Altération de l'ADN/réparation de l'ADN
Les inhibiteurs de la réparation des dommages à l'ADN sont des composés qui interfèrent avec les processus impliqués dans la détection et la réparation des dommages à l'ADN. Ces inhibiteurs sont essentiels pour étudier les mécanismes de la stabilité génomique, de la mutagenèse et de la réponse aux dommages à l'ADN. Ils sont également importants dans la recherche sur le cancer, car de nombreuses tumeurs dépendent de voies spécifiques de réparation de l'ADN pour survivre. En inhibant ces voies, les inhibiteurs de la réparation des dommages à l'ADN peuvent améliorer l'efficacité de la chimiothérapie et de la radiothérapie. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité de la réparation des dommages à l'ADN pour soutenir vos recherches en biologie moléculaire, oncologie et pharmacologie.
Sous-catégories appartenant à la catégorie "Altération de l'ADN/réparation de l'ADN"
- ATM/ATR(71 produits)
- Alkylation de l'ADN(11 produits)
- Méthyltransférase de l’ADN(422 produits)
- Gyrase de l’ADN(11 produits)
- ADN-PK(51 produits)
- MTH1(1 produits)
- Antimétabolite nucléosidique/analogue(1.388 produits)
- Transcriptase inverse(43 produits)
- Sirtuine(88 produits)
- Télomérase(33 produits)
- Topoisomérase(136 produits)
Affichez 3 plus de sous-catégories
958 produits trouvés pour "Altération de l'ADN/réparation de l'ADN"
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ITF3756
CAS :<p>ITF3756 is a selective HDAC6 inhibitor.</p>Formule :C13H11N5O2SDegré de pureté :97.74%Couleur et forme :SolidMasse moléculaire :301.32ATR-IN-10
CAS :<p>ATR-IN-10 is a potent and highly selective inhibitor of ATR kinase (IC50: 2.978 μM).</p>Formule :C27H24N4OCouleur et forme :SolidMasse moléculaire :420.51Hepsulfam
CAS :<p>Hepsulfam is an anticancer agent. It also displays excellent antileukemic activity (a median IC50: 0.91 μg/mL in a panel of different tumors).</p>Formule :C7H18N2O6S2Couleur et forme :SolidMasse moléculaire :290.36CM-579
CAS :<p>CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.</p>Formule :C29H40N4O3Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :492.65C-333H
CAS :<p>C-333H is a new PPARalpha/gamma dual agonist.</p>Formule :C28H26N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :486.52F-14512
CAS :<p>F-14512, a DNA topoisomerase II inhibitor, is used potentially for the treatment of acute myeloid leukemia.</p>Formule :C33H47N5O8Couleur et forme :SolidMasse moléculaire :641.76MHY908
CAS :<p>MHY908, a novel inhibitor of melanogenesis, potently inhibits mushroom tyrosinase activity in a dose-dependent manner.</p>Formule :C17H14ClNO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.82S26948
CAS :<p>S26948 is a PPARγ agonist.</p>Formule :C28H25NO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :519.57Topoisomerase IIα-IN-1
CAS :<p>Topoisomerase IIα-IN-1 (compound 2) is a DNA-binding ligands and a potent inhibitor of TopoIIα, a topoisomerase.</p>Formule :C22H20N4O5Couleur et forme :SolidMasse moléculaire :420.42KRP-297
CAS :<p>KRP297 is a PPAR agonist potentially for the treatment of type 2 diabetes and dyslipidemia.</p>Formule :C20H17F3N2O4SCouleur et forme :SolidMasse moléculaire :438.42MPT0G211
CAS :<p>MPT0G211: oral HDAC6 inhibitor with IC50=0.291 nM, 1000x selectivity, neuroprotective, anti-metastatic, crosses blood-brain barrier for Alzheimer's.</p>Formule :C17H15N3O2Degré de pureté :98% - 99.88%Couleur et forme :SolidMasse moléculaire :293.32ST247
