Endocrinologie/Hormones
Les inhibiteurs en endocrinologie/hormonaux sont des composés qui bloquent l'action des hormones ou interfèrent avec les voies de signalisation hormonales. Ces inhibiteurs sont essentiels pour étudier la régulation des systèmes endocriniens et pour développer des traitements pour les maladies liées aux hormones, telles que le diabète, les troubles de la thyroïde et les cancers hormonodépendants. En modulant l'activité hormonale, ces inhibiteurs peuvent aider à élucider les interactions complexes au sein du système endocrinien. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité en endocrinologie/hormonaux pour soutenir vos recherches en endocrinologie, pharmacologie et sciences médicales.
Sous-catégories appartenant à la catégorie "Endocrinologie/Hormones"
- Récepteur des androgènes(230 produits)
- Annexine A(16 produits)
- Aromatase(23 produits)
- Récepteur d'œstrogène/progestatif(66 produits)
- GPR(1 produits)
- Récepteur des glucocorticoïdes(165 produits)
- LHRH(2 produits)
- Récepteur opioïde(327 produits)
- Récepteur de prostaglandine(126 produits)
- RAAS(89 produits)
- Réductase(51 produits)
- Somatostatine(57 produits)
- Récepteur des hormones thyroïdiennes (THR)(34 produits)
- Récepteur de la vasopressine(48 produits)
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3421 produits trouvés pour "Endocrinologie/Hormones"
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Biotin-Oxytocin
Biotin-Oxytocin (Biotin-α-Hypophamine; Biotin-Oxytocic hormone) is a biologically active peptide. It is oxytocin labeled with biotin at the N-terminus.Formule :C53H80N14O14S3Masse moléculaire :1232.514067β-Hydroxy-epi-androsterone
CAS :7β-Hydroxy-epi-androsterone (7β-Hydroxy-EpiA) is an endogenous androgenic derivative of dehydroepiandrosterone that possesses the ability to bind to ERβ,Formule :C19H30O3Couleur et forme :SolidMasse moléculaire :306.44CP-472555
CAS :CP-472555 is a selective nonsteroidal glucocorticoid receptor antagonist with anti-GR and anti-obesity activity in animal models.Formule :C31H32N2O2Couleur et forme :SolidMasse moléculaire :464.60[Arg14,Lys15]Nociceptin
CAS :Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.Formule :C82H137N31O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1909.18[Asp5]-Oxytocin acetate
[Asp5]-Oxytocin acetate: a biologically active neurohypophyseal hormone analogue, inducing uterine contractions, effects magnified by Mg2+.Formule :C45H69N11O15S2Masse moléculaire :1068.22ARD-266
CAS :ARD-266 is a PROTAC degrader based on the von Hippel-Lindau E3 ligase that induces the degradation of AR proteins and is useful in prostate cancer research.Formule :C52H59ClN6O7Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :915.51THR-β agonist 6
CAS :THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μMFormule :C20H14Cl2N6O3Couleur et forme :SolidMasse moléculaire :457.27BPRMU191
CAS :BPRMU191 is a distinct mu-opioid receptor (MOR) modulator with an EC50 of 2.17 μM in FLIPR Ca2+ assays conducted on CHO-K1/MOR/Gα15 cells. Additionally, BPRMU191 interacts with MOR in the presence of naloxone.Formule :C17H14FNO3SCouleur et forme :SolidMasse moléculaire :331.36Deltorphin
CAS :Deltorphin (Dermenkephalin) is Isolated from the skin of Phyllomedusa Sauvage. It also has an affinity to the opioid receptor.Formule :C44H62N10O10S2Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :955.15β-Endorphin, equine
CAS :Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain.Formule :C154H248N42O44SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3423.94DPP-4/GPR119 modulator 1
CAS :Orally active DPP-4 inhibitor/GPR119 agonist, Compound 22 lowers glucose, moderate hERG inhibition, IC50 4.9 µM, for diabetes research.Formule :C30H39ClN10O3Couleur et forme :SolidMasse moléculaire :623.15Bexirestrant
CAS :Bexirestrant is an orally active ER-α degrader commonly employed in the research of antiestrogen and antineoplastic therapies.Formule :C29H26F3NO2Couleur et forme :SolidMasse moléculaire :477.527Valsartan Methyl Ester
CAS :Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.
