Endocrinologie/Hormones
Les inhibiteurs en endocrinologie/hormonaux sont des composés qui bloquent l'action des hormones ou interfèrent avec les voies de signalisation hormonales. Ces inhibiteurs sont essentiels pour étudier la régulation des systèmes endocriniens et pour développer des traitements pour les maladies liées aux hormones, telles que le diabète, les troubles de la thyroïde et les cancers hormonodépendants. En modulant l'activité hormonale, ces inhibiteurs peuvent aider à élucider les interactions complexes au sein du système endocrinien. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité en endocrinologie/hormonaux pour soutenir vos recherches en endocrinologie, pharmacologie et sciences médicales.
Sous-catégories appartenant à la catégorie "Endocrinologie/Hormones"
- Récepteur des androgènes(229 produits)
- Annexine A(16 produits)
- Aromatase(22 produits)
- Récepteur d'œstrogène/progestatif(60 produits)
- GPR(1 produits)
- Récepteur des glucocorticoïdes(165 produits)
- LHRH(2 produits)
- Récepteur opioïde(325 produits)
- Récepteur de prostaglandine(122 produits)
- RAAS(89 produits)
- Réductase(50 produits)
- Somatostatine(57 produits)
- Récepteur des hormones thyroïdiennes (THR)(32 produits)
- Récepteur de la vasopressine(48 produits)
Affichez 6 plus de sous-catégories
3371 produits trouvés pour "Endocrinologie/Hormones"
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Estrone-N-O-C1-amido
CAS :Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derived from Estrone that specifically binds to estrogen receptor α (ERα).Formule :C20H26N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :342.439Urotensin II, mouse
CAS :UTS2 is a human gene, alias U-II, on chromosome 1p36.23, codes for Urotensin-II, a potent vasoconstrictor. Formula: C64H85N13O18S2, Molar mass: 1388.6 g/mol.
Formule :C76H100N18O19S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1633.86PROTAC ERα Degrader-1
PROTAC ERα Degrader-1 is a chemical compound.Formule :C66H69N7O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1120.29Arzoxifene
CAS :Arzoxifene (LY353381), an oral SERM, combats breast cancer, supports bone health, and improves lipids, with few side effects.Formule :C28H29NO4SCouleur et forme :SolidMasse moléculaire :475.6Imlunestrant tosylate
CAS :Imlunestrant (LY-3484356) tosylate, an oral SERD, targets ER+ aBC/EEC by blocking estrogen receptors and gene transcription.Formule :C36H32F4N2O6SCouleur et forme :SolidMasse moléculaire :696.71Melanin Concentrating Hormone, salmon
CAS :Melanin Concentrating Hormone (MCH), a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.Formule :C89H139N27O24S4Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :2099.48RS 21314
CAS :RS 21314 is a thiol ester corticosteroid that is topical.Formule :C24H30F2O5SCouleur et forme :SolidMasse moléculaire :468.55Orphanin FQ(1-11)
CAS :Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.
Formule :C49H75N15O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1098.218-Oxocortisol
CAS :18-Oxocortisol, a naturally occurring mineralocorticoid and adrenal biomarker, is produced by CYP11B2.
Formule :C21H28O6Couleur et forme :SolidMasse moléculaire :376.449ARD-2051
CAS :ARD-2051 is a potent, orally active proteolysis-targeting chimera degrader of the androgen receptor (AR), exhibiting DC50 values of 0.6 nM in degrading ARFormule :C43H45ClN8O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :789.32Raloxifene 6-Monomethyl Ether
CAS :Compound 7, Raloxifene 6-Monomethyl Ether, blocks estrogen receptor α, inhibits MCF-7 cells; IC50=250 nM, pIC50=6.6.Formule :C29H29NO4SCouleur et forme :SolidMasse moléculaire :487.61Handle region peptide, rat
CAS :Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.Formule :C54H101N15O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1184.54PROTAC ER Degrader-15
PROTAC ER Degrader-15 (Compound 40) is an orally active estrogen receptor (ER) degrader with anticancer properties, suitable for breast cancer research.Formule :C47H47F4N5O5Couleur et forme :SolidMasse moléculaire :837.9Dynorphin A (1-8)
CAS :Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.Formule :C46H72N14O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :981.151-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
CAS :1-Methyl-quinolone alkaloid inhibits DAG acyltransferase, blocks angiotensin II receptor (IC50s: 20.1 & 34.1 μM), and fights H. pylori (MIC: 10 μg/mL).Formule :C23H31NOCouleur et forme :SolidMasse moléculaire :337.5Raloxifene 4'-glucuronide
CAS :Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene.
