Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2613 produits trouvés pour "Chromatine/Épigénétique"
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SRT 1720 dihydrochloride
CAS :SRT 1720 dihydrochloride is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).Formule :C25H25Cl2N7OSDegré de pureté :98.58%Couleur et forme :SolidMasse moléculaire :542.48Tucidinostat
CAS :Tucidinostat is an oral HDAC1/2/3/10 inhibitor (IC50: 67-160 nM), weaker on HDAC8/11, inactive on HDAC4/5/6/7/9.Formule :C22H19FN4O2Degré de pureté :97.01% - 99.95%Couleur et forme :SolidMasse moléculaire :390.41Ref: TM-T4481
5mg60,00€10mg95,00€25mg159,00€50mg250,00€100mg399,00€200mg558,00€500mg832,00€1mL*10mM (DMSO)60,00€TH34
CAS :TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.Formule :C15H16N2O2Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :256.3AZD5305
CAS :AZD5305 is a potent, selective and oral active PARP inhibitor.Formule :C22H26N6O2Degré de pureté :98.68% - 99.93%Couleur et forme :SolidMasse moléculaire :406.48Ref: TM-T9165
1mg107,00€5mg222,00€10mg358,00€25mg597,00€50mg850,00€100mg1.153,00€1mL*10mM (DMSO)245,00€Filgotinib
CAS :Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formule :C21H23N5O3SDegré de pureté :98.03% - ≥95%Couleur et forme :SolidMasse moléculaire :425.5OG-L002
CAS :OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.Formule :C15H15NODegré de pureté :97.05% - 98.62%Couleur et forme :SolidMasse moléculaire :225.29Danusertib
CAS :Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formule :C26H30N6O3Degré de pureté :97.88% - 98.79%Couleur et forme :White PowderMasse moléculaire :474.55(S)-CPI203
CAS :CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formule :C19H18ClN5OSDegré de pureté :99.01% - 99.92%Couleur et forme :SolidMasse moléculaire :399.9Ref: TM-T6026
2mg34,00€5mg55,00€10mg89,00€25mg170,00€50mg269,00€100mg424,00€200mg593,00€1mL*10mM (DMSO)58,00€MPT0G211 mesylate
CAS :MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.Formule :C18H19N3O5SCouleur et forme :SolidMasse moléculaire :389.43MM-102 TFA
CAS :MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 interaction, impeding H3K4 HMT activity.Formule :C37H50F5N7O6Degré de pureté :99.4% - 99.78%Couleur et forme :SolidMasse moléculaire :783.83Ref: TM-T8768
1mg37,00€2mg49,00€5mg100,00€10mg165,00€25mg269,00€50mg399,00€100mg587,00€1mL*10mM (DMSO)141,00€UNC 669
CAS :UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.Formule :C15H20BrN3ODegré de pureté :97.38%Couleur et forme :SolidMasse moléculaire :338.24G007-LK
CAS :G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.Formule :C25H16ClN7O3SDegré de pureté :97.63% - 98.17%Couleur et forme :SolidMasse moléculaire :529.96Ref: TM-T6842
1mg50,00€2mg66,00€5mg94,00€10mg158,00€25mg315,00€50mg502,00€100mg707,00€1mL*10mM (DMSO)116,00€γ-Oryzanol
CAS :γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in theFormule :C40H58O4Degré de pureté :mixture - mixtureCouleur et forme :White Or White Crystalline Powder OdourlessMasse moléculaire :602.9DR2313
CAS :DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.Formule :C8H10N2OSDegré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :182.24JQKD82
CAS :JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.Formule :C27H40N4O5Degré de pureté :100.00%Couleur et forme :SolidMasse moléculaire :500.63Pacritinib
CAS :Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formule :C28H32N4O3Degré de pureté :99.25% - 99.49%Couleur et forme :SolidMasse moléculaire :472.58CPI203
CAS :CPI203 (CPI 203) is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formule :C19H18ClN5OSDegré de pureté :99.13% - 99.77%Couleur et forme :SolidMasse moléculaire :399.9PHD-1-IN-1
