Altération de l'ADN/réparation de l'ADN
Les inhibiteurs de la réparation des dommages à l'ADN sont des composés qui interfèrent avec les processus impliqués dans la détection et la réparation des dommages à l'ADN. Ces inhibiteurs sont essentiels pour étudier les mécanismes de la stabilité génomique, de la mutagenèse et de la réponse aux dommages à l'ADN. Ils sont également importants dans la recherche sur le cancer, car de nombreuses tumeurs dépendent de voies spécifiques de réparation de l'ADN pour survivre. En inhibant ces voies, les inhibiteurs de la réparation des dommages à l'ADN peuvent améliorer l'efficacité de la chimiothérapie et de la radiothérapie. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité de la réparation des dommages à l'ADN pour soutenir vos recherches en biologie moléculaire, oncologie et pharmacologie.
Sous-catégories appartenant à la catégorie "Altération de l'ADN/réparation de l'ADN"
- ATM/ATR(71 produits)
- Alkylation de l'ADN(11 produits)
- Méthyltransférase de l’ADN(421 produits)
- Gyrase de l’ADN(11 produits)
- ADN-PK(51 produits)
- MTH1(1 produits)
- Antimétabolite nucléosidique/analogue(1.388 produits)
- Transcriptase inverse(43 produits)
- Sirtuine(88 produits)
- Télomérase(33 produits)
- Topoisomérase(136 produits)
Affichez 3 plus de sous-catégories
957 produits trouvés pour "Altération de l'ADN/réparation de l'ADN"
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ATR-IN-10
CAS :<p>ATR-IN-10 is a potent and highly selective inhibitor of ATR kinase (IC50: 2.978 μM).</p>Formule :C27H24N4OCouleur et forme :SolidMasse moléculaire :420.51S26948
CAS :<p>S26948 is a PPARγ agonist.</p>Formule :C28H25NO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :519.57F-14512
CAS :<p>F-14512, a DNA topoisomerase II inhibitor, is used potentially for the treatment of acute myeloid leukemia.</p>Formule :C33H47N5O8Couleur et forme :SolidMasse moléculaire :641.76MHY908
CAS :<p>MHY908, a novel inhibitor of melanogenesis, potently inhibits mushroom tyrosinase activity in a dose-dependent manner.</p>Formule :C17H14ClNO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.82Topoisomerase IIα-IN-1
CAS :<p>Topoisomerase IIα-IN-1 (compound 2) is a DNA-binding ligands and a potent inhibitor of TopoIIα, a topoisomerase.</p>Formule :C22H20N4O5Couleur et forme :SolidMasse moléculaire :420.42ST247
CAS :<p>ST247: Potent PPARβ/δ inverse agonist, blocks CCL2 expression and agonist-driven PPARβ/δ transcription, promotes co-repressor interaction.</p>Formule :C19H26N2O5S2Couleur et forme :SolidMasse moléculaire :426.55XR 5944
CAS :<p>XR 5944 is an effective DNA binder that stabilizes topoisomerase-dependent cleavage and has shown superior efficacy in a variety of mouse and human tumor models</p>Formule :C34H34N8O2Degré de pureté :98.29% - 98.66%Couleur et forme :SolidMasse moléculaire :586.69Huanglongmycin N
CAS :<p>Huanglongmycin N acts as a DNA topoisomerase I inhibitor, demonstrating an EC50 value of 14 μM.</p>Formule :C19H16O5Couleur et forme :SolidMasse moléculaire :324.33Eicosatetraynoic acid
CAS :<p>ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).</p>Formule :C20H24O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.4TFMB-(S)-2-HG
CAS :<p>TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.</p>Formule :C13H11F3O4Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :288.22CP 775146
CAS :<p>PPARα agonist</p>Formule :C26H33NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :423.54Procarbazine free base
CAS :<p>Procarbazine: chemo drug for Hodgkin's, brain cancer; liver-activated; MAO inhibitor.</p>Formule :C12H19N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :221.3CAY10744
CAS :<p>CAY10744, a topoisomerase II-α inhibitor (78.9% at 20 μM), blocks cancer cell proliferation with varying IC50s and induces apoptosis in T47D cells.</p>Formule :C24H16ClNO2Couleur et forme :SolidMasse moléculaire :385.84Givinostat hydrochloride monohydrate
CAS :<p>Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor.</p>Formule :C24H27N3O4·HCl·H2ODegré de pureté :97.97% - 99.51%Couleur et forme :SolidMasse moléculaire :475.97ZINC08438472
CAS :<p>ZINC08438472 is a selective peroxisome proliferator-activated receptors-α agonist.</p>Formule :C25H25NO8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :499.53ZINC17167211
CAS :<p>ZINC17167211 is a selective peroxisome proliferator-activated receptors-α agonist.</p>Formule :C24H17FN2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :480.46CLX 0921
CAS :<p>CLX 0921, a PPAR gamma agonist, is used potentially for the treatment of type 2 diabetes.</p>Formule :C28H25NO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :519.57ARTD10/PARP10-IN-1
CAS :<p>ARTD10/PARP10-IN-1 is a PARP inhibitor that inhibits ARTD8/PARP14 and has anticancer and antitumour activity for the study of prostate cancer.</p>Formule :C12H12N2O4Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :248.23Gartisertib
CAS :<p>Gartisertib (VX-803) is an ATR inhibitor with anti-tumor activity, inhibiting the anti-proliferative effects induced in ccRCC cells.</p>Formule :C25H29F2N9O3Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :541.55Daniquidone
