Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2613 produits trouvés pour "Chromatine/Épigénétique"
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AK-1
CAS :AK-1: SIRT2 inhibitor, IC50 12.5 μM, hinders Alzheimer's neurodegeneration, arrests colon cancer cell cycle.Formule :C19H21N3O5SDegré de pureté :98.32% - 99.44%Couleur et forme :SolidMasse moléculaire :403.45SHR0302
CAS :SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3,Formule :C18H22N8O2SDegré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :414.48Ref: TM-T9195
1mg80,00€5mg183,00€10mg298,00€25mg512,00€50mg817,00€100mg1.311,00€1mL*10mM (DMSO)167,00€Nudifloramide
CAS :Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).Formule :C7H8N2O2Degré de pureté :99.7% - ≥95%Couleur et forme :SolidMasse moléculaire :152.15Rucaparib Phosphate
CAS :Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.Formule :C19H18FN3O·H3PO4Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :421.36Ref: TM-T6127
1mg35,00€2mg50,00€5mg74,00€10mg109,00€25mg178,00€50mg235,00€100mg371,00€200mg553,00€1mL*10mM (DMSO)74,00€Cerdulatinib
CAS :Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formule :C20H27N7O3SDegré de pureté :98.74% - 99.49%Couleur et forme :SolidMasse moléculaire :445.54Ref: TM-T2487
1mg42,00€2mg52,00€5mg74,00€10mg101,00€25mg175,00€50mg268,00€100mg409,00€200mg573,00€500mg888,00€1mL*10mM (DMSO)81,00€ORY1001
CAS :ORY1001: Oral LSD1/KDM1A inhibitor, highly selective, IC50 <20 nM.Formule :C15H22N2·2HClDegré de pureté :99.85% - 99.96%Couleur et forme :SolidMasse moléculaire :303.27Ref: TM-T6922
1mg56,00€2mg79,00€5mg127,00€10mg221,00€25mg427,00€50mg625,00€100mg889,00€500mg1.783,00€1mL*10mM (DMSO)127,00€Citarinostat
CAS :ACY-241 (Citarinostat), a potent oral HDAC inhibitor, may induce tumor cell death and block growth by altering gene expression.Formule :C24H26ClN5O3Degré de pureté :98.06% - 99.06%Couleur et forme :SolidMasse moléculaire :467.95Ruxolitinib (S enantiomer)
CAS :Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.Formule :C17H18N6Degré de pureté :99.37% - 99.79%Couleur et forme :SolidMasse moléculaire :306.36M344
CAS :M344 (Histone Deacetylase Inhibitor III) is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.Formule :C16H25N3O3Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :307.39Bobcat339
CAS :Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.Formule :C16H12ClN3ODegré de pureté :97.79% - 98.76%Couleur et forme :SolidMasse moléculaire :297.74CYC-116
CAS :CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormule :C18H20N6OSDegré de pureté :97.36% - 97.59%Couleur et forme :SolidMasse moléculaire :368.46Thiomyristoyl
CAS :Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.Formule :C34H51N3O3SDegré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :581.85Ref: TM-T3447
1mg54,00€2mg73,00€5mg92,00€10mg117,00€25mg215,00€50mg360,00€100mg537,00€1mL*10mM (DMSO)117,00€Momelotinib HCl
CAS :Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.Formule :C23H24Cl2N6O2Couleur et forme :SolidMasse moléculaire :487.38Tucidinostat
CAS :Tucidinostat is an oral HDAC1/2/3/10 inhibitor (IC50: 67-160 nM), weaker on HDAC8/11, inactive on HDAC4/5/6/7/9.Formule :C22H19FN4O2Degré de pureté :97.01% - 99.95%Couleur et forme :SolidMasse moléculaire :390.41Ref: TM-T4481
5mg60,00€10mg95,00€25mg159,00€50mg250,00€100mg399,00€200mg558,00€500mg832,00€1mL*10mM (DMSO)60,00€A1874
CAS :A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in inhibiting many cancer cell lines proliferation.