CAS :PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).Formule :C13H8N4Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :220.23Ref: TM-T9627
1mg42,00€5mg92,00€10mg132,00€25mg231,00€50mg349,00€100mg522,00€200mg710,00€1mL*10mM (DMSO)90,00€RO8191
CAS :RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.Formule :C14H5F6N5ODegré de pureté :98% - 98.85%Couleur et forme :SolidMasse moléculaire :373.21Ref: TM-T22142
1mg43,00€2mg55,00€5mg93,00€10mg137,00€25mg254,00€50mg380,00€100mg573,00€500mg1.189,00€ZM-447439
CAS :ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formule :C29H31N5O4Degré de pureté :99.11% - 99.59%Couleur et forme :Pale Yellow SolidMasse moléculaire :513.59UPF 1069
CAS :UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.Formule :C17H13NO3Degré de pureté :98.80% - 99.88%Couleur et forme :SolidMasse moléculaire :279.29Pinometostat
CAS :Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor. Pinometostat has antitumor activity. Cost effective and quality assured.Formule :C30H42N8O3Degré de pureté :99.19% - 99.86%Couleur et forme :SolidMasse moléculaire :562.71Bisindolylmaleimide IV
CAS :Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)
Formule :C20H13N3O2Degré de pureté :98.83%Couleur et forme :Dark Red SolidMasse moléculaire :327.34AZ6102
CAS :AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.Formule :C25H28N6ODegré de pureté :97.98% - 99.91%Couleur et forme :SolidMasse moléculaire :428.53Molibresib
CAS :Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).Formule :C22H22ClN5O2Degré de pureté :97.70% - 99.08%Couleur et forme :SolidMasse moléculaire :423.9Ref: TM-T1906
1mg40,00€2mg54,00€5mg88,00€10mg118,00€25mg205,00€50mg339,00€100mg507,00€200mg712,00€500mg1.108,00€1mL*10mM (DMSO)87,00€(+)-JQ1 PA
CAS :(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).Formule :C22H20ClN5OSDegré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :437.95OAC1
CAS :OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.Formule :C14H11N3ODegré de pureté :99.49% - 99.65%Couleur et forme :SolidMasse moléculaire :237.26Ref: TM-T2040
1mg34,00€2mg47,00€5mg66,00€10mg92,00€25mg164,00€50mg299,00€100mg540,00€1mL*10mM (DMSO)66,00€COH-SR4
CAS :COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Formule :C13H8Cl4N2ODegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :350.03WZ4003
CAS :WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.Formule :C25H29ClN6O3Degré de pureté :99.65% - >99.99%Couleur et forme :SolidMasse moléculaire :496.99Ref: TM-T6291
5mg48,00€10mg73,00€25mg111,00€50mg166,00€100mg241,00€200mg358,00€500mg590,00€1mL*10mM (DMSO)50,00€GSK-LSD1 dihydrochloride
CAS :GSK-LSD1 dihydrochloride: potent LSD1 inhibitor, >1000x selective over MAO-A/B, LSD2, IC50: 16 nM.Formule :C14H22Cl2N2Degré de pureté :98.72% - >99.99%Couleur et forme :SolidMasse moléculaire :289.24Ref: TM-T2315
1mg38,00€2mg50,00€5mg67,00€10mg98,00€25mg198,00€50mg301,00€100mg495,00€500mg1.054,00€1mL*10mM (DMSO)67,00€Fraxinellone
CAS :1.Formule :C14H16O3Degré de pureté :99.35% - 99.92%Couleur et forme :SolidMasse moléculaire :232.27Ref: TM-T6S0071
2mg34,00€5mg50,00€10mg84,00€25mg152,00€50mg222,00€100mg334,00€200mg494,00€1mL*10mM (DMSO)81,00€HIF-2α-IN-4
CAS :HIF-2a translation inhibitor is a compound used as a molecular building block.Formule :C9H9N3O4S2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :287.32Ref: TM-T50099
5mg37,00€10mg60,00€25mg111,00€50mg200,00€100mg299,00€200mg430,00€1mL*10mM (DMSO)44,00€I-BRD9
CAS :I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.Formule :C22H22F3N3O3S2Degré de pureté :98.16% - 99.51%Couleur et forme :SolidMasse moléculaire :497.55Ref: TM-T6859
1mg38,00€2mg49,00€5mg71,00€10mg107,00€25mg205,00€50mg389,00€100mg577,00€1mL*10mM (DMSO)79,00€ABBV-744
