ROCK
Les inhibiteurs de la protéine kinase associée à Rho (ROCK) ciblent les kinases ROCK, qui sont impliquées dans la régulation du cytosquelette, de la forme cellulaire et de la motilité. ROCK joue un rôle significatif dans le contrôle de la division cellulaire, notamment dans des processus tels que la cytokinèse. Inhiber ROCK peut entraîner des changements dans la dynamique du cycle cellulaire, la motilité cellulaire et l'apoptose, ce qui rend ces inhibiteurs précieux dans la recherche sur le cancer, la neurobiologie et les études cardiovasculaires. Chez CymitQuimica, nous offrons une sélection d'inhibiteurs de ROCK de haute qualité pour soutenir vos recherches en biologie cellulaire, dynamique du cytosquelette et mécanismes des maladies.
65 produits trouvés pour "ROCK"
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ROCK inhibitor-2
CAS :ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).Formule :C21H20N2O2Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :332.4Ref: TM-T12746
1mg66,00€5mg144,00€10mg216,00€25mg432,00€50mg645,00€100mg905,00€1mL*10mM (DMSO)106,00€Netarsudil Dihydrochloride
CAS :Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-related protein kinase (ROCK) and norepinephrine transporter (NET) and is effective in reducing intraocular pressure (IOP).Cost-effective and quality-assured.Formule :C28H29Cl2N3O3Degré de pureté :99.94% - 99.98%Couleur et forme :SolidMasse moléculaire :526.45Y-33075 dihydrochloride
CAS :Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).Formule :C16H18Cl2N4ODegré de pureté :98.88% - 99.89%Couleur et forme :SolidMasse moléculaire :353.25Ref: TM-T13384L
1mg35,00€5mg70,00€10mg107,00€25mg202,00€50mg360,00€100mg538,00€200mg772,00€1mL*10mM (DMSO)82,00€CMPD101
CAS :CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Formule :C24H21F3N6ODegré de pureté :99.01% - 99.04%Couleur et forme :SolidMasse moléculaire :466.46Akt/ROCK-IN-1
Akt/ROCK-IN-1 (B12) is a dual inhibitor targeting Akt and ROCK, exhibiting IC50 values of 0.023 nM and 1.47 nM, respectively.Formule :C21H19BrF2N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.37RhoA-ROCK-IN-1
RhoA-ROCK-IN-1 (Compound b19) is an inhibitor of the RhoA/ROCK pathway. It significantly inhibits cell proliferation, migration, and invasion, while promoting cell apoptosis (apoptosis). RhoA-ROCK-IN-1 exhibits strong anticancer activities by inhibiting the RhoA/ROCK pathway.Formule :C24H23N3O4SCouleur et forme :SolidMasse moléculaire :449.52WAY-656935
CAS :WAY-656935 inhibits ROCK.Formule :C20H28ClN3O3SDegré de pureté :97%Couleur et forme :SolidMasse moléculaire :425.97LX-7101 hydrochloride
CAS :LX-7101 hydrochloride is a potent LIMK and ROCK2 inhibitor with antihypertensive activity, inhibits LIMK1/2, ROCK, PKA, and can be used to study glaucoma.
Formule :C23H29N7O3xHClDegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :487.99GKI-1 HCl
GKI-1 HCl is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL and hGWL-KinDom.The inhibitory effect of GKI-1 HCl on ROCK1 is more significant.