CAS :<p>Daniquidone (Batracylin) is a potent dual inhibitor of DNA topoisomerase I and DNA topoisomerase II with cytotoxic and antiproliferative activity for neoplasms</p>Formule :C15H11N3ODegré de pureté :98.39% - 99.52%Couleur et forme :SolidMasse moléculaire :249.2713-Oxo-9E,11E-octadecadienoic acid
CAS :<p>13-Oxo-9E,11E-octadecadienoic acid from tomato juice, an isomer of 9-oxo-ODA, activates PPARα and lowers triglycerides in diabetic mice.</p>Formule :C18H30O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :294.43Tetrahydrouridine
CAS :<p>Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.</p>Formule :C9H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.23DC_517
CAS :<p>DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM).</p>Formule :C33H35N3O2Couleur et forme :SolidMasse moléculaire :505.65Seladelpar Lysine dihydrate
CAS :<p>Seladelpar lysine, a selective PPAR-δ agonist, is used for the therapy of Homozygous Familial Hypercholesterolemia (HoFH).</p>Formule :C27H41F3N2O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :626.68ATR-IN-15
CAS :<p>ATR-IN-15, an ATR kinase inhibitor, has an IC50 of 8 nM and also targets LoVo cells, DNA-PK, and PI3K with higher IC50 values.</p>Formule :C19H22N8OCouleur et forme :SolidMasse moléculaire :378.43Saroglitazar
CAS :<p>Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.</p>Formule :C25H29NO4SDegré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :439.57ARH-049020
CAS :<p>ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.</p>Formule :C24H31NO6Degré de pureté :97.19% - 99.82%Couleur et forme :SolidMasse moléculaire :429.51Daltroban
CAS :<p>Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.</p>Formule :C16H16ClNO4SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :353.82XR-5000
CAS :<p>XR-5000 is a DNA topoisomerase I and II inhibitor.</p>Formule :C18H19N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :293.366-Methyl-5-azacytidine
CAS :<p>6-Methyl-5-azacytidine is a potent DNMT inhibitor.</p>Formule :C9H14N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :258.23NS-220
CAS :<p>NS-220 selectively activates PPAR-alpha, reducing triglycerides and glucose in KK-Ay mice, also altering lipoproteins.</p>Formule :C21H27NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :373.44L-796449
CAS :<p>L-796449 is an agonist of PPAR-gamma.</p>Formule :C28H27ClO4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.03RG-12525
CAS :<p>RG-12525（NID 525） is an orally available, selective and competitive leukotriene D (LTD) antagonist that inhibits LTC4, LTD4 and LTE4-induced contraction of</p>Formule :C25H21N5O2Degré de pureté :95.49%Couleur et forme :SolidMasse moléculaire :423.47DB-959 (free base)
CAS :<p>DB-959 is a potential agonist of PPAR.</p>Formule :C25H27NO5Couleur et forme :SolidMasse moléculaire :421.49Mitobronitol
CAS :<p>Mitobronitol, a brominated mannitol analog, is an alkylating anticancer drug that aids in reducing allogeneic bone marrow transplant risks.</p>Formule :C6H12Br2O4Couleur et forme :SolidMasse moléculaire :307.97NC190 sodium
CAS :<p>NC190 inhibits topoisomerase II, halts FM3A cell growth (IC50: 0.019 μg/ml in 48h), and suppresses DNA synthesis by 90% at 0.1 μg/ml.</p>Formule :C23H22N4NaO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :457.442Naveglitazar
CAS :<p>Naveglitazar (LY 519818, LY 9818), a PPAR modulator in phase II trials for type 2 diabetes.</p>Formule :C25H26O6Couleur et forme :SolidMasse moléculaire :422.47Ertiprotafib
CAS :<p>Ertiprotafib (PTP 112), a PTP1B and IKK-β inhibitor, is a novel insulin sensitizer for the study of type 2 diabetes and breast cancer.</p>Formule :C31H27BrO3SDegré de pureté :98.70%Couleur et forme :SolidMasse moléculaire :559.51Sirt2-IN-1
CAS :<p>Sirt2-IN-1 is an inhibitor of sirtuin 2 (IC50 = 163 nM).</p>Formule :C28H27N7O2S2Degré de pureté :99.57% - 99.84%Couleur et forme :SolidMasse moléculaire :557.69Topoisomerase I inhibitor 7
CAS :<p>Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I.</p>Formule :C22H19N3O5Couleur et forme :SolidMasse moléculaire :405.4LG100754
CAS :<p>LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.</p>Formule :C26H36O3Couleur et forme :SolidMasse moléculaire :396.569-Hydroxyellipticine hydrochloride
CAS :<p>9-Hydroxyellipticine hydrochloride is an inhibitor of Topo II and RyR, exhibits antitumor and antileukemic activity, and inhibits carrageenan gum-induced edema.</p>Formule :C17H15ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :298.77GW 9578
CAS :<p>GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.</p>Formule :C26H34F2N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :492.62Chiglitazar
CAS :<p>Chiglitazar is a PPAR α/γ/δ agonist and insulin sensitizer used in the treatment of type 2 diabetes mellitus , anti-inflammatory and anti-fibrotic.</p>Formule :C36H29FN2O4Couleur et forme :SolidMasse moléculaire :572.63Topoisomerase IV inhibitor 2
CAS :<p>Compound 5d, a potent TOPO IV inhibitor (IC50: 0.35 μM), also inhibits DNA gyrase (IC50: 0.55 μM) and has antibacterial activity.</p>Formule :C33H30FN7O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :671.7ATR-IN-23
CAS :<p>ATR-IN-23 (Compound 34), a potent and selective ATR inhibitor, exhibits an IC50 of 1.5 nM, has demonstrated antiproliferative effects on LoVo cells, and induces</p>Formule :C20H22N6O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.56HDAC ligand-1