CAS :ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.Formule :C28H30FN3O4Degré de pureté :97.03% - >99.99%Couleur et forme :SolidMasse moléculaire :491.55Ref: TM-T4697
1mg44,00€2mg56,00€5mg90,00€10mg142,00€25mg284,00€50mg409,00€100mg500,00€200mg718,00€1mL*10mM (DMSO)90,00€Piribedil
CAS :Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formule :C16H18N4O2Degré de pureté :99.79% - 99.82%Couleur et forme :SolidMasse moléculaire :298.34Deoxyshikonin
CAS :1.Formule :C16H16O4Degré de pureté :99.36% - ≥95%Couleur et forme :SolidMasse moléculaire :272.3MRTX-1719
CAS :MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.Formule :C23H18ClFN6O2Degré de pureté :98.27% - 99.18%Couleur et forme :SolidMasse moléculaire :464.88Pim1/AKK1-IN-1
CAS :Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.Formule :C20H13N5ODegré de pureté :97.03% - 98.69%Couleur et forme :SolidMasse moléculaire :339.35Ref: TM-T5093
1mg85,00€2mg124,00€5mg173,00€10mg263,00€25mg464,00€50mg672,00€100mg945,00€1mL*10mM (DMSO)192,00€dBET6
CAS :dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.Formule :C42H45ClN8O7SDegré de pureté :97.57% - 99.12%Couleur et forme :SolidMasse moléculaire :841.37Ref: TM-T5130
1mg50,00€5mg92,00€10mg160,00€25mg290,00€50mg467,00€100mg675,00€200mg850,00€500mg1.243,00€1mL*10mM (DMSO)148,00€SGC-SMARCA-BRDVIII
CAS :SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM,Formule :C19H25N5O3Degré de pureté :99.54% - 99.92%Couleur et forme :SolidMasse moléculaire :371.43Ref: TM-T9568
1mg44,00€5mg66,00€10mg101,00€25mg222,00€50mg356,00€100mg530,00€500mg1.153,00€1mL*10mM (DMSO)54,00€5-AIQ
CAS :5-aminoisoquinolin-1(2H)-one is the inhibitor of calf thymus PARP1.Formule :C9H8N2ODegré de pureté :95.95%Couleur et forme :SolidMasse moléculaire :160.17BRD4770
CAS :BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.Formule :C25H23N3O3Degré de pureté :99.53% - 99.82%Couleur et forme :SolidMasse moléculaire :413.47Hispidulin
CAS :Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).Formule :C16H12O6Degré de pureté :98.53% - 99.87%Couleur et forme :SolidMasse moléculaire :300.26KC7F2
CAS :KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.Formule :C16H16Cl4N2O4S4Degré de pureté :98% - 99.11%Couleur et forme :SolidMasse moléculaire :570.38RK-287107
CAS :RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).Formule :C22H26F2N4O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :416.46MI-463
CAS :MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).Formule :C24H23F3N6SDegré de pureté :99.18% - >99.99%Couleur et forme :SolidMasse moléculaire :484.54Bempedoic acid
CAS :Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Formule :C19H36O5Degré de pureté :99.85% - 99.94%Couleur et forme :SolidMasse moléculaire :344.49Ref: TM-T3625
2mg34,00€5mg50,00€10mg70,00€25mg118,00€50mg207,00€100mg333,00€500mg797,00€1mL*10mM (DMSO)52,00€Ilorasertib
CAS :Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formule :C25H21FN6O2SDegré de pureté :96.17% - 97.49%Couleur et forme :SolidMasse moléculaire :488.54PF-CBP1 hydrochloride
CAS :PF-CBP1 HCl selectively inhibits CREBBP bromodomain (IC50: 125 nM) and p300 (IC50: 363 nM).Formule :C29H37ClN4O3Degré de pureté :97.11% - 99.02%Couleur et forme :SolidMasse moléculaire :525.08Atractylenolide I
CAS :Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formule :C15H18O2Degré de pureté :97.55% - 99.92%Couleur et forme :SolidMasse moléculaire :230.30EED226
CAS :EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.Formule :C17H15N5O3SDegré de pureté :98.14% - 99.33%Couleur et forme :SolidMasse moléculaire :369.4Iniparib
CAS :Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).Formule :C7H5IN2O3Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :292.03Ref: TM-T6224