Formule :C15H13Cl2N3Degré de pureté :98.51%Couleur et forme :SoildMasse moléculaire :306.19ROCK2-IN-9
ROCK2-IN-9 (compound 7u), a selective ROCK2 inhibitor with an IC50 value of 36.8 nM, demonstrates anticancer properties by impeding cancer cell migration and invasion. This action is achieved through the regulation of various actin cytoskeleton cellular activities. It holds potential for use in breast cancer research.Formule :C28H30N8O2Couleur et forme :SolidMasse moléculaire :510.59Fasudil
CAS :Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formule :C14H17N3O2SDegré de pureté :99.79% - 99.84%Couleur et forme :SolidMasse moléculaire :291.37Ripasudil free base
CAS :Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent.Formule :C15H18FN3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.39Ref: TM-T7492
1mg75,00€5mg150,00€10mg238,00€25mg530,00€50mg873,00€100mg1.459,00€1mL*10mM (DMSO)166,00€Verosudil
CAS :Verosudil (AR-12286), a ROCK1/2 inhibitor (Ki: 2 nM), lowers intraocular pressure in mice by enhancing aqueous outflow.Formule :C17H17N3O2SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :327.4Ref: TM-T60924
1mg55,00€5mg147,00€10mg231,00€25mg370,00€50mg522,00€100mg692,00€1mL*10mM (DMSO)161,00€GSK269962A hydrochloride
CAS :GSK269962A hydrochloride (GSK 269962 hydrochloride) is a ROCK inhibitor with anti-inflammatory and vasodilatory effects and inhibits ROCK1 and ROCK2.Formule :C29H31ClN8O5Couleur et forme :SolidMasse moléculaire :607.06Cotosudil
CAS :Cotosudil is a ROCK kinase inhibitor with antihypertensive activity used to treat or prevent neurodegenerative diseases.Formule :C16H21N3O2SDegré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :319.42Belumosudil mesylate
CAS :Belumosudil mesylate (KD025 mesylate) is a ROCK2 inhibitor with antifibrotic activity, and can be used in chronic graft-versus-host disease research.Formule :C27H28N6O5SDegré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :548.61Ref: TM-T39555
1mg35,00€2mg48,00€5mg74,00€10mg92,00€25mg163,00€50mg243,00€100mg373,00€200mg547,00€1mL*10mM (DMSO)89,00€CCG-222740
CAS :CCG-222740 is an inhibitor of Rho/MRTF pathwayFormule :C23H19ClF2N2O3Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :444.86Ref: TM-T7764
2mg42,00€5mg65,00€10mg99,00€25mg182,00€50mg274,00€100mg393,00€200mg560,00€1mL*10mM (DMSO)70,00€RKI-1447
CAS :RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.Formule :C16H14N4O2SDegré de pureté :98% - 99.73%Couleur et forme :SolidMasse moléculaire :326.37Ref: TM-T1898
5mg51,00€10mg87,00€25mg187,00€50mg311,00€100mg414,00€200mg520,00€500mg840,00€1mL*10mM (DMSO)57,00€SR-3677
CAS :SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).Formule :C22H24N4O4Degré de pureté :98.46%Couleur et forme :SolidMasse moléculaire :408.45HA-100
CAS :HA-100 is an inhibitor of protein kinaseFormule :C13H15N3O2SDegré de pureté :99.44%Couleur et forme :Pale Yellow Crystalline SolidMasse moléculaire :277.34RKI1313
CAS :RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasionFormule :C17H16N4O2SDegré de pureté :99.53% - ≥95%Couleur et forme :SolidMasse moléculaire :340.4Ref: TM-T2011
1mg70,00€5mg142,00€10mg207,00€25mg369,00€50mg540,00€100mg772,00€500µg49,00€1mL*10mM (DMSO)160,00€Hydroxyfasudil
CAS :Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).Formule :C14H17N3O3SDegré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :307.37GSK429286A
CAS :GSK429286A (RHO-15) is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM).Formule :C21H16F4N4O2Degré de pureté :97.68% - 98.49%Couleur et forme :SolidMasse moléculaire :432.37SAR407899 hydrochloride
CAS :SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human andFormule :C14H17ClN2O2Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :280.75SAR407899
CAS :SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.Formule :C14H16N2O2Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :244.29Ref: TM-T7391
2mg35,00€5mg52,00€10mg80,00€25mg135,00€50mg210,00€100mg338,00€200mg500,00€1mL*10mM (DMSO)58,00€AT13148
CAS :AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.Formule :C17H16ClN3ODegré de pureté :98.04% - ≥95%Couleur et forme :SolidMasse moléculaire :313.78ROCK-IN-2
CAS :ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.Formule :C18H13ClF2N6ODegré de pureté :97.29%Couleur et forme :SolidMasse moléculaire :402.79Ref: TM-TQ0110
1mg108,00€5mg260,00€10mg416,00€25mg690,00€50mg964,00€100mg1.305,00€1mL*10mM (DMSO)353,00€Narciclasine
CAS :Narciclasine (Lycoricidinol), a natural product, modulates the Rho/Rho-kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity.Formule :C14H13NO7Degré de pureté :98.16% - 99.58%Couleur et forme :SolidMasse moléculaire :307.26ZINC00881524
CAS :ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.