CAS :<p>HDAC ligand-1 is a synthetic precursor utilized in the production of PROTAC-based HDAC degraders [1].</p>Formule :C7H8N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :136.15HDAC-IN-58
CAS :<p>HDAC-IN-58, a selective HDAC6 inhibitor, exhibits potent inhibitory activity with an IC50 of 2.06 nM, rendering it suitable for research into chronic</p>Formule :C16H13ClF2N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.81PB131
CAS :<p>PB131, a selective and brain-permeable HDAC6 inhibitor, exhibits high binding affinity (IC50: 1.8 nM) and potent anti-inflammatory activity, making it suitable</p>Formule :C16H16FN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :301.32Topoisomerase IV inhibitor 1
CAS :<p>Compound 7d: Inhibits TOPO IV (IC50: 0.23 μM), DNA gyrase (IC50: 0.43 μM), antibacterial against S. aureus (MIC: 0.972 μM), E. coli (MIC: 0.608 μM).</p>Formule :C34H32FN7O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :685.72Topoisomerase II inhibitor 16
CAS :<p>Topoisomerase II Inhibitor 16 (compound CT3) is a selective, orally bioavailable, and irreversible inhibitor of trypanosomal topoisomerase II, possessing the</p>Formule :C19H12F4N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.33Guadecitabine sodium
CAS :<p>Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .</p>Formule :C18H24N9NaO10PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :580.407HDAC-IN-5
CAS :<p>HDAC-IN-5 is a histone deacetylase (HDAC) inhibitor.</p>Formule :C26H24F3N5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.56PluriSIn #2
CAS :<p>PluriSIn #2 is a selective topoisomerase II α (topo2α) transcription inhibitor exhibiting cytotoxicity towards undifferentiated, leukaemogenic hPSCs.</p>Formule :C11H8FN3O3Degré de pureté :98% - 99.79%Couleur et forme :SolidMasse moléculaire :249.2CCT128930
CAS :<p>'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'</p>Formule :C18H20ClN5Degré de pureté :99.07% - 99.18%Couleur et forme :SolidMasse moléculaire :341.84HWL-088
CAS :<p>HWL-088 is a potent free fatty acid receptor 1 (FFA1/GPR40) agonist. HWL-088 significantly improves glucose tolerance in normal and diabetic models.</p>Formule :C22H19FO4Couleur et forme :SolidMasse moléculaire :366.38Topoisomerase IIα-IN-2
CAS :<p>Topoisomerase IIα-IN-2 (compound 5) is a DNA-binding ligands and a potent inhibitor of the topoisomerase TopoIIα.</p>Formule :C22H20N4O5Couleur et forme :SolidMasse moléculaire :420.42NHC-triphosphate
CAS :<p>NHC-triphosphate is a weak alternative substrate for the viral polymerase and changes the mobility of the product in polyacrylamide electrophoresis gels.</p>Formule :C9H16N3O15P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :499.16PPARα/δ agonist 1
CAS :<p>PPARα/δ agonist 1 is a potent PPARα/PPARδ dual agonist with EC50 values of 7.0 nM for PPARα and 8.4 nM for PPARδ.</p>Formule :C22H22F3N3O5Couleur et forme :SolidMasse moléculaire :465.42BMS-711939
CAS :<p>BMS-711939: Potent PPARα agonist, EC50=4 nM, shown effective and safe in preclinical trials.</p>Formule :C22H20ClFN2O6Couleur et forme :SolidMasse moléculaire :462.86Mipicoledine
CAS :<p>DM-CHOC-PEN is a DNA alkylation agent that may be used to treat brain cancer.</p>Formule :C35H48Cl5NO4Couleur et forme :SolidMasse moléculaire :724.02DNA-PK-IN-5
CAS :<p>DNA-PK-IN-5: potent DNA-PK inhibitor, reduces tumor repair, induces apoptosis, enhances radiotherapy, overcomes resistance.</p>Formule :C21H22N8O2Couleur et forme :SolidMasse moléculaire :418.45NK314
CAS :<p>NK314, a benzo[c]phenanthridine, inhibits topoisomerase II causing DNA breaks within 1h, even without proteinase K digestion.</p>Formule :C22H20ClNO4Couleur et forme :SolidMasse moléculaire :397.853,6-Diamino-9(10H)-acridone
CAS :<p>3,6-Diamino-9(10H)-acridone is an inhibitor of topoisomerase [1].</p>Formule :C13H11N3OCouleur et forme :SolidMasse moléculaire :225.25DSO-5a
CAS :<p>DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.</p>Formule :C23H24N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.45Resminostat
CAS :<p>Resminostat (4SC-201) is an orally bioavailable inhibitor of histone deacetylases (HDACs) with potential antineoplastic activity.</p>Formule :C16H19N3O4SDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :349.4Pparδ agonist 7
CAS :<p>Pparδ agonist 7 is a potent agonist of Pparδ.</p>Formule :C25H25NO5Couleur et forme :SolidMasse moléculaire :419.47LT175
CAS :<p>LT175 is a dual PPARα/γ partial agonist, insulin sensitizer, orally active, with lower adipogeny (EC50: hPPARα 0.22μm, mPPARα 0.26μm, hPPARγ 0.48μm).</p>Formule :C21H18O3Couleur et forme :SolidMasse moléculaire :318.37Topoisomerase I inhibitor 6
CAS :<p>Topoisomerase I inhibitor 6 traps DNA-Top1 complex, shows low non-cancer cell cytotoxicity, and has research value.</p>Formule :C23H21N7OCouleur et forme :SolidMasse moléculaire :411.46Sabarubicin
CAS :<p>Sabarubicin: a doxorubicin analogue with potent antitumor effects; superior in DNA fragmentation and topoisomerase II poisoning.</p>Formule :C32H37NO13Couleur et forme :SolidMasse moléculaire :643.64PR-104
CAS :<p>PR-104: hypoxia-activated DNA cross-linker, pre-prodrug for nitrogen mustard, converts to PR-104A in tumors.</p>Formule :C14H20BrN4O12PSCouleur et forme :SolidMasse moléculaire :579.27Cas9-IN-2
CAS :<p>Cas9-IN-2, an apo-Cas9 binder, inhibits Cas9 (IC50=246 μM), blocking Cas9:gRNA formation, regulating Cas9 function.</p>Formule :C21H27N5O4S2Couleur et forme :SolidMasse moléculaire :477.6GW409544