5mg52,00€10mg73,00€25mg119,00€50mg216,00€100mg340,00€200mg540,00€500mg863,00€1mL*10mM (DMSO)52,00€GLPG0634 analog
CAS :GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.Formule :C23H18N6O2Degré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :410.43Ref: TM-T3076
1mg38,00€2mg50,00€5mg84,00€10mg137,00€25mg250,00€50mg442,00€100mg623,00€500mg1.305,00€1mL*10mM (DMSO)93,00€NVP-TNKS656
CAS :NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.Formule :C27H34N4O5Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :494.58Ref: TM-T3261
1mg43,00€2mg54,00€5mg84,00€10mg122,00€25mg248,00€50mg421,00€100mg617,00€1mL*10mM (DMSO)93,00€RBN012759
CAS :RBN012759 inhibits PARP14 protein and is more than 300-fold selective over all PARP family members.Cost-effective and quality-assured.Formule :C19H23FN2O3SDegré de pureté :98.87% - 99.96%Couleur et forme :SolidMasse moléculaire :378.46Ref: TM-T22414
1mg104,00€2mgÀ demander5mg250,00€10mg373,00€25mg645,00€50mg938,00€100mg1.311,00€200mg1.768,00€1mL*10mM (DMSO)274,00€MLN8054
CAS :MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formule :C25H15ClF2N4O2Degré de pureté :98.07% - 98.26%Couleur et forme :SolidMasse moléculaire :476.86Ref: TM-T6315
1mg50,00€2mg67,00€5mg84,00€10mg120,00€25mg220,00€50mg356,00€100mg537,00€1mL*10mM (DMSO)88,00€1,2-Dipalmitoyl-sn-glycerol
CAS :1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.Formule :C35H68O5Degré de pureté :97.84% - 99.78%Couleur et forme :SolidMasse moléculaire :568.91Ruboxistaurin mesylate
CAS :Ruboxistaurin: PKC beta inhibitor, eases oxidative stress, heart issues & nephropathy in diabetic rats, halts retinal neovascularization.Formule :C29H32N4O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :564.65AZ505
CAS :AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).Formule :C29H38Cl2N4O4Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :577.54Ref: TM-TQ0100
1mg60,00€5mg130,00€10mg178,00€25mg295,00€50mg462,00€100mg623,00€1mL*10mM (DMSO)165,00€MR837
CAS :MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.Formule :C16H14N2OSDegré de pureté :99.77% - 99.85%Couleur et forme :SolidMasse moléculaire :282.36Ref: TM-T8879
2mg38,00€5mg55,00€10mg92,00€25mg138,00€50mg243,00€100mg355,00€200mg502,00€1mL*10mM (DMSO)66,00€MK-8617
CAS :MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).Formule :C24H21N5O4Degré de pureté :99.38% - >99.99%Couleur et forme :SolidMasse moléculaire :443.45Bromosporine
CAS :Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.Formule :C17H20N6O4SDegré de pureté :99.65% - 99.79%Couleur et forme :SolidMasse moléculaire :404.44Ref: TM-T6255
1mg44,00€2mg57,00€5mg93,00€10mg133,00€25mg260,00€50mg416,00€100mg665,00€200mg888,00€1mL*10mM (DMSO)92,00€SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).Formule :C25H20FN7ODegré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :453.47Ref: TM-T8685
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)177,00€8-CHLOROQUINAZOLIN-4(1H)-ONE
CAS :8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)Formule :C8H5ClN2ODegré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :180.59(R)-(-)-JQ1 Enantiomer
CAS :(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)
Formule :C23H25ClN4O2SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :456.99ICG001
CAS :ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.Formule :C33H32N4O4Degré de pureté :99.06% - 99.95%Couleur et forme :SolidMasse moléculaire :548.63Ref: TM-T2237
1mg34,00€5mg66,00€10mg101,00€25mg197,00€50mg341,00€100mg530,00€500mg1.134,00€1mL*10mM (DMSO)81,00€Rucaparib hydrochloride
CAS :Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.Formule :C19H19ClFN3OCouleur et forme :SolidMasse moléculaire :359.83GSK1379725A
CAS :GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).
