Endocrinologie/Hormones
Les inhibiteurs en endocrinologie/hormonaux sont des composés qui bloquent l'action des hormones ou interfèrent avec les voies de signalisation hormonales. Ces inhibiteurs sont essentiels pour étudier la régulation des systèmes endocriniens et pour développer des traitements pour les maladies liées aux hormones, telles que le diabète, les troubles de la thyroïde et les cancers hormonodépendants. En modulant l'activité hormonale, ces inhibiteurs peuvent aider à élucider les interactions complexes au sein du système endocrinien. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité en endocrinologie/hormonaux pour soutenir vos recherches en endocrinologie, pharmacologie et sciences médicales.
Sous-catégories appartenant à la catégorie "Endocrinologie/Hormones"
- Récepteur des androgènes(229 produits)
- Annexine A(16 produits)
- Aromatase(22 produits)
- Récepteur d'œstrogène/progestatif(59 produits)
- GPR(1 produits)
- Récepteur des glucocorticoïdes(166 produits)
- LHRH(2 produits)
- Récepteur opioïde(326 produits)
- Récepteur de prostaglandine(122 produits)
- RAAS(90 produits)
- Réductase(50 produits)
- Somatostatine(57 produits)
- Récepteur des hormones thyroïdiennes (THR)(32 produits)
- Récepteur de la vasopressine(48 produits)
Affichez 6 plus de sous-catégories
3373 produits trouvés pour "Endocrinologie/Hormones"
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DPP-4/GPR119 modulator 1
CAS :Orally active DPP-4 inhibitor/GPR119 agonist, Compound 22 lowers glucose, moderate hERG inhibition, IC50 4.9 µM, for diabetes research.Formule :C30H39ClN10O3Couleur et forme :SolidMasse moléculaire :623.15TCF199
TCF199, a conformational stabilizer, facilitates the interaction between the 14-3-3ζ/E R α peptide and the 14-3-3ζ/Chibby peptide, thereby stabilizing the 14-3-3/TAZ peptide complex. The dissociation constant (Kd) of TCF199 with the 14-3-3/TAZ complex is 122 μM.Formule :C17H24N2O2Couleur et forme :SolidMasse moléculaire :288.38Deltorphin acetate
Deltorphin acetate is a substance obtained from the skin secretions of a frog, Phyllomedusa bicolor and shows high selectivity and affinity for δ-opioidFormule :C46H66N10O12S2Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :1015.21Ref: TM-T20166L
1mg185,00€5mg415,00€10mg622,00€25mg1.119,00€50mg1.679,00€100mg2.520,00€200mg3.780,00€Bexirestrant
CAS :Bexirestrant is an orally active ER-α degrader commonly employed in the research of antiestrogen and antineoplastic therapies.Formule :C29H26F3NO2Couleur et forme :SolidMasse moléculaire :477.527Dehydroisoandrosterone 3-acetate
CAS :Dehydroisoandrosterone 3-acetate (Prasterone acetate) is a primary C19 steroid generated by the adrenal cortex.Formule :C21H30O3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :330.46Ganoderic acid Df
CAS :<p>Ganoderic acid Df, a lanostane triterpenoid from Ganoderma lucidum, inhibits aldose reductase with IC50 of 22.8 μM.</p>Formule :C30H44O7Couleur et forme :SolidMasse moléculaire :516.67Human PTHrP-(1-36)
CAS :Human PTHrP-(1-36) is a secreted form of parathyroid hormone-related protein that exhibits anticalciuric effects and promotes beta cell function andFormule :C191H305N59O52Masse moléculaire :4259.83Inocoterone acetate
CAS :Inocoterone acetate is a nonsteroidal antiandrogen that binds to the androgen receptor and possesses antiandrogenic activity in animal models.Formule :C18H26O3Couleur et forme :SolidMasse moléculaire :290.40Demoxytocin
CAS :Demoxytocin, oxytocin analog, enhances smooth muscle contraction by increasing calcium ion permeability. Used in labor research.Formule :C43H65N11O12S2Masse moléculaire :992.17PROTAC ER Degrader-12
PROTACER Degrader-12 (Compound 70) is an estrogen receptor PROTAC degrader with a degradation concentration (DC50) of less than 10 nM. It inhibits the proliferation of MCF-7 cells at a DC50 of under 10 nM and exhibits anticancer properties.Formule :C47H48F3N5O5Masse moléculaire :819.36075AM-5262