CAS :<p>ST247: Potent PPARβ/δ inverse agonist, blocks CCL2 expression and agonist-driven PPARβ/δ transcription, promotes co-repressor interaction.</p>Formule :C19H26N2O5S2Couleur et forme :SolidMasse moléculaire :426.55SW155246
CAS :<p>SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).</p>Formule :C16H11ClN2O5SDegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :378.79XR 5944
CAS :<p>XR 5944 is an effective DNA binder that stabilizes topoisomerase-dependent cleavage and has shown superior efficacy in a variety of mouse and human tumor models</p>Formule :C34H34N8O2Degré de pureté :98.29% - 98.66%Couleur et forme :SolidMasse moléculaire :586.69Huanglongmycin N
CAS :<p>Huanglongmycin N acts as a DNA topoisomerase I inhibitor, demonstrating an EC50 value of 14 μM.</p>Formule :C19H16O5Couleur et forme :SolidMasse moléculaire :324.33DNA-PK-IN-1
CAS :<p>DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-PK-IN-1 has potential for cancer disease research.</p>Formule :C23H26N8O2Couleur et forme :SolidMasse moléculaire :446.5Eicosatetraynoic acid
CAS :<p>ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).</p>Formule :C20H24O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.4DNA-PK-IN-3
CAS :<p>DNA-PK-IN-3 is a potent DNA-PK inhibitor, enhancing radio/chemotherapy and reducing tumors with limited side effects.</p>Formule :C19H19N9OCouleur et forme :SolidMasse moléculaire :389.41TFMB-(S)-2-HG
CAS :<p>TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.</p>Formule :C13H11F3O4Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :288.22CP 775146
CAS :<p>PPARα agonist</p>Formule :C26H33NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :423.54DC_501
CAS :<p>DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.</p>Formule :C25H23Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.38(S)-Gyramide A
CAS :<p>(S)-Gyramide A is a bacterial DNA gyrase inhibitor that acts by exhibiting antimicrobial activity and inhibiting bacterial cell division.</p>Formule :C21H27FN2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.515-Aza-4'-thio-2'-deoxycytidine
CAS :<p>5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].</p>Formule :C8H12N4O3SCouleur et forme :SolidMasse moléculaire :244.27Topoisomerase II inhibitor 4
CAS :<p>Compound E17, a topoisomerase II inhibitor, halts cell cycle at G2/M, possesses anticancer properties and cytotoxic effects.</p>Formule :C25H25N5O4Couleur et forme :SolidMasse moléculaire :459.5Lexitropsin
CAS :<p>Lexitropsin is a novel anticancer drug.</p>Formule :C20H29N5O4Couleur et forme :SolidMasse moléculaire :403.48ATR-IN-16
CAS :<p>ATR-IN-16 (compound 46) is an ATR kinase inhibitor with potent anticancer effects in LoVo cells, IC50 of 410 nM.</p>Formule :C19H25N7OCouleur et forme :SolidMasse moléculaire :367.45Piroxantrone
CAS :<p>Piroxantrone (CI942; PD111815) is an anthrapyrazole antibiotic that disrupts DNA replication and repair, with limited cardiotoxicity and antineoplastic range.</p>Formule :C21H25N5O4Couleur et forme :SolidMasse moléculaire :411.45Procarbazine free base
CAS :<p>Procarbazine: chemo drug for Hodgkin's, brain cancer; liver-activated; MAO inhibitor.</p>Formule :C12H19N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :221.3MLR24
CAS :<p>MLR24 is a selective modulator of PPARγ that acts by displaying robust anti-diabetic activity.</p>Formule :C28H24F3NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.49CAY10744
CAS :<p>CAY10744, a topoisomerase II-α inhibitor (78.9% at 20 μM), blocks cancer cell proliferation with varying IC50s and induces apoptosis in T47D cells.</p>Formule :C24H16ClNO2Couleur et forme :SolidMasse moléculaire :385.84Anticancer agent 75