CAS :<p>GW409544 is an agonist of PPAR-alpha and PPAR-gamma.</p>Formule :C31H30N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.58Dihydro-5-azacytidine acetate
CAS :<p>Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1</p>Formule :C10H18N4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.27CP-67015
CAS :<p>CP 67015 has an inhibitory effect on the function of topoisomerase, and is a direct mutagen in mammalian cells, which has effects on gene and chromosome levels.</p>Formule :C17H12F2N2O3Couleur et forme :SolidMasse moléculaire :330.29TZD18
CAS :<p>TZD18, a novel PPAR alpha/gamma dual agonist, inhibits cell growth and induces apoptosis in human glioblastoma T98G cells.</p>Formule :C27H27NO5SCouleur et forme :SolidMasse moléculaire :477.57Topoisomerase II inhibitor 8
CAS :<p>Compound 22 is a potent topoisomerase II inhibitor (IC50=0.52μM), with strong anti-proliferative effects, arresting cells at G2/M.</p>Formule :C14H8N4O3SCouleur et forme :SolidMasse moléculaire :312.3DB-959 (salt)
CAS :<p>DB-959, a PPAR agonist, is used potentially for the treatment of Alzheimer's disease.</p>Formule :C25H27NNaO5Couleur et forme :SolidMasse moléculaire :444.483MD001
CAS :<p>MD001 is a PPARα/γ agonist, binds at Kds 9.55/0.14 μM, boosts transcription, and regulates glucose, lipid levels in diabetic mice.</p>Formule :C25H18O5Couleur et forme :SolidMasse moléculaire :398.41NCI172112
CAS :<p>NCI172112 is is used to develop antitumor agents effective against CNS tumors.</p>Formule :C14H23Cl2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.26DNMT3A-IN-1
CAS :<p>DNMT3A-IN-1 is a potent, selective DNMT3A inhibitor with KI 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).</p>Formule :C30H38N6O4Couleur et forme :SolidMasse moléculaire :546.6617(S)-HDHA
CAS :<p>17(S)-HDHA: A DHA derivative in human blood/cells and mouse brain; leads to 17(S)-resolvins; inhibits IL-1β and leukocyte trafficking.</p>Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.49DNA-PK-IN-7
CAS :<p>DNA-PK-IN-7 is a potent DNA-PK inhibitor (IC50= 1 nM) (WO2021104277A1, compound 5).</p>Formule :C19H21N9O2Couleur et forme :SolidMasse moléculaire :407.43PPARγ agonist 6
CAS :<p>PPARγ agonist 6 (Compound 12) is a potent agonist of selective PPARγ. PPARγ agonist 6 has potential for cancer disease research.</p>Formule :C27H26N2O4Couleur et forme :SolidMasse moléculaire :442.51CP-67804
CAS :<p>CP 67804 enhances topoisomerase II-mediated DNA cleaving.</p>Formule :C18H13F2NO4Couleur et forme :SolidMasse moléculaire :345.3PPARγ agonist 5
CAS :<p>PPARγ agonist 5 is a selective and potent PPARγ agonist that has shown research potential for cancer disease.</p>Formule :C33H31N5OCouleur et forme :SolidMasse moléculaire :513.63ICRF-196
CAS :<p>ICRF-196 is a Topoisomerase II Inhibitor and antineoplastic agent.</p>Formule :C12H18N4O4Couleur et forme :SolidMasse moléculaire :282.3SKLB-197
CAS :<p>SKLB-197 targets ATR, inhibiting it at 0.013 μM, and is inactive on 402 other kinases, showing potent antitumor effects on ATM-deficient tumors.</p>Formule :C25H24N6OCouleur et forme :SolidMasse moléculaire :424.5G3335
CAS :<p>H-Trp-Glu-OH: Selective, reversible PPARγ modulator; cell-permeable; Kd ~8μM; potential diabetes lead.</p>Formule :C16H19N3O5Couleur et forme :SolidMasse moléculaire :333.34DNA-PK-IN-4
CAS :<p>DNA-PK-IN-4, an imidazolinone, targets DNA-PKcs to hinder tumor DNA repair and induce apoptosis, showing cancer research potential.</p>Formule :C20H24N6O3Couleur et forme :SolidMasse moléculaire :396.44AM-3102
CAS :<p>AM-3102: An OEA analog; boosts PPARα, delays eating, resists hydrolysis, mimics OEA potency, and weakly binds CB1/CB2.</p>Formule :C21H41NO2Couleur et forme :SolidMasse moléculaire :339.56BNS-22
CAS :<p>BNS-22 is a DNA topoisomerase II (Topo II) inhibitor, induces mitotic abnormalities and exhibits antiproliferative activity against human cancer cells.</p>Formule :C24H25NO5Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :407.46NSC-311068
CAS :<p>NSC-311068: A selective TET1 inhibitor, reducing 5hmC and AML cell viability with high TET1.</p>Formule :C10H6N4O4SCouleur et forme :SolidMasse moléculaire :278.24DRF 2519
CAS :<p>DRF 2519 is an activator of PPAR-alpha and PPAR-gamma.</p>Formule :C20H18N2O5SCouleur et forme :SolidMasse moléculaire :398.43Ranimustine
CAS :<p>Ranimustine (MCNU) can be used for polycythemia vera and chronic myelogenous leukemia research, which is a nitrosourea alkylating agent [1] [3] [4].</p>Formule :C10H18ClN3O7Couleur et forme :SolidMasse moléculaire :327.72PPARδ agonist 8
CAS :<p>Pparδ agonist 8 is a potent agonist of Pparδ. Pparδ agonist 8 has potential for the study of nonalcoholic fatty liver disease (NAFLD).</p>Formule :C25H29NO5Couleur et forme :SolidMasse moléculaire :423.5AA-CW236
CAS :<p>AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).</p>Formule :C17H16ClF3N4O2Couleur et forme :SolidMasse moléculaire :400.78CAY10514
CAS :<p>CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPARα and PPARγ with EC50 values of 0.173 and 0.642 μM, respectively.</p>Formule :C20H28O4Couleur et forme :SolidMasse moléculaire :332.43Ceralasertib formate