Formule :C23H23FN6O3Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :450.47DMOG
CAS :DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.Formule :C6H9NO5Degré de pureté :80.23% - 99.98%Couleur et forme :SolidMasse moléculaire :175.14Bobcat339
CAS :Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.Formule :C16H12ClN3ODegré de pureté :97.79% - 98.76%Couleur et forme :SolidMasse moléculaire :297.74Rucaparib acetate
CAS :Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.Formule :C21H22FN3O3Couleur et forme :SolidMasse moléculaire :383.423JQEZ5
CAS :JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).Formule :C30H38N8O2Degré de pureté :98.14% - ≥98%Couleur et forme :SolidMasse moléculaire :542.68Protein kinase inhibitor 6
CAS :Protein kinase inhibitor 6 is a protein kinase inhibitor.Formule :C13H9FN2SDegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :244.29Ref: TM-T9779
2mg34,00€5mg52,00€10mg86,00€25mg163,00€50mg222,00€100mg324,00€200mg440,00€1mL*10mM (DMSO)52,00€MOTS-c(Human) Acetate(1627580-64-6 free)
MOTS-c(Human) Acetate is a mitochondrial-derived peptide.Formule :C103H156N28O24S2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :2234.64EB-47 dihydrochloride
CAS :EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).Formule :C24H29Cl2N9O6Couleur et forme :SolidMasse moléculaire :610.45PIN1 inhibitor API-1
CAS :API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.Formule :C15H13F3N6O2Degré de pureté :98.48%Couleur et forme :SolidMasse moléculaire :366.3Ref: TM-T16538
1mg57,00€5mg120,00€10mg222,00€25mg326,00€50mg485,00€100mg612,00€200mg850,00€500mg1.243,00€1mL*10mM (DMSO)133,00€Amodiaquine
CAS :Amodiaquine is a synthetic aminoquinoline, used to treat malaria.Formule :C20H22ClN3ODegré de pureté :99.78% - 99.99%Couleur et forme :Crystals From Absolute Ethanol SolidMasse moléculaire :355.86Ref: TM-T8381
1mg49,00€2mg66,00€5mg90,00€10mg170,00€25mg281,00€50mg394,00€100mg550,00€1mL*10mM (DMSO)105,00€XMD8-92
CAS :XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).Formule :C26H30N6O3Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :474.55Ruboxistaurin
CAS :Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.Formule :C28H28N4O3Couleur et forme :SolidMasse moléculaire :468.55YKL-06-061
CAS :YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.Formule :C30H37N7O2Degré de pureté :99.52% - 99.79%Couleur et forme :SolidMasse moléculaire :527.66MS31 trihydrochloride
MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.Formule :C20H30Cl3N3O2Couleur et forme :SolidMasse moléculaire :450.83SC-43
CAS :SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).Formule :C21H13ClF3N3O2Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :431.85-Ph-IAA
CAS :5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.