Formule :C58H62Cl3F2N9O7SDegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :1173.59JNJ-7706621
CAS :JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formule :C15H12F2N6O3SDegré de pureté :99.1% - 99.85%Couleur et forme :SolidMasse moléculaire :394.36Ref: TM-T6126
1mg48,00€5mg100,00€10mg155,00€25mg268,00€50mg432,00€100mg595,00€200mg833,00€1mL*10mM (DMSO)94,00€Apabetalone
CAS :Apabetalone (RVX000222) , an effective BET bromodomain inhibitor, has been investigated for the treatment of diabetes, atherosclerosis, and coronary arteryFormule :C20H22N2O5Degré de pureté :98.08% - ≥98%Couleur et forme :SolidMasse moléculaire :370.4LMK-235
CAS :LMK-235 is a potent HDAC inhibitor, and is used in cancer research.Formule :C15H22N2O4Degré de pureté :98.18% - 99.68%Couleur et forme :SolidMasse moléculaire :294.35Ref: TM-T6061
5mg52,00€10mg74,00€25mg132,00€50mg222,00€100mg403,00€200mg593,00€500mg888,00€1mL*10mM (DMSO)49,00€653-47 hydrochloride
CAS :653-47 hydrochloride boosts CREB inhibition by 666-15 and weakly inhibits CREB itself (IC50: 26.3 μM).Formule :C20H20Cl2N2O3Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :407.29Ref: TM-T8890
1mg87,00€5mg177,00€10mg334,00€25mg567,00€50mg807,00€100mg1.099,00€500mg2.205,00€1mL*10mM (DMSO)203,00€PKC-θ inhibitor hcl
CAS :PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).Formule :C20H26ClF3N6O3Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :490.91Ref: TM-T5817
1mg88,00€2mg114,00€5mg220,00€10mg356,00€25mg595,00€50mg848,00€100mg1.153,00€500mg2.305,00€SIS17
CAS :SIS17: Potent, selective HDAC11 inhibitor (IC50: 0.83 μM), blocks serine hydroxymethyl transferase 2 demyristoylation, spares other HDACs.Formule :C21H38N2OSDegré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :366.6Darovasertib
CAS :Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).Formule :C22H23F3N8ODegré de pureté :98.72% - ≥95%Couleur et forme :SolidMasse moléculaire :472.47GSK199
CAS :GSK199 is a selective PAD4 inhibitor(IC50 of 200 nM in the absence of calcium).Formule :C24H29ClN6O2Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :468.98Ref: TM-T8861
1mg62,00€5mg133,00€10mg215,00€25mg351,00€50mg494,00€100mg665,00€200mg893,00€1mL*10mM (DMSO)156,00€Remetinostat
CAS :Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cellFormule :C16H21NO6Degré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :323.34CBP/EP300-IN-1
CAS :CBP/EP300-IN-1 is a CBP/EP300 bromodomain inhibitor.Formule :C23H23FN2O5Degré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :426.44Ref: TM-T7264
1mg46,00€2mg62,00€5mg92,00€10mg152,00€25mg250,00€50mg353,00€100mg502,00€200mg682,00€1mL*10mM (DMSO)100,00€Nicotinamide riboside chloride
CAS :NR, also SRT647, is a B3 vitamin form; precursor to NAD+.Formule :C11H15ClN2O5Degré de pureté :98.92% - 99.86%Couleur et forme :SolidMasse moléculaire :290.7Iso-H7 dihydrochloride
CAS :Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.Formule :C14H19Cl2N3O2SDegré de pureté :99.53%Couleur et forme :White Crystalline SolidMasse moléculaire :364.29Ruxolitinib phosphate
CAS :Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formule :C17H21N6O4PDegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :404.36Ref: TM-T3043
1g583,00€5mg49,00€10mg62,00€25mg78,00€50mg92,00€100mg138,00€200mg215,00€500mg395,00€1mL*10mM (DMSO)56,00€EX229
CAS :EX229 (C991) is an allosteric activator of AMPK, with Kds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1, and α1β2γ1, respectively.Formule :C24H18ClN3O3Degré de pureté :99.20% - 99.36%Couleur et forme :SolidMasse moléculaire :431.87Ref: TM-TQ0028
1mg34,00€2mg49,00€5mg71,00€10mg105,00€25mg210,00€50mg356,00€100mg535,00€1mL*10mM (DMSO)80,00€6-Thioguanine
CAS :6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formule :C5H5N5SDegré de pureté :98.75% - >99.99%Couleur et forme :Odorless Or Almost Odorless Pale Yellow Crystalline PowderMasse moléculaire :167.19Tozasertib
CAS :Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formule :C23H28N8OSDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :464.59GSK620