Formule :C25H31N5O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :449.55Ganoderic acid Df
CAS :Ganoderic acid Df, a lanostane triterpenoid from Ganoderma lucidum, inhibits aldose reductase with IC50 of 22.8 μM.Formule :C30H44O7Couleur et forme :SolidMasse moléculaire :516.67Inocoterone acetate
CAS :Inocoterone acetate is a nonsteroidal antiandrogen that binds to the androgen receptor and possesses antiandrogenic activity in animal models.Formule :C18H26O3Couleur et forme :SolidMasse moléculaire :290.40Saprisartan
CAS :Saprisartan (GR-138950, GR-138950X) is an AT1 receptor antagonist used for the treatment of heart failure and blood pressure.Formule :C25H22BrF3N4O4SCouleur et forme :SolidMasse moléculaire :611.43AM-5262
CAS :AM-5262 is a potent GPR40 Full Agonist with improved rat PK profile and general selectivity profile.Formule :C33H35FO4Couleur et forme :SolidMasse moléculaire :514.63ER degrader 4
CAS :ER degrader 4, a selective and orally active compound, effectively degrades estrogen receptors and exhibits anti-tumor activity [1].Formule :C26H19FO4SCouleur et forme :SolidMasse moléculaire :446.49Antidiabetic agent 15
Antidiabetic agent 15 (compound 1B15) acts as a dual inhibitor of AT1R and NEP, reducing oxidative stress and restoring mitochondrial membrane potential.Formule :C26H23NO5Couleur et forme :SolidMasse moléculaire :429.15762Nurr1 agonist 12
Nurr1 agonist 12 (Compound 37) acts as an agonist of the nuclear receptor-related protein 1 (Nurr1), enhancing its transcriptional activity with an EC50 of 0.06 μM. It stimulates human response elements NBRE, NurRE, and DR5 with EC50 values of 0.07 μM, 0.027 μM, and 0.014 μM, respectively. Additionally, Nurr1 agonist 12 induces the expression of neurotrophic genes regulated by Nurr1, such as tyrosine hydroxylase (TH), SOD1/2, BDNF, Sestrin 3, and BIRC5 (Survivin). The compound also demonstrates neuroprotective effects against neurotoxicity caused by Paraquat.Formule :C18H12ClN3OCouleur et forme :SolidMasse moléculaire :321.76Myrciacetin
CAS :Myrciacetin from Rhododendron inhibits rat aldose reductase with IC50 of 13 μM.Formule :C17H16O6Couleur et forme :SolidMasse moléculaire :316.309Epi-Cryptoacetalide
Epi-Cryptoacetalide is a useful organic compound for research related to life sciences and the catalog number is T126054.Formule :C18H22O3Couleur et forme :SolidMasse moléculaire :286.371Keap1-IN-1
Keap1-IN-1 (Compound 27) is an inhibitor of Keap1, functioning by covalently modifying the Cys151 residue on the BTB domain of KEAP1, thereby disrupting the interaction between Keap and Nrf. It enhances the mRNA expression of the antioxidant response element (ARE) dependent gene NQO1, with an EC50 of 160 nM, and exhibits cytotoxicity in U2OS cells, with an EC50 of 527 nM.Formule :C17H21Cl2N2O5PS3Couleur et forme :SolidMasse moléculaire :531.434LY2623091
CAS :LY2623091, a mineralocorticoid receptor antagonist, is utilized in treating refractory hypertension. It demonstrates CYP3A4-dependent clearance and exhibits synergistic effects when combined with CYP3A4 inhibitors.Formule :C30H30FN5O3Couleur et forme :SolidMasse moléculaire :527.59ODM-204
CAS :ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme(IC50s of 80 nM and 22 nM, respectively).Formule :C20H21F3N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.40MT-7716 hydrochloride
CAS :MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP)Formule :C27H29ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477(S,S)-J-113397
CAS :(S,S)-J-113397 is an isomer of J-113397 . J-113397 is an Opioid Receptor antagonist [1] .Formule :C24H37N3O2Couleur et forme :SolidMasse moléculaire :399.57pTH (1-37) (human)
CAS :pTH (1-37) human fragment boosts cAMP, alkaline phosphatase, growth, and BMD, potential for osteoporosis research.Formule :C195H316N58O54S2Couleur et forme :SolidMasse moléculaire :4401.08TRV055 acetate
TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.Formule :C44H61N9O11Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :892.01Ref: TM-T40220L