CAS :<p>Ceralasertib: an oral ATR kinase inhibitor that blocks CHK1 phosphorylation, disrupts DNA repair, and triggers tumor cell apoptosis.</p>Formule :C21H26N6O4SCouleur et forme :SolidMasse moléculaire :458.54Exatecan mesylate dihydrate
CAS :<p>Exatecan mesylate dihydrate (DX-8951), a DNA topoisomerase I inhibitor, exhibits an IC50 of 2.2 μM (0.975 μg/mL) and is utilized in cancer research [1] [2] [3].</p>Formule :C25H30FN3O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :567.58WEHI-150
CAS :<p>WEHI-150, a mitoxantrone analog, cross-links DNA, targets methylated CpG, halts transcription, and avoids guanine N-2 interaction.</p>Formule :C22H30N6O4Couleur et forme :SolidMasse moléculaire :442.51Topoisomerase I inhibitor 4
CAS :<p>Topoisomerase I inhibitor 4 targets cancer cells like HepG2, A549, MCF-7, HeLa with low IC50, promising for research.</p>Formule :C23H19FN4OCouleur et forme :SolidMasse moléculaire :386.42MLR24
CAS :<p>MLR24 is a selective modulator of PPARγ that acts by displaying robust anti-diabetic activity.</p>Formule :C28H24F3NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.49Anticancer agent 75
CAS :<p>Anticancer agent 75: potent, selective, less toxic to kidneys than Doxorubicin by 35x, with antiplasmodial properties.</p>Formule :C22H24N2OCouleur et forme :SolidMasse moléculaire :332.44Piroxantrone
CAS :<p>Piroxantrone (CI942; PD111815) is an anthrapyrazole antibiotic that disrupts DNA replication and repair, with limited cardiotoxicity and antineoplastic range.</p>Formule :C21H25N5O4Couleur et forme :SolidMasse moléculaire :411.45ATR-IN-16
CAS :<p>ATR-IN-16 (compound 46) is an ATR kinase inhibitor with potent anticancer effects in LoVo cells, IC50 of 410 nM.</p>Formule :C19H25N7OCouleur et forme :SolidMasse moléculaire :367.45DNA-PK-IN-3
CAS :<p>DNA-PK-IN-3 is a potent DNA-PK inhibitor, enhancing radio/chemotherapy and reducing tumors with limited side effects.</p>Formule :C19H19N9OCouleur et forme :SolidMasse moléculaire :389.415-Aza-4'-thio-2'-deoxycytidine
CAS :<p>5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].</p>Formule :C8H12N4O3SCouleur et forme :SolidMasse moléculaire :244.27DNA-PK-IN-1
CAS :<p>DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-PK-IN-1 has potential for cancer disease research.</p>Formule :C23H26N8O2Couleur et forme :SolidMasse moléculaire :446.5KRP-297
CAS :<p>KRP297 is a PPAR agonist potentially for the treatment of type 2 diabetes and dyslipidemia.</p>Formule :C20H17F3N2O4SCouleur et forme :SolidMasse moléculaire :438.42SW155246
CAS :<p>SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).</p>Formule :C16H11ClN2O5SDegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :378.79MPT0G211
CAS :<p>MPT0G211: oral HDAC6 inhibitor with IC50=0.291 nM, 1000x selectivity, neuroprotective, anti-metastatic, crosses blood-brain barrier for Alzheimer's.</p>Formule :C17H15N3O2Degré de pureté :98% - 99.88%Couleur et forme :SolidMasse moléculaire :293.32ICRF-193
CAS :<p>ICRF-193 is a DNA topoisomerase II inhibitor.</p>Formule :C12H18N4O4Couleur et forme :SolidMasse moléculaire :282.3CM-579
CAS :<p>CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.</p>Formule :C29H40N4O3Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :492.65GW2433
CAS :<p>GW2433 is an agonist of PPAR receptor.</p>Formule :C28H28Cl3FN2O4Couleur et forme :SolidMasse moléculaire :581.89XR-11576
CAS :<p>XR-11576 is a DNA topoisomerase I and II inhibitor for the treatment of solid tumors.</p>Formule :C23H24N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :388.46PPARγ agonist 3
CAS :<p>PPARγ agonist 3, also known as Compound 18a, is a potent and selective agonist of PPARγ.</p>Formule :C24H23N3OCouleur et forme :SolidMasse moléculaire :369.46Exifone
CAS :<p>Exifone (NSC-680919) is a mixed, nonessential activator of HDAC1 that is capable of binding to both free and substrate-bound enzyme, resulting in an increased</p>Formule :C13H10O7Degré de pureté :99.77% - 99.95%Couleur et forme :Yellow SolidMasse moléculaire :278.21Cas9-IN-3
CAS :<p>Cas9-IN-3 is a potent inhibitor of Cas9 with IC50 of 28 μM. CRISPR/Cas systems have revolutionized gene editing in several species [1].</p>Formule :C19H21NOCouleur et forme :SolidMasse moléculaire :279.38Aldoxorubicin
CAS :<p>Aldoxorubicin, an albumin-binding prodrug of Doxorubicin, exhibits potent antitumor effects in cancer lines and mouse models.</p>Formule :C37H42N4O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :750.75RSC-133
CAS :<p>promotes the reprogramming of human somatic cells to pluripotent stem cells</p>Formule :C18H15N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :305.33SIRT2-IN-9
CAS :<p>SIRT2-IN-9: selective SIRT2 inhibitor; IC50=1.3μM; halts MCF-7 cell growth; for cancer study.</p>Formule :C21H22N6OS2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :438.57Topoisomerase II inhibitor 4
CAS :<p>Compound E17, a topoisomerase II inhibitor, halts cell cycle at G2/M, possesses anticancer properties and cytotoxic effects.</p>Formule :C25H25N5O4Couleur et forme :SolidMasse moléculaire :459.5PPARγ agonist 4
CAS :<p>PPARγ agonist 4 (Compound 18b), a potent and selective PPARγ agonist, demonstrates antitumor efficacy only when used in conjunction with Imatinib.</p>Formule :C24H22FN3OCouleur et forme :SolidMasse moléculaire :387.45ITF3756
CAS :<p>ITF3756 is a selective HDAC6 inhibitor.</p>Formule :C13H11N5O2SDegré de pureté :97.74%Couleur et forme :SolidMasse moléculaire :301.32CEP-9722
