Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2613 produits trouvés pour "Chromatine/Épigénétique"
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Miltefosine
CAS :Miltefosine (HePC), effective oral drug for both visceral and cutaneous leishmaniasis, in clinical trials worldwide.Formule :C21H46NO4PDegré de pureté :98% - 99.94%Couleur et forme :White To Off-White PowderMasse moléculaire :407.57Hydralazine hydrochloride
CAS :Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.Formule :C8H9ClN4Degré de pureté :99.85% - 99.86%Couleur et forme :Yellow Crystals White Crystalline SolidMasse moléculaire :196.64MS417
CAS :MS417 (GTPL7512) is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weakFormule :C20H19ClN4O2SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :414.91A-485
CAS :A-485 is a p300/CBP histone acetyltransferase (HAT) inhibitor that inhibits p300 and CBP. A-485 has antitumor effects. Cost effective and quality assured.Formule :C25H24F4N4O5Degré de pureté :98.01% - 99.98%Couleur et forme :SolidMasse moléculaire :536.48Ref: TM-T14073
1mg88,00€5mg159,00€10mg273,00€25mg339,00€50mg404,00€100mg698,00€1mL*10mM (DMSO)187,00€WDR5-IN-6
CAS :WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus.WDR5-IN-6 is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.WDR5-IN-6Formule :C13H8Cl2N2O2SDegré de pureté :99.69%Couleur et forme :SoildMasse moléculaire :327.19Brepocitinib P-Tosylate
CAS :Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s of 17 nM and 23 nM, respectively).Formule :C25H29F2N7O4SDegré de pureté :99.82% - 99.97%Couleur et forme :SolidMasse moléculaire :561.6Glucosamine hydrochloride
CAS :Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.Formule :C6H13NO5·HClDegré de pureté :99.77%Couleur et forme :White Solid CrystallineMasse moléculaire :215.63MAT2A inhibitor 2
CAS :MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A).Formule :C18H24ClN3O3Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :365.85Bufexamac
CAS :Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.Formule :C12H17NO3Degré de pureté :99.73%Couleur et forme :Acicular CrystalMasse moléculaire :223.27Diflunisal
CAS :Diflunisal (Dolobid) is a cyclooxygenase (COX) Inhibitor, used as an anti-inflammatory analgesic.Formule :C13H8F2O3Degré de pureté :98.92% - 99.42%Couleur et forme :SolidMasse moléculaire :250.20Nicotinamide riboside
CAS :Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-
Formule :C11H15N2O5Degré de pureté :98.82% - 99.58%Couleur et forme :SolidMasse moléculaire :255.25ZEN-3694
CAS :ZEN-3694 (ZEN 3694) is a bromo-structural domain extra-terminal inhibitor (BETi) with activity in androgen signaling inhibitor (ASI) resistance models and canFormule :C19H19N5ODegré de pureté :98.94% - 99.76%Couleur et forme :SolidMasse moléculaire :333.39NU6140
CAS :NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).Formule :C23H30N6O2Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :422.52Ref: TM-T16359
2mg39,00€5mg60,00€10mg92,00€25mg177,00€50mg285,00€100mg414,00€200mg580,00€1mL*10mM (DMSO)67,00€Tulmimetostat
CAS :Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in the study of ovarian cancer and advancedFormule :C28H36ClN3O5SDegré de pureté :98.04% - 99.872%Couleur et forme :SolidMasse moléculaire :562.12Oltipraz
CAS :Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.Formule :C8H6N2S3Degré de pureté :98.79% - 99.77%Couleur et forme :SolidMasse moléculaire :226.34GNE-781
CAS :GNE-781: potent CBP inhibitor (IC50: 0.94 nM), also targets BRET/BRD4(1) (IC50: 6.2/5100 nM).Formule :C27H33F2N7O2Degré de pureté :99.25% - 99.64%Couleur et forme :SolidMasse moléculaire :525.59Ref: TM-T15405
1mg131,00€5mg281,00€10mg460,00€25mg765,00€50mg1.035,00€100mg1.404,00€1mL*10mM (DMSO)324,00€Golidocitinib
CAS :Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).Formule :C25H31N9O2Degré de pureté :98.87% - 99.88%Couleur et forme :SolidMasse moléculaire :489.57Tranylcypromine (2-PCPA) hydrochloride
CAS :Tranylcypromine (2-PCPA) HCl, a MAO inhibitor, treats major, dysthymic, and atypical depression.Formule :C9H11N·HClDegré de pureté :99.48% - 99.86%Couleur et forme :SolidMasse moléculaire :169.66Ilginatinib hydrochloride
CAS :Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable inhibitor of JAK2.Formule :C21H21ClFN7Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :425.89Ref: TM-T12266L2
1mg70,00€5mg150,00€10mg215,00€25mg358,00€50mg517,00€100mg707,00€200mg973,00€1mL*10mM (DMSO)166,00€iso-Azalansta
CAS :(2R,4S)-Azalanstat (Iso-Azalansta) is a selective heme oxygenase (HO) inhibitor that is used in the study of cardiovascular disease.Formule :C22H24ClN3O2SDegré de pureté :99.53% - 99.89%Couleur et forme :SoildMasse moléculaire :429.96(R)-CR8
CAS :(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.
