de la cellule qui sont essentiels à la division cellulaire. Ces protéines régulent la stabilité et la dynamique des microtubules pendant la mitose. L'inhibition des protéines associées aux microtubules peut perturber la fonction des microtubules, entraînant un arrêt du cycle cellulaire et l'apoptose, en particulier dans les cellules cancéreuses à division rapide. Ces inhibiteurs sont largement utilisés dans la recherche sur le cancer et le développement de médicaments. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de protéines associées aux microtubules de haute qualité pour soutenir vos recherches sur la division cellulaire, la dynamique du cytosquelette et la thérapie contre le cancer.
261 produits trouvés pour "Microtubules associés"
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Bepranemab
CAS :<p>Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.</p>Degré de pureté :99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Couleur et forme :LiquidTilavonemab
CAS :<p>Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.</p>Degré de pureté :95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Couleur et forme :LiquidZagotenemab
CAS :<p>Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.</p>Degré de pureté :95% - > 95%Couleur et forme :LiquidMasse moléculaire :145.3 kDaTirbanibulin Mesylate
CAS :<p>Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Formule :C27H33N3O6SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :527.63Verubulin hydrochloride
CAS :<p>Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic</p>Formule :C17H18ClN3ODegré de pureté :98.29% - 99.77%Couleur et forme :SolidMasse moléculaire :315.8BNC105
CAS :<p>BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.</p>Formule :C20H20O7Degré de pureté :96.57%Couleur et forme :SolidMasse moléculaire :372.37Entasobulin
CAS :<p>Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.</p>Formule :C26H18ClN3O2Degré de pureté :98.40%Couleur et forme :SolidMasse moléculaire :439.89DM4
CAS :<p>DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.</p>Formule :C38H54ClN3O10SDegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :780.37AC 7739
CAS :<p>AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.</p>Formule :C18H22ClNO4Degré de pureté :99.38% - 99.55%Couleur et forme :SoildMasse moléculaire :351.83Tubulin inhibitor 6
CAS :<p>Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.</p>Formule :C20H14ClNO2SDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :367.85TNIR7-1A
CAS :<p>TNIR7-1A is a fused cycloheptatriene-BODIPY derivative that is optimized for near-infrared (NIR) imaging characteristics (Ex/Em = 600/774 nm in PBS) and exhibits high affinity and specificity for neurofibrillary tangles (NFT) in vitro. Additionally, TNIR7-1A can effectively penetrate the blood-brain barrier.</p>Formule :C23H20BF2N3Couleur et forme :SolidMasse moléculaire :387.23Tubulin inhibitor 24
CAS :<p>Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.</p>Formule :C22H21N3O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :375.42Anticancer agent 270
<p>Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.</p>Couleur et forme :Odour SolidTTBK1-IN-2
CAS :<p>TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.</p>Formule :C18H13ClN4ODegré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :336.77Pironetin
CAS :<p>Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.</p>Formule :C19H32O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.45Sudocetaxel
CAS :<p>Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel.</p>Formule :C48H59NO16Couleur et forme :SolidMasse moléculaire :905.98Tubulin polymerization-IN-44
<p>Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it</p>Formule :C19H15Cl2N3O3SCouleur et forme :SolidMasse moléculaire :436.31Tubulin inhibitor 21
<p>Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.</p>Formule :C28H25N3O4SCouleur et forme :SolidMasse moléculaire :499.58PM050489
CAS :<p>PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.</p>Formule :C31H44ClN3O7Couleur et forme :SolidMasse moléculaire :606.15Tubulin inhibitor 48
CAS :<p>Tubulin inhibitor 48 (compound 16) is an anticancer agent targeting microtubules. It exhibits IC50 values of 0.1 μM and 0.07 μM against LN-229 and Capan-1 cells, respectively.</p>Formule :C21H22N4OCouleur et forme :SolidMasse moléculaire :346.43Larotaxel dihydrate
CAS :<p>Larotaxel dihydrate possesses antineoplastic activity.</p>Formule :C45H57NO16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :867.93Tubulin polymerization-IN-53
<p>Tubulin polymerization-IN-53 (compound 4b) serves as an inhibitor of β-tubulin polymerization and is capable of arresting the cell cycle at the G2/M stage.</p>Couleur et forme :Odour SolidAnticancer agent 139