CAS :AM-5262 is a potent GPR40 Full Agonist with improved rat PK profile and general selectivity profile.Formule :C33H35FO4Couleur et forme :SolidMasse moléculaire :514.63ER degrader 4
CAS :ER degrader 4, a selective and orally active compound, effectively degrades estrogen receptors and exhibits anti-tumor activity [1].Formule :C26H19FO4SCouleur et forme :SolidMasse moléculaire :446.49Leumorphin, human
CAS :Leumorphin, human, is a potent agonist of the kappa opioid receptor (κ opioid receptor) and inhibits the contraction of the guinea pig ileum's myenteric plexus-Formule :C150H224N42O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3351.64Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.Formule :C42H55F3N8O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :888.93AH 7563
CAS :AH 7563 is structurally classified as an opioid compound with analgesic properties. In mice, its ED50 for pain relief was 15.3 mg/kg when administered orally in the Phenylquinone test, and 15.5 mg/kg when injected subcutaneously in the Hot plate test.Formule :C16H24N2OCouleur et forme :SolidMasse moléculaire :260.38β-S-ARCA triammonium
β-S-ARCA (triammonium) is an analog of the mRNA7-methylguanosine (m7G) cap structure, featuring a thio-phosphorylated segment. When bound to mRNA, β-S-ARCA (triammonium) extends the cellular half-life and enhances protein expression. This compound is utilized in research for mRNA-based cancer vaccines.Formule :C22H40N13O17P3SCouleur et forme :SolidMasse moléculaire :883.62K-Opioid receptor agonist-1
CAS :K-Opioid receptor agonist-1 (Compound 5a) acts as an agonist for the κ-Opioid receptor, exhibiting a K_i of 0.25 nM and an EC_50 of 2 nM. This compound is capable of crossing the blood-brain barrier (BBB), evidenced by brain/plasma ratios ranging from 0.50 to 0.65. Additionally, K-Opioid receptor agonist-1 demonstrates anti-inflammatory effects in dermatitis models induced by either Arachidonic acid or oxazolidinone.Formule :C22H29Cl2N3O3Masse moléculaire :454.39Antidiabetic agent 15
<p>Antidiabetic agent 15 (compound 1B15) acts as a dual inhibitor of AT1R and NEP, reducing oxidative stress and restoring mitochondrial membrane potential.</p>Formule :C26H23NO5Couleur et forme :SolidMasse moléculaire :429.15762OT antagonist 3 analog
OT antagonist 3 analog is an analog of OT antagonist 3.Formule :C20H18N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.4Nurr1 agonist 12
Nurr1 agonist 12 (Compound 37) acts as an agonist of the nuclear receptor-related protein 1 (Nurr1), enhancing its transcriptional activity with an EC50 of 0.06 μM. It stimulates human response elements NBRE, NurRE, and DR5 with EC50 values of 0.07 μM, 0.027 μM, and 0.014 μM, respectively. Additionally, Nurr1 agonist 12 induces the expression of neurotrophic genes regulated by Nurr1, such as tyrosine hydroxylase (TH), SOD1/2, BDNF, Sestrin 3, and BIRC5 (Survivin). The compound also demonstrates neuroprotective effects against neurotoxicity caused by Paraquat.Formule :C18H12ClN3OCouleur et forme :SolidMasse moléculaire :321.76U-48520
CAS :U-48520 is an agonist of the μ-opioid receptor (μ-opioid receptor) with an EC50 of 1561 nM.Formule :C16H23ClN2OCouleur et forme :SolidMasse moléculaire :294.82Bilaid C
CAS :Bilaid C: Tetrapeptide μ-opioid agonist from Penicillium (Ki=210 nM), inhibits cAMP (77% at 10 μM), induces Kir currents (EC50=4.2 μM).Formule :C28H38N4O6Masse moléculaire :526.62A 65317
CAS :A 65317 is a selective renin inhibitor that causes a blockade of the renin-angiotensin system.Formule :C38H58N6O9Couleur et forme :SolidMasse moléculaire :742.90D-Ala-Gly-Phe-Met-NH2 monoacetate
CAS :D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, serves as a potent agonist for the opiate δ-receptor [1].Formule :C21H33N5O6SMasse moléculaire :483.58PROTAC AR Degrader-10