Formule :C24H29N7ODegré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :431.53SMARCA-BD ligand 1 for Protac
CAS :SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2, the BAF ATPase subunit, based on the Protac technology for degrading SMARCA2Formule :C14H17N5ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :271.32Amifostine
CAS :Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.Formule :C5H15N2O3PSDegré de pureté :99.59%Couleur et forme :White SolidMasse moléculaire :214.22DC-05
CAS :DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).Formule :C25H25N3ODegré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :383.49Ref: TM-T15080
1mg66,00€5mg145,00€10mg236,00€25mg515,00€50mg858,00€100mg1.251,00€200mg1.684,00€1mL*10mM (DMSO)158,00€BMS-986158
CAS :BMS-986158: BET inhibitor, IC50 of 6.6 nM in SCLC, 5 nM in TNBC cells.Formule :C30H33N5O2Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :495.62Ref: TM-T14685
1mg87,00€5mg259,00€10mg465,00€25mg745,00€50mg1.026,00€100mg1.388,00€1mL*10mM (DMSO)283,00€LIN28 inhibitor LI71
CAS :LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM.Formule :C21H21NO3Degré de pureté :95.88%Couleur et forme :SolidMasse moléculaire :335.4Ref: TM-T11850
1mg107,00€5mg255,00€10mg414,00€25mg745,00€50mg1.063,00€100mg1.459,00€1mL*10mM (DMSO)341,00€ODM-207
CAS :ODM-207 (BET-IN-4) is a potent BRD4 inhibitor.Formule :C22H21N3O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :375.42Ref: TM-T10521
1mg44,00€5mg92,00€10mg133,00€25mg235,00€50mg339,00€100mg480,00€200mg660,00€1mL*10mM (DMSO)90,00€ZL0580
CAS :ZL0580 suppresses HIV by blocking Tat activation, halting transcription, and promoting repressive chromatin at the HIV promoter.Formule :C25H23F3N4O4SDegré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :532.53EHP-101
CAS :EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.Formule :C28H35NO3Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :433.58Ref: TM-T13289
1mg107,00€5mg227,00€10mg378,00€25mg620,00€50mg868,00€100mg1.169,00€1mL*10mM (DMSO)250,00€TAK-901
CAS :TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among othersFormule :C28H32N4O3SDegré de pureté :99.02% - 99.59%Couleur et forme :SolidMasse moléculaire :504.64Ref: TM-T2709
1mg35,00€5mg70,00€10mg104,00€25mg202,00€50mg329,00€100mg525,00€200mg748,00€1mL*10mM (DMSO)79,00€Levetiracetam
CAS :Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onsetFormule :C8H14N2O2Degré de pureté :99.67% - 99.86%Couleur et forme :White Crystalline PowderMasse moléculaire :170.21MAK683
CAS :MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).Formule :C20H17FN6ODegré de pureté :98.25% - 99.92%Couleur et forme :SolidMasse moléculaire :376.39Ref: TM-T15201
1mg50,00€5mg102,00€10mg178,00€25mg389,00€50mg575,00€100mg802,00€500mg1.665,00€1mL*10mM (DMSO)89,00€MS402
CAS :MS402 is a novel BD1-selective BET BrD inhibitor.Formule :C20H19ClN2O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :370.83Minocycline hydrochloride
CAS :Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Formule :C23H28ClN3O7Degré de pureté :99.28% - >99.99%Couleur et forme :Bright Yellow-Orange Amorphous Solid Crystalline YellowMasse moléculaire :493.94VTP50469
CAS :VTP50469 is a highly selective and orally active small molecule inhibitor of the Menin-MLL protein-protein interaction.Cost-effective and quality-assured.Formule :C32H47FN6O4SDegré de pureté :98.31% - 99.55%Couleur et forme :SolidMasse moléculaire :630.82Ref: TM-T13336
1mg164,00€5mg334,00€10mg401,00€25mg560,00€50mg715,00€100mg964,00€1mL*10mM (DMSO)465,00€A-395
CAS :A-395 blocks PRC2 (EZH2-EED-SUZ12) interactions, strongly inhibiting the complex with an IC50 of 18 nM.Formule :C26H35FN4O2SDegré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :486.65SNDX-5613