Formule :C34H35NO10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :649.71[Nphe1]Nociceptin(1-13)NH2
CAS :Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.Formule :C61H100N22O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1381.6Olmesartan medoxomil impurity C
CAS :Impurity C of Olmesartan medoxomil is a selective AT1 inhibitor with an IC50 of 66.2 μM.Formule :C29H28N6O5Couleur et forme :SolidMasse moléculaire :540.57Azilsartan Medoxomil Potassium
CAS :Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.Formule :C30H23N4O8·KDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :606.62Hydrocortisone sodium succinate
CAS :Hydrocortisone sodium succinate is a glucocorticoid which is used to alleviate allergic reactions, particularly those of the skin and gums.Formule :C25H34NaO8Couleur et forme :SolidMasse moléculaire :485.529L 363564
CAS :L 363564 is a kidney renin inhibitor.Formule :C54H76N12O10Couleur et forme :SolidMasse moléculaire :1053.276ST-CY14
ST-CY14 is an inhibitor of the Nur77-PPARγ interaction with an EC50 of 3.15 μM. It binds to Nur77 (Kd=32 nM) to prevent its ubiquitination and degradation by PPARγ, reducing fatty acid uptake and mitochondrial respiration, and inhibiting the transcription of CD36 and FABP4. ST-CY14 suppresses proliferation and migration of MCF7 and MDA-MB-231 cancer cells and impedes tumor growth and bone metastasis in mouse models.Formule :C139H237N57O31S2Couleur et forme :SolidMasse moléculaire :3266.86PTP1B/AKR1B1-IN-2
PTP1B/AKR1B1-IN-2 (Compound 7f) is a potent inhibitor targeting both PTP1B and AKR1B1 with IC50 values of 3.2 and 2.1 μM, respectively, and K i values of 4.0Formule :C23H23NO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.56AZ 1729
CAS :FFA2 modulator; inhibits cAMP, enhances 35SGTPγS binding (pEC50: 6.9, 7.23); alters Gi/Gq signaling; affects lipolysis, neutrophil migration.
Formule :C18H16FN5OSCouleur et forme :SolidMasse moléculaire :369.42Estrogen receptor modulator 6
CAS :ER modulator 6 (3a) is a potent ERβ agonist with a K i of 0.44 nM; 19x more selective for ERβ than ERα.
Formule :C18H16F2O3Couleur et forme :SolidMasse moléculaire :318.32Ro 64-6198
CAS :Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.Formule :C26H31N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.54AKR1B10-IN-1
CAS :AKR1B10-IN-1: potent AKR1B10 inhibitor, IC50 3.5 nM; hinders lung cancer cell growth, spread, and Cisplatin resistance.Formule :C19H16FNO4Couleur et forme :SolidMasse moléculaire :341.338UFP-101
CAS :Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.