PROTACAR Degrader-10 is a protein degrader targeting androgen receptors (AR) with a DC50 value of ≤100 nM, and can be used in prostate cancer research.6-Amino-5-bromoquinoxaline
CAS :Compound PDK0245, with CAS No. 50358-63-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0245 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C8H6BrN3Masse moléculaire :224.05Myrciacetin
CAS :Myrciacetin from Rhododendron inhibits rat aldose reductase with IC50 of 13 μM.Formule :C17H16O6Couleur et forme :SolidMasse moléculaire :316.309Epi-Cryptoacetalide
Epi-Cryptoacetalide is a useful organic compound for research related to life sciences and the catalog number is T126054.Formule :C18H22O3Couleur et forme :SolidMasse moléculaire :286.371[D-Ala2]-Met-Enkephalinamide
CAS :[D-Ala2]-Met-Enkephalinamide: potent opioid, reduces bile flow centrally, analgesic.Formule :C28H38N6O6SMasse moléculaire :586.7Trh-gly
CAS :TRH-glycine (TRH-gly) serves as a precursor to thyrotropin-releasing hormone (TRH), capable of inducing the release of thyrotropin (TSH) and prolactin [1].Formule :C18H24N6O6Masse moléculaire :420.42ODM-204
CAS :ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme(IC50s of 80 nM and 22 nM, respectively).Formule :C20H21F3N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.40MT-7716 hydrochloride
CAS :MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP)Formule :C27H29ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477(S,S)-J-113397
CAS :(S,S)-J-113397 is an isomer of J-113397 . J-113397 is an Opioid Receptor antagonist [1] .Formule :C24H37N3O2Couleur et forme :SolidMasse moléculaire :399.57THR-β agonist 8
CAS :THR-β agonist 8 (Compound 1) is an orally active agonist for both TRα and TRβ. It holds potential for research into thyroid hormone-related diseases.Formule :C19H12Cl2N4O4Couleur et forme :SolidMasse moléculaire :431.23ACTH (6-24) (human)
CAS :Adrenocorticotropic hormone (6-24) (ACTH (6-24) (human)) is a fragment of ACTH that acts as a competitive inhibitor of steroidogenesis prompted by full-lengthFormule :C111H175N35O21Masse moléculaire :2335.8Enkephalin-met, ala(2)-
CAS :Enkephalin-met, ala(2)- is a synthetic analog of methionine enkephalin.Formule :C28H37N5O7SMasse moléculaire :587.69NR-V04
CAS :NR-V04 is a PROTAC degrader targeting NR4A1.Formule :C62H87N5O11SCouleur et forme :SolidMasse moléculaire :1110.45(-)-9-Hydroxycorynantheidine
CAS :(-)-9-Hydroxycorynantheidine (9-O-Desmethyl mitragynine) is a demethylated analog of Mitragynine, functioning as a selective and partial agonist for the μ-opioid receptor (μ-opioid receptor). This compound inhibits electrically stimulated twitch contractions in the guinea pig ileum.Formule :C22H28N2O4Couleur et forme :SolidMasse moléculaire :384.47CJ-15208
CAS :<p>CJ-15208: κ-opioid antagonist, IC50: 47 nM kappa, 260 nM mu, 2600 nM delta, reverses asimadoline effects in rabbits (ED50 1.3 µM).</p>Formule :C34H35N5O4Couleur et forme :SolidMasse moléculaire :577.67Flucloronide
CAS :Flucloronide is a corticosteroid for topical use on the skin. It has anti-inflammatory properties.Formule :C24H29Cl2FO5Couleur et forme :SolidMasse moléculaire :487.39Human PTH-(1-31) amide
CAS :Human PTH-(1-31) amide, an analog of PTH, effectively stimulates phosphatidylcholine hydrolysis and promotes the release of adenylyl cyclase [1].Formule :C162H270N50O46S2Masse moléculaire :3718.31MOR agonist-4
MOR agonist-4 (2d), having an EC50 of 11 nM, is a G protein-biased agonist of the Kappa opioid receptor (KOR). This compound features a triazole-based, electron-withdrawing CF3 group and a bias factor of 38. MOR agonist-4 is utilized for antipruritic and analgesic applications.Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg
Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg is a fluorescent renin substrate based on the N-terminal tetrapeptide sequence of human angiotensinogen (hTDP).Formule :C129H179N37O24SMasse moléculaire :2662.36444GPR88 agonist 2
GPR88 agonist 2 (compound 53) serves as a potent, brain-penetrant agonist of GPR88, exhibiting an EC50 of 14 µM in the GPR88 cAMP functional assay [1].Couleur et forme :Odour SolidGalloylalbiflorin
CAS :Galloylalbiflorin, an AR antagonist with IC50 53.3μM, is sourced from Paeonia lactiflora roots, exhibiting anti-androgenic properties.Formule :C30H32O15Couleur et forme :SolidMasse moléculaire :632.57DuP 747 HCl
CAS :DuP 747 HCl is a selective kappa agonist with analgesic activity.DuP 747 consists of two conformations.Formule :C24H29Cl3N2O2Degré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :483.86Chlorothiazide
CAS :Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Formule :C7H6ClN3O4S2Degré de pureté :98.46% - 98.91%Couleur et forme :Crystals Physical Description Crystals; White Powder (Ntp 1992)Masse moléculaire :295.72Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)
CAS :Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat), also known as Human PTHrP (107-111) amide, is a C-terminal fragment of parathyroidFormule :C27H42N10O7Masse moléculaire :618.69Dexamethasone cipecilate
CAS :Dexamethasone cipecilate is a long-acting intranasal corticosteroid and a highly lipophilic anti-inflammatory corticosteroid.Formule :C33H43FO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :570.69Kisspeptin-14 human
CAS :Kisspeptin-14 human is an active fragment peptide of Kisspeptin encoded by the KiSS-1 gene. Kisspeptin-14 human is a GPR54 agonist for human and rat.Formule :C82H112N22O21Masse moléculaire :1741.9TD-802
CAS :TD-802, an AR-targeting PROTAC with microsomal stability, shows promise for castration-resistant prostate cancer.Formule :C52H61ClN10O6Couleur et forme :SolidMasse moléculaire :957.56LY255582
CAS :LY255582 is a selective centrally active opioid receptor antagonist with high affinity for mu, delta and kappa receptors with Ki of 0.4 nM, 5.2, 2.0 nM,Formule :C22H35NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.52Teriparatide
CAS :Teriparatide is an agonist of PHT(IC50 of 2 nM in HEK293 cells).Formule :C181H291N55O51S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4117.72Acetalin-2
CAS :Acetalin-2, an opioid peptide with the sequence Ac-Arg-Phe-Met-Trp-Met-Arg-NH2, selectively binds to [3 H]DAMGO with a Ki value of 93.3 nM [1].Formule :C44H66N14O7S2Masse moléculaire :967.21GNE-502
CAS :GNE-502 is an orally active and potent estrogen receptor (ER) degrader, specifically designed for research on breast cancer.Formule :C25H30FN3O3SCouleur et forme :SolidMasse moléculaire :471.59Diisononyl phthalate
CAS :Diisononyl phthalate (DINP), a phthalate, a plasticizer, activates the ACE/AT1R axis and inhibits NO production, inducing elevated blood pressure in mice.Formule :C26H42O4Degré de pureté :99.97%Couleur et forme :Colorless Liquid In Water (Uscg 1999)Masse moléculaire :418.61Clocinnamox mesylate
CAS :Clocinnamox mesylate: irreversible μ-opioid blocker; Ki: 0.7 nM (mouse μ), 1.9 nM (δ), 5.7 nM (κ).Formule :C30H33ClN2O7SCouleur et forme :SolidMasse moléculaire :601.11CP 85339
CAS :CP 85339 is an aspartic acid protease inhibitor for X-ray analysis of peptide-renin complexes.Formule :C31H49ClN4O6SCouleur et forme :SolidMasse moléculaire :641.26Ota-vasotocin
CAS :Ota-vasotocin is a ligand utilized in quantitative receptor autoradiography for oxytocin receptors.Formule :C54H79N11O13S2Masse moléculaire :1154.41PSDalpha
PSDalpha, a conjugate of PS, TB, and 17β-estradiol, degrades ERα with peak absorption at 465 nm, effectively inhibiting MCF-7 cell growth.Formule :C44H39N3O2SCouleur et forme :SolidMasse moléculaire :673.86TRV055
CAS :TRV055: Gq-biased AT1R ligand, stimulates Gq signaling, aids Gq-biased agonist development.Formule :C42H57N9O9Masse moléculaire :831.972Bufrolin