<p>Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating high</p>Formule :C16H12F3N3OCouleur et forme :SolidMasse moléculaire :319.28Microtubule stabilizing agent-1
<p>Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [</p>Formule :C45H55NO13Couleur et forme :SolidMasse moléculaire :817.92PROTAC tubulin-Degrader-1
<p>PROTAC tubulin-Degrader-1 (Compound W13) functions as an inhibitor of PROTAC tubulin and exhibits anti-tumor activity against human lung cancer.</p>Couleur et forme :Odour SolidVinzolidine
CAS :<p>Vinzolidine is a semi-synthetic vinca alkaloid. It exerts cytotoxic effects on tumor cells by inhibiting cell division through disruption of tubulin polymerization. Vinzolidine can be utilized in research to investigate synergy with other chemotherapy or biotherapy drugs, as well as cancer cell tolerance or resistance, and to explore strategies to overcome these challenges.</p>Formule :C48H58ClN5O9Couleur et forme :SolidMasse moléculaire :884.46KIF18A-IN-12
CAS :<p>KIF18A-IN-12 (compound 9), a potent KIF18A inhibitor, exhibits an IC 50 of 45.54 nM and is utilized in cancer research.</p>Formule :C30H39F2N5O4SCouleur et forme :SolidMasse moléculaire :603.72Tubulin inhibitor 50
<p>Tubulin inhibitor 50 (compound 07) is a microtubule protein inhibitor that enhances mitochondrial reactive oxygen species levels. It exhibits anticancer activity in HeLa cells with an IC50 value of 0.46 μM, while showing low toxicity in normal cell lines.</p>Formule :C16H10ClFN2O2Couleur et forme :SolidMasse moléculaire :316.04148TBL-100
<p>TBL-100 is a human monoclonal antibody (mAb) that targets Tau. It is applicable for research in Alzheimer's disease (AD) and progressive supranuclear palsy.</p>Couleur et forme :Odour LiquidAntiproliferative agent-66
Antiproliferative agent-66 (Compound B3) is an antiproliferative compound that induces apoptosis and causes cell cycle arrest. It demonstrates IC50 values ranging from 2.03 to 3.6 µM against SH-SY5Y neuroblastoma, HT-29 colorectal adenocarcinoma, and fibroblasts. Additionally, Antiproliferative agent-66 functions as a microtubule polymerization inhibitor with an IC50 of 0.79 µM.Formule :C18H15N3SCouleur et forme :SolidMasse moléculaire :305.397ALB-109564 dihydrochloride
CAS :<p>ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.</p>Formule :C47H62Cl2N4O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :929.99T-808
CAS :<p>T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.</p>Formule :C17H19FN4Couleur et forme :SolidMasse moléculaire :298.36KGP591
<p>KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structure</p>Formule :C24H21NO5Couleur et forme :SolidMasse moléculaire :403.43Combretastatin A-1 phosphate tetrasodium
CAS :<p>OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.</p>Formule :C18H18Na4O12P2Couleur et forme :SolidMasse moléculaire :580.24cis-trismethoxy Resveratrol
CAS :<p>cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.</p>Formule :C17H18O3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :270.32Dihydrocephalomannine
CAS :<p>Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.</p>Formule :C45H55NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :833.928Trimethylcolchicinic acid
CAS :<p>Trimethylcolchicinic acid is an orally available colchicine analog that binds to tubulin and inhibits its polymerization into microtubules,potential antitumor.</p>Formule :C19H21NO5Degré de pureté :>99.99%Couleur et forme :SoildMasse moléculaire :343.3720-O-Demethyl-AP3
CAS :<p>20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.</p>Formule :C31H41ClN2O9Couleur et forme :SolidMasse moléculaire :621.12Tubulin inhibitor 38
<p>Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell</p>Formule :C17H13ClN6OSCouleur et forme :SolidMasse moléculaire :384.84MT189
CAS :<p>MT189 (Antiproliferative agent-14) inhibits tubulin polymerization (IC50 3.41 μM), arrests G2/M cell cycle, and is highly antiproliferative.</p>Formule :C21H18FN3O2Degré de pureté :98.52%Couleur et forme :SoildMasse moléculaire :363.38Phomopsin A
CAS :<p>Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.</p>Formule :C36H45ClN6O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :789.23Tubulin polymerization-IN-78
<p>Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.</p>Couleur et forme :Odour SolidEpothilone F
CAS :<p>Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.</p>Formule :C27H41NO7SCouleur et forme :SolidMasse moléculaire :523.68KIF18A-IN-2
CAS :<p>KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.</p>Formule :C25H34N4O5S2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :534.69Cys-McMMAF
