Réductase
Les réductases sont une large classe d'enzymes qui catalysent la réduction de molécules dans diverses voies biochimiques. En endocrinologie, des réductases spécifiques, telles que la 5α-réductase, sont cruciales pour le métabolisme des hormones stéroïdes, y compris la conversion de la testostérone en dihydrotestostérone (DHT). Les inhibiteurs des enzymes réductases sont utilisés dans le traitement de conditions telles que l'hyperplasie bénigne de la prostate et l'alopécie androgénique. Chez CymitQuimica, nous offrons une variété d'inhibiteurs de réductases de haute qualité pour soutenir vos recherches en régulation hormonale, voies métaboliques et développement thérapeutique.
60 produits trouvés pour "Réductase".
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Epalrestat
CAS :Epalrestat (ONO2235), an aldose reductase inhibitor, helps manage diabetic neuropathy symptoms and slows disease progression.Formule :C15H13NO3S2Degré de pureté :99.2% - 99.66%Couleur et forme :Orange SolidMasse moléculaire :319.399Imirestat
CAS :Imirestat (HOE 843) is an aldose reductase inhibitor that can be used in diabetes research.Formule :C15H8F2N2O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :286.233Ref: TM-T15568
2mg34,00€1mL*10mM (DMSO)53,00€5mg54,00€10mg77,00€25mg140,00€50mg218,00€100mg350,00€200mg497,00€MK 0434
CAS :MK 0434 is a steroid 5α-reductase inhibitor and hormone antagonist associated with a significant reduction in DHT.Formule :C25H31NO2Degré de pureté :99.45% - 99.67%Couleur et forme :SolidMasse moléculaire :377.52Methotrexate
CAS :Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.Formule :C20H22N8O5Degré de pureté :96.84% - 99.91%Couleur et forme :Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisMasse moléculaire :454.44Alconil
CAS :Alconil is a biochemical.Formule :C15H9FN2O2Degré de pureté :99.32% - 99.34%Couleur et forme :SolidMasse moléculaire :268.24Trimethoprim
CAS :Trimethoprim (NSC-106568) inhibits dihydrofolate reductase, CYP2C8, and OCT2 - an antibacterial agent.Formule :C14H18N4O3Degré de pureté :99.80% - 99.81%Couleur et forme :SolidMasse moléculaire :290.3177Antitrypanosomal agent 1
CAS :Potent TR inhibitor with IC50: 3.3μM, also inhibits glutathione reductase (IC50: 64.8μM) and T. brucei (EC50: 1μM).Formule :C11H14Cl3NODegré de pureté :97.76%Couleur et forme :SolidMasse moléculaire :282.59Turosteride
CAS :Turosteride is a small molecule steroidal 5α-reductase (5α-reductase) inhibitor.Turosteride has antitumor activity for the treatment of oncologic diseases andFormule :C27H45N3O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :459.6645Aldose reductase-IN-1
CAS :Aldose reductase-IN-1 (AT-001, Caficrestat) is a highly potent inhibitor of aldose reductase.Cost-effective and quality-assured.Formule :C17H10F3N5O3SDegré de pureté :99.56% - 99.82%Couleur et forme :White SolidMasse moléculaire :421.353Ref: TM-T14175
1mg53,00€5mg114,00€1mL*10mM (DMSO)126,00€10mg174,00€25mg321,00€50mg484,00€100mg689,00€Fluvastatin sodium
CAS :Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFormule :C24H25FNNaO4Degré de pureté :98.54% - 99.56%Couleur et forme :SolidMasse moléculaire :433.45AT-007
CAS :AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM).Formule :C17H10F3N3O3S2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :425.405Ref: TM-T10393
1mg56,00€5mg105,00€1mL*10mM (DMSO)117,00€10mg176,00€25mg312,00€50mg505,00€100mg704,00€Gold(III) chloride
CAS :Gold(III) chloride inhibits thioredoxin reductase (IC50=0.065 µM) and thyroxine 5-deiodinase (IC50=0.57 µM), with anticancer and antimicrobial activities.Formule :AuCl3Masse moléculaire :303.32Isomer-Turosteride
Isomer-Turosteride, a novel 5α-reductase inhibitor, reduces prostate DHT and has anticancer properties without raising T levels.Formule :C27H45N3O3Degré de pureté :98.94%Couleur et forme :White SolidMasse moléculaire :459.67AKR1Cs-IN-1
AKR1Cs-IN-1 (Compound 29) is an effective and broad-spectrum inhibitor of the Aldo-Keto Reductase 1C family (AKR1C1-1C4). It achieves subtype inhibition by simultaneously binding to the SP2 and SP3 pockets, thereby blocking metabolic pathways related to drug resistance. In enzyme assays, AKR1Cs-IN-1 exhibits significant inhibitory activity with IC50 values of 0.09, 0.28, 0.05, and 0.51 µM for AKR1C1, AKR1C2, AKR1C3, and AKR1C4, respectively. The compound shows excellent resensitizing effects in doxorubicin (DOX)-resistant breast cancer cell line MCF-7/ADR, effectively enhancing the cytotoxicity of DOX. AKR1Cs-IN-1 holds promise for research on breast cancer resistance.Couleur et forme :Odour SolidAntitumor agent-195
Antitumor agent-195 (compound 16c) is a dual-targeting agent that simultaneously targets STAT3 and NQO1. At a concentration of 1 μM, it significantly inhibits the phosphorylation of STAT3 at the Tyr705 site and effectively induces apoptosis in MDA-MB-231 and MDA-MB-468 breast cancer cells. As a substrate of NQO1, Antitumor agent-195 markedly increases ROS production, causing severe DNA damage in a dose-dependent manner. It also demonstrates strong antitumor properties in MDA-MB-231 xenograft models.Formule :C22H22N2O4Couleur et forme :SolidMasse moléculaire :378.42ALR2-IN-6
ALR2-IN-6 (compound 9) is a potent competitive inhibitor of ALR2, with a Ki value of 0.064 μM. It is applicable in research related to neuropathy, retinopathy, and nephropathy.Formule :C21H19BrFN3OCouleur et forme :SolidMasse moléculaire :427.06955Oxidation-Reduction Compound Library
xnum small molecule compounds with pro-oxidant or anti-oxidant activity for high-throughput and high-content screening.Couleur et forme :Odour SolidRef: TM-L2900
1mgÀ demander10μL*10mM (DMSO)À demander20μL*10mM (DMSO)À demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderDDHF20
DDHF20 is an inhibitor of Staphylococcus aureus, specifically targeting and inhibiting its thioredoxin reductase (TrxR) by acting as a competitive inhibitor at the NADPH binding site. DDHF20 shows potential for research in combating infections related to Staphylococcus aureus.Formule :C34H28O4Couleur et forme :SolidMasse moléculaire :500.58ALR2-IN-1
CAS :ALR2-IN-1: potent, selective inhibitor of ALR2 (IC50=1.42 μM), antiglycemic, antioxidant; for diabetes research.Formule :C16H17N3O2SDegré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :315.39Myricetin-3-O-rutinoside
CAS :Myricetin-3-O-rutinoside is a flavonol glycoside and aldose reductase inhibitor with anti-neuroinflammatory effects.Formule :C27H30O17Degré de pureté :99.93%Masse moléculaire :626.52