CAS :<p>Anticancer agent 75: potent, selective, less toxic to kidneys than Doxorubicin by 35x, with antiplasmodial properties.</p>Formule :C22H24N2OCouleur et forme :SolidMasse moléculaire :332.44Givinostat hydrochloride monohydrate
CAS :<p>Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor.</p>Formule :C24H27N3O4·HCl·H2ODegré de pureté :97.97% - 99.51%Couleur et forme :SolidMasse moléculaire :475.97ZINC08438472
CAS :<p>ZINC08438472 is a selective peroxisome proliferator-activated receptors-α agonist.</p>Formule :C25H25NO8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :499.53Topoisomerase I inhibitor 4
CAS :<p>Topoisomerase I inhibitor 4 targets cancer cells like HepG2, A549, MCF-7, HeLa with low IC50, promising for research.</p>Formule :C23H19FN4OCouleur et forme :SolidMasse moléculaire :386.42WEHI-150
CAS :<p>WEHI-150, a mitoxantrone analog, cross-links DNA, targets methylated CpG, halts transcription, and avoids guanine N-2 interaction.</p>Formule :C22H30N6O4Couleur et forme :SolidMasse moléculaire :442.51Exatecan mesylate dihydrate
CAS :<p>Exatecan mesylate dihydrate (DX-8951), a DNA topoisomerase I inhibitor, exhibits an IC50 of 2.2 μM (0.975 μg/mL) and is utilized in cancer research [1] [2] [3].</p>Formule :C25H30FN3O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :567.58ZINC17167211
CAS :<p>ZINC17167211 is a selective peroxisome proliferator-activated receptors-α agonist.</p>Formule :C24H17FN2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :480.46Ceralasertib formate
CAS :<p>Ceralasertib: an oral ATR kinase inhibitor that blocks CHK1 phosphorylation, disrupts DNA repair, and triggers tumor cell apoptosis.</p>Formule :C21H26N6O4SCouleur et forme :SolidMasse moléculaire :458.54CAY10514
CAS :<p>CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPARα and PPARγ with EC50 values of 0.173 and 0.642 μM, respectively.</p>Formule :C20H28O4Couleur et forme :SolidMasse moléculaire :332.43Ranimustine
CAS :<p>Ranimustine (MCNU) can be used for polycythemia vera and chronic myelogenous leukemia research, which is a nitrosourea alkylating agent [1] [3] [4].</p>Formule :C10H18ClN3O7Couleur et forme :SolidMasse moléculaire :327.72AA-CW236
CAS :<p>AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).</p>Formule :C17H16ClF3N4O2Couleur et forme :SolidMasse moléculaire :400.78PPARδ agonist 8
CAS :<p>Pparδ agonist 8 is a potent agonist of Pparδ. Pparδ agonist 8 has potential for the study of nonalcoholic fatty liver disease (NAFLD).</p>Formule :C25H29NO5Couleur et forme :SolidMasse moléculaire :423.5DRF 2519
CAS :<p>DRF 2519 is an activator of PPAR-alpha and PPAR-gamma.</p>Formule :C20H18N2O5SCouleur et forme :SolidMasse moléculaire :398.43CLX 0921
CAS :<p>CLX 0921, a PPAR gamma agonist, is used potentially for the treatment of type 2 diabetes.</p>Formule :C28H25NO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :519.57ARTD10/PARP10-IN-1
CAS :<p>ARTD10/PARP10-IN-1 is a PARP inhibitor that inhibits ARTD8/PARP14 and has anticancer and antitumour activity for the study of prostate cancer.</p>Formule :C12H12N2O4Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :248.23Gartisertib
CAS :<p>Gartisertib (VX-803) is an ATR inhibitor with anti-tumor activity, inhibiting the anti-proliferative effects induced in ccRCC cells.</p>Formule :C25H29F2N9O3Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :541.55NSC-311068