Formule :C82H138N32O21Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1908.19T4-ATA (S-isomer)
T4-ATA S-isomer, the active form of the thyroid hormone, represents the S-isomer of T4-ATA.Formule :C19H15I4NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :893.01U-54494A hydrochloride
CAS :U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.Formule :C18H25Cl3N2OCouleur et forme :SolidMasse moléculaire :391.76[Sar1, Ile8]-Angiotensin II TFA
[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.Formule :C48H74F3N13O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1082.18Herkinorin
CAS :Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.Formule :C28H30O8Couleur et forme :SolidMasse moléculaire :494.53PROTAC ER Degrader-3
CAS :PROTAC ER Degrader-3 from patent WO2017201449A1 is a PAC synthesis intermediate for ADC/PROTAC antibody conjugates, boosting ERα degradation.Formule :C71H77N7O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1220.434Alclometasone
CAS :Alclometasone is a glucocorticoid that reduces inflammation and treats various skin conditions like eczema and psoriasis.Formule :C22H29ClO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.92Dynorphin B (1-13)
CAS :Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.Formule :C74H115N21O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1570.84Antihypertensive agent 3
Antihypertensive agent 3 (compound 4a), an angiotensin II receptor 1 antagonist, demonstrates antihypertensive activity in spontaneously hypertensive rats (SHRsFormule :C16H13NO4SCouleur et forme :SolidMasse moléculaire :315.34Neuropeptide AF (human)
CAS :Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.Formule :C90H132N26O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1978.173-Cl-Pyridine-amide-acrylaldehyde-piperazine
3-Cl-Pyridine-amide-acrylaldehyde-piperazine serves as a synthetic intermediate for LO-4-25. LO-4-25 is a ligand for the androgen receptor (AR) DNA binding domain and is linked to a truncated fumaramide handle via a connector. In 22Rv1 cells, LO-4-25 demonstrates potent degradation of both AR and AR-V7.Couleur et forme :Odour SolidAntihypertensive agent 2
Antihypertensive agent 2 (Compound 4g) exhibits effective antagonistic activities against angiotensin II receptor 1 and reduces blood pressure with equal orFormule :C22H15NO3Couleur et forme :SolidMasse moléculaire :341.36CTAP
CAS :Potent μ opioid antagonist, IC50 3.5 nM, 1200x selectivity over δ and somatostatin, brain-penetrant, active in vivo.Formule :C51H69N13O11S2Degré de pureté :98%Couleur et forme :White Solid/PowderMasse moléculaire :1104.32SL910102
CAS :SL910102 is a nonpeptide angiotensin antagonist of the AT1 receptor.Formule :C30H30N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.60β-Naltrexamine dihydrochloride
CAS :β-Naltrexamine dihydrochloride is an orally administered, irreversible opioid receptor antagonist. Its derivatives exhibit optimised subtype selectivity and can be used for pain research.Formule :C20H28Cl2N2O3Degré de pureté :95.98%Couleur et forme :SoildMasse moléculaire :415.35CTOP
CAS :Potent μ-receptor antagonist, Ki=0.96nM, ineffective at δ (>10,000nM). Alters behavior in vivo, boosts K+ currents in rat neurons in vitro, μ-independent.Formule :C50H67N11O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1062.28Cebranopadol hemicitrate
CAS :Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.Couleur et forme :SolidThyroxine sulfate
CAS :Thyroxine sulfate is a sulfoconjugated derivative of Thyroxine and is also a metabolite of Thyroxine.Formule :C15H11I4NO7SCouleur et forme :SolidMasse moléculaire :856.93Gluten Exorphin B5
CAS :Gluten exorphin B5 (GE-B5) is a food-derived opioid peptide identified in digests of wheat gluten.Formule :C30H38N6O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.66Estrogen receptor modulator 13