CAS :<p>Cys-McMMAF, a microtubule-disrupting agent linked to an anti-5T4 antibody, shows antitumor effects in mouse models.</p>Formule :C52H83N7O13SCouleur et forme :SolidMasse moléculaire :1046.3210-Oxo Docetaxel
CAS :<p>10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.</p>Formule :C43H51NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.874Aβ-IN-1 TFA
<p>Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.</p>Formule :C37H50F3NO2Degré de pureté :99.82%Couleur et forme :SoildMasse moléculaire :597.79Tubulin polymerization-IN-50
<p>Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell</p>Formule :C24H20FN3O3Couleur et forme :SolidMasse moléculaire :417.43Microtubule destabilizing agent-1
CAS :<p>Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.</p>Formule :C22H26N4O4Couleur et forme :SolidMasse moléculaire :410.47Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Formule :C83H127N25O34SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2051.11Tubulin inhibitor 36
<p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>Formule :C16H13ClN6SCouleur et forme :SolidMasse moléculaire :356.83N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
CAS :<p>N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM</p>Formule :C24H18ClN3ODegré de pureté :99.93%Couleur et forme :SoildMasse moléculaire :399.87Tubulin polymerization-IN-46
<p>Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast</p>Formule :C22H25NO6Couleur et forme :SolidMasse moléculaire :399.44Vinflunine Tartrate
CAS :<p>Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.</p>Formule :C45H54F2N4O8·xC4H6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :967.02Bifidenone
CAS :<p>Bifidenone is an effective tubulin polymerization inhibitor.</p>Formule :C21H26O5Couleur et forme :SolidMasse moléculaire :358.43Diminutol
CAS :<p>Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.</p>Formule :C19H26N6OSCouleur et forme :SolidMasse moléculaire :386.51Tubulin polymerization-IN-47
CAS :<p>Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer</p>Formule :C22H21N3O3Degré de pureté :99.64%Couleur et forme :SoildMasse moléculaire :375.42Ceratamine A
CAS :<p>Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.</p>Formule :C17H16Br2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.14SPA107
CAS :<p>SPA107 (Hemiasterlin methyl ester) is an analogue of Hemiasterlin. It inhibits tubulin polymerization, exhibiting antimitotic activity with an IC50 of 0.5 nM. SPA107 also shows cytotoxicity against p53 mutated MCF-7 cells, with an IC50 of 0.5 nM.</p>Formule :C31H48N4O4Couleur et forme :SolidMasse moléculaire :540.74Anti-α-Tubulin Antibody, AF555 conjugate
<p>Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for the</p>Couleur et forme :SolidTubulin Polymerization-IN-1 prodrug
CAS :<p>Tubulin Polymerization-IN-1 prodrug (Compound 2b) is a microtubule polymerization inhibitor prodrug mediated by Pd. Developed from colchicine-binding site inhibitors (CBSIs), it aims to reduce toxicity and enhance targeted release. Compared to the parent compound, its cytotoxicity is decreased by 68.3 times, but can be in situ restored in the presence of Pd resin. Mechanistic studies show it retains the same antitumor activity as CBSIs. In vivo tests demonstrate that, once activated by Pd resin, it significantly suppresses tumor growth (63.2% inhibition rate). Tubulin Polymerization-IN-1 prodrug is a promising candidate for cancer research.</p>Formule :C22H23FN2O4Couleur et forme :SolidMasse moléculaire :398.43Tubulin polymerization-IN-55
CAS :<p>Tubulin polymerisation-IN-55 is a Tubulin Polymerization inhibitor that displays antiproliferative effects on A549, K562, HepG2, MDA-MB-231 and HFL-1.</p>Formule :C22H24N2O4Degré de pureté :98.68%Couleur et forme :SoildMasse moléculaire :380.44Tubulin polymerization-IN-69
<p>Tubulin polymerization-IN-69 (compound 6c) exhibits significant inhibition of microtubule assembly in vitro, with an inhibition rate of 78.3% and an IC50 value of 6.53 μM. It rapidly induces apoptosis and G2/M phase cell cycle arrest in MCF-7 cells.</p>Couleur et forme :Odour SolidT-900607
CAS :<p>T-900607 is a novel microtubule protein active agent that disrupts microtubule polymerization through a unique mechanism of action. t-900607 is cardiotoxic.</p>Formule :C14H10F5N3O4SDegré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :411.37-Epi-docetaxel
CAS :<p>7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.</p>Formule :C43H53NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :807.88Phomopsinamine
CAS :<p>Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).</p>Formule :C32H43ClN6O8Couleur et forme :SolidMasse moléculaire :675.17Vinblastine
CAS :<p>Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.</p>Formule :C46H58N4O9Degré de pureté :97.42%Couleur et forme :PowderMasse moléculaire :810.97Alestramustine