CAS :<p>NSC-311068: A selective TET1 inhibitor, reducing 5hmC and AML cell viability with high TET1.</p>Formule :C10H6N4O4SCouleur et forme :SolidMasse moléculaire :278.24Daniquidone
CAS :<p>Daniquidone (Batracylin) is a potent dual inhibitor of DNA topoisomerase I and DNA topoisomerase II with cytotoxic and antiproliferative activity for neoplasms</p>Formule :C15H11N3ODegré de pureté :98.39% - 99.52%Couleur et forme :SolidMasse moléculaire :249.27ICRF-196
CAS :<p>ICRF-196 is a Topoisomerase II Inhibitor and antineoplastic agent.</p>Formule :C12H18N4O4Couleur et forme :SolidMasse moléculaire :282.313-Oxo-9E,11E-octadecadienoic acid
CAS :<p>13-Oxo-9E,11E-octadecadienoic acid from tomato juice, an isomer of 9-oxo-ODA, activates PPARα and lowers triglycerides in diabetic mice.</p>Formule :C18H30O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :294.43Tetrahydrouridine
CAS :<p>Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.</p>Formule :C9H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.23DC_517
CAS :<p>DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM).</p>Formule :C33H35N3O2Couleur et forme :SolidMasse moléculaire :505.65Seladelpar Lysine dihydrate
CAS :<p>Seladelpar lysine, a selective PPAR-δ agonist, is used for the therapy of Homozygous Familial Hypercholesterolemia (HoFH).</p>Formule :C27H41F3N2O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :626.68BNS-22
CAS :<p>BNS-22 is a DNA topoisomerase II (Topo II) inhibitor, induces mitotic abnormalities and exhibits antiproliferative activity against human cancer cells.</p>Formule :C24H25NO5Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :407.46AM-3102
CAS :<p>AM-3102: An OEA analog; boosts PPARα, delays eating, resists hydrolysis, mimics OEA potency, and weakly binds CB1/CB2.</p>Formule :C21H41NO2Couleur et forme :SolidMasse moléculaire :339.56DNA-PK-IN-4
CAS :<p>DNA-PK-IN-4, an imidazolinone, targets DNA-PKcs to hinder tumor DNA repair and induce apoptosis, showing cancer research potential.</p>Formule :C20H24N6O3Couleur et forme :SolidMasse moléculaire :396.44G3335
CAS :<p>H-Trp-Glu-OH: Selective, reversible PPARγ modulator; cell-permeable; Kd ~8μM; potential diabetes lead.</p>Formule :C16H19N3O5Couleur et forme :SolidMasse moléculaire :333.34SKLB-197
CAS :<p>SKLB-197 targets ATR, inhibiting it at 0.013 μM, and is inactive on 402 other kinases, showing potent antitumor effects on ATM-deficient tumors.</p>Formule :C25H24N6OCouleur et forme :SolidMasse moléculaire :424.5ATR-IN-15
CAS :<p>ATR-IN-15, an ATR kinase inhibitor, has an IC50 of 8 nM and also targets LoVo cells, DNA-PK, and PI3K with higher IC50 values.</p>Formule :C19H22N8OCouleur et forme :SolidMasse moléculaire :378.43PPARγ agonist 6
CAS :<p>PPARγ agonist 6 (Compound 12) is a potent agonist of selective PPARγ. PPARγ agonist 6 has potential for cancer disease research.</p>Formule :C27H26N2O4Couleur et forme :SolidMasse moléculaire :442.51PPARγ agonist 5
CAS :<p>PPARγ agonist 5 is a selective and potent PPARγ agonist that has shown research potential for cancer disease.</p>Formule :C33H31N5OCouleur et forme :SolidMasse moléculaire :513.63CP-67804
CAS :<p>CP 67804 enhances topoisomerase II-mediated DNA cleaving.</p>Formule :C18H13F2NO4Couleur et forme :SolidMasse moléculaire :345.3DNA-PK-IN-7
CAS :<p>DNA-PK-IN-7 is a potent DNA-PK inhibitor (IC50= 1 nM) (WO2021104277A1, compound 5).</p>Formule :C19H21N9O2Couleur et forme :SolidMasse moléculaire :407.43Saroglitazar
CAS :<p>Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.</p>Formule :C25H29NO4SDegré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :439.5717(S)-HDHA