CAS :Bufrolin is a potent GPR35 agonist, mast cell stabilizer, and anti-inflammatory research agent.Formule :C18H16N2O6Couleur et forme :SolidMasse moléculaire :356.33AKR1C3-IN-10
AKR1C3-IN-10 (compound 5r), a selective inhibitor of AKR1C3 with an IC50 of 51 nM, demonstrates efficacy in a prostate cancer xenograft model [1].Formule :C24H20N4O3Couleur et forme :SolidMasse moléculaire :412.44Valsartan Methyl Ester
CAS :<p>Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.</p>Formule :C25H31N5O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :449.55Histamine & Melatonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>Couleur et forme :Odour Solid[Met5]-Enkephalin, amide
CAS :[Met5]-Enkephalin, amide activates δ and ζ opioid receptors; has multiple forms and varying plasma levels.Formule :C27H36N6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.68Potassium Channel Targeted Library
A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;Couleur et forme :Odour SolidRef: TM-L7300
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderAngiotensin II (1-4), human
CAS :Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Formule :C24H37N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :551.59Glucocorticoids receptor agonist 2
CAS :Arylpyrazole-based glucocorticoid agonist with potent anti-inflammatory effects; doesn't affect insulin secretion.Formule :C25H25FN2OCouleur et forme :SolidMasse moléculaire :388.48[Asp5]-Oxytocin
CAS :[Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity.Formule :C43H65N11O13S2Masse moléculaire :1008.18Morphiceptin
CAS :Morphiceptin is a synthetic tetrapeptide with morphinelike activities, highly specific for morphine receptors, but not for enkephalin receptors.Formule :C28H35N5O5Masse moléculaire :521.61PD 125967
CAS :PD 125967 is a renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension.Formule :C51H67N5O4Couleur et forme :SolidMasse moléculaire :814.11ERα degrader 10
ERα degrader10 is a potent, selective, orally active estrogen receptor α (ERα) degrader. It demonstrates strong ERα binding affinity (IC50 of 24.0 nM) and degradation capability (EC50 of 5.3 nM). This compound degrades ERα through a proteasome-mediated pathway and is utilized in breast cancer research.Couleur et forme :Odour Solid[Arg8]-Vasotocin
CAS :[Arg8]-Vasotocin is a hormone present in the neurohypophysis of nonmammalian vertebrates that is related to vasopressin and oxytocin.Formule :C43H67N15O12S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1050.22GLL 398
CAS :GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.Formule :C25H23BO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.26Ref: TM-T9997
1mg185,00€5mg415,00€10mg622,00€25mg1.119,00€50mg1.679,00€100mg2.520,00€200mg3.780,00€1mL*10mM (DMSO)424,00€Imidaprilate
CAS :Imidaprilate, an active TA-6366 metabolite, is a potent ACE inhibitor with an IC50 of 2.6 nM, researched for hypertension.Formule :C18H23N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.39[Sar1, Ile8]-Angiotensin II
CAS :[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.Formule :C46H73N13O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :968.15MOR agonist-2
Compound 46, designated as MOR agonist-2, serves as a D3R antagonist and a MOR agonist with respective K i values of 7.26 nM and 564 nM.Formule :C37H47Cl2N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :680.71ERD-308
CAS :ERD-308, potent at 5nM, achieves >95% ER degradation in ER+ breast cancer, with DC50 of 0.17-0.43 nM.Formule :C55H65N5O9S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1004.26Ocedurenone
CAS :<p>Ocedurenone, a corticosteroid receptor antagonist, is a compound utilized in the investigation of kidney disease (WO2018054357, compound I).</p>Formule :C28H30ClN5O2Couleur et forme :SolidMasse moléculaire :504.03WAY-298630