Estrogen receptor modulator13 (Compound 5D) is an estrogen receptor antagonist with significant cytotoxic effects on MCF7 cells, exhibiting an IC50 value of 8.50 μM. Estrogen receptor modulator13 holds potential for breast cancer research.Formule :C25H19ClN2O2SCouleur et forme :SolidMasse moléculaire :446.08558ARD-69
ARD-69, a potent PROTAC, degrades AR in prostate cancer, with low DC50 values in AR+ cell lines, and suppresses AR gene expression.Formule :C62H74ClFN8O7SCouleur et forme :SolidMasse moléculaire :1129.83Lactandrate
CAS :Lactandrate is a homo-aza-steroidal ester of p-bis(2-chloroethyl) amino phenyl acetic acid.Formule :C31H44Cl2N2O3Couleur et forme :SolidMasse moléculaire :563.67β-Hydroxy-epi-androsterone
CAS :7β-Hydroxy-epi-androsterone (7β-Hydroxy-EpiA) is an endogenous androgenic derivative of dehydroepiandrosterone that possesses the ability to bind to ERβ,Formule :C19H30O3Couleur et forme :SolidMasse moléculaire :306.44CP-472555
CAS :CP-472555 is a selective nonsteroidal glucocorticoid receptor antagonist with anti-GR and anti-obesity activity in animal models.Formule :C31H32N2O2Couleur et forme :SolidMasse moléculaire :464.60[Arg14,Lys15]Nociceptin
CAS :Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.Formule :C82H137N31O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1909.18THR-β agonist 6
CAS :THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μMFormule :C20H14Cl2N6O3Couleur et forme :SolidMasse moléculaire :457.27β-Endorphin, equine
CAS :Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain.Formule :C154H248N42O44SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3423.94DPP-4/GPR119 modulator 1
CAS :Orally active DPP-4 inhibitor/GPR119 agonist, Compound 22 lowers glucose, moderate hERG inhibition, IC50 4.9 µM, for diabetes research.Formule :C30H39ClN10O3Couleur et forme :SolidMasse moléculaire :623.15Bexirestrant
CAS :Bexirestrant is an orally active ER-α degrader commonly employed in the research of antiestrogen and antineoplastic therapies.Formule :C29H26F3NO2Couleur et forme :SolidMasse moléculaire :477.527Ganoderic acid Df
CAS :Ganoderic acid Df, a lanostane triterpenoid from Ganoderma lucidum, inhibits aldose reductase with IC50 of 22.8 μM.Formule :C30H44O7Couleur et forme :SolidMasse moléculaire :516.67Inocoterone acetate
CAS :Inocoterone acetate is a nonsteroidal antiandrogen that binds to the androgen receptor and possesses antiandrogenic activity in animal models.Formule :C18H26O3Couleur et forme :SolidMasse moléculaire :290.40AM-5262
CAS :AM-5262 is a potent GPR40 Full Agonist with improved rat PK profile and general selectivity profile.Formule :C33H35FO4Couleur et forme :SolidMasse moléculaire :514.63ER degrader 4
CAS :ER degrader 4, a selective and orally active compound, effectively degrades estrogen receptors and exhibits anti-tumor activity [1].Formule :C26H19FO4SCouleur et forme :SolidMasse moléculaire :446.49Antidiabetic agent 15
Antidiabetic agent 15 (compound 1B15) acts as a dual inhibitor of AT1R and NEP, reducing oxidative stress and restoring mitochondrial membrane potential.Formule :C26H23NO5Couleur et forme :SolidMasse moléculaire :429.15762Nurr1 agonist 12
Nurr1 agonist 12 (Compound 37) acts as an agonist of the nuclear receptor-related protein 1 (Nurr1), enhancing its transcriptional activity with an EC50 of 0.06 μM. It stimulates human response elements NBRE, NurRE, and DR5 with EC50 values of 0.07 μM, 0.027 μM, and 0.014 μM, respectively. Additionally, Nurr1 agonist 12 induces the expression of neurotrophic genes regulated by Nurr1, such as tyrosine hydroxylase (TH), SOD1/2, BDNF, Sestrin 3, and BIRC5 (Survivin). The compound also demonstrates neuroprotective effects against neurotoxicity caused by Paraquat.Formule :C18H12ClN3OCouleur et forme :SolidMasse moléculaire :321.76Myrciacetin