CAS :<p>CEP-9722 is a PARP-1 and PARP-2 inhibitor with anticancer activity and is used in the study of ovarian cancer.</p>Formule :C24H26N4O3Degré de pureté :98.38% - 98.56%Couleur et forme :SolidMasse moléculaire :418.49HDAC8-IN-20a
CAS :<p>HDAC8-IN-20a (HDAC8 inhibitor-20a) is a potent and selective HDAC8 inhibitor with an IC50 of 27 nM.</p>Formule :C15H15NO4Degré de pureté :98.24% - 99.22%Couleur et forme :SolidMasse moléculaire :273.28Tenifatecan
CAS :<p>Tenifatecan (SN2310) is a highly lipophilic preparation of 7-ethyl-10-hydroxycamptothecin (SN) with potential antitumor activity.</p>Formule :C55H72N2O9Degré de pureté :99.58% - 99.82%Couleur et forme :SolidMasse moléculaire :905.17AGI-24512
CAS :<p>AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in</p>Formule :C24H24N4O2Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :400.47EB-47
CAS :<p>EB-47 imitates NAD+, spans nicotinamide to adenosine sites, inhibits PARP-1 (IC50: 45 nM) and is less effective on ARTD5 (IC50: 410 nM).</p>Formule :C24H27N9O6Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :537.53BRD 9757
CAS :<p>BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) is a selective inhibitor of HDAC6 (IC50 = 30 nM).</p>Formule :C6H9NO2Degré de pureté :98.39% - 99.87%Couleur et forme :SolidMasse moléculaire :127.14Procainamide
CAS :<p>Procainamide: DNMT1 inhibitor, Class 1A antiarrhythmic, promising for cancer and arrhythmia research.</p>Formule :C13H21N3ODegré de pureté :99.92% - 99.92%Couleur et forme :SolidMasse moléculaire :235.33(R)-(-)-Rolipram
CAS :<p>(R)-(-)-Rolipram ((-)-Rolipram) is an R-enantiomer of Rolipram which is a PDE4 inhibitor.</p>Formule :C16H21NO3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :275.34SS-208
CAS :<p>SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.</p>Formule :C13H11Cl2N3O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :344.15Givinostat hydrochloride
CAS :<p>Givinostat HCl (ITF2357 HCl) inhibits HDAC1/3 (IC50: 198/157 nM) with anti-inflammatory, anti-angiogenic, and antineoplastic properties.</p>Formule :C24H28ClN3O4Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :457.95DN-1289
<p>DN-1289: oral, BBB-penetrating, selectively inhibits DLK (IC50=17nM) & LZK (IC50=40nM), blocks p-c-Jun in mouse optic nerve crush.</p>Formule :C18H19F4N7O2Degré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :441.38SIRT6-IN-5
CAS :<p>SIRT6-IN-5: potent, selective SIRT6 inhibitor; IC50=34 μM; immunosuppressive, enhances chemo, boosts H3K9 acetylation, glucose uptake, curbs T-cell growth.</p>Formule :C19H14N2O6Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :366.32Dehydroepiandrosterone sulfate
CAS :<p>Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.</p>Formule :C19H28O5SDegré de pureté :97.18%Couleur et forme :SolidMasse moléculaire :368.49SIRT5 inhibitor 1
CAS :<p>SIRT5 inhibitor 1 targets human Sirtuin 5 deacylase, with an IC50 of 0.11 μM, linked to aging diseases.</p>Formule :C31H39FN6O6S2Degré de pureté :97.8%Couleur et forme :SolidMasse moléculaire :674.81ACY-1083
CAS :<p>ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy.</p>Formule :C17H18F2N4O2Degré de pureté :99.19% - 99.43%Couleur et forme :SolidMasse moléculaire :348.35BRD2492
CAS :<p>BRD2492 is an HDAC1 and HDAC2 inhibitor with antiproliferative activity, inhibits HDAC1/2 and induces apoptosis.</p>Formule :C20H18N4O2Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :346.38BTB09089
CAS :<p>BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production</p>Formule :C14H12Cl2N4OS2Degré de pureté :99.78%Couleur et forme :SoildMasse moléculaire :387.31BRD6688
CAS :<p>BRD6688 is a selective HDAC2 inhibitor that acts by enhancing the learning and memory processes</p>Formule :C16H18N4ODegré de pureté :97.53%Couleur et forme :SolidMasse moléculaire :282.34NSC16168
CAS :<p>NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.</p>Formule :C17H15NO9S3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :473.5Cedazuridine
CAS :<p>Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.</p>Formule :C9H14F2N2O5Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :268.21OUL232
CAS :<p>OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.</p>Formule :C10H10N4O2SDegré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :250.28PARP10-IN-2
CAS :<p>PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and</p>Formule :C14H10N2O2Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :238.24Chloroquinoxaline sulfonamide
CAS :<p>Chloroquinoxaline sulfonamide (Chloroquinoxaline) is an organic micropollutant with antimicrobial activity.</p>Formule :C14H11ClN4O2SDegré de pureté :99.79% - 99.89%Couleur et forme :SolidMasse moléculaire :334.78L82
CAS :<p>L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.</p>Formule :C11H8ClN5O4Degré de pureté :97.45% - 98.91%Couleur et forme :SolidMasse moléculaire :309.67Bobcat339 hydrochloride
CAS :<p>Bobcat339 hydrochloride is a 10 11 translocation (TET) dioxygenase inhibitor that inhibits both TET1 and TET2.</p>Formule :C16H13Cl2N3ODegré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :334.2Suksdorfin
CAS :<p>Suksdorfin has hypoglycemic effects and activates PPARγ, which promotes insulin-dependent glucose uptake by adipocytes and can be used to study obesity .</p>Formule :C21H24O7Degré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :388.41BRD4097