CAS :Fluorophenoxy benzimidazole, a CRTH2 blocker, IC50 < 10 μM for rhinitis, COPD, arthritis, eczema, conjunctivitis.Formule :C17H15FN2O3SDegré de pureté :97.84%Couleur et forme :SolidMasse moléculaire :346.38DPDPE
CAS :DPDPE is selective δ-opioid receptor agonist peptide.Formule :C30H39N5O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :645.79Dagrocorat hydrochloride
CAS :PF-0251802 HCl is a bio-active chemical.Formule :C29H30ClF3N2O2Couleur et forme :SolidMasse moléculaire :531.01Commendamide
CAS :Commendamide, natural, mimics N-acyl-amides, activates GPR132 with EC50 of 11.8 μM, made by Cbeg12 gene in commensal bacteria.Formule :C18H35NO4Couleur et forme :SolidMasse moléculaire :329.47Urotensin II (114-124), human
CAS :Human Urotensin II (114-124) is an 11-amino acid peptide with vasoconstrictor properties and agonizes GPR14.Formule :C64H85N13O18S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1388.57SR 43845
CAS :<p>SR 43845 is an inhibitor of renin.</p>Formule :C44H64N8O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :833.044Adrenocorticotropic hormone
CAS :ACTH, a polypeptide, is secreted by the pituitary gland and regulates cortisol and androgen.Couleur et forme :Solid1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone
CAS :Methyl-2-quinolone from Evodia rutaecarpa blocks angiotensin II receptor with 48.2 μM IC50.Formule :C25H35NOCouleur et forme :SolidMasse moléculaire :365.55PD 132002
CAS :PD 132002 is a renin inhibitor.Formule :C31H50N4O9SCouleur et forme :SolidMasse moléculaire :654.82Boc-ypgflt(O-tbu)
CAS :Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.Formule :C44H64N6O11Couleur et forme :SolidMasse moléculaire :853.01Faznolutamide
CAS :Faznolutamide is an antiandrogen agent [1] [2] .Formule :C19H17FN4O2SCouleur et forme :SolidMasse moléculaire :384.43PROTAC AR Degrader-9
PROTAC AR Degrader-9 (Compound c6) is a PROTAC-based degrader specifically targeting the androgen receptor. It effectively degrades the androgen receptor in human dermal papilla cells (HDPC) with a DC50 of 262.38 nM. Additionally, this compound enhances the expression of paracrine factors, such as TGF-β1 and β-catenin, thereby promoting hair regeneration in mouse models. [Pink: ligand for target protein AR ligand-38; Black: linker; Blue: ligand for E3 ligase Cereblon]Formule :C43H49ClN6O5Couleur et forme :SolidMasse moléculaire :765.339Cl-4AS-1
CAS :steroidal androgen receptor agonistFormule :C26H33ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.01Pro8-Oxytocin TFA
<p>Pro8-Oxytocin TFA, a modified oxytocin (OXT) ligand, exhibits greater potency and efficacy than the standard mammalian OXT ligand, Leu8-Oxytocin, at primate</p>Formule :C42H62N12O12S2·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidDetrothyronine
CAS :Detrothyronine is a biochemical.Formule :C15H12I3NO4Couleur et forme :SolidMasse moléculaire :650.97TRV-120027
CAS :TRV120027: β-arrestin-1-biased agonist, angiotensin II type 1 receptor, reduces vasoconstriction, boosts heart muscle contraction.Formule :C43H67N13O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :926.09PROTAC ERα Y537S degrader-1
CAS :PROTAC ERα Y537S degrader-1 comprises a ubiquitin E3 ligase binding group, a linker and a protein binding group.Formule :C46H49N5O6Couleur et forme :SolidMasse moléculaire :767.91(Rac)-SNC80
CAS :(Rac)-SNC80, a racemic δ-opioid agonist (K i 1.78 nM), shows potential for treating various headache disorders.Formule :C28H39N3O2Couleur et forme :SolidMasse moléculaire :449.63Locicortolone
CAS :Locicortolone is a synthetic glucocorticoid corticosteroid which was never marketed.Formule :C22H28Cl2O3Couleur et forme :SolidMasse moléculaire :411.36AL-438
CAS :AL-438 is a non-steroidal selective glucocorticoid receptor modulator.Formule :C23H25NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.45
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