CAS :<p>Alestramustine: a cancer drug that targets microtubules in estrogen receptor-positive cells, impeding cell division.</p>Formule :C26H36Cl2N2O4Couleur et forme :SolidMasse moléculaire :511.48Modified MMAF
CAS :<p>Modified MMAF, an ADC cytotoxin, aids in ADC synthesis for targeted cancer research.</p>Formule :C45H73N7O8Couleur et forme :SolidMasse moléculaire :840.17-Epi-10-oxo-docetaxel
CAS :<p>7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.</p>Formule :C43H51NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.86Tubulin inhibitor 37
<p>Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cell</p>Formule :C16H10Cl2N6OCouleur et forme :SolidMasse moléculaire :373.2AADvac 1 TFA
AADvac 1 TFA is an active tau peptide vaccine utilized in Alzheimer's disease research. It is formed by conjugating the regulatory peptide 294KDNIKHVPGGGS305, which drives tau oligomerization, with keyhole limpet hemocyanin (KLH), and is formulated with aluminum hydroxide.Tubulin/PARP-IN-1
<p>Tubulin/PARP-IN-1 (compound 14) is a dual PARP-tubulin inhibitor with anti-endometrial cancer activity. It exhibits inhibitory concentration (IC50) values of 74 nM for PARP1, 109 nM for PARP2, and 1.4 μM for microtubules/tubulin. Tubulin/PARP-IN-1 induces apoptosis and autophagy, causing cell cycle arrest at the G2/M phase.</p>Formule :C19H13FO3Masse moléculaire :308.08487Tubulin inhibitor 45
<p>Tubulin inhibitor 45 (compound 5) functions as an inhibitor of the active site of tubulin. It exhibits IC50 values of 11 μM for MCF7 cancer cells and 13 μM for HePG2 cancer cells.</p>Formule :C19H18N2O2SMasse moléculaire :338.1089Tubulin polymerization-IN-49
<p>Tubulin polymerization-IN-49 (compound 12d), a potent inhibitor of tubulin polymerization, binds to the colchicine site on tubulin, subsequently inducing cell</p>Formule :C20H24O5Couleur et forme :SolidMasse moléculaire :344.4Anhydrovinblastine sulfate
<p>Anhydrovinblastine sulfate is a monoterpene indole alkaloid that can be extracted from the leaves of Catharanthus roseus.</p>Formule :C46H60N4O16S2Masse moléculaire :988.34457Tubulin polymerization-IN-48
<p>Tubulin polymerization-IN-48 (Compound 4k) is an inhibitor of tubulin polymerization, moderately disrupting the microtubule network.</p>Formule :C20H15Cl2N3OCouleur et forme :SolidMasse moléculaire :384.26Trifluralin
CAS :<p>Trifluralin (Treflan) is an agricultural herbicide with mild toxicity. Trifluralin is a novel pollutant that can interfere with mitochondrial respiration.</p>Formule :C13H16F3N3O4Degré de pureté :99.84%Couleur et forme :Yellow-Orange Crystalline SolidMasse moléculaire :335.28TTBK1-IN-1
CAS :<p>TTBK1-IN-1 (compound 31) is a potent and selective TTBK1 inhibitor with CNS penetration that inhibits tau phosphorylation , Alzheimer's disease.</p>Formule :C18H19N5O2Couleur et forme :SolidMasse moléculaire :337.38Oryzalin
CAS :<p>Oryzalin is a selective pre-emergence herbicide belonging to the dinitroaniline class, which exerts its effect by inhibiting cell division in weeds.</p>Formule :C12H18N4O6SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :346.36BSc3094
CAS :<p>BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.</p>Formule :C17H12N6O3SCouleur et forme :SolidMasse moléculaire :380.38Amiprofos methyl
CAS :<p>Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.</p>Formule :C11H17N2O4PSDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :304.30PhosTAC7
CAS :<p>PhosTAC7 successfully induced ternary protein complex formation of Halo-FOXO3a in a dose-dependent manner.</p>Formule :C58H87ClN2O17Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :1119.77Tirbanibulin dihydrochloride
CAS :<p>Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Formule :C26H31Cl2N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.45colchiceine
CAS :<p>colchiceine has a wide range of applications in life science related research.</p>Formule :C21H23NO6Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :385.41Avanbulin
CAS :<p>Avanbulin hinders tubulin polymerization, has unique antitumor properties, and is effective against various human tumors at low concentrations.</p>Formule :C20H17N7O2Couleur et forme :SolidMasse moléculaire :387.39Ombrabulin hydrochloride
CAS :<p>Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and</p>Formule :C21H27ClN2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.9D-64131
CAS :<p>D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.</p>Formule :C16H13NO2Degré de pureté :99.48% - 99.67%Couleur et forme :SolidMasse moléculaire :251.28Soblidotin
CAS :<p>Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.</p>Formule :C39H67N5O6Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :701.98Curvulin