CAS :<p>17(S)-HDHA: A DHA derivative in human blood/cells and mouse brain; leads to 17(S)-resolvins; inhibits IL-1β and leukocyte trafficking.</p>Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.49ARH-049020
CAS :<p>ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.</p>Formule :C24H31NO6Degré de pureté :97.19% - 99.82%Couleur et forme :SolidMasse moléculaire :429.51Daltroban
CAS :<p>Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.</p>Formule :C16H16ClNO4SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :353.82DNMT3A-IN-1
CAS :<p>DNMT3A-IN-1 is a potent, selective DNMT3A inhibitor with KI 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).</p>Formule :C30H38N6O4Couleur et forme :SolidMasse moléculaire :546.66NCI172112
CAS :<p>NCI172112 is is used to develop antitumor agents effective against CNS tumors.</p>Formule :C14H23Cl2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.26MD001
CAS :<p>MD001 is a PPARα/γ agonist, binds at Kds 9.55/0.14 μM, boosts transcription, and regulates glucose, lipid levels in diabetic mice.</p>Formule :C25H18O5Couleur et forme :SolidMasse moléculaire :398.41DB-959 (salt)
CAS :<p>DB-959, a PPAR agonist, is used potentially for the treatment of Alzheimer's disease.</p>Formule :C25H27NNaO5Couleur et forme :SolidMasse moléculaire :444.483XR-5000
CAS :<p>XR-5000 is a DNA topoisomerase I and II inhibitor.</p>Formule :C18H19N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :293.36Topoisomerase II inhibitor 8
CAS :<p>Compound 22 is a potent topoisomerase II inhibitor (IC50=0.52μM), with strong anti-proliferative effects, arresting cells at G2/M.</p>Formule :C14H8N4O3SCouleur et forme :SolidMasse moléculaire :312.36-Methyl-5-azacytidine
CAS :<p>6-Methyl-5-azacytidine is a potent DNMT inhibitor.</p>Formule :C9H14N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :258.23TZD18
CAS :<p>TZD18, a novel PPAR alpha/gamma dual agonist, inhibits cell growth and induces apoptosis in human glioblastoma T98G cells.</p>Formule :C27H27NO5SCouleur et forme :SolidMasse moléculaire :477.57CP-67015
CAS :<p>CP 67015 has an inhibitory effect on the function of topoisomerase, and is a direct mutagen in mammalian cells, which has effects on gene and chromosome levels.</p>Formule :C17H12F2N2O3Couleur et forme :SolidMasse moléculaire :330.29NS-220
CAS :<p>NS-220 selectively activates PPAR-alpha, reducing triglycerides and glucose in KK-Ay mice, also altering lipoproteins.</p>Formule :C21H27NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :373.44Dihydro-5-azacytidine acetate
CAS :<p>Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1</p>Formule :C10H18N4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.27NU-7163
CAS :<p>NU-7163 is a potent and selective inhibitor of ATP-competitive DNA-PK.</p>Formule :C18H17NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.33GW409544
CAS :<p>GW409544 is an agonist of PPAR-alpha and PPAR-gamma.</p>Formule :C31H30N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.58L-796449
CAS :<p>L-796449 is an agonist of PPAR-gamma.</p>Formule :C28H27ClO4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.03Cas9-IN-2
CAS :<p>Cas9-IN-2, an apo-Cas9 binder, inhibits Cas9 (IC50=246 μM), blocking Cas9:gRNA formation, regulating Cas9 function.</p>Formule :C21H27N5O4S2Couleur et forme :SolidMasse moléculaire :477.6PR-104
CAS :<p>PR-104: hypoxia-activated DNA cross-linker, pre-prodrug for nitrogen mustard, converts to PR-104A in tumors.</p>Formule :C14H20BrN4O12PSCouleur et forme :SolidMasse moléculaire :579.27RG-12525