CAS :<p>BRD4097, a negative control in the HDAC1/2/3/8 assay, is a selective histone deacetylase (HDAC3) inhibitor that can be used to protect b-cells and improve</p>Formule :C16H17N3O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :283.33Linotroban
CAS :<p>Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.</p>Formule :C14H15NO5S2Degré de pureté :97.95% - >99.99%Couleur et forme :SolidMasse moléculaire :341.4ACY-957
CAS :<p>ACY-957: Oral HDAC1/2 inhibitor (IC50: HDAC1=7nM, HDAC2=18nM, HDAC3=1300nM); inactive on HDAC4/5/6/7/8/9.</p>Formule :C24H23N5OSDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :429.54ISX-1
CAS :<p>ISX-1 inhibits adipogenesis and promotes osteoblastogenesis. ISX-1 can be used in studies about osteoporosis and osteopenia.</p>Formule :C14H14N4O2SDegré de pureté :98.7%Couleur et forme :SolidMasse moléculaire :302.35Vutiglabridin
CAS :<p>Vutiglabridin (HSG4112), a PON2 modulator, is more stable and aids weight loss than Glabridin. In phase 2 trials for obesity, shows promise for PD therapy.</p>Formule :C22H26O4Degré de pureté :98.47% - 99.07%Couleur et forme :SolidMasse moléculaire :354.44Miriplatin hydrate
CAS :<p>Miriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC).</p>Formule :C34H70N2O5PtDegré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :782.01Alalevonadifloxacin
CAS :<p>Alalevonadifloxacin is a DNA gyrase and DNA topoisomerase inhibitor and a novel antibacterial compound of the quinolone class targeting MRSa.</p>Formule :C23H30FN3O8SDegré de pureté :99.75% - 99.82%Couleur et forme :SoildMasse moléculaire :527.56Dazmegrel
CAS :<p>Dazmegrel (UK 38,485) is a thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.</p>Formule :C16H17N3O2Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :283.33Pegamotecan
CAS :<p>Pegamotecan (PEG-camptothecin) is a topoisomerase I (TOP1) inhibitor with anticancer activity, and it is used in the treatment of esophageal, non-small cell</p>Formule :C52H48N6O14Degré de pureté :96.40% - 97.83%Couleur et forme :SolidMasse moléculaire :980.984Ac-Exatecan
CAS :<p>Ac-Exatecan is acetylation-modified Exatecan.Exatecan (DX-8951) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 μM and antitumor activity.</p>Formule :C26H24FN3O5Degré de pureté :97.09%Couleur et forme :SolidMasse moléculaire :477.48HDAC6-IN-8
CAS :<p>Compound 12C, with altered cap groups, shows wide-range enzyme inhibition; 9m and 9q target HDAC6 specifically.</p>Formule :C23H17BrFN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.32CM-579 trihydrochloride (1846570-40-8 free base)
<p>CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide</p>Formule :C29H43Cl3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :602.04DY-46-2
CAS :<p>DY-46-2 is a DNMT3A inhibitor (IC50: 0.39 ± 0.23 μM) with anticancer activity and is used in cancer and tumor research.</p>Formule :C19H22N6O5SDegré de pureté :99.12% - 99.12%Couleur et forme :SolidMasse moléculaire :446.48Pradofloxacin
CAS :<p>Pradofloxacin is a fluoroquinolone antibioticthat exerts its bactericidal effect by inhibiting bacterial DNA gyrase and topoisomerase IV.</p>Formule :C21H21FN4O3Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :396.41SR 2595
CAS :<p>SR2595 is an inverse agonist of nuclear receptor PPARγ with an IC 50 of 30 nM [1].</p>Formule :C37H38N2O3Couleur et forme :SolidMasse moléculaire :558.71Trovafloxacin mesylate
CAS :<p>Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).</p>Formule :C21H19F3N4O6SDegré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :512.46DNA-PK-IN-10
CAS :<p>DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell lung cancer [1].</p>Formule :C25H28N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.53XY-4
CAS :<p>XY-4, a derivative of 1-palmitoyl lysophosphatidic acid (1-palmitoyl LPA094) and an agonist of peroxisome proliferator-activated receptor γ (PPARγ), effectively</p>Formule :C19H37F2O6PCouleur et forme :SolidMasse moléculaire :430.46NT160
CAS :<p>NT160 is a fluorinated radioactive compound, a potent class IIa histone deacetylase (HDAC) inhibitor, used in the study of neurological diseases.</p>Formule :C21H21F3N4O2Degré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :418.41Antipsychotic agent 54
CAS :<p>Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM).</p>Formule :C21H23FN2O4Degré de pureté :98.10%Couleur et forme :SolidMasse moléculaire :386.42Sipoglitazar
CAS :<p>Sipoglitazar, a PPARγ agonist, is used potentially for the treatment of diabetes.</p>Formule :C25H25N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :463.55Sirtuin modulator 1
CAS :<p>Sirtuin modulator 1 (SRT3025 Hydrochloride) is a modulator of SIRT1 with EC1.5 of < 1 μM.</p>Formule :C31H32ClN5O2S2Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :606.2BO 2367
CAS :<p>BO 2367, a topoisomerase inhibitor, is used to suppress the growth of tumor .</p>Formule :C21H22ClF2N3O3Couleur et forme :SolidMasse moléculaire :437.8710-Nitrolinoleic acid
CAS :<p>10-Nitrolinoleate, a nitration product of linoleate, modulates PPARγ, enhancing glucose uptake, and aids in muscle relaxation via NO/cGMP pathway.</p>Formule :C18H31NO4Couleur et forme :SolidMasse moléculaire :325.44HDAC/BET-IN-1