CAS :GSK620, a selective pan-BD2 inhibitor, has anti-inflammatory properties and favorable oral pharmacokinetics.Formule :C18H19N3O3Degré de pureté :99.42% - 99.88%Couleur et forme :SolidMasse moléculaire :325.36Ref: TM-T9020
2mg34,00€5mg49,00€10mg73,00€25mg136,00€50mg212,00€100mg314,00€200mg467,00€1mL*10mM (DMSO)87,00€WH-4-025
CAS :WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.Formule :C39H38F3N7O5Degré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :741.76Ref: TM-T9219
1mg38,00€2mg50,00€5mg84,00€10mg130,00€25mg250,00€50mg396,00€100mg585,00€1mL*10mM (DMSO)93,00€Pamiparib
CAS :Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.Formule :C16H15FN4ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :298.31MS37452
CAS :MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).Formule :C22H26N2O5Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :398.45Ref: TM-T21767
5mg49,00€10mg84,00€25mg166,00€50mg289,00€100mg500,00€500mg1.063,00€1mL*10mM (DMSO)54,00€EPZ005687
CAS :EPZ005687 is a potent and selective inhibitor of EZH2.Formule :C32H37N5O3Degré de pureté :97.06% - 99.64%Couleur et forme :SolidMasse moléculaire :539.67MC1568
CAS :MC1568 is a specific HDAC inhibitor for maize HD1-A (IC50: 100 nM, in a cell-free assay). It is 34-fold more selective for HD1-A than HD1-B.Formule :C17H15FN2O3Degré de pureté :89.82% - ≥95%Couleur et forme :SolidMasse moléculaire :314.31Fluzoparib
CAS :Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.Formule :C22H16F4N6O2Degré de pureté :98.53% - 99.63%Couleur et forme :SolidMasse moléculaire :472.4Ref: TM-T8806
1mg60,00€2mg88,00€5mg124,00€10mg197,00€25mg389,00€50mg565,00€100mg822,00€500mg1.681,00€1mL*10mM (DMSO)145,00€HDAC8-IN-1
CAS :MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines.Formule :C22H19NO3Degré de pureté :97.13% - 99.19%Couleur et forme :SolidMasse moléculaire :345.39Ref: TM-T7082
1mg34,00€5mg63,00€10mg95,00€25mg172,00€50mg259,00€100mg330,00€200mg467,00€1mL*10mM (DMSO)70,00€YF-2
CAS :YF-2 activates histone acetyltransferases (H3, CBP, PCAF, GCN5) across the blood-brain barrier; EC50s: 2.75-49.31 μM.Formule :C20H22ClF3N2O3Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :430.85BCI-121
CAS :BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.Formule :C14H18BrN3O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :340.22Baricitinib
CAS :Baricitinib (INCB028050) is an orally JAK1 and JAK2 inhibitor. Baricitinib has anti-inflammatory and anti-tumor activity. Cost-effective and quality-assured.Formule :C16H17N7O2SDegré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :371.42Ref: TM-T2485
5mg48,00€10mg70,00€25mg95,00€50mg109,00€100mg137,00€200mg178,00€500mg295,00€1mL*10mM (DMSO)65,00€Tofacitinib Citrate
CAS :Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).Formule :C22H28N6O8Degré de pureté :99.19% - 99.75%Couleur et forme :SolidMasse moléculaire :504.49SGC2085 HCl
CAS :SGC2085: potent, selective CARM1 inhibitor; IC50=50 nM; >100x selectivity vs other PRMTs; impacts cancer growth.Formule :C19H24N2O2·HClDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :348.87Ref: TM-T4013
1mg93,00€2mg150,00€5mg190,00€10mg343,00€25mg567,00€50mg825,00€100mg1.130,00€1mL*10mM (DMSO)244,00€GSK-J1
CAS :GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.Formule :C22H23N5O2Degré de pureté :99.23% - 99.67%Couleur et forme :SolidMasse moléculaire :389.45CP21R7
CAS :CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Formule :C19H15N3O2Degré de pureté :96.14% - 99.16%Couleur et forme :SolidMasse moléculaire :317.34Ref: TM-T3684
1mg38,00€2mg50,00€5mg84,00€10mg120,00€25mg236,00€50mg356,00€100mg537,00€1mL*10mM (DMSO)77,00€DDP-38003 trihydrochloride
DDP-38003 trihydrochloride is a novel, orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor with an IC50 of 84 nM.Formule :C21H29Cl3N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.84INCB-057643
CAS :INCB057643 is a potent, selective and orally bioavailable BET inhibitor.Formule :C20H21N3O5SDegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :415.46Ref: TM-T5417
1mg39,00€5mg86,00€10mg133,00€25mg231,00€50mg349,00€100mg475,00€200mg652,00€1mL*10mM (DMSO)95,00€WIKI4