CAS :<p>Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.</p>Formule :C12H14O5Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :238.24Plinabulin
CAS :<p>Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM).</p>Formule :C19H20N4O2Degré de pureté :98.69% - >99.99%Couleur et forme :SolidMasse moléculaire :336.39LP-261
CAS :<p>LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.</p>Formule :C22H19N3O4SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :421.47Parbendazole
CAS :<p>Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine.</p>Formule :C13H17N3O2Degré de pureté :99.60%Couleur et forme :Physical Description Crystals Or Fine White Powder (Ntp 1992)Masse moléculaire :247.29T807
CAS :<p>T807 (AV-1451) is a novel tracer of tau positron emission tomography (PET).</p>Formule :C16H10FN3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :263.27Valecobulin
CAS :<p>Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.</p>Formule :C26H28N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :536.6Tau protein (592-597), Human TFA
<p>Tau protein (592-597), Human (TFA) is a peptide fragment of human Tau protein.</p>Formule :C36H63F3N10O11Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :868.94Tirbanibulin
CAS :<p>Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.</p>Formule :C26H29N3O3Degré de pureté :99.43% - 99.67%Couleur et forme :SolidMasse moléculaire :431.53TN-16
CAS :<p>TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)</p>Formule :C19H18N2O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :306.36N-Phenylbenzylamine
CAS :<p>A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization</p>Formule :C13H13NDegré de pureté :98.75%Couleur et forme :Colorless To Pale Yellow Crystalline PowderMasse moléculaire :183.25MAP4343
CAS :<p>Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.</p>Formule :C22H34O2Degré de pureté :97.024%Couleur et forme :SolidMasse moléculaire :330.5MMAD
CAS :<p>MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).</p>Formule :C41H66N6O6SDegré de pureté :99.25% - 99.91%Couleur et forme :SolidMasse moléculaire :771.06MMAF
CAS :<p>MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.</p>Formule :C39H65N5O8Degré de pureté :97.00% - 99.88%Couleur et forme :SolidMasse moléculaire :731.96Estramustine
CAS :<p>Estramustine (LEO-275), a nitrogen mustard-estradiol compound, treats prostate cancer and protects against radiation.</p>Formule :C23H31Cl2NO3Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :440.4Albendazole sulfoxide
CAS :Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.Formule :C12H15N3O3SDegré de pureté :97.29%Couleur et forme :White To Off-White PowderMasse moléculaire :281.33Suprafenacine
CAS :<p>Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces</p>Formule :C16H18N4ODegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :282.34Vindesine sulfate
CAS :<p>Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.</p>Formule :C43H57N5O11SDegré de pureté :97.51%Couleur et forme :Amorphous SolidMasse moléculaire :852Spastazoline
CAS :<p>Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).</p>Formule :C20H30N8Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :382.51Clanfenur
CAS :<p>Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.</p>Formule :C16H15ClFN3O2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :335.764-Isopropoxybenzoic acid
CAS :<p>4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.</p>Formule :C10H12O3Degré de pureté :99.88%Couleur et forme :White To Off-White PowderMasse moléculaire :180.2NQTrp
CAS :<p>NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.</p>Formule :C21H16N2O4Degré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :360.364-Desacetylvinblastine hydrazide
CAS :<p>Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.</p>Formule :C43H56N6O7Couleur et forme :SolidMasse moléculaire :768.94Gosuranemab
CAS :<p>Gosuranemab (BMS-986168), a humanized IgG4 mAb, targets tau residues 15-22, and may aid in Alzheimer’s research.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidPosdinemab
CAS :<p>Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].</p>Couleur et forme :LiquidSemorinemab
CAS :<p>Semorinemab (RG6100) is a humanised monoclonal antibody targeting the N-terminal domain of tau protein with a Kd of 3.8 nM, suitable for Alzheimer's disease.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidST-401
CAS :<p>ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.</p>Formule :C24H20N2OCouleur et forme :SolidMasse moléculaire :352.43Tubulin polymerization-IN-2
CAS :<p>Tubulin-IN-2, anticancer β-tubulin binder, IC50 0.92 μM, effective against various cancers.</p>Formule :C17H12F2N2O2Couleur et forme :SolidMasse moléculaire :314.29Auristatin F