1mg109,00€2mg154,00€5mg235,00€10mg349,00€1mL*10mM (DMSO)389,00€25mg532,00€50mg745,00€100mg999,00€200mg1.333,00€BIBS 39
CAS :BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.Formule :C32H36N4O3Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :524.65β-Lipotropin (61-69)
CAS :β-Lipotropin (61-69) is a potent opioid agonist [1] [2] .Formule :C45H66N10O15SMasse moléculaire :1019.13PL-017 TFA
PL-017 TFA: μ opioid agonist, IC50 5.5 nM, long-lasting analgesia in rats.Formule :C31H38F3N5O7Masse moléculaire :649.66(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)
CAS :'(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat), a peptide, functions as a ligand for parathyroid hormone (PTH) receptors [1].'Formule :C194H303N59O53Masse moléculaire :4309.85PROTAC ERα Degrader-10
CAS :PROTACERα Degrader-10 (Compound 160a) is an orally bioavailable ERα degrader with a DC50 of 0.37-1.1 nM in MCF7, T47D, and CAMA-1 cells. It demonstrates antitumor activity in mouse models.Formule :C45H49N5O4Masse moléculaire :723.9Kalata B7
CAS :Kalata B7, a cyclotide isolated from Oldenlandia affinis DC (Rubiaceae), possesses membrane-permeating capabilities and acts as a partial agonist of oxytocin- and vasopressin V1a-receptors [1] [2].Formule :C128H196N36O40S6Masse moléculaire :3071.53Acetalin-3
CAS :Acetalin-3 (Ac-RFMWMT-NH2) is a hexapeptide that acts as a μ opioid receptor antagonist, displaying high affinity for μ and κ3 opioid receptors, weak affinity for κ1 receptors, and no affinity for κ2 receptors [1].Formule :C42H61N11O8S2Masse moléculaire :912.13GPR88 agonist 2
GPR88 agonist 2 (compound 53) serves as a potent, brain-penetrant agonist of GPR88, exhibiting an EC50 of 14 µM in the GPR88 cAMP functional assay [1].Couleur et forme :Odour SolidGalloylalbiflorin
CAS :Galloylalbiflorin, an AR antagonist with IC50 53.3μM, is sourced from Paeonia lactiflora roots, exhibiting anti-androgenic properties.Formule :C30H32O15Couleur et forme :SolidMasse moléculaire :632.57[Sar1, Ile8]-Angiotensin II acetate
'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.Formule :C48H77N13O12Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :1028.2Ref: TM-T7575L1
2mg34,00€5mg46,00€10mg60,00€1mL*10mM (DMSO)90,00€25mg119,00€50mg192,00€100mg289,00€200mg415,00€Axelopran sulfate
CAS :Axelopran sulfate is used in Oral Therapies for Opioid-induced Bowel Dysfunction in Patients with Chronic Noncancer Pain.Formule :C26H41N3O8SCouleur et forme :SolidMasse moléculaire :555.68ErSO
CAS :ErSO is a selective activator of anticipatory unfolded protein response (UPR) via ERα receptor. ErSO can be used in studies about anti-cancer.Formule :C22H13F6NO3Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :453.33Ref: TM-T39980
500mgÀ demander1mg71,00€5mg161,00€1mL*10mM (DMSO)172,00€10mg250,00€25mg411,00€50mg577,00€100mg772,00€TD-802
CAS :TD-802, an AR-targeting PROTAC with microsomal stability, shows promise for castration-resistant prostate cancer.Formule :C52H61ClN10O6Couleur et forme :SolidMasse moléculaire :957.56GNE-502
CAS :GNE-502 is an orally active and potent estrogen receptor (ER) degrader, specifically designed for research on breast cancer.Formule :C25H30FN3O3SCouleur et forme :SolidMasse moléculaire :471.59Clocinnamox mesylate
CAS :Clocinnamox mesylate: irreversible μ-opioid blocker; Ki: 0.7 nM (mouse μ), 1.9 nM (δ), 5.7 nM (κ).Formule :C30H33ClN2O7SCouleur et forme :SolidMasse moléculaire :601.11CP 85339
CAS :CP 85339 is an aspartic acid protease inhibitor for X-ray analysis of peptide-renin complexes.Formule :C31H49ClN4O6SCouleur et forme :SolidMasse moléculaire :641.26N-Acetylthyroxine
CAS :N-Acetylthyroxine is a kind of Thyroxine analogue for the treatment of diagnosing and treating diabetes.Formule :C17H13I4NO5Couleur et forme :SolidMasse moléculaire :818.91[D-Ala2]leucine-enkephalin acetate
[D-Ala2]leucine-enkephalin acetate ([D-Ala2]leucine-enkephalin acetate (64963-01-5 free base)) is a delta opioid agonist used to study the signaling pathway ofFormule :C31H43N5O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :629.65PSDalpha