CAS :<p>HDAC/BET-IN-1 inhibits HDAC1 (IC50: 0.163 μM), HDAC6 (IC50: 0.067 μM), BRD4 (Ki: 0.076 μM), and fights leukemia.</p>Formule :C29H40N4O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :604.71Bocodepsin
CAS :<p>Bocodepsin (OKI-179) is a selective, orally active inhibitor of histone deacetylases (HDAC) with demonstrated antitumor efficacy.</p>Formule :C26H39N5O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :581.75ZL-2201
CAS :<p>ZL-2201 is a potent inhibitor of DNA-PK, demonstrating an IC50 value of 1 nM.</p>Formule :C20H25N9O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :503.54ATR-IN-29
CAS :<p>ATR-IN-29, a potent, orally active inhibitor of ATR kinase, exhibits an IC50 of 1 nM and demonstrates antiproliferative activity [1].</p>Formule :C19H22N8ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.43DS-6930
CAS :<p>DS-6930 is an potent and selective PPAR γ Agonists with EC50 of 41 nM.</p>Formule :C23H21N3O4Couleur et forme :SolidMasse moléculaire :403.43Bocodepsin hydrochloride
CAS :<p>Bocodepsin hydrochloride (OKI-179) is a selective HDAC inhibitor with antitumor properties, efficacious via oral administration.</p>Formule :C26H40ClN5O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :618.21U-46619
CAS :<p>U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (</p>Formule :C21H34O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.49PARP7-IN-16
CAS :<p>PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values of 0.94, 0.87, and 0.21 nM , respectively.</p>Formule :C25H26FN4NaO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :488.49HDAC8-IN-4
CAS :<p>HDAC8-IN-4 is a selective HDAC8 inhibitor, exhibiting inhibitory activity with IC50 values of 0.15 μM for HDAC8 and 12 μM for HDAC3 [1].</p>Formule :C17H14N2O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :342.44ATR-IN-22
CAS :<p>ATR-IN-22 (Compound 34), an orally active ATR inhibitor, exhibits potent anti-proliferative effects on MIAPaCa-2 cells with an IC50 value of less than 1 μM and</p>Formule :C25H31N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.56PPARγ agonist 7
CAS :<p>PPARγ agonist 7 (Compound 3a) is a highly potent and selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ).</p>Formule :C20H30O6Couleur et forme :SolidMasse moléculaire :366.45Topoisomerase I inhibitor 9
CAS :<p>Topoisomerase I Inhibitor 9 (compound 3d), a specific inhibitor of leishmanial topoisomerase IB, exhibits antileishmanial activity, demonstrating an IC50 value</p>Formule :C23H15Br2FN2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.19Duocarmycin analog-2
CAS :<p>Duocarmycin analog-2 is a potent DNA alkylating agent that exhibits antitumor effects and can be used in the synthesis of immunocouplers.</p>Formule :C29H23ClN4O3Couleur et forme :SolidMasse moléculaire :510.97Furegrelate sodium
CAS :<p>Furegrelate sodium (U-63557A) is an orally active thromboxane synthase inhibitor with an IC50 of 15 nM in platelets.</p>Formule :C15H10NNaO3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :275.23Tankyrase-IN-5
CAS :<p>Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2, with half-maximal inhibitory</p>Formule :C17H18N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :282.34TP0480066
CAS :<p>TP0480066 inhibits topoisomerase II, DNA gyrase (IC50=1.1nM), topo IV (IC50=62.89nM), effective against drug-resistant bacteria and N. gonorrhoeae.</p>Formule :C18H14FN3O5Couleur et forme :SolidMasse moléculaire :371.32Peliglitazar
CAS :<p>Peliglitazar is a activator of α/γ peroxisome proliferator-activated receptor.</p>Formule :C30H30N2O7Couleur et forme :SolidMasse moléculaire :530.57CAY10410
CAS :<p>CAY10410 is a PGD2/PGJ2 analog, modified for enhanced PPARγ activity and metabolic stability, non-toxic to SH-SY5Y cells at ≤25μM.</p>Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.45CM-675
CAS :<p>CM-675 is a dual inhibitor of phosphodiesterase 5 (PDE5) and class I histone deacetylases (IC50s: 114 nM and 673 nM for PDE5 and HDAC1) with the potential to</p>Formule :C31H32N6O3Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :536.629A1P9
CAS :<p>9A1P9, a multi-tail ionizable cationic phospholipid, facilitates membrane destabilization and is applicable for CRISPR-Cas9 gene editing in mice [1].</p>Formule :C27H58NO4PCouleur et forme :SolidMasse moléculaire :491.73KRP-101
CAS :<p>KRP-101, a PPARɑ agonist, is used potentially for the treatment of diabetes and hyperlipidaemia.</p>Formule :C26H26FNO5Couleur et forme :SolidMasse moléculaire :451.49ATR-IN-5
CAS :<p>ATR-IN-5 is a potent inhibitor of ATR, a member of the PIKK family of proteins involved in genome stability and DNA damage repair.</p>Formule :C27H32F3N9OCouleur et forme :SolidMasse moléculaire :555.6Topoisomerase IIα-IN-8
CAS :<p>Topoisomerase IIα-IN-8 (compound 15) serves as a modest inhibitor of human DNA topoisomerase IIα (htIIα), exhibiting an inhibitory concentration (IC50) of 462 ± 38.0 μM [1].</p>Formule :C15H15FN6OCouleur et forme :SolidMasse moléculaire :314.324KD-3010
CAS :<p>KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.</p>Formule :C30H33F3N2O8S2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :670.72(S)-Ceralasertib
CAS :<p>(S)-Ceralasertib: Potent, selective ATR inhibitor with strong preclinical physicochemical and PK profiles.</p>Formule :C20H24N6O2SCouleur et forme :SolidMasse moléculaire :412.51