CAS :<p>Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.</p>Formule :C40H67N5O8Degré de pureté :98.41% - 99.25%Couleur et forme :SolidMasse moléculaire :745.99Sabeluzole
CAS :<p>Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.</p>Formule :C22H26FN3O2SDegré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :415.52AM-5308
CAS :<p>AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.</p>Formule :C26H35N5O5SDegré de pureté :98.06% - 99.58%Couleur et forme :SolidMasse moléculaire :529.65Tau protein aggregation-IN-1
CAS :<p>Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders</p>Formule :C17H11BrN2O2Couleur et forme :SolidMasse moléculaire :355.19OSIP-486823
CAS :<p>OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.</p>Formule :C29H28FNO4Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :473.54IQTub4P
CAS :<p>IQTub4P is a potent inhibitor of microtubules. IQTub4P exhibits cytotoxicity in HeLa cells (EC50: 170 nM).</p>Formule :C19H18NNa2O8PCouleur et forme :SolidMasse moléculaire :465.305Tubulin polymerization-IN-42
CAS :<p>Tubulin polymerization-IN-42 (compound 10j), an indole-substituted furanone, inhibits tubulin polymerization and exhibits anti-cancer properties [1].</p>Formule :C22H21NO5Couleur et forme :SolidMasse moléculaire :379.41Alyssin
CAS :<p>Alyssin: sulforaphane analog, antioxidant; boosts Nrf2 and phase II enzymes in cancer cells; lowers PAH metabolism, reducing cancer risk in vitro.</p>Formule :C7H13NOS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :191.31Tubulozole
CAS :<p>Tubulozole blocks mitosis by inhibiting microtubule dynamics, leading to cell cycle arrest and apoptosis.</p>Formule :C23H23Cl2N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :508.42Sirt1/2-IN-1
CAS :<p>Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.</p>Formule :C22H13ClN2OS2Couleur et forme :SolidMasse moléculaire :420.93Amphethinile
CAS :<p>Amphethinile is an anti-tubulin agent. The Ka of Amphethinile with tubulin is 1.3 μM.</p>Formule :C15H11N3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :265.33Microtubule inhibitor 3
CAS :<p>Compounds 17o and 17p with furan have IC50s of 14.0 and 2.9 nM, respectively, against NCI-H460 cancer cells.</p>Formule :C26H23FN4O3Couleur et forme :SolidMasse moléculaire :458.48Microtubule inhibitor 1
CAS :<p>Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity(IC50 = 9-16 nM, in cancer cells).</p>Formule :C21H19NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.38Anticancer agent 48
CAS :<p>Compound 48: broad-spectrum, anti-proliferative, inhibits microtubules, active in vivo, with potential for tumor research.</p>Formule :C26H25N3O4Couleur et forme :SolidMasse moléculaire :443.49Tubulin polymerization-IN-39
<p>Tubulin-IN-39 inhibits polymerization (IC50: 4.9 μM), blocks colchicine site, stops cancer growth.</p>Formule :C21H21N5O5Couleur et forme :SolidMasse moléculaire :423.42Tubulin inhibitor 28
CAS :<p>Compound 2g, a tubulin inhibitor with an IC50 of 1.2 μM, inhibits MCF-7 cell proliferation.</p>Formule :C12H8Br2S2Couleur et forme :SolidMasse moléculaire :376.13Tubulin inhibitor 7
CAS :<p>Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (</p>Formule :C21H14N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :358.35MT-7
CAS :<p>MT-7 is a tubulin polymerization inhibitor.</p>Formule :C22H17N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.39Anticancer agent 49
CAS :<p>Anticancer agent 49, also 69, hinders cell growth and microtubule aggregation, with potential in solid and blood cancer research.</p>Formule :C26H25N3O4Couleur et forme :SolidMasse moléculaire :443.49Tubulin polymerization-IN-19
CAS :<p>Tubulin aggregation-IN-19 (compound 4) is a potent tubulin aggregation inhibitor that has shown potential in breast cancer and drug-resistant colon cancer.</p>Formule :C25H25NO5Couleur et forme :SolidMasse moléculaire :419.47DJ101
CAS :<p>DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.</p>Formule :C23H20N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.43Tubulin polymerization-IN-27
CAS :<p>Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.</p>Formule :C22H20N2O2Couleur et forme :SolidMasse moléculaire :344.41Aha1/Hsp90-IN-1
CAS :<p>Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.</p>Formule :C22H17F3N4O2Couleur et forme :SolidMasse moléculaire :426.39MG-2119
CAS :<p>MG-2119 is a potent inhibitor of monomeric tau and α-syn aggregation and can be used to study neurological diseases.</p>Formule :C27H29N5O4Couleur et forme :SolidMasse moléculaire :487.55isoCA-4
CAS :<p>isoCA-4 is a Combretastatin A4 derivative. isoCA-4 is a tubulin polymerization inhibitor with anti-proliferative activities [1].</p>Formule :C18H20O5Couleur et forme :SolidMasse moléculaire :316.35Tubulin polymerization-IN-29