PSDalpha, a conjugate of PS, TB, and 17β-estradiol, degrades ERα with peak absorption at 465 nm, effectively inhibiting MCF-7 cell growth.Formule :C44H39N3O2SCouleur et forme :SolidMasse moléculaire :673.86ER ligand-2
ER ligand-2 is a ligand for ER. It can be used in the synthesis of PROTAC ER Degrader-11.Formule :C20H23BrOCouleur et forme :SolidMasse moléculaire :359.3Bufrolin
CAS :Bufrolin is a potent GPR35 agonist, mast cell stabilizer, and anti-inflammatory research agent.Formule :C18H16N2O6Couleur et forme :SolidMasse moléculaire :356.33[Met5]-Enkephalin, amide
CAS :[Met5]-Enkephalin, amide activates δ and ζ opioid receptors; has multiple forms and varying plasma levels.Formule :C27H36N6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.68Angiotensin II (1-4), human
CAS :Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Formule :C24H37N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :551.59Glucocorticoids receptor agonist 2
CAS :Arylpyrazole-based glucocorticoid agonist with potent anti-inflammatory effects; doesn't affect insulin secretion.Formule :C25H25FN2OCouleur et forme :SolidMasse moléculaire :388.48PD 125967
CAS :PD 125967 is a renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension.Formule :C51H67N5O4Couleur et forme :SolidMasse moléculaire :814.11β-Endorphin (1-27) (human) acetate
β-Endorphin (1-27) (human) acetate, existing in the hypophysis cerebri and hypothalamus, exhibits antinociception activity.
Formule :C141H221N33O42SDegré de pureté :96.52%Couleur et forme :SolidMasse moléculaire :3082.52[Orn5]-URP acetate
[Orn5]-URP acetate is an effective and selective Urotensin-II receptor (UT) antagonist (pEC50 = 7.24). [Orn5]-URP exhibits no agonist activity.Formule :C50H66N10O12S2Degré de pureté :98.4300%Couleur et forme :SolidMasse moléculaire :1063.251-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone
CAS :Methyl-2-quinolone from Evodia rutaecarpa blocks angiotensin II receptor with 48.2 μM IC50.Formule :C25H35NOCouleur et forme :SolidMasse moléculaire :365.55PD 132002
CAS :PD 132002 is a renin inhibitor.Formule :C31H50N4O9SCouleur et forme :SolidMasse moléculaire :654.82Boc-ypgflt(O-tbu)
CAS :Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.Formule :C44H64N6O11Couleur et forme :SolidMasse moléculaire :853.01Faznolutamide
CAS :Faznolutamide is an antiandrogen agent [1] [2] .Formule :C19H17FN4O2SCouleur et forme :SolidMasse moléculaire :384.43AT-121 hydrochloride
CAS :AT-121 hydrochloride: dual nociception/mu-opioid agonist, Ki 3.67/16.49 nM, safe, non-addictive pain reliever with analgesic effects.Formule :C24H39ClN4O3SDegré de pureté :97.28% - >99.99%Couleur et forme :SolidMasse moléculaire :499.11PROTAC ERα Y537S degrader-1
CAS :PROTAC ERα Y537S degrader-1 comprises a ubiquitin E3 ligase binding group, a linker and a protein binding group.Formule :C46H49N5O6Couleur et forme :SolidMasse moléculaire :767.91(Rac)-SNC80
CAS :(Rac)-SNC80, a racemic δ-opioid agonist (K i 1.78 nM), shows potential for treating various headache disorders.Formule :C28H39N3O2Couleur et forme :SolidMasse moléculaire :449.63[Ala17]-MCH
CAS :Potent MCH receptor agonist with EC50 of 17 nM (MCH1) & 54 nM (MCH2); prefers MCH1 (Ki 0.16 nM) over MCH2 (Ki 34 nM).Formule :C97H155N29O26S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2271.71Raloxifene 4-Monomethyl Ether
CAS :Raloxifene 4-Monomethyl Ether (Compound 37), an estrogen receptor α inhibitor, has an IC50 of 1 μM against MCF-7 cells.Formule :C29H29NO4SCouleur et forme :SolidMasse moléculaire :487.61Saralasin
CAS :Competitive non-selective angiotensin II antagonist.Formule :C42H65N13O10Degré de pureté :98%Couleur et forme :PowderMasse moléculaire :912Gridegalutamide
CAS :Gridegalutamide exhibits anti-androgen and anti-tumor activities.Formule :C41H45F3N8O5SCouleur et forme :SolidMasse moléculaire :818.91Triamcinolone Benetonide
CAS :Triamcinolone benetonide is a synthetic glucocorticoid corticosteroid exhibiting potent anti-inflammatory properties.Formule :C35H42FNO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :623.71Ac-RYYRWK-NH2