Formule :C16H13NO2Degré de pureté :99.37% - 99.973%Couleur et forme :SolidMasse moléculaire :251.28Ethyl 3,4-dihydroxybenzoate
CAS :Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formule :C9H10O4Degré de pureté :99.88%Couleur et forme :White Crystal Or PowderMasse moléculaire :182.17Birabresib
CAS :Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4Formule :C25H22ClN5O2SDegré de pureté :98.3% - 99.36%Couleur et forme :SolidMasse moléculaire :491.99Ref: TM-T6032
2mg46,00€5mg70,00€10mg90,00€25mg142,00€50mg222,00€100mg375,00€200mg560,00€500mg893,00€1mL*10mM (DMSO)74,00€(+)-JQ-1
CAS :(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formule :C23H25ClN4O2SDegré de pureté :97.57% - 99.97%Couleur et forme :SolidMasse moléculaire :456.99Ref: TM-T2110
1mg34,00€2mg42,00€5mg57,00€10mg74,00€25mg90,00€50mg137,00€100mg178,00€200mg268,00€500mg485,00€1mL*10mM (DMSO)63,00€AZD-2461
CAS :AZD2461 is a novel PARP inhibitor.Formule :C22H22FN3O3Degré de pureté :98% - 99.87%Couleur et forme :SolidMasse moléculaire :395.43Menin-MLL inhibitor 20
CAS :Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.Formule :C33H40N8O4Degré de pureté :97.77%Couleur et forme :SolidMasse moléculaire :612.72Ref: TM-T9399
1mg38,00€5mg86,00€10mg128,00€25mg250,00€50mg369,00€100mg527,00€200mg712,00€1mL*10mM (DMSO)95,00€Abrocitinib
CAS :Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).Formule :C14H21N5O2SDegré de pureté :99.09% - 99.91%Couleur et forme :SolidMasse moléculaire :323.41Isoxazole
CAS :Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.Formule :C3H3NODegré de pureté :98% - 99.34%Couleur et forme :Colorless LiquidMasse moléculaire :69.06Daphnetin
CAS :Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Formule :C9H6O4Degré de pureté :97.47% - 99.8%Couleur et forme :SolidMasse moléculaire :178.14UMB298
CAS :UMB298 is a potent and selective CBP/P300 bromodomain inhibitor. UMB298 inhibits BRD4 with IC50 of 5193nM.Formule :C27H31ClN4O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :479.01Ref: TM-T9194
1mg46,00€5mg94,00€10mg149,00€25mg250,00€50mg351,00€100mg480,00€200mg622,00€1mL*10mM (DMSO)99,00€3-methyl-1,2,3,4-tetrahydroquinazolin-2-one
CAS :3-methyl-1,2,3,4-tetrahydroquinazolin-2-one is a inhibitor of BRD4 .Formule :C9H10N2ODegré de pureté :99.3% - 99.64%Couleur et forme :SolidMasse moléculaire :162.19Ref: TM-T50006
2mg37,00€5mg52,00€10mg78,00€25mg119,00€50mg172,00€100mg259,00€500mg642,00€1mL*10mM (DMSO)56,00€Alobresib
CAS :Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.Formule :C26H23N5O2Degré de pureté :97.63%Couleur et forme :SolidMasse moléculaire :437.49Ref: TM-T8495
1mg70,00€2mg87,00€5mg137,00€10mg260,00€25mg507,00€50mg713,00€100mg982,00€1mL*10mM (DMSO)150,00€PKC-iota inhibitor 1
CAS :PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formule :C21H22N6ODegré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :374.44Ref: TM-T8764
1mg107,00€2mg152,00€5mg219,00€10mg349,00€25mg583,00€50mg833,00€100mg1.134,00€500mg2.268,00€1mL*10mM (DMSO)226,00€Tubacin
CAS :Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.Formule :C41H43N3O7SDegré de pureté :97.62% - 98.75%Couleur et forme :SolidMasse moléculaire :721.86MT-DADMe-ImmA
CAS :MT-DADMe-ImmA (MTDIA) is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).Formule :C13H19N5OSDegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :293.39Ref: TM-TQ0008
1mg70,00€5mg135,00€10mg225,00€25mg399,00€50mg560,00€100mg787,00€200mg1.035,00€1mL*10mM (DMSO)169,00€Reversine
CAS :Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Formule :C21H27N7ODegré de pureté :98% - 99.45%Couleur et forme :SolidMasse moléculaire :393.49Ref: TM-T1825
1mg35,00€2mg50,00€5mg66,00€10mg84,00€25mg156,00€50mg212,00€100mg371,00€1mL*10mM (DMSO)66,00€J-147
CAS :J-147, a curcumin derivative, is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.Formule :C18H17F3N2O2Degré de pureté :99.61% - >99.99%Couleur et forme :SolidMasse moléculaire :350.33N-Oxalylglycine
CAS :N-Oxalylglycine (Oxalylglycine) is a cell permeable inhibitor of α-ketoglutarate-dependent enzymes.Formule :C4H5NO5Degré de pureté :99.23%Couleur et forme :Colourless SolidMasse moléculaire :147.09