CAS :<p>Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.</p>Formule :C25H20FNO6Couleur et forme :SolidMasse moléculaire :449.43BNC105P
CAS :<p>BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.</p>Formule :C20H21O10PCouleur et forme :SolidMasse moléculaire :452.3485Microtubule inhibitor 4
CAS :<p>Microtubule inhibitor 4 (Compound 2) blocks polymerization, toxic to HT-29 cells (IC50: 2.1 nM).</p>Formule :C25H23FN4O3Couleur et forme :SolidMasse moléculaire :446.47Tubulin inhibitor 27
CAS :<p>DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.</p>Formule :C21H19NO4Couleur et forme :SolidMasse moléculaire :349.38Tubulin polymerization-IN-21
CAS :<p>Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.</p>Formule :C30H29NO7Couleur et forme :SolidMasse moléculaire :515.55Tubulin polymerization-IN-10
CAS :<p>Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.</p>Formule :C18H21NO6SCouleur et forme :SolidMasse moléculaire :379.43Neuroinflammatory-IN-3
CAS :<p>Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.</p>Formule :C19H19ClO3Couleur et forme :SolidMasse moléculaire :330.81Tubulin polymerization-IN-36
CAS :<p>Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.</p>Formule :C18H18N2O3Couleur et forme :SolidMasse moléculaire :310.35Tubulin polymerization-IN-16
CAS :<p>Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.</p>Formule :C24H27N5O5Couleur et forme :SolidMasse moléculaire :465.5O-GlcNAcase-IN-4
CAS :<p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>Formule :C16H22FN5O3SCouleur et forme :SolidMasse moléculaire :383.44Tubulin polymerization-IN-18
CAS :<p>Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.</p>Formule :C25H25NO6Couleur et forme :SolidMasse moléculaire :435.47Synstab A
CAS :<p>Synstab A is a microtubule stabilizer.</p>Formule :C15H13BrCl3N3O3SCouleur et forme :SolidMasse moléculaire :501.61Microtubule inhibitor 7
CAS :<p>Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.</p>Formule :C25H19FN2O5Couleur et forme :SolidMasse moléculaire :446.43(S)-Dolaphenine hydrochloride
CAS :<p>(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.</p>Formule :C11H13ClN2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :240.75Deox B 7,4
CAS :<p>Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.</p>Formule :C18H18O5Couleur et forme :SolidMasse moléculaire :314.33Tubulin polymerization-IN-30
CAS :<p>Compound 6e inhibits tubulin polymerization, disrupts microtubules, halts G2/M phase, and targets HeLa, SGC-7901, A549 with low IC50.</p>Formule :C22H25N5O3Couleur et forme :SolidMasse moléculaire :407.47Tubulin inhibitor 29
CAS :<p>Compound 3c, a tubulin inhibitor, blocks assembly at colchicine site with IC50 of 1.2 μM; anti-proliferative IC50 7.5 μM in MCF-7 cells.</p>Formule :C12H8F2O2S2Couleur et forme :SolidMasse moléculaire :286.32Microtubule inhibitor 6
CAS :<p>Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.</p>Formule :C24H19FN2O5Couleur et forme :SolidMasse moléculaire :434.42Tubulin inhibitor 31
<p>Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.</p>Formule :C22H19NO2Couleur et forme :SolidMasse moléculaire :329.39Tubulin polymerization-IN-7
CAS :<p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>Formule :C28H24N4O6SCouleur et forme :SolidMasse moléculaire :544.58Anticancer agent 60
CAS :<p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>Formule :C27H33N5O4SCouleur et forme :SolidMasse moléculaire :523.65SB26019
CAS :<p>SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.</p>Formule :C24H20O4Couleur et forme :SolidMasse moléculaire :372.41AMXI-5001
CAS :<p>AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.</p>Formule :C25H20FN5O3Couleur et forme :SolidMasse moléculaire :457.46Tubulin inhibitor 20
CAS :<p>Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].</p>Formule :C19H18O4Couleur et forme :SolidMasse moléculaire :310.34Tubulin inhibitor 26
CAS :<p>Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.</p>Formule :C17H19N3O3Couleur et forme :SolidMasse moléculaire :313.35Microtubule inhibitor 5
CAS :<p>Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.</p>Formule :C22H15FN2O4Couleur et forme :SolidMasse moléculaire :390.36Tubulin polymerization-IN-37
CAS :<p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>Formule :C19H20N2O4Couleur et forme :SolidMasse moléculaire :340.37THK-5117
CAS :<p>THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.</p>Formule :C19H19FN2O2Couleur et forme :SolidMasse moléculaire :326.36OXi8007
CAS :<p>OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.</p>Formule :C26H24NNa2O10PCouleur et forme :SolidMasse moléculaire :587.428Hydromethylthionine HBr