CAS :WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).Formule :C29H23N5O3SDegré de pureté :99.6% - 99.71%Couleur et forme :SolidMasse moléculaire :521.59Palmatine
CAS :Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.Formule :C21H22NO4Degré de pureté :96.28% - 99.49%Couleur et forme :SolidMasse moléculaire :352.4BYK204165
CAS :BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)Formule :C15H12N2O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :252.27Ref: TM-T7896
1mg44,00€5mg66,00€10mg90,00€25mg167,00€50mg236,00€100mg349,00€200mg512,00€1mL*10mM (DMSO)73,00€PJ34 hydrochloride
CAS :PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.Formule :C17H18ClN3O2Degré de pureté :98.87% - ≥95%Couleur et forme :SolidMasse moléculaire :331.8Palmatine chloride
CAS :Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Formule :C21H22ClNO4Degré de pureté :97.9% - 99.47%Couleur et forme :SolidMasse moléculaire :387.86Fedratinib
CAS :Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Formule :C27H36N6O3SDegré de pureté :97.31% - 99.96%Couleur et forme :SolidMasse moléculaire :524.68Ref: TM-T1995
1g592,00€5mg50,00€10mg65,00€50mg107,00€100mg127,00€200mg205,00€500mg447,00€1mL*10mM (DMSO)54,00€BI 2536
CAS :BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.Formule :C28H39N7O3Degré de pureté :98% - 99.88%Couleur et forme :SolidMasse moléculaire :521.65Ref: TM-T6173
1mg43,00€2mg56,00€5mg93,00€10mg98,00€25mg117,00€50mg187,00€100mg333,00€500mg797,00€1mL*10mM (DMSO)92,00€5,7-Dihydroxychromone
CAS :1.Formule :C9H6O4Degré de pureté :99.76% - ≥95%Couleur et forme :SolidMasse moléculaire :178.14Ref: TM-T5S1805
1mg44,00€5mg84,00€10mg119,00€25mg197,00€50mg294,00€100mg437,00€500mg954,00€1mL*10mM (DMSO)75,00€UPF 1069
CAS :UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.Formule :C17H13NO3Degré de pureté :98.80% - 99.88%Couleur et forme :SolidMasse moléculaire :279.29Gandotinib
CAS :LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formule :C23H25ClFN7ODegré de pureté :99.33% - 99.86%Couleur et forme :SolidMasse moléculaire :469.94TP-064
CAS :TP-064: Potent, selective PRMT4 inhibitor, IC50 < 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation at 43nM.Formule :C28H34N4O2Degré de pureté :97.85%Couleur et forme :SolidMasse moléculaire :458.6Ref: TM-T28996
1mg35,00€2mg50,00€5mg74,00€10mg113,00€25mg231,00€50mg462,00€100mg673,00€1mL*10mM (DMSO)75,00€FLLL32
CAS :FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).Formule :C28H32O6Degré de pureté :97% - 97.90%Couleur et forme :SolidMasse moléculaire :464.55Ref: TM-T6838
2mg43,00€5mg63,00€10mg88,00€25mg117,00€50mg187,00€100mg333,00€500mg797,00€1mL*10mM (DMSO)69,00€HJ-PI01
CAS :HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.Formule :C14H11NO2Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :225.24Ref: TM-T9583
1mg34,00€5mg75,00€10mg110,00€25mg245,00€50mg363,00€100mg515,00€200mg700,00€1mL*10mM (DMSO)73,00€GDC-0214
CAS :GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formule :C28H28ClF2N9O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :612.03Ref: TM-T9826
1mg93,00€5mg182,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.099,00€1mL*10mM (DMSO)245,00€BRD4770
CAS :BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.Formule :C25H23N3O3Degré de pureté :99.53% - 99.82%Couleur et forme :SolidMasse moléculaire :413.47G5-7
CAS :G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formule :C22H19F2NO3Degré de pureté :97.3%Couleur et forme :SolidMasse moléculaire :383.39Ref: TM-T8742
1mg35,00€5mg71,00€10mg96,00€25mg172,00€50mg248,00€100mg348,00€200mg470,00€1mL*10mM (DMSO)78,00€GSK484 hydrochloride
CAS :GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.Formule :C27H32ClN5O3Degré de pureté :98.32% - 99.62%Couleur et forme :SolidMasse moléculaire :510.03Ref: TM-TQ0067
1mg67,00€5mg140,00€10mg205,00€25mg413,00€50mg590,00€100mg840,00€1mL*10mM (DMSO)156,00€VX-11e
CAS :VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.Formule :C24H20Cl2FN5O2Degré de pureté :98.92% - ≥98%Couleur et forme :SolidMasse moléculaire :500.35Decernotinib
CAS :Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.Formule :C18H19F3N6ODegré de pureté :99.28% - >99.99%Couleur et forme :SolidMasse moléculaire :392.38Ref: TM-T2636
