Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2613 produits trouvés pour "Chromatine/Épigénétique"
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O6BTG-octylglucoside
CAS :O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).Formule :C24H34BrN5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :616.53SIRT5 inhibitor 3
CAS :SIRT5 inhibitor 3 is potent and competitive by inhibiting SIRT5 deacetylation, with potential in metabolic, cancer, neurodegenerative, cardiovascular .Formule :C22H12FN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.35Protein kinase inhibitor H-7 dihydrochloride
CAS :Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.Formule :C14H19Cl2N3O2SDegré de pureté :99.81%Couleur et forme :White Crystalline SolidMasse moléculaire :364.29DA-3003-1
CAS :DA-3003-1 (NSC 663284) is a Cdc25 dual specificity phosphatase inhibitor with antitumor activity and inhibits Cdc25B2, Cdc25A, Cdc25B2, and Cdc25C.Formule :C15H16ClN3O3Degré de pureté :99.27% - 99.79%Couleur et forme :SolidMasse moléculaire :321.76HDAC-IN-4
CAS :HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.Formule :C20H21N3O2Couleur et forme :SolidMasse moléculaire :335.4BAY-850
CAS :BAY-850 is ainhibitor of adenosine triphosphatase family protein 2 that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models.Formule :C38H44ClN5O3Degré de pureté :98% - 98%Couleur et forme :SolidMasse moléculaire :654.24(±)-1,2-Diolein
CAS :(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.Formule :C39H72O5Couleur et forme :SolidMasse moléculaire :620.99GSK-J2
CAS :GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.Formule :C22H23N5O2Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :389.45Ref: TM-T11476
1mg34,00€5mg71,00€10mg92,00€25mg157,00€50mg222,00€100mg329,00€200mg487,00€1mL*10mM (DMSO)101,00€Anti-PARP1 Antibody (8I163)
Anti-PARP1 Antibody (8I163) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (8I163) can be used in IHC-P.Couleur et forme :Odour LiquidAnti-PARP Antibody (1W26)
Anti-PARP Antibody (1W26) is a Mouse antibody targeting PARP. Anti-PARP Antibody (1W26) can be used in WB,IHC-P,IP.Couleur et forme :Odour LiquidAnti-PARP1 Antibody (6I459)
Anti-PARP1 Antibody (6I459) is an antibody targeting PARP1. Anti-PARP1 Antibody (6I459) can be used in ELISA, IHC.Couleur et forme :Odour LiquidAnti-PARP1 Antibody (7A800)
Anti-PARP1 Antibody (7A800) is an antibody targeting PARP1. Anti-PARP1 Antibody (7A800) can be used in ELISA, WB, IHC.Couleur et forme :Odour LiquidAnti-PARP1 Antibody (9E313)
Anti-PARP1 Antibody (9E313) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (9E313) can be used in IHC-P.Couleur et forme :Odour LiquidNSC 694621
CAS :NSC 694621 is a PCAF inhibitor that forms a covalent bond with Cys574, irreversibly inhibiting its acetyltransferase activity, inhibit proliferation,anticancer.Formule :C13H10N2O2SDegré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :258.3Anti-PARP1 Antibody (8S756)
Anti-PARP1 Antibody (8S756) is an antibody targeting PARP1. Anti-PARP1 Antibody (8S756) can be used in ELISA, WB, IHC, IF, FCM.Couleur et forme :Odour LiquidGintemetostat
CAS :Gintemetostat (KTX-1001) is a potent NSD2 inhibitor (IC50=0.001-0.01μM) for treating NSD2-dysregulated cancers.Formule :C25H26F4N8O2Couleur et forme :SolidMasse moléculaire :546.52CHZ868
CAS :CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.Formule :C22H19F2N5O2Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :423.42Ilunocitinib
CAS :Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.Formule :C17H17N7O2SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :383.43Ref: TM-T38571
1mg92,00€5mg230,00€10mg356,00€25mg713,00€50mg1.189,00€100mg1.791,00€200mg2.412,00€1mL*10mM (DMSO)251,00€7-Chloro-4-(piperazin-1-yl)quinoline
CAS :7-Cl-4-(piperazin-1-yl)quinolone: sirtuin inhibitor, serotonin uptake blocker, antimalarial (D10 IC50 1.18µM, K1 IC50 0.97µM).Formule :C13H14ClN3Degré de pureté :99.52%Couleur et forme :Light Yellow SolidMasse moléculaire :247.72SIRT-IN-3
CAS :SIRT-IN-3: potent SIRT1 inhibitor (IC50=17μM), 4x selective over SIRT2, 14x over SIRT3 (IC50s: 74μM & 235μM).Formule :C13H12N2OCouleur et forme :SolidMasse moléculaire :212.25Fenbendazole-d3
CAS :Fenbendazole-d3 is a deuterated compound of Fenbendazole. Fenbendazole has a CAS number of 43210-67-9. Fenbendazole is an antinematodal benzimidazole used in veterinary medicine.Formule :C15H10D3N3O2SCouleur et forme :SolidMasse moléculaire :302.37AMI-1 free acid
CAS :AMI-1: Potent reversible PRMT inhibitor; IC50: 8.8 μM (hPRMT1), 3.0 μM (yeast-Hmt1p); blocks substrate binding.