CAS :Revumenib (SNDX-5613) is a potent and selective oral inhibitor of menin-KMT2A interaction.Cost-effective and quality-assured.Formule :C32H47FN6O4SDegré de pureté :99.12% - 99.74%Couleur et forme :SolidMasse moléculaire :630.82Ref: TM-T12943
1mg73,00€2mg97,00€5mg160,00€10mg274,00€25mg542,00€50mg778,00€100mg1.074,00€1mL*10mM (DMSO)217,00€Pulrodemstat benzenesulfonate
CAS :Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent and orally inhibitor of lysine specific demethylase-1 (LSD1) with anticancer effect.Formule :C30H29F2N5O5SDegré de pureté :97.67%Couleur et forme :SolidMasse moléculaire :609.64Ref: TM-T11882
1mg60,00€2mg86,00€5mg124,00€10mg188,00€25mg329,00€50mg490,00€100mg710,00€1mL*10mM (DMSO)170,00€Fenbendazole
CAS :Fenbendazole (Fenbendazol) is an antinematodal benzimidazole used in veterinary medicine.Formule :C15H13N3O2SDegré de pureté :99.74%Couleur et forme :White To Yellowish PowderMasse moléculaire :299.35PKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Degré de pureté :95.42%Couleur et forme :SoildN-Desmethyltamoxifen hydrochloride
CAS :N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.Formule :C25H28ClNODegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :393.95FIDAS-5
CAS :FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.Formule :C15H13ClFNDegré de pureté :98.3% - 99.17%Couleur et forme :SolidMasse moléculaire :261.72Ref: TM-T11285
1mg56,00€2mg80,00€5mg110,00€10mg177,00€25mg314,00€50mg485,00€100mg700,00€500mg1.341,00€Lin28-let-7a antagonist 1
CAS :Lin28-let-7a antagonist 1, with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction，and shows a clear antagonistic effect against the Lin28-let-7a interaction.Formule :C31H29N5O7Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :583.59Ref: TM-T11851
1mg96,00€5mg205,00€10mg313,00€25mg562,00€50mg845,00€100mg1.243,00€1mL*10mM (DMSO)266,00€PT2399
CAS :PT2399, an oral HIF-2 inhibitor, blocks HIF-2α/1β dimerization, showing strong in vivo antitumor effects.Formule :C17H10F5NO4SDegré de pureté :98.8% - 99.45%Couleur et forme :SolidMasse moléculaire :419.32Ref: TM-T12675L
1mg88,00€5mg212,00€10mg318,00€25mg575,00€50mg848,00€100mg1.189,00€1mL*10mM (DMSO)233,00€JAK2 Inhibitor V
CAS :JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.Formule :C23H24N2ODegré de pureté :98.36% - 99.15%Couleur et forme :SolidMasse moléculaire :344.45Ref: TM-T3042
2mg37,00€5mg54,00€10mg80,00€25mg148,00€50mg259,00€100mg477,00€500mg1.063,00€1mL*10mM (DMSO)59,00€TRIM24/BRPF1-IN-2
CAS :TRIM24/BRPF1-IN-2 is a TRIM24/BRPF1 dual inhibitor with anticancer activity that inhibits the proliferation of prostate cancer cells.Formule :C20H22N2O4SDegré de pureté :98.69% - 99.13%Couleur et forme :SoildMasse moléculaire :386.47Uzansertib phosphate
CAS :Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase, inhibiting PIM1, PIM2 and PIM3.Formule :C26H29F3N5O7PDegré de pureté :99.75% - 99.79%Couleur et forme :SolidMasse moléculaire :611.51Chitosan oligosaccharide
CAS :Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine.Formule :C12H24N2O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :340.327L-2-Hydroxyglutaric acid disodium
CAS :L-2-Hydroxyglutaric acid disodium may affect epigenetics and contribute to renal cancer, inhibiting Mi-CK (Km 2.52 mM, Ki 11.13 mM).Formule :C5H6Na2O5Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :192.08N6-Cyclohexyladenosine
CAS :N6-Cyclohexyladenosine (CHA) is a selective agonist of A1 receptor with EC50 of 8.2 Nm.Formule :C16H23N5O4Degré de pureté :99.92% - 99.98%Couleur et forme :SolidMasse moléculaire :349.38