1mg34,00€2mg48,00€5mg71,00€10mg99,00€25mg197,00€50mg295,00€100mg447,00€1mL*10mM (DMSO)79,00€(E/Z)-Zotiraciclib
CAS :(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formule :C23H24N4ODegré de pureté :97.75% - 99.92%Couleur et forme :SolidMasse moléculaire :372.46Ref: TM-T21503
1mg43,00€2mg56,00€5mg93,00€10mg113,00€25mg200,00€50mg330,00€100mg480,00€1mL*10mM (DMSO)90,00€PFI-1
CAS :PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Formule :C16H17N3O4SDegré de pureté :98.74% - 99.19%Couleur et forme :SolidMasse moléculaire :347.393-deazaneplanocin A HCl
CAS :3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog 2(EZH2) inhibitor.Formule :C12H15ClN4O3Degré de pureté :93.24% - 98.9%Couleur et forme :SolidMasse moléculaire :298.73WZ4003
CAS :WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.Formule :C25H29ClN6O3Degré de pureté :99.65% - >99.99%Couleur et forme :SolidMasse moléculaire :496.99Ref: TM-T6291
5mg48,00€10mg73,00€25mg111,00€50mg166,00€100mg241,00€200mg358,00€500mg590,00€1mL*10mM (DMSO)50,00€ABBV-744
CAS :ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.Formule :C28H30FN3O4Degré de pureté :97.03% - >99.99%Couleur et forme :SolidMasse moléculaire :491.55Ref: TM-T4697
1mg44,00€2mg56,00€5mg90,00€10mg142,00€25mg284,00€50mg409,00€100mg500,00€200mg718,00€1mL*10mM (DMSO)90,00€BRD9539
CAS :BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μMFormule :C24H21N3O3Degré de pureté :98% - 99.57%Couleur et forme :SolidMasse moléculaire :399.44JNJ-42041935
CAS :JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.Formule :C12H6ClF3N4O3Degré de pureté :99.58% - ≥95%Couleur et forme :SolidMasse moléculaire :346.65Ref: TM-T3180
1mg40,00€2mg52,00€5mg88,00€10mg119,00€25mg210,00€50mg354,00€100mg567,00€500mg1.198,00€1mL*10mM (DMSO)87,00€Succinic acid sodium
CAS :Succinic acid sodium is an orally active anxiolytic.Formule :C4H6O4·xNaCouleur et forme :SolidMZ 1
CAS :MZ 1 is a BRD4 protein degrader based on PROTAC technology.Formule :C49H60ClN9O8S2Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :1002.64dCBP-1
CAS :dCBP-1 selectively degrades p300/CBP via CRBN, killing multiple myeloma cells.Formule :C51H63F2N11O10Degré de pureté :98.21% - 99.12%Couleur et forme :SolidMasse moléculaire :1028.11PHD-1-IN-1
CAS :PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).Formule :C13H8N4Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :220.23Ref: TM-T9627
1mg42,00€5mg92,00€10mg132,00€25mg231,00€50mg349,00€100mg522,00€200mg710,00€1mL*10mM (DMSO)90,00€Bempedoic acid
CAS :Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Formule :C19H36O5Degré de pureté :99.85% - 99.94%Couleur et forme :SolidMasse moléculaire :344.49Ref: TM-T3625
2mg34,00€5mg50,00€10mg70,00€25mg118,00€50mg207,00€100mg333,00€500mg797,00€1mL*10mM (DMSO)52,00€RGB-286638 free base
CAS :RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formule :C29H35N7O4Degré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :545.63GLPG0634 analog
CAS :GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.Formule :C23H18N6O2Degré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :410.43Ref: TM-T3076
1mg38,00€2mg50,00€5mg84,00€10mg137,00€25mg250,00€50mg442,00€100mg623,00€500mg1.305,00€1mL*10mM (DMSO)93,00€GSK 690 Hydrochloride
CAS :GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.Formule :C24H24ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.92Acetyl Pentapeptide-1 acetate
Acetyl Pentapeptide-1 acetate is an histone deacetylase inhibitor.Formule :C34H55N9O12Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :781.86Chlorogenic Acid
CAS :Chlorogenic acid is a natural phenol. Chlorogenic acid has anti-inflammatory, antitumor, and antimicrobial effects. Cost-effective and quality-assured.Formule :C16H18O9Degré de pureté :98.84% - 99.67%Couleur et forme :SolidMasse moléculaire :354.315,7,4'-Trimethoxyflavone
CAS :5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Formule :C18H16O5Degré de pureté :97.53%Couleur et forme :SolidMasse moléculaire :312.32MI-538
CAS :MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).