Formule :C21H16N2O9S2Degré de pureté :97.8%Couleur et forme :SolidMasse moléculaire :504.49XY1
CAS :XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), It is intended to be used as aFormule :C17H19N3O2Degré de pureté :97.74% - 99%Couleur et forme :SolidMasse moléculaire :297.35AZ960
CAS :AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).Formule :C18H16F2N6Degré de pureté :96.02% - 99.88%Couleur et forme :SolidMasse moléculaire :354.36ASP4132
CAS :ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.Formule :C46H51F3N6O8S2Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :937.06Ref: TM-T8432
1mg50,00€5mg114,00€10mg177,00€25mg321,00€50mg482,00€100mg677,00€200mg928,00€1mL*10mM (DMSO)185,00€4-(3-Chlorophenyl)-2(3H)-thiazolone
CAS :4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one: a thiazole used to make antifungals, antivirals, and anti-inflammatories.Formule :C9H6ClNOSDegré de pureté :95.311%Couleur et forme :SolidMasse moléculaire :211.67UNC0379
CAS :UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.Formule :C23H35N5O2Degré de pureté :94.41% - 99.97%Couleur et forme :SolidMasse moléculaire :413.56WP1066
CAS :WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formule :C17H14BrN3ODegré de pureté :98.92% - 99.73%Couleur et forme :SolidMasse moléculaire :356.22BI-7273
CAS :BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.Formule :C20H23N3O3Degré de pureté :97.37% - 99.57%Couleur et forme :SolidMasse moléculaire :353.41TCS PIM-1 1
CAS :TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an IC50 of 50 nM, selective over MEK1/2 and Pim-2.Formule :C18H11BrN2O2Degré de pureté :97% - 97.98%Couleur et forme :SolidMasse moléculaire :367.2Ref: TM-T2253
1mg34,00€5mg60,00€10mg94,00€25mg177,00€50mg269,00€100mg401,00€200mg580,00€1mL*10mM (DMSO)92,00€Rucaparib monocamsylate
CAS :Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.