Formule :C21H20N2O3SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :380.46Fasudil hydrochloride
CAS :Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Formule :C14H18ClN3O2SDegré de pureté :99.54% - ≥95%Couleur et forme :White SolidMasse moléculaire :327.83Afuresertib hydrochloride
CAS :Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
Formule :C18H18Cl3FN4OSDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :463.8Hydroxyfasudil Hydrochloride
CAS :Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).Formule :C14H18ClN3O3SDegré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :343.83GSK180736A
CAS :GSK180736A: GRK2 inhibitor (IC50 0.77µM), >100x selectivity vs GRKs, weak at PKA (IC50 30µM), strong vs ROCK1 (IC50 100nM).Formule :C19H16FN5O2Degré de pureté :98.38% - 98.98%Couleur et forme :SolidMasse moléculaire :365.36Ref: TM-T3513
1mg39,00€2mg50,00€5mg70,00€10mg94,00€25mg161,00€50mg290,00€100mg538,00€500mg1.161,00€1mL*10mM (DMSO)62,00€Thiazovivin
CAS :Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.Formule :C15H13N5OSDegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :311.36Ref: TM-T2155
1mg35,00€2mg48,00€5mg67,00€10mg103,00€25mg190,00€50mg321,00€100mg469,00€1mL*10mM (DMSO)73,00€Y-27632
CAS :Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II.Formule :C14H21N3ODegré de pureté :99.53% - 99.87%Couleur et forme :SolidMasse moléculaire :247.34Belumosudil
CAS :Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).Formule :C26H24N6O2Degré de pureté :97.64% - 98.59%Couleur et forme :SolidMasse moléculaire :452.51Ref: TM-T6867
2mg48,00€5mg73,00€10mg90,00€25mg166,00€50mg250,00€100mg376,00€500mg895,00€1mL*10mM (DMSO)79,00€Y-27632 dihydrochloride
CAS :View and buy Y-27632 dihydrochloride from TargetMol.Y-27632 is a selective inhibitor of ROCKs.Cited in 10 publications.Formule :C14H21N3O·2HClDegré de pureté :97.96% - 99.98%Couleur et forme :SolidMasse moléculaire :320.26BDP5290
CAS :BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.)Formule :C17H18ClN7ODegré de pureté :97.22%Couleur et forme :SolidMasse moléculaire :371.82Ref: TM-T7301
1mg52,00€2mg77,00€5mg113,00€10mg178,00€25mg369,00€50mg535,00€100mg780,00€1mL*10mM (DMSO)124,00€Afuresertib
CAS :Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFormule :C18H17Cl2FN4OSDegré de pureté :97.51% - 99.51%Couleur et forme :SolidMasse moléculaire :427.32Ref: TM-T1911
1mg39,00€2mg50,00€5mg79,00€10mg97,00€25mg170,00€50mg274,00€100mg477,00€500mg1.035,00€1mL*10mM (DMSO)79,00€GSK269962A
CAS :GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.Formule :C29H30N8O5Degré de pureté :99.14% - 99.71%Couleur et forme :SolidMasse moléculaire :570.6GSK-25
CAS :GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K, and a dramatically improved P450 profile.Formule :C24H16Cl2F2N6ODegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :513.33Ref: TM-T4488
1mg47,00€2mg59,00€5mg92,00€10mg117,00€25mg172,00€50mg271,00€100mg454,00€1mL*10mM (DMSO)95,00€Netarsudil mesylate
CAS :Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.Formule :C30H35N3O9S2Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :645.74Ref: TM-T10358L2
1mg34,00€5mg66,00€10mg105,00€25mg236,00€50mg409,00€100mg700,00€1mL*10mM (DMSO)96,00€CAY10746
CAS :CAY10746 selectively inhibits ROCK I/II with IC50s: 0.014/0.003 μM, useful for diabetic retinopathy research.Formule :C26H23N3O5Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :457.48Ref: TM-T36196
2mg35,00€5mg57,00€10mg90,00€25mg182,00€50mg274,00€100mg434,00€200mg582,00€1mL*10mM (DMSO)57,00€H-1152
CAS :H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM).Formule :C16H21N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.42Y-33075
CAS :Y-33075 (Y-39983 free base) is a ROCK inhibitor that lowers IOP, increases blood flow to ONH, and increases the number of RGCs with regenerating axons.Formule :C16H16N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :280.32SB-772077B dihydrochloride
CAS :SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).Formule :C15H20Cl2N8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :415.28Rhodblock 6
CAS :Rhodblock 6 is a Rho kinase inhibitor, blocking phosphorylated MRLC localization by targeting ROCK activity.Formule :C12H13N3ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :215.25Rho-Kinase-IN-1