CAS :<p>RG-12525（NID 525） is an orally available, selective and competitive leukotriene D (LTD) antagonist that inhibits LTC4, LTD4 and LTE4-induced contraction of</p>Formule :C25H21N5O2Degré de pureté :95.49%Couleur et forme :SolidMasse moléculaire :423.47Sabarubicin
CAS :<p>Sabarubicin: a doxorubicin analogue with potent antitumor effects; superior in DNA fragmentation and topoisomerase II poisoning.</p>Formule :C32H37NO13Couleur et forme :SolidMasse moléculaire :643.64Topoisomerase I inhibitor 6
CAS :<p>Topoisomerase I inhibitor 6 traps DNA-Top1 complex, shows low non-cancer cell cytotoxicity, and has research value.</p>Formule :C23H21N7OCouleur et forme :SolidMasse moléculaire :411.46LT175
CAS :<p>LT175 is a dual PPARα/γ partial agonist, insulin sensitizer, orally active, with lower adipogeny (EC50: hPPARα 0.22μm, mPPARα 0.26μm, hPPARγ 0.48μm).</p>Formule :C21H18O3Couleur et forme :SolidMasse moléculaire :318.37Romazarit
CAS :<p>Romazarit, a propionic acid derivative, is used as a PPARα agonist and acts as an antirheumatic drug.</p>Formule :C15H16ClNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :309.74Pparδ agonist 7
CAS :<p>Pparδ agonist 7 is a potent agonist of Pparδ.</p>Formule :C25H25NO5Couleur et forme :SolidMasse moléculaire :419.47Resminostat
CAS :<p>Resminostat (4SC-201) is an orally bioavailable inhibitor of histone deacetylases (HDACs) with potential antineoplastic activity.</p>Formule :C16H19N3O4SDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :349.4KDT 501 potassium
CAS :<p>KDT 501, a PPAR agonist and G protein-coupled receptor (GPR) 120 agonist, is used potentially for the treatment of type 2 diabetes.</p>Formule :C21H34KO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.596PPARγ agonist 4
CAS :<p>PPARγ agonist 4 (Compound 18b), a potent and selective PPARγ agonist, demonstrates antitumor efficacy only when used in conjunction with Imatinib.</p>Formule :C24H22FN3OCouleur et forme :SolidMasse moléculaire :387.45DSO-5a
CAS :<p>DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.</p>Formule :C23H24N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.45DB-959 (free base)
CAS :<p>DB-959 is a potential agonist of PPAR.</p>Formule :C25H27NO5Couleur et forme :SolidMasse moléculaire :421.493,6-Diamino-9(10H)-acridone
CAS :<p>3,6-Diamino-9(10H)-acridone is an inhibitor of topoisomerase [1].</p>Formule :C13H11N3OCouleur et forme :SolidMasse moléculaire :225.25Mitobronitol
CAS :<p>Mitobronitol, a brominated mannitol analog, is an alkylating anticancer drug that aids in reducing allogeneic bone marrow transplant risks.</p>Formule :C6H12Br2O4Couleur et forme :SolidMasse moléculaire :307.97PPARα/δ agonist 1
CAS :<p>PPARα/δ agonist 1 is a potent PPARα/PPARδ dual agonist with EC50 values of 7.0 nM for PPARα and 8.4 nM for PPARδ.</p>Formule :C22H22F3N3O5Couleur et forme :SolidMasse moléculaire :465.42NK314
CAS :<p>NK314, a benzo[c]phenanthridine, inhibits topoisomerase II causing DNA breaks within 1h, even without proteinase K digestion.</p>Formule :C22H20ClNO4Couleur et forme :SolidMasse moléculaire :397.85DNA-PK-IN-5
CAS :<p>DNA-PK-IN-5: potent DNA-PK inhibitor, reduces tumor repair, induces apoptosis, enhances radiotherapy, overcomes resistance.</p>Formule :C21H22N8O2Couleur et forme :SolidMasse moléculaire :418.45Mipicoledine
CAS :<p>DM-CHOC-PEN is a DNA alkylation agent that may be used to treat brain cancer.</p>Formule :C35H48Cl5NO4Couleur et forme :SolidMasse moléculaire :724.02