CAS :Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.Formule :C49H69N15O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1012.17Dermorphin
CAS :Dermorphin is agonist of μ-opioid receptor (MOR) agonist.Formule :C40H50N8O10Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :802.87AZ'6421
CAS :"AZ'6421: A PROTAC degrading estrogen receptor alpha; potent in anti-tumor activity, useful for cancer research."Formule :C52H65F3N6O7SCouleur et forme :SolidMasse moléculaire :975.17Isomer-Turosteride
Isomer-Turosteride, a novel 5α-reductase inhibitor, reduces prostate DHT and has anticancer properties without raising T levels.Formule :C27H45N3O3Degré de pureté :98.94%Couleur et forme :SolidMasse moléculaire :459.67Naldemedine
CAS :Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. It's well tolerated with minor GI issues.Formule :C32H34N4O6Couleur et forme :SolidMasse moléculaire :570.64BigLEN(rat)
CAS :Potent GPR171 agonist (EC50 = 1.6 nM). ProSAAS-derived peptide. Regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells.Formule :C76H128N24O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1746[Orn8]-Urotensin II acetate
[Orn8]-Urotensin II acetate is a Urotensin receptor ligand and a partial agonist at Urotensin receptors.Formule :C65H87N13O20S2Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :1434.59ER degrader 5
CAS :ER degrader 5: potent ER degrader, anti-cancer, for breast cancer research.Formule :C26H18F2O4SCouleur et forme :SolidMasse moléculaire :464.48C-Type Natriuretic Peptide (1-53), human
CAS :CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.Formule :C251H417N81O71S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5801.77Latanoprost acid
CAS :Latanoprost acid is a prostanoid receptor agonist that blocks RANKL and can be used to reduce intraocular pressure.Formule :C23H34O5Degré de pureté :97.96%Couleur et forme :Pale Yellow OilMasse moléculaire :390.51Ref: TM-T15718
1mg54,00€5mg138,00€1mL*10mM (DMSO)152,00€10mg215,00€25mg429,00€50mg637,00€100mg874,00€200mg1.161,00€Neuropeptide AF (human) acetate
Neuropeptide AF (human) acetate (Neuropeptide AF (human) acetate (192387-38-5 Free base)) is an anti-opioid neuropeptide, a Neuropeptide AF (human) derivative,
Degré de pureté :99.89%Couleur et forme :SoildA 779
CAS :A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.Formule :C39H60N12O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :872.97RLA-5331
RLA-5331: iron activator with anti-androgen properties; inhibits mCRPC cell proliferation.Formule :C40H43F3N6O7SCouleur et forme :SolidMasse moléculaire :808.87PD 123177
CAS :PD 123177 is an inhibitor of Nonpeptide angiotensin AII-2.Formule :C29H28N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :480.56AKR1Cs-IN-1
AKR1Cs-IN-1 (Compound 29) is an effective and broad-spectrum inhibitor of the Aldo-Keto Reductase 1C family (AKR1C1-1C4). It achieves subtype inhibition by simultaneously binding to the SP2 and SP3 pockets, thereby blocking metabolic pathways related to drug resistance. In enzyme assays, AKR1Cs-IN-1 exhibits significant inhibitory activity with IC50 values of 0.09, 0.28, 0.05, and 0.51 µM for AKR1C1, AKR1C2, AKR1C3, and AKR1C4, respectively. The compound shows excellent resensitizing effects in doxorubicin (DOX)-resistant breast cancer cell line MCF-7/ADR, effectively enhancing the cytotoxicity of DOX. AKR1Cs-IN-1 holds promise for research on breast cancer resistance.Couleur et forme :Odour SolidCIMBA hydrochloride
CIMBA hydrochloride is a selective antagonist of the G protein-coupled estrogen receptor (GPER). It can be utilized in research related to cholesterol gallstone disease in women.Couleur et forme :Odour SolidPROTAC ER Degrader-11
CAS :PROTA CER Degrader-11 (Example 26-1) is an effective degrader of PROTA CER with an IC50 of 0.66 nM. It plays a crucial role in cancer research.Formule :C43H53N5O4Couleur et forme :SolidMasse moléculaire :703.91Tyr-W-MIF-1