CAS :Rho-Kinase-IN-1: ROCK inhibitor, Ki of 30.5 nM (ROCK1) & 3.9 nM (ROCK2), used in research for diseases linked to cell overgrowth and inflammation.Formule :C20H24N4SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :352.5Ref: TM-T12721
1mg74,00€5mg145,00€10mg215,00€25mg378,00€50mg530,00€100mg702,00€200mg944,00€1mL*10mM (DMSO)111,00€CRT0066854 hydrochloride
CAS :CRT0066854 HCl inhibits atypical PKCs; IC50: PKCι 132 nM, PKCζ 639 nM, ROCK-II 620 nM.Formule :C24H27Cl2N5SDegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :488.48Ref: TM-T10888
1mg60,00€5mg129,00€10mg202,00€25mg341,00€50mg484,00€100mg677,00€200mg938,00€1mL*10mM (DMSO)155,00€CID-5056270
CAS :CID-5056270 has anticancer activity and can inhibit lung cancer, anal cancer, bladder cancer, cervical cancer, vulvar cancer, penile cancer, Burkitt's lymphoma
Formule :C17H13N3O3SDegré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :339.37AS 1892802
CAS :AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive effect similar to Tramadol, Diclofenac.Formule :C20H19N3O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :333.38Ref: TM-T22037
1mg49,00€5mg92,00€10mg166,00€25mg358,00€50mg530,00€100mg758,00€200mg1.044,00€1mL*10mM (DMSO)109,00€ROCK-IN-8
CAS :ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research,Formule :C30H25FN4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.61ROCK-IN-7
CAS :ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].Formule :C17H17N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :327.4ROCK-IN-9
CAS :ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 μM.
Formule :C20H20FN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :381.4ROCK2-IN-6 hydrochloride
CAS :ROCK2-IN-6 hydrochloride (Comp A)为一种选择性ROCK2抑制剂，适用于研究ROCK介导的疾病、自身免疫性病症与炎症。Formule :C26H22ClF2N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.95Chroman 1
CAS :Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 = 1 pM).Formule :C24H28N4O4Degré de pureté :99.67% - 99.84%Couleur et forme :SolidMasse moléculaire :436.5Ref: TM-T14960
1mg77,00€5mg169,00€10mg264,00€25mg454,00€50mg682,00€100mg938,00€1mL*10mM (DMSO)183,00€LX7101
CAS :LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).Formule :C23H29N7O3Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :451.52ROCK2-IN-2
CAS :ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).Formule :C18H12N6OSDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :360.39Ref: TM-T12747
1mg50,00€5mg111,00€10mg177,00€25mg304,00€50mg447,00€100mg692,00€200mg888,00€1mL*10mM (DMSO)136,00€ROCK-IN-1
CAS :ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurologicalFormule :C20H18FN3ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :335.37H-1152 dihydrochloride
CAS :H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.Formule :C16H23Cl2N3O2SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :392.34Ref: TM-T35328
1mg60,00€5mg135,00€10mg215,00€25mg415,00€50mg655,00€100mg888,00€1mL*10mM (DMSO)147,00€ROCK-IN-11
CAS :ROCK-IN-11 (example 94) is an effective inhibitor of ROCK1 and ROCK2, with an IC50 of ≤ 5 μM, and plays a significant role in cancer research.Formule :C22H20N4O4SCouleur et forme :SolidMasse moléculaire :436.484Rhodblock 1a
CAS :Rhodblock 1a is an inhibitor of the Rho kinase signaling pathway, which disrupts the localization and function of proteins within the Rho pathway. This interference hinders the proper formation of the cleavage furrow during cell division, leading to some cells either failing to form the cleavage furrow or forming a ruptured furrow, resulting in binucleated cells. Rhodblock 1a can be utilized for investigating cell division mechanisms and holds potential for research into cardiovascular diseases and cancer.
Formule :C20H16N2O2Couleur et forme :SolidMasse moléculaire :316.353Zelasudil
CAS :Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation.Formule :C22H21F2N7ODegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :437.445Ref: TM-T69665
1mg96,00€5mg172,00€10mg261,00€25mg444,00€50mg620,00€100mg865,00€1mL*10mM (DMSO)178,00€ROCK2-IN-6
CAS :ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment of ROCK-mediated, autoimmune, and inflammatory diseases [1].
Formule :C26H21F2N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.49ROCK-IN-6
CAS :ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1
Formule :C19H19N5O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.45