CAS :Myrciacetin from Rhododendron inhibits rat aldose reductase with IC50 of 13 μM.Formule :C17H16O6Couleur et forme :SolidMasse moléculaire :316.309Epi-Cryptoacetalide
Epi-Cryptoacetalide is a useful organic compound for research related to life sciences and the catalog number is T126054.Formule :C18H22O3Couleur et forme :SolidMasse moléculaire :286.371ODM-204
CAS :ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme(IC50s of 80 nM and 22 nM, respectively).Formule :C20H21F3N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.40MT-7716 hydrochloride
CAS :MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP)Formule :C27H29ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477(S,S)-J-113397
CAS :(S,S)-J-113397 is an isomer of J-113397 . J-113397 is an Opioid Receptor antagonist [1] .Formule :C24H37N3O2Couleur et forme :SolidMasse moléculaire :399.57GPR88 agonist 2
GPR88 agonist 2 (compound 53) serves as a potent, brain-penetrant agonist of GPR88, exhibiting an EC50 of 14 µM in the GPR88 cAMP functional assay [1].Couleur et forme :Odour SolidGalloylalbiflorin
CAS :Galloylalbiflorin, an AR antagonist with IC50 53.3μM, is sourced from Paeonia lactiflora roots, exhibiting anti-androgenic properties.Formule :C30H32O15Couleur et forme :SolidMasse moléculaire :632.57TD-802
CAS :TD-802, an AR-targeting PROTAC with microsomal stability, shows promise for castration-resistant prostate cancer.Formule :C52H61ClN10O6Couleur et forme :SolidMasse moléculaire :957.56GNE-502
CAS :GNE-502 is an orally active and potent estrogen receptor (ER) degrader, specifically designed for research on breast cancer.Formule :C25H30FN3O3SCouleur et forme :SolidMasse moléculaire :471.59Clocinnamox mesylate
CAS :Clocinnamox mesylate: irreversible μ-opioid blocker; Ki: 0.7 nM (mouse μ), 1.9 nM (δ), 5.7 nM (κ).Formule :C30H33ClN2O7SCouleur et forme :SolidMasse moléculaire :601.11CP 85339
CAS :CP 85339 is an aspartic acid protease inhibitor for X-ray analysis of peptide-renin complexes.Formule :C31H49ClN4O6SCouleur et forme :SolidMasse moléculaire :641.26PSDalpha
PSDalpha, a conjugate of PS, TB, and 17β-estradiol, degrades ERα with peak absorption at 465 nm, effectively inhibiting MCF-7 cell growth.Formule :C44H39N3O2SCouleur et forme :SolidMasse moléculaire :673.86Bufrolin
CAS :Bufrolin is a potent GPR35 agonist, mast cell stabilizer, and anti-inflammatory research agent.Formule :C18H16N2O6Couleur et forme :SolidMasse moléculaire :356.33[Met5]-Enkephalin, amide
CAS :[Met5]-Enkephalin, amide activates δ and ζ opioid receptors; has multiple forms and varying plasma levels.Formule :C27H36N6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.68Angiotensin II (1-4), human
CAS :Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Formule :C24H37N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :551.59Glucocorticoids receptor agonist 2
CAS :Arylpyrazole-based glucocorticoid agonist with potent anti-inflammatory effects; doesn't affect insulin secretion.Formule :C25H25FN2OCouleur et forme :SolidMasse moléculaire :388.48PD 125967
CAS :PD 125967 is a renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension.Formule :C51H67N5O4Couleur et forme :SolidMasse moléculaire :814.111-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone
CAS :Methyl-2-quinolone from Evodia rutaecarpa blocks angiotensin II receptor with 48.2 μM IC50.Formule :C25H35NOCouleur et forme :SolidMasse moléculaire :365.55PD 132002
CAS :PD 132002 is a renin inhibitor.Formule :C31H50N4O9SCouleur et forme :SolidMasse moléculaire :654.82Boc-ypgflt(O-tbu)
CAS :Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.Formule :C44H64N6O11Couleur et forme :SolidMasse moléculaire :853.01Faznolutamide
CAS :Faznolutamide is an antiandrogen agent [1] [2] .Formule :C19H17FN4O2SCouleur et forme :SolidMasse moléculaire :384.43PROTAC ERα Y537S degrader-1