Formule :C29H34FN3O5SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :555.66PI-1840
CAS :PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formule :C22H26N4O3Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :394.473-methyl-1,2-dihydroquinolin-2-one
CAS :3-methyl-1,2-dihydroquinolin-2-one is the first known micromolar inhibitors of the ATAD2 bromodomain.Formule :C10H9NODegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :159.18Ref: TM-T50035
1mg35,00€5mg77,00€10mg103,00€25mg170,00€50mg250,00€100mg354,00€200mg480,00€1mL*10mM (DMSO)62,00€PF-06409577
CAS :PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).Formule :C19H16ClNO3Degré de pureté :95.17% - 98.21%Couleur et forme :SolidMasse moléculaire :341.79Ref: TM-T4427
1mg34,00€2mg43,00€5mg63,00€10mg100,00€25mg200,00€50mg334,00€100mg537,00€200mg762,00€1mL*10mM (DMSO)71,00€NSC 228155
CAS :NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Formule :C11H6N4O4SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :290.25Ref: TM-T6908
2mg34,00€5mg48,00€10mg63,00€25mg117,00€50mg178,00€100mg334,00€200mg469,00€1mL*10mM (DMSO)50,00€653-47
CAS :653-47 enhances the effects of 666-15 on inhibiting CREB and is a mild CREB inhibitor itself (IC50: 26.3μM).Formule :C20H19ClN2O3Couleur et forme :SolidMasse moléculaire :370.83Aurora kinase inhibitor-3
CAS :Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Formule :C21H18F3N5ODegré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :413.4Ref: TM-T5524
1mg70,00€2mg95,00€5mg160,00€10mg250,00€25mg424,00€50mg612,00€100mg842,00€200mg1.159,00€1mL*10mM (DMSO)170,00€BEBT-908
CAS :BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits HDAC (0.1 μM≤IC50≤1 μM).Formule :C23H25N9O3SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :507.57Ref: TM-T16529
1mg94,00€5mg222,00€10mg334,00€25mg562,00€50mg802,00€100mg1.063,00€200mg1.459,00€1mL*10mM (DMSO)249,00€PF-CBP1
CAS :PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).Formule :C29H36N4O3Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :488.62Ritlecitinib
CAS :Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity of JAK1/2.Cost-effective and quality-assured.Formule :C15H19N5ODegré de pureté :98.82% - 99.92%Couleur et forme :SolidMasse moléculaire :285.34Ref: TM-T5382
2mg37,00€5mg52,00€10mg90,00€25mg205,00€50mg290,00€100mg408,00€200mg595,00€1mL*10mM (DMSO)73,00€6-Bromo-3-methyl-1,4-dihydroquinazolin-2-one
CAS :CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).Formule :C9H9BrN2ODegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :241.08Ref: TM-T8609
1mg58,00€5mg116,00€10mg172,00€25mg281,00€50mg396,00€100mg537,00€200mg712,00€1mL*10mM (DMSO)107,00€Delgocitinib EtOH
CAS :Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Formule :C18H24N6O2Couleur et forme :SolidMasse moléculaire :356.43Paris saponin VII
CAS :Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.Formule :C51H82O21Degré de pureté :99.51% - 99.63%Couleur et forme :SolidMasse moléculaire :1031.18O-304
CAS :O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formule :C16H11Cl2N3O2SDegré de pureté :99.84% - ≥98%Couleur et forme :SolidMasse moléculaire :380.25Ref: TM-T7362
1mg63,00€2mg92,00€5mg137,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€500mg1.728,00€1mL*10mM (DMSO)150,00€ZINC13466751
CAS :ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 µM).Formule :C20H21N5O2Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :363.41UNC1079
CAS :UNC1079 is an selective L3MBTL3 domain inhibitor
Formule :C28H42N4O2Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :466.66Senaparib
CAS :Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.Formule :C24H20F2N6O3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :478.45Ref: TM-T9593
1mg46,00€2mg59,00€5mg87,00€10mg153,00€25mg274,00€50mg432,00€100mg638,00€1mL*10mM (DMSO)96,00€TP-064
CAS :TP-064: Potent, selective PRMT4 inhibitor, IC50 < 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation at 43nM.Formule :C28H34N4O2Degré de pureté :97.85%Couleur et forme :SolidMasse moléculaire :458.6Ref: TM-T28996
1mg35,00€2mg50,00€5mg74,00€10mg113,00€25mg231,00€50mg462,00€100mg673,00€1mL*10mM (DMSO)75,00€4-Phenylbutyric acid
CAS :4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.Formule :C10H12O2Degré de pureté :98.40% - 99.76%Couleur et forme :SolidMasse moléculaire :164.2KDM4D-IN-1
CAS :KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).Formule :C11H7N5ODegré de pureté :99.51% - >99.99%Couleur et forme :SolidMasse moléculaire :225.21Ref: TM-T4214
1mg73,00€5mg158,00€10mg245,00€25mg495,00€50mg795,00€100mg1.161,00€1mL*10mM (DMSO)168,00€