CAS :<p>Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.</p>Formule :C16H21Br2N3SCouleur et forme :SolidMasse moléculaire :447.233(R)-TTBK1-IN-1
CAS :<p>(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s & tauopathies.</p>Formule :C18H19N5O2Couleur et forme :SolidMasse moléculaire :337.38Tubulin polymerization-IN-25
CAS :<p>Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.</p>Formule :C24H18N2O3SCouleur et forme :SolidMasse moléculaire :414.48Tubulin polymerization-IN-15
CAS :<p>Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].</p>Formule :C18H17N3O4Couleur et forme :SolidMasse moléculaire :339.35Tubulin polymerization-IN-20
CAS :<p>Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.</p>Formule :C25H24FNO5Couleur et forme :SolidMasse moléculaire :437.46Tubulin inhibitor 18
CAS :<p>"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."</p>Formule :C22H26O5Couleur et forme :SolidMasse moléculaire :370.44Tubulin/MMP-IN-1
<p>Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.</p>Formule :C38H44NO9PCouleur et forme :SolidMasse moléculaire :689.73Tubulin inhibitor 12
CAS :<p>New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.</p>Formule :C24H20N2OCouleur et forme :SolidMasse moléculaire :352.43Tau tracer 1
CAS :<p>Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.</p>Formule :C34H23N5O2Couleur et forme :SolidMasse moléculaire :533.591Iso-Fludelone
CAS :<p>Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.</p>Formule :C27H36F3NO6Couleur et forme :SolidMasse moléculaire :527.57KIF18A-IN-4
CAS :<p>KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.</p>Formule :C22H27N3O3SCouleur et forme :SolidMasse moléculaire :413.53Antitumor agent-68
CAS :<p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>Formule :C17H11NO2Couleur et forme :SolidMasse moléculaire :261.27Antitumor agent-71
CAS :<p>Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.</p>Formule :C26H31N5O4SCouleur et forme :SolidMasse moléculaire :509.62IDT
CAS :<p>IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.</p>Formule :C8H5NS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.26DHNQ
CAS :<p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>Formule :C18H14N2OCouleur et forme :SolidMasse moléculaire :274.32D011-2120
CAS :<p>D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.</p>Formule :C17H15NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :281.31DAT1
CAS :<p>DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.</p>Formule :C17H15N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.38Acodazole
CAS :<p>Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.</p>Formule :C20H19N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.4Acodazole hydrochloride
CAS :<p>Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.</p>Formule :C20H20ClN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :381.86LDN-193665
CAS :LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Formule :C15H11FN4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :314.34GF 15
CAS :<p>GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.</p>Formule :C23H21ClO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.86TOK-8801
CAS :<p>TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.</p>Formule :C17H21N3OSDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :315.43Mivobulin
CAS :<p>Mivobulin is an inhibitor of tubulin .</p>Formule :C17H19N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.37S-methyl DM1
CAS :<p>S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.</p>Formule :C36H50ClN3O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :752.31Cevipabulin
CAS :<p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>Formule :C18H18ClF5N6ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :464.82Tau-aggregation and neuroinflammation-IN-1
CAS :<p>Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.</p>Formule :C25H20N2O7Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :460.44CCB02
CAS :CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Formule :C14H9N3ODegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :235.24S516
CAS :<p>S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.</p>Formule :C21H19N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :437.47Tubulin inhibitor 8
CAS :<p>Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.</p>Formule :C21H14N2O3Degré de pureté :98.51% - 99.87%Couleur et forme :SolidMasse moléculaire :342.35TCS 2210
CAS :<p>TCS 2210 promotes neuronal differentiation in stem cells, boosting β-III tubulin and enolase markers.</p>Formule :C18H17N3O3Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :323.35
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