CAS :PROTAC ERα Y537S degrader-1 comprises a ubiquitin E3 ligase binding group, a linker and a protein binding group.Formule :C46H49N5O6Couleur et forme :SolidMasse moléculaire :767.91(Rac)-SNC80
CAS :(Rac)-SNC80, a racemic δ-opioid agonist (K i 1.78 nM), shows potential for treating various headache disorders.Formule :C28H39N3O2Couleur et forme :SolidMasse moléculaire :449.63[Ala17]-MCH
CAS :Potent MCH receptor agonist with EC50 of 17 nM (MCH1) & 54 nM (MCH2); prefers MCH1 (Ki 0.16 nM) over MCH2 (Ki 34 nM).Formule :C97H155N29O26S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2271.71Raloxifene 4-Monomethyl Ether
CAS :Raloxifene 4-Monomethyl Ether (Compound 37), an estrogen receptor α inhibitor, has an IC50 of 1 μM against MCF-7 cells.Formule :C29H29NO4SCouleur et forme :SolidMasse moléculaire :487.61Saralasin
CAS :Competitive non-selective angiotensin II antagonist.Formule :C42H65N13O10Degré de pureté :98%Couleur et forme :PowderMasse moléculaire :912Triamcinolone Benetonide
CAS :Triamcinolone benetonide is a synthetic glucocorticoid corticosteroid exhibiting potent anti-inflammatory properties.Formule :C35H42FNO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :623.71Ac-RYYRWK-NH2
CAS :Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.Formule :C49H69N15O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1012.17AZ'6421
CAS :"AZ'6421: A PROTAC degrading estrogen receptor alpha; potent in anti-tumor activity, useful for cancer research."Formule :C52H65F3N6O7SCouleur et forme :SolidMasse moléculaire :975.17Naldemedine
CAS :Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. It's well tolerated with minor GI issues.Formule :C32H34N4O6Couleur et forme :SolidMasse moléculaire :570.64BigLEN(rat)
CAS :Potent GPR171 agonist (EC50 = 1.6 nM). ProSAAS-derived peptide. Regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells.Formule :C76H128N24O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1746ER degrader 5
CAS :ER degrader 5: potent ER degrader, anti-cancer, for breast cancer research.Formule :C26H18F2O4SCouleur et forme :SolidMasse moléculaire :464.48C-Type Natriuretic Peptide (1-53), human
CAS :CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.Formule :C251H417N81O71S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5801.77RLA-5331
RLA-5331: iron activator with anti-androgen properties; inhibits mCRPC cell proliferation.Formule :C40H43F3N6O7SCouleur et forme :SolidMasse moléculaire :808.87PD 123177
CAS :PD 123177 is an inhibitor of Nonpeptide angiotensin AII-2.Formule :C29H28N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :480.56AKR1Cs-IN-1
AKR1Cs-IN-1 (Compound 29) is an effective and broad-spectrum inhibitor of the Aldo-Keto Reductase 1C family (AKR1C1-1C4). It achieves subtype inhibition by simultaneously binding to the SP2 and SP3 pockets, thereby blocking metabolic pathways related to drug resistance. In enzyme assays, AKR1Cs-IN-1 exhibits significant inhibitory activity with IC50 values of 0.09, 0.28, 0.05, and 0.51 µM for AKR1C1, AKR1C2, AKR1C3, and AKR1C4, respectively. The compound shows excellent resensitizing effects in doxorubicin (DOX)-resistant breast cancer cell line MCF-7/ADR, effectively enhancing the cytotoxicity of DOX. AKR1Cs-IN-1 holds promise for research on breast cancer resistance.Couleur et forme :Odour Solid[Orn8]-Urotensin II
CAS :[Orn8]-Urotensin II is a Urotensin receptor ligand and a partial agonist at Urotensin receptors.Formule :C63H83N13O18S2Couleur et forme :SolidMasse moléculaire :1374.5517-Epiestriol
CAS :17-Epiestriol, metabolite of estrone, forms via 16α-hydroxy intermediate and binds ERα and ERβ with affinity less than 17β-estradiol.Formule :C18H24O3Couleur et forme :SolidMasse moléculaire :288.38
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