CAS :Tyr-W-MIF-1, an opioid tetrapeptide, exhibits both opiate and antiopiate activities, and has been demonstrated to induce analgesia [1] [2] [5].Formule :C27H32N6O5Masse moléculaire :520.58SR-29065
CAS :SR-29065 is a REV-ERBα agonist that represses BMAL1 transcription and is used to study circadian regulation, cancer, and autoimmune disease mechanisms.Formule :C24H24F6N2O2SDegré de pureté :97.24% - 98.42%Couleur et forme :Odour SolidMasse moléculaire :518.524'-Hydroxytamoxifen TFA
4'-Hydroxytamoxifen TFA, a salt form of a metabolite of Tamoxifen, demonstrates higher affinity for ER compared to Tamoxifen itself. This compound induces non-apoptotic cytotoxicity in human endometrial adenocarcinoma cells.Formule :C28H30F3NO4Couleur et forme :SolidMasse moléculaire :501.54XOMA-213
XOMA-213 (LFA-102; X213) is a human monoclonal antibody (mAb) that specifically targets the PRLR/Prolactin Receptor. It inhibits hPRL-dependent growth of BaF3/hPRLR cells with an EC50 of 0.5 μg/mL. In models such as the Nb2-11-luc xenograft mouse and the DMBA-induced rat breast cancer model, XOMA-213 effectively suppresses PRLR signaling and tumor growth. This compound is applicable in research focused on breast cancer, hyperprolactinemia, and prostate cancer.ERD-1233
ERD-1233 is an effective oral PROTAC degrader of the estrogen receptor (estrogen receptor) with a DC50 of 0.9 nM. It plays a crucial role in research involving ER+ breast cancer.Formule :C49H53N5O6Couleur et forme :SolidMasse moléculaire :807.98[Orn8]-Urotensin II
CAS :[Orn8]-Urotensin II is a Urotensin receptor ligand and a partial agonist at Urotensin receptors.Formule :C63H83N13O18S2Couleur et forme :SolidMasse moléculaire :1374.5517-Epiestriol
CAS :17-Epiestriol, metabolite of estrone, forms via 16α-hydroxy intermediate and binds ERα and ERβ with affinity less than 17β-estradiol.Formule :C18H24O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :288.38Estetrol
CAS :Estetrol (Donesta), a fetal liver-synthesized estrogen, selectively modulates estrogen receptors and may ease menopausal symptoms.Formule :C18H24O4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :304.38Ref: TM-T15248
1mg39,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg130,00€25mg268,00€50mg462,00€100mg773,00€200mg1.044,00€Emd 55068
CAS :Emd 55068 is a synthetic antagonist of renin.Formule :C41H65N9O6Couleur et forme :SolidMasse moléculaire :780.01(S)-CVN424
CAS :(S)-CVN424 modulates GPR6, key for neurological/psychiatric research, including Parkinson's.Formule :C24H29F2N5O3Couleur et forme :SolidMasse moléculaire :473.525(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin
CAS :(d(CH2)51,Tyr(Me)2, Orn8)-Oxytocin (OVT) is an antagonist of the oxytocin receptor that finds application in the study of neurological diseases [1].Formule :C48H74N12O12S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1075.3Deltorphin acetate
Deltorphin acetate is a substance obtained from the skin secretions of a frog, Phyllomedusa bicolor and shows high selectivity and affinity for δ-opioidFormule :C46H66N10O12S2Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :1015.21Ref: TM-T20166L
1mg175,00€5mg394,00€10mg590,00€25mg1.060,00€50mg1.591,00€100mg2.387,00€200mg3.580,00€6α-Methylprednisolone 21-hemisuccinate sodium salt
CAS :6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.Formule :C26H33NaO8Degré de pureté :99.65%Couleur et forme :Lyophilized PowderMasse moléculaire :496.53Leumorphin, human
CAS :Leumorphin, human, is a potent agonist of the kappa opioid receptor (κ opioid receptor) and inhibits the contraction of the guinea pig ileum's myenteric plexus-Formule :C150H224N42O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3351.64AH 7563
CAS :AH 7563 is structurally classified as an opioid compound with analgesic properties. In mice, its ED50 for pain relief was 15.3 mg/kg when administered orally in the Phenylquinone test, and 15.5 mg/kg when injected subcutaneously in the Hot plate test.Formule :C16H24N2OCouleur et forme :SolidMasse moléculaire :260.38
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