Formule :C27H25F3N8OSDegré de pureté :99.61% - 99.8%Couleur et forme :SolidMasse moléculaire :566.6Niraparib tosylate
CAS :Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
Formule :C19H20N4O·C7H8O3SDegré de pureté :99.34% - 99.87%Couleur et forme :SolidMasse moléculaire :492.59JAK3-IN-6
CAS :JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nMFormule :C19H18N4O3Degré de pureté :99.94% - 99.94%Couleur et forme :SolidMasse moléculaire :350.37KC7F2
CAS :KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.Formule :C16H16Cl4N2O4S4Degré de pureté :98% - 99.11%Couleur et forme :SolidMasse moléculaire :570.38Fucosterol
CAS :Fucosterol, from E. stolonifera, has anti-diabetic, anti-adipogenic, anti-cancer properties; it affects PPARα and C/EBPα to control fat cell formation.Formule :C29H48ODegré de pureté :98% - 99.68%Couleur et forme :White PowderMasse moléculaire :412.69PLX51107
CAS :PLX51107 is a potent and selective BET inhibitor (Kds: 1.6, 2.1, 1.7, and 5 nM for BRD2-BD1, BRD3-BD1, BRD4-BD1, and BRDT-BD1).Formule :C26H22N4O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :438.48Ref: TM-TQ0253
1mg52,00€2mg77,00€5mg113,00€10mg178,00€25mg313,00€50mg464,00€100mg672,00€1mL*10mM (DMSO)124,00€AMI-1
CAS :AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).Formule :C21H14N2Na2O9S2Degré de pureté :98% - 99.98%Couleur et forme :DrypowderMasse moléculaire :548.45XAV-939
CAS :XAV-939 (NVP-XAV939) shows the selective inhibition against Wnt/β-catenin-mediated transcription by tankyrase1/2 inhibition (IC50: 11/4 nM in cell-free assay).Formule :C14H11F3N2OSDegré de pureté :97.47% - 99.67%Couleur et forme :SolidMasse moléculaire :312.312-hexyl-4-Pentynoic Acid
CAS :2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.Formule :C11H18O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :182.26AMG-47a
CAS :AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formule :C29H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.56WHI-P154
CAS :WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formule :C16H14BrN3O3Degré de pureté :98% - 99.67%Couleur et forme :SolidMasse moléculaire :376.2Aurora kinase inhibitor-2
CAS :Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).Formule :C23H20N4O3Degré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :400.43Ref: TM-T9040
1mg63,00€5mg138,00€10mg200,00€25mg360,00€50mg532,00€100mg788,00€200mg1.063,00€1mL*10mM (DMSO)150,00€Atractylenolide I
CAS :Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formule :C15H18O2Degré de pureté :97.55% - 99.92%Couleur et forme :SolidMasse moléculaire :230.30M1001
CAS :M1001 is a HIF-2α agonist.Formule :C17H17N3O2SDegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :327.41,2-Dipalmitoyl-sn-glycerol
CAS :1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.Formule :C35H68O5Degré de pureté :97.84% - 99.78%Couleur et forme :SolidMasse moléculaire :